Advances in Brief:

Characterization and Localization of the TCL-1 Oncogene Product

Tie-bo Fu, Laura Virgilio, Maria Grazia Narducci, Antonio Facchiano, Giandomenico Russo, and Carlo M. Croce
Cancer Res 1994 54: 6297-6301. [Abstract] [PDF]  

Sialyl-Tn Antigen Expression Occurs Early during Human Mammary Carcinogenesis and Is Associated with High Nuclear Grade and Aneuploidy

Se-Heon Cho, Aysegul Sahin, Gabriel N. Hortobagyi, Walter N. Hittelman, and Kapil Dhingra
Cancer Res 1994 54: 6302-6305. [Abstract] [PDF]  

Sensitive Nested Reverse Transcription Polymerase Chain Reaction Detection of Circulating Prostatic Tumor Cells: Comparison of Prostate-specific Membrane Antigen and Prostate-specific Antigen-based Assays

Ron S. Israeli, Wilson H. Miller, Jr., Sai L. Su, C. Thomas Powell, William R. Fair, Dan S. Samadi, Robert F. Huryk, Anthony DeBlasio, Elizabeth T. Edwards, Gilbert J. Wise, and Warren D. W. Heston
Cancer Res 1994 54: 6306-6310. [Abstract] [PDF]  

Preloading with L-Tyrosine Increases the Uptake of Boronophenylalanine in Mouse Melanoma Cells

Manfred Papaspyrou, Ludwig E. Feinendegen, and Hans-W. Müller-Gärtner
Cancer Res 1994 54: 6311-6314. [Abstract] [PDF]  

Instability of Microsatellites in Rat Colon Tumors Induced by Heterocyclic Amines

Federico Canzian, Toshikazu Ushijima, Tadao Serikawa, Keiji Wakabayashi, Takashi Sugimura, and Minako Nagao
Cancer Res 1994 54: 6315-6317. [Abstract] [PDF]  

Boron Neutron Capture Therapy: Boron Biodistribution and Pharmacokinetics of Na₂B₁₂H₁₁SH in Patients with Glioblastoma

Klaus Haselsberger, Herbert Radner, and Gerhard Pendl
Cancer Res 1994 54: 6318-6320. [Abstract] [PDF]  

CDKN2 (p16/MTS1) Gene Deletion or CDK4 Amplification Occurs in the Majority of Glioblastomas

Esther E. Schmidt, Koichi Ichimura, Guido Reifenberger, and V. Peter Collins
Cancer Res 1994 54: 6321-6324. [Abstract] [PDF]  

Detection of Sequence-Specific Antitumor Alkylating Agent DNA Damage from Cells Treated in Culture and from a Patient

G. J. Bubley, G. K. Ogata, N. P. Dupuis, and B. A. Teicher
Cancer Res 1994 54: 6325-6329. [Abstract] [PDF]  

Kinetics of the in Vivo Interconversion of the Carboxylate and Lactone Forms of Irinotecan (CPT-11) and of Its Metabolite SN-38 in Patients

Laurent P. Rivory, Etienne Chatelut, Pierre Canal, Anne Mathieu-Boué, and Jacques Robert
Cancer Res 1994 54: 6330-6333. [Abstract] [PDF]  

Somatostatin Analogue Octreotide Enhances the Antineoplastic Effects of Tamoxifen and Ovariectomy on 7,12-Dimethylbenz(a)anthracene-induced Rat Mammary Carcinomas

G. Weckbecker, L. Tolcsvai, B. Stolz, M. Pollak, and C. Bruns
Cancer Res 1994 54: 6334-6337. [Abstract] [PDF]  

Mutation Rate of the CDKN2 Gene in Malignant Gliomas

Cristiana Giani and Gaetano Finocchiaro
Cancer Res 1994 54: 6338-6339. [Abstract] [PDF]  

Identification of a Microsatellite Instability Phenotype in Meningiomas

Mark J. Pykett, Maureen Murphy, Peter R. Harnish, and Donna L. George
Cancer Res 1994 54: 6340-6343. [Abstract] [PDF]  

Molecular Characterization of Prostate-specific Antigen Messenger RNA Expressed in Breast Tumors

Maria Monne, Carlo M. Croce, He Yu, and Eleftherios P. Diamandis
Cancer Res 1994 54: 6344-6347. [Abstract] [PDF]  

Mcl-1, a Member of the Bcl-2 Family, Delays Apoptosis Induced by c-Myc Overexpression in Chinese Hamster Ovary Cells

Jason E. Reynolds, Tao Yang, Liping Qian, J. David Jenkinson, Ping Zhou, Alan Eastman, and Ruth W. Craig
Cancer Res 1994 54: 6348-6352. [Abstract] [PDF]  

Deletion of p16 and p15 Genes in Brain Tumors

Jin Jen, J. Wade Harper, Sandra H. Bigner, Darell D. Bigner, Nickolas Papadopoulos, Sanford Markowitz, James K. V. Willson, Kenneth W. Kinzler, and Bert Vogelstein
Cancer Res 1994 54: 6353-6358. [Abstract] [PDF]  

Characterization of Poliovirus Replicons Encoding Carcinoembryonic Antigen

David C. Ansardi, Zina Moldoveanu, Donna C. Porter, Donald E. Walker, Robert M. Conry, Albert F. LoBuglio, Sylvia McPherson, and Casey D. Morrow
Cancer Res 1994 54: 6359-6364. [Abstract] [PDF]  

A Ribozyme Which Discriminates in Vitro between PML/RAR, the t(15;17)-associated Fusion RNA of Acute Promyelocytic Leukemia, and PML and RAR, the Transcripts from the Nonrearranged Alleles

Umberto Pace, Jeffrey M. Bockman, Barbara J. MacKay, Wilson H. Miller, Jr., Ethan Dmitrovsky, and Allan R. Goldberg
Cancer Res 1994 54: 6365-6369. [Abstract] [PDF]  

Loss of Heterozygosity in Human Primary Prostate Carcinomas: A Possible Tumor Suppressor Gene at 7q31.1

Jean C. Zenklusen, Janet C. Thompson, Patricia Troncoso, Jacob Kagan, and Claudio J. Conti
Cancer Res 1994 54: 6370-6373. [Abstract] [PDF]  

Special Lecture:

The Search for BRCA1

Lori S. Friedman, Elizabeth A. Ostermeyer, Eric D. Lynch, Csilla I. Szabo, Lee A. Anderson, Patrick Dowd, Ming K. Lee, Sarah E. Rowell, Jeff Boyd, and Mary-Claire King
Cancer Res 1994 54: 6374-6382. [Abstract] [PDF]  

Biochemistry and Biophysics:

Insulin Protects against Hepatic Bioenergetic Deterioration Induced by Cancer Cachexia: An in Vivo ³¹P Magnetic Resonance Spectroscopy Study

Manfred Brauer, Richard I. Inculet, Gopal Bhatnagar, Gregory D. Marsh, Albert A. Driedger, and R. Terry Thompson
Cancer Res 1994 54: 6383-6386. [Abstract] [PDF]  

Quantitative Analysis of Protein Synthesis Inhibition by Transferrin-Toxin Conjugates

Parvin T. Yazdi and Regina M. Murphy
Cancer Res 1994 54: 6387-6394. [Abstract] [PDF]  

Carcinogenesis:

An Overexpressed N-ras Proto-oncogene Cooperates with N-Methylnitrosourea in Mouse Mammary Carcinogenesis

Ramon Mangues, Jesse M. Kahn, Irving Seidman, and Angel Pellicer
Cancer Res 1994 54: 6395-6401. [Abstract] [PDF]  

Nodularin, a Potent Inhibitor of Protein Phosphatases 1 and 2A, Is a New Environmental Carcinogen in Male F344 Rat Liver

Tetsuya Ohta, Eisaburo Sueoka, Naoyuki Iida, Atsumasa Komori, Masami Suganuma, Rie Nishiwaki, Masae Tatematsu, Seong-Jin Kim, Wayne W. Carmichael, and Hirota Fujiki
Cancer Res 1994 54: 6402-6406. [Abstract] [PDF]  

Altered Oxidative Stress Responses in Nickel-resistant Mammalian Cells

Konstantin Salnikow, Min Gao, Vika Voitkun, Xi Huang, and Max Costa
Cancer Res 1994 54: 6407-6412. [Abstract] [PDF]  

Alterations in Murine Keratinocyte Differentiation Induced by Activated ras^Ha Genes Are Mediated by Protein Kinase C-

Andrzej A. Dlugosz, Christina Cheng, Erin K. Williams, Alpa G. Dharia, Mitchell F. Denning, and Stuart H. Yuspa
Cancer Res 1994 54: 6413-6420. [Abstract] [PDF]  

Clinical Investigations:

Clinical Pharmacokinetics of Cyclophosphamide and Metabolites with and without SR-2508

Kenneth K. Chan, Phillip S. Hong, Kendra Tutsch, and Donald L. Trump
Cancer Res 1994 54: 6421-6429. [Abstract] [PDF]  

Analysis of the Energy Balance in Lung Cancer Patients

Agnes J. Staal-van den Brekel, Annemie M. W. J. Schols, Guul P. M. ten Velde, Wim A. Buurman, and Emiel F. M. Wouters
Cancer Res 1994 54: 6430-6433. [Abstract] [PDF]  

Endocrinology:

Ectopic Vasopressin Expression in MMTV-Wnt-1 Transgenic Mice Modifies Mammary Tumor Differentiation and Pathology

Kum-Fai Chooi, David A. Carter, Shib Biswas, Stafford L. Lightman, Mei-Yin Ho, and David Murphy
Cancer Res 1994 54: 6434-6440. [Abstract] [PDF]  

Unsaturated Fatty Acids Are Required for Continuous Proliferation of Transformed Androgen-dependent Cells by Fibroblast Growth Factor Family Proteins

Soji Kasayama, Masafumi Koga, Haruhiko Kouhara, Satoru Sumitani, Katsuya Wada, Tadamitsu Kishimoto, and Bunzo Sato
Cancer Res 1994 54: 6441-6445. [Abstract] [PDF]  

Experimental Therapeutics:

Increasing 1-ß-D-Arabinofuranosylcytosine Efficacy by Scheduled Dosing Intervals Based on Direct Measurements of Bone Marrow Cell Kinetics

Paolo Ubezio, Giovanna Tagliabue, Bila Schechter, and Zvia Agur
Cancer Res 1994 54: 6446-6451. [Abstract] [PDF]  

Enhancement of the Antineoplastic Effect of Mitomycin C by Dietary Fat

Yu Shao, Lani Pardini, and Ronald S. Pardini
Cancer Res 1994 54: 6452-6457. [Abstract] [PDF]  

Induction of Hypoxia in Experimental Murine Tumors by the Nitric Oxide Synthase Inhibitor, N^G-Nitro-L-arginine

Pauline J. Wood, Janet M. Sansom, Susan A. Butler, Ian J. Stratford, Shirley M. Cole, Csaba Szabo, Christoph Thiemermann, and Gerald E. Adams
Cancer Res 1994 54: 6458-6463. [Abstract] [PDF]  

Cross-Resistance between Cisplatin and Antimony in a Human Ovarian Carcinoma Cell Line

Peter Naredi, Dennis D. Heath, Robert E. Enns, and Stephen B. Howell
Cancer Res 1994 54: 6464-6468. [Abstract] [PDF]  

Combined Interleukin-1ß/Interleukin-6 Treatment in Mice: Synergistic Myelostimulatory Activity and Myelorestorative Effect after Cyclophosphamide-induced Myelosuppression

E. Tritarelli, G. Greco, U. Testa, F. Belardelli, C. Peschle, and E. Proietti
Cancer Res 1994 54: 6469-6476. [Abstract] [PDF]  

Immunology:

Specificity and Longevity of Antitumor Immune Responses Induced by B7-transfected Tumors

Sarah E. Townsend, Fannie W. Su, Jeanette M. Atherton, and James P. Allison
Cancer Res 1994 54: 6477-6483. [Abstract] [PDF]  

Molecular Biology and Genetics:

Deletion Mapping on the Short Arm of Chromosome 3 in Squamous Cell Carcinoma of the Oral Cavity

Chu Lee Wu, Philip Sloan, Andrew P. Read, Rodney Harris, and Nalin Thakker
Cancer Res 1994 54: 6484-6488. [Abstract] [PDF]  

Genetic Analysis of Liver Tumorigenesis in SV40 T Antigen Transgenic Mice Implies a Role for Imprinted Genes

William A. Held, Joanne Pazik, Jodi Giancola O'Brien, Kimberly Kerns, Margaret Gobey, Ronald Meis, Luella Kenny, and Youcef Rustum
Cancer Res 1994 54: 6489-6495. [Abstract] [PDF]  

Chromosome 8 Alterations Accompany Tumorigenesis in Renin-SV40 T Antigen Transgenic Mice

William A. Held, Jodi Giancola O'Brien, Kimberly Kerns, John F. Gallagher, Curt D. Sigmund, and Kenneth W. Gross
Cancer Res 1994 54: 6496-6499. [Abstract] [PDF]  

Characterization of the CHOP Breakpoints and Fusion Transcripts in Myxoid Liposarcomas with the 12;16 Translocation

Ioannis Panagopoulos, Nils Mandahl, David Ron, Mattias Höglund, Mef Nilbert, Fredrik Mertens, Felix Mitelman, and Pierre Åman
Cancer Res 1994 54: 6500-6503. [Abstract] [PDF]  

Transfection of Thrombospondin 1 Complementary DNA into a Human Breast Carcinoma Cell Line Reduces Primary Tumor Growth, Metastatic Potential, and Angiogenesis

Debra L. Weinstat-Saslow, Vivian S. Zabrenetzky, Kenneth VanHoutte, William A. Frazier, David D. Roberts, and Patricia S. Steeg
Cancer Res 1994 54: 6504-6511. [Abstract] [PDF]  

DNA Binding and Transactivation Activity of A-myb, a c-myb-related Gene

Xiao-Ping Ma and Bruno Calabretta
Cancer Res 1994 54: 6512-6516. [Abstract] [PDF]  

Tumor Biology:

Pericellular pH Affects Distribution and Secretion of Cathepsin B in Malignant Cells

Jurij Rozhin, Mansoureh Sameni, Grace Ziegler, and Bonnie F. Sloane
Cancer Res 1994 54: 6517-6525. [Abstract] [PDF]  

The Role of Transforming Growth Factor ß₁ in the Fibroblastic Reaction Associated with Rat Colorectal Tumor Development

Blandine Lieubeau, Laure Garrigue, Isabelle Barbieux, Khaled Meflah, and Marc Gregoire
Cancer Res 1994 54: 6526-6532. [Abstract] [PDF]  

Variant Type of Sialyl Lewis X Antigen Expressed on Adult T Cell Leukemia Cells Is Associated with Skin Involvement

Yoshitaka Furukawa, Mitsutoshi Tara, Katsuyuki Ohmori, and Reiji Kannagi
Cancer Res 1994 54: 6533-6538. [Abstract] [PDF]  

Impact of Urokinase-Type Plasminogen Activator and Its Inhibitor Type 1 on Prognosis in Cervical Cancer of the Uterus

Hiroshi Kobayashi, Suguru Fujishiro, and Toshihiko Terao
Cancer Res 1994 54: 6539-6548. [Abstract] [PDF]  

9-cis Retinoic Acid Inhibits Growth of Breast Cancer Cells and Down-Regulates Estrogen Receptor RNA and Protein

Mark Rubin, Eyal Fenig, Angelika Rosenauer, Celia Menendez-Botet, Charles Achkar, Jacqueline M. Bentel, Joachim Yahalom, John Mendelsohn, and Wilson H. Miller, Jr.
Cancer Res 1994 54: 6549-6556. [Abstract] [PDF]  

Effects of Linoleic Acid on the Growth and Metastasis of Two Human Breast Cancer Cell Lines in Nude Mice and the Invasive Capacity of These Cell Lines in Vitro

David P. Rose, Jeanne M. Connolly, and Xin-Hua Liu
Cancer Res 1994 54: 6557-6562. [Abstract] [PDF]  

Episomal Expression of Sense and Antisense Insulin-like Growth Factor (IGF)-binding Protein-4 Complementary DNA Alters the Mitogenic Response of a Human Colon Cancer Cell Line (HT-29) by Mechanisms That Are Independent of and Dependent upon IGF-I

Pomila Singh, Bosong Dai, Bharati Dhruva, and Steven G. Widen
Cancer Res 1994 54: 6563-6570. [Abstract] [PDF]  

Enhanced Expression of the Tie Receptor Tyrosine Kinase Messenger RNA in the Vascular Endothelium of Metastatic Melanomas

Arja Kaipainen, Tatyana Vlaykova, Erika Hatva, Tom Böhling, Antti Jekunen, Seppo Pyrhönen, and Kari Alitalo
Cancer Res 1994 54: 6571-6577. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1994 54: 6578-6581. [PDF]  

Acknowledgment to Reviewers

Cancer Res 1994 54: 6582-6590. [PDF]  

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