Advances in Brief:

Immunohistochemical Analysis of in Vivo Patterns of Bcl-X Expression

Stanislaw Krajewski, Maryla Krajewska, Ahmed Shabaik, Hong-Gang Wang, Shinji Irie, Linda Fong, and John C. Reed
Cancer Res 1994 54: 5501-5507. [Abstract] [PDF]  

Rates of Apoptosis and Proliferation Vary with Caloric Intake and May Influence Incidence of Spontaneous Hepatoma in C57BL/6 x C3H F₁ Mice

S. Jill James and Levan Muskhelishvili
Cancer Res 1994 54: 5508-5510. [Abstract] [PDF]  

Tamoxifen Enhances Cell Death in Implanted MCF7 Breast Cancer by Inhibiting Endothelium Growth

E. Furman Haran, A. F. Maretzek, I. Goldberg, A. Horowitz, and H. Degani
Cancer Res 1994 54: 5511-5514. [Abstract] [PDF]  

8-Hydroxylation of Guanine Bases in Kidney and Liver DNA of Hamsters Treated with Estradiol: Role of Free Radicals in Estrogen-induced Carcinogenesis

Xueliang Han and Joachim G. Liehr
Cancer Res 1994 54: 5515-5517. [Abstract] [PDF]  

-Hydroxytamoxifen, a Metabolite of Tamoxifen with Exceptionally High DNA-binding Activity in Rat Hepatocytes

David H. Phillips, Paul L. Carmichael, Alan Hewer, Kathleen J. Cole, and Grace K. Poon
Cancer Res 1994 54: 5518-5522. [Abstract] [PDF]  

Molecular Determinants of Dysplasia in Colorectal Lesions

Jin Jen, Steve M. Powell, Nickolas Papadopoulos, Kelly J. Smith, Stanley R. Hamilton, Bert Vogelstein, and Kenneth W. Kinzler
Cancer Res 1994 54: 5523-5526. [Abstract] [PDF]  

Somatic APC and K-ras Codon 12 Mutations in Aberrant Crypt Foci from Human Colons

Andrew J. Smith, Hartley S. Stern, Mark Penner, Kazy Hay, Angela Mitri, Bharati V. Bapat, and Steven Gallinger
Cancer Res 1994 54: 5527-5530. [Abstract] [PDF]  

In Vivo Treatment with Antibody against IGF-1 Receptor Suppresses Growth of Human Rhabdomyosarcoma and Down-Regulates p34^cdc2

Thea Kalebic, Maria Tsokos, and Lee J. Helman
Cancer Res 1994 54: 5531-5534. [Abstract] [PDF]  

Growth Factor-mediated Terminal Differentiation of Chronic Myeloid Leukemia

Atul Bedi, Constance A. Griffin, James P. Barber, Milada S. Vala, Anita L. Hawkins, Saul J. Sharkis, Barbara A. Zehnbauer, and Richard J. Jones
Cancer Res 1994 54: 5535-5538. [Abstract] [PDF]  

Purified Human MSH2 Protein Binds to DNA Containing Mismatched Nucleotides

Richard Fishel, Amy Ewel, and Mary Kay Lescoe
Cancer Res 1994 54: 5539-5542. [Abstract] [PDF]  

Selective Biotransformation of Taxol to 6-Hydroxytaxol by Human Cytochrome P450 2C8

Atiqur Rahman, Kenneth R. Korzekwa, James Grogan, Frank J. Gonzalez, and James W. Harris
Cancer Res 1994 54: 5543-5546. [Abstract] [PDF]  

p16 Alterations and Deletion Mapping of 9p21–p22 in Malignant Mesothelioma

Jin Quan Cheng, Suresh C. Jhanwar, Walter M. Klein, Daphne W. Bell, Wen-Ching Lee, Deborah A. Altomare, Tsutomu Nobori, Olufunmilayo I. Olopade, Alan J. Buckler, and Joseph R. Testa
Cancer Res 1994 54: 5547-5551. [Abstract] [PDF]  

Induction of Antitumor Immunity by Recombinant Vaccinia Viruses Expressing B7-1 or B7-2 Costimulatory Molecules

James W. Hodge, Scott Abrams, Jeffrey Schlom, and Judy A. Kantor
Cancer Res 1994 54: 5552-5555. [Abstract] [PDF]  

p130/pRb2 Has Growth Suppressive Properties Similar to yet Distinctive from Those of Retinoblastoma Family Members pRb and p107

Pier Paolo Claudio, Candace M. Howard, Alfonso Baldi, Antonio De Luca, Yan Fu, Gianluigi Condorelli, Yi Sun, Nancy Colburn, Bruno Calabretta, and Antonio Giordano
Cancer Res 1994 54: 5556-5560. [Abstract] [PDF]  

Biochemistry and Biophysics:

The Role of DNA Damage and Inhibition of Poly(ADP-ribosyl)ation in Loss of Clonogenicity of Murine L929 Fibroblasts, Caused by Photodynamically Induced Oxidative Stress

Louis C. Penning, Johan W. M. Lagerberg, Jan Hein VanDierendonck, Cees J. Cornelisse, Tom M. A. R. Dubbelman, and John VanSteveninck
Cancer Res 1994 54: 5561-5567. [Abstract] [PDF]  

Increased ATP-Ubiquitin-dependent Proteolysis in Skeletal Muscles of Tumor-bearing Rats

Sandrine Temparis, Miguel Asensi, Daniel Taillandier, Eveline Aurousseau, Daniel Larbaud, Alain Obled, Daniel Béchet, Marc Ferrara, José M. Estrela, and Didier Attaix
Cancer Res 1994 54: 5568-5573. [Abstract] [PDF]  

1-Phosphatidylinositol 4-Phosphate 5-Kinase (EC 2.7.1.68): A Proliferation- and Malignancy-linked Signal Transduction Enzyme

Radhey L. Singhal, Noemi Prajda, Y. Albert Yeh, and George Weber
Cancer Res 1994 54: 5574-5578. [Abstract] [PDF]  

Carcinogenesis:

Lipofection-mediated Immortalization of Human Prostatic Epithelial Cells of Normal and Malignant Origin Using Human Papillomavirus Type 18 DNA

Philip C. Weijerman, Josee J. König, Stephen T. Wong, Hubert G. M. Niesters, and Donna M. Peehl
Cancer Res 1994 54: 5579-5583. [Abstract] [PDF]  

p53 Gene Dosage Modifies Growth and Malignant Progression of Keratinocytes Expressing the v-ras^Ha Oncogene

Wendy C. Weinberg, Christopher G. Azzoli, Namrata Kadiwar, and Stuart H. Yuspa
Cancer Res 1994 54: 5584-5592. [Abstract] [PDF]  

Genetic Analysis of an in Vitro Model System for Human Papillomavirus Type 16-associated Tumorigenesis

Sibylle Seagon and Matthias Dürst
Cancer Res 1994 54: 5593-5598. [Abstract] [PDF]  

Conservation of Histone Carcinogen Adducts during Replication: Implications for Long-Term Molecular Dosimetry

Can C. Özbal, Ivana Velic, Carlton K. SooHoo, Paul L. Skipper, and Steven R. Tannenbaum
Cancer Res 1994 54: 5599-5601. [Abstract] [PDF]  

Clinical Investigations:

Anti-inflammatory Treatment May Prolong Survival in Undernourished Patients with Metastatic Solid Tumors

K. Lundholm, J. Gelin, A. Hyltander, C. Lönnroth, R. Sandström, G. Svaninger, U. Körner, M. Gülich, I. Kärrefors, B. Norli, L. O. Hafström, J. Kewenter, L. Olbe, and L. Lundell
Cancer Res 1994 54: 5602-5606. [Abstract] [PDF]  

Experimental Therapeutics:

Overexpression of the Multidrug Resistance-associated Protein (MRP) Gene in Vincristine but not Doxorubicin-selected Multidrug-resistant Murine Erythroleukemia Cells

Christopher A. Slapak, Paula M. Fracasso, Robin L. Martell, Deborah L. Toppmeyer, Jean-Michel Lecerf, and Stuart B. Levy
Cancer Res 1994 54: 5607-5613. [Abstract] [PDF]  

Expression of Thymidine Kinase Is Essential to Low Dose Radiation Resistance of Rat Glioma Cells

Isaf Al-Nabulsi, Yoshiaki Takamiya, Yaroslav Voloshin, Anatoly Dritschilo, Robert L. Martuza, and Timothy J. Jorgensen
Cancer Res 1994 54: 5614-5617. [Abstract] [PDF]  

A Novel trans-Platinum Coordination Complex Possessing in Vitro and in Vivo Antitumor Activity

Lloyd R. Kelland, Christopher F. J. Barnard, Kirste J. Mellish, Mervyn Jones, Phyllis M. Goddard, Melanie Valenti, Alexander Bryant, Barry A. Murrer, and Kenneth R. Harrap
Cancer Res 1994 54: 5618-5622. [Abstract] [PDF]  

Vitalethine Modulates Erythropoiesis and Neoplasia

Galen D. Knight, Kevin H. Laubscher, Marilyn L. Fore, Douglas A. Clark, and Terence J. Scallen
Cancer Res 1994 54: 5623-5635. [Abstract] [PDF]  

Seemingly Diverse Activities of ß-Alethine

Galen D. Knight, Paul L. Mann, Kevin H. Laubscher, and Terence J. Scallen
Cancer Res 1994 54: 5636-5642. [Abstract] [PDF]  

Molecular Biology and Genetics:

Frequent Allelic Losses on Chromosomes 2q, 18q, and 22q in Advanced Non-Small Cell Lung Carcinoma

Masayuki Shiseki, Takashi Kohno, Ryo Nishikawa, Yuichi Sameshima, Hideaki Mizoguchi, and Jun Yokota
Cancer Res 1994 54: 5643-5648. [Abstract] [PDF]  

p53 Gene Mutation and mdm2 Gene Amplification Are Uncommon in Medulloblastoma

Adekunle M. Adesina, Josephine Nalbantoglu, and Webster K. Cavenee
Cancer Res 1994 54: 5649-5651. [Abstract] [PDF]  

Difference of Allelotype between Squamous Cell Carcinoma and Adenocarcinoma of the Lung

Shuji Sato, Yusuke Nakamura, and Eiju Tsuchiya
Cancer Res 1994 54: 5652-5655. [Abstract] [PDF]  

Genotoxic Stress Confers Preferential and Coordinate Messenger RNA Stability on the Five gadd Genes

J. Jackman, I. Alamo, Jr., and A. J. Fornace, Jr.
Cancer Res 1994 54: 5656-5662. [Abstract] [PDF]  

A Specific Defect in the Retinoic Acid Response Associated with Human Lung Cancer Cell Lines

Xiao-kun Zhang, Yi Liu, Mi-Ock Lee, and Magnus Pfahl
Cancer Res 1994 54: 5663-5669. [Abstract] [PDF]  

Tumor Biology:

Noninvasive Measurement of Interstitial pH Profiles in Normal and Neoplastic Tissue Using Fluorescence Ratio Imaging Microscopy

G. Ray Martin and Rakesh K. Jain
Cancer Res 1994 54: 5670-5674. [Abstract] [PDF]  

Amplification and Overexpression of HER-2/neu in Carcinomas of the Salivary Gland: Correlation with Poor Prognosis

Michael F. Press, Malcolm C. Pike, Gene Hung, Jian Yuan Zhou, Yanling Ma, Jay George, Jeanne Dietz-Band, William James, Dennis J. Slamon, John G. Batsakis, and Adel K. El-Naggar
Cancer Res 1994 54: 5675-5682. [Abstract] [PDF]  

Stromal Expression of c-Ets1 Transcription Factor Correlates with Tumor Invasion

Nicolas Wernert, Fréderic Gilles, Véronique Fafeur, Fatima Bouali, Marie-Berthe Raes, Charles Pyke, Thierry Dupressoir, Gerhard Seitz, Bernard Vandenbunder, and Dominique Stéhelin
Cancer Res 1994 54: 5683-5688. [Abstract] [PDF]  

MUC18, a Melanoma-Progression Associated Molecule, and Its Potential Role in Tumor Vascularization and Hematogenous Spread

Christine Sers, Gert Riethmüller, and Judith P. Johnson
Cancer Res 1994 54: 5689-5694. [Abstract] [PDF]  

Cloning of a Novel Malignant Melanoma-derived Growth-Regulatory Protein, MIA

Armin Blesch, Anja-Katrin Boßerhoff, Rainer Apfel, Christian Behl, Birgit Hessdoerfer, Angelika Schmitt, Piotr Jachimczak, Friedrich Lottspeich, Reinhard Buettner, and Ulrich Bogdahn
Cancer Res 1994 54: 5695-5701. [Abstract] [PDF]  

A Potential Marker Protease of Invasiveness, Separase, Is Localized on Invadopodia of Human Malignant Melanoma Cells

Wayne L. Monsky, Chen-Yong Lin, Atsuko Aoyama, Thomas Kelly, Steven K. Akiyama, Susette C. Mueller, and Wen-Tien Chen
Cancer Res 1994 54: 5702-5710. [Abstract] [PDF]  

Inhibition of Breast Cancer Cell Growth by Combined Treatment with Vitamin D₃ Analogues and Tamoxifen

Trudy Vink-van Wijngaarden, Huibert A. P. Pols, Cok J. Buurman, Gert Jan C. M. van den Bemd, Lambert C. J. Dorssers, Jan C. Birkenhäger, and Johannes P. T. M. van Leeuwen
Cancer Res 1994 54: 5711-5717. [Abstract] [PDF]  

Basic Fibroblast Growth Factor Increases the Multiplication and Migration of a Serum-free Derivative of CACO-2 but Does Not Affect Differentiation

Gordon C. Jayson, Gareth S. Evans, Philip W. Pemberton, Robert W. Lobley, and Terence Allen
Cancer Res 1994 54: 5718-5723. [Abstract] [PDF]  

Calorie Intake during Mammary Development Influences Cancer Risk: Lasting Inhibition of C3H/HeOu Mammary Tumorigenesis by Peripubertal Calorie Restriction

Robert W. Engelman, Noorbibi K. Day, and Robert A. Good
Cancer Res 1994 54: 5724-5730. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1994 54: 5731-5732. [PDF]  

Erratum

Cancer Res 1994 54: 5733 [PDF]  

Announcements:

Calendar of Events

Cancer Res 1994 54: 5733 [PDF]  

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