Advances in Brief:

A Candidate Tumor Suppressor Gene in Human Breast Cancers

David R. Schott, Julielani Ngo Chang, Guoren Deng, Wayne Kurisu, Wen-Lin Kuo, Joe Gray, and Helene S. Smith
Cancer Res 1994 54: 1393-1396. [Abstract] [PDF]  

Loci Associated with Malignant Progression in Astrocytomas: A Candidate on Chromosome 19q

Andreas von Deimling, Bernhard Bender, Rolf Jahnke, Andreas Waha, Jürgen Kraus, Steffen Albrecht, Ruth Wellenreuther, Frank Faßbender, Judith Nagel, Anil G. Menon, David N. Louis, Doris Lenartz, Johannes Schramm, and Otmar D. Wiestler
Cancer Res 1994 54: 1397-1401. [Abstract] [PDF]  

Correlation between E2F-1 Requirement in the S Phase and E2F-1 Transactivation of Cell Cycle-related Genes in Human Cells

Arturo Sala, Nicholas C. Nicolaides, Andrew Engelhard, Teresa Bellon, Deirdre C. Lawe, Andrew Arnold, Xavier Graña, Antonio Giordano, and Bruno Calabretta
Cancer Res 1994 54: 1402-1406. [Abstract] [PDF]  

Epidermal Growth Factor Modifies Cell Cycle Control in A431 Human Squamous Carcinoma Cells Damaged by Ionizing Radiation

Keith R. Laderoute, Walter A. Ausserer, A. Merrill Knapp, Tandora D. Grant, and Robert M. Sutherland
Cancer Res 1994 54: 1407-1411. [Abstract] [PDF]  

Ionizing Radiation Induces Rapid Tyrosine Phosphorylation of p34^cdc2

Surender Kharbanda, Ahamed Saleem, Rakesh Datta, Zhi-Min Yuan, Ralph Weichselbaum, and Donald Kufe
Cancer Res 1994 54: 1412-1414. [Abstract] [PDF]  

Estramustine Sensitizes Human Glioblastoma Cells to Irradiation

Daizo Yoshida, Joseph Piepmeier, and Marc Weinstein
Cancer Res 1994 54: 1415-1417. [Abstract] [PDF]  

Constitutive DNA Binding of the Low Mobility Forms of the AP-1 and SP-1 Transcription Factors in HL60 Cells Resistant to 1-ß-D-Arabinofuranosylcytosine

Sarah S. Kolla and George P. Studzinski
Cancer Res 1994 54: 1418-1421. [Abstract] [PDF]  

Homozygous Deletions of 9p21 in Primary Human Bladder Tumors Detected by Comparative Multiplex Polymerase Chain Reaction

Paul Cairns, Kaori Tokino, Yolanda Eby, and David Sidransky
Cancer Res 1994 54: 1422-1424. [Abstract] [PDF]  

Hypoxia Causes the Activation of Nuclear Factor B through the Phosphorylation of IB on Tyrosine Residues

Albert C. Koong, Eunice Y. Chen, and Amato J. Giaccia
Cancer Res 1994 54: 1425-1430. [Abstract] [PDF]  

Perspectives in Cancer Research:

Camptothecins: From Bench Research to Hospital Wards

Milan Potmesil
Cancer Res 1994 54: 1431-1439. [PDF]  

Carcinogenesis:

Histogenesis of Induced Prostate and Seminal Vesicle Carcinoma in Lobund-Wistar Rats: A System for Histological Scoring and Grading

Michael V. Slayter, Mario A. Anzano, Kenji Kadomatsu, Joseph M. Smith, and Michael B. Sporn
Cancer Res 1994 54: 1440-1445. [Abstract] [PDF]  

Chemoprevention of Spontaneous Endometrial Cancer in Female Donryu Rats by Dietary Indole-3-carbinol

Toshihiro Kojima, Takuji Tanaka, and Hideki Mori
Cancer Res 1994 54: 1446-1449. [Abstract] [PDF]  

Clinical Investigations:

A Phase I Study of Swainsonine in Patients with Advanced Malignancies

Paul E. Goss, Jose Baptiste, Berny Fernandes, Michael Baker, and James W. Dennis
Cancer Res 1994 54: 1450-1457. [Abstract] [PDF]  

Endocrinology:

Antiestrogenic Effects of All-trans-Retinoic Acid and 1,25-Dihydroxyvitamin D₃ in Breast Cancer Cells Occur at the Estrogen Response Element Level but through Different Molecular Mechanisms

Ediz Demirpence, Patrick Balaguer, Françoise Trousse, Jean-Claude Nicolas, Michel Pons, and Didier Gagne
Cancer Res 1994 54: 1458-1464. [Abstract] [PDF]  

Experimental Therapeutics:

AA1, A Newly Synthesized Monovalent Lipophilic Cation, Expresses Potent in Vivo Antitumor Activity

Xiaocheng Sun, James R. Wong, Kaili Song, Julian Hu, Keith D. Garlid, and Lan Bo Chen
Cancer Res 1994 54: 1465-1471. [Abstract] [PDF]  

Potentiation of the Antitumor Activity of 5-Fluorouracil in Colon Carcinoma Cells by the Combination of Interferon and Deoxyribonucleosides Results from Complementary Effects on Thymidine Phosphorylase

Edward L. Schwartz, Nicole Baptiste, Carolyn J. O'Connor, Scott Wadler, and Brian A. Otter
Cancer Res 1994 54: 1472-1478. [Abstract] [PDF]  

Antitumor Activity of Free and Liposome-entrapped Annamycin, a Lipophilic Anthracycline Antibiotic with Non-Cross-Resistance Properties

Yiyu Zou, Yi He Ling, Nguyen T. Van, Waldemar Priebe, and Roman Perez-Soler
Cancer Res 1994 54: 1479-1484. [Abstract] [PDF]  

Regression of Human Breast Tumor Xenografts in Response to (E)-2'-Deoxy-2'-(fluoromethylene)cytidine, an Inhibitor of Ribonucleoside Diphosphate Reductase

Alan J. Bitonti, Jennifer A. Dumont, Tammy L. Bush, Elizabeth A. Cashman, Doreen E. Cross-Doersen, Paul S. Wright, Donald P. Matthews, James R. McCarthy, and Donald A. Kaplan
Cancer Res 1994 54: 1485-1490. [Abstract] [PDF]  

Altered Cytotoxicity of (2-Chloroethyl)-3-sarcosinamide-1-nitrosourea in Human Glioma Cell Lines SK-MG-1 and SKI-1 Correlates with Differential Transport Kinetics

Adrian J. Noë, Areti Malapetsa, and Lawrence C. Panasci
Cancer Res 1994 54: 1491-1496. [Abstract] [PDF]  

cis-Diamminedichloroplatinum(II) Resistant Human Tumor Cell Lines Are Collaterally Sensitive to PtCl₄(Rh-123)₂: Evidence for Mitochondrial Involvement

Gulshan Ara, Tetsuya Kusumoto, Timothy T. Korbut, Francisco Cullere-Luengo, and Beverly A. Teicher
Cancer Res 1994 54: 1497-1502. [Abstract] [PDF]  

Tumors Expressing the Cytosine Deaminase Suicide Gene Can Be Eliminated in Vivo with 5-Fluorocytosine and Induce Protective Immunity to Wild Type Tumor

Craig A. Mullen, Melissa M. Coale, Robert Lowe, and R. Michael Blaese
Cancer Res 1994 54: 1503-1506. [Abstract] [PDF]  

5-Ethynyluracil (776C85): Modulation of 5-Fluorouracil Efficacy and Therapeutic Index in Rats Bearing Advanced Colorectal Carcinoma

Shousong Cao, Youcef M. Rustum, and Thomas Spector
Cancer Res 1994 54: 1507-1510. [Abstract] [PDF]  

Immunology:

Chimeric Anti-Ganglioside G_M2 Antibody with Antitumor Activity

Kazuyasu Nakamura, Masamichi Koike, Kenya Shitara, Yoshihisa Kuwana, Kazumi Kiuragi, Shinobu Igarashi, Mamoru Hasegawa, and Nobuo Hanai
Cancer Res 1994 54: 1511-1516. [Abstract] [PDF]  

Physiologically Based Pharmacokinetic Model for Specific and Nonspecific Monoclonal Antibodies and Fragments in Normal Tissues and Human Tumor Xenografts in Nude Mice

Laurence T. Baxter, Hui Zhu, Daniel G. Mackensen, and Rakesh K. Jain
Cancer Res 1994 54: 1517-1528. [Abstract] [PDF]  

Activation of Natural Killer Cells by Mouse Mammary Tumor Virus C4 in BALB/c and T-Cell Receptor Vß2-transgenic Mice

Randall Gill, Hong Wang, Horst Bluethmann, Antonio Iglesias, and Wei-Zen Wei
Cancer Res 1994 54: 1529-1535. [Abstract] [PDF]  

MDR1 Gene-specific Monoclonal Antibody C494 Cross-Reacts with Pyruvate Carboxylase

Vailabhaneni V. Rao, Douglas C. Anthony, and David Piwnica-Worms
Cancer Res 1994 54: 1536-1541. [Abstract] [PDF]  

Molecular Biology and Genetics:

Isochromosome 12p-positive Pineal Germ Cell Tumor

Tjerk W. A. de Bruin, Rosalyn M. Slater, Rafaella Defferrari, Ad Geurts van Kessel, Ron F. Suijkerbuijk, Gerard Jansen, Bauke de Jong, and J. Wolter Oosterhuis
Cancer Res 1994 54: 1542-1544. [Abstract] [PDF]  

Aberration of Genomic DNA in Association with Human Hepatocellular Carcinomas Detected by 2-Dimensional Gel Analysis

Hisaki Nagai, Mathurose Ponglikitmongkol, Eiji Mita, Yoshitaka Ohmachi, Hirohide Yoshikawa, Reiko Saeki, Yasuhiro Yumoto, Toshio Nakanishi, and Kenichi Matsubara
Cancer Res 1994 54: 1545-1550. [Abstract] [PDF]  

p53 Mutations in Lung Tumors: Relationship to Putative Susceptibility Markers for Cancer

David Ryberg, Elin Kure, Sigrid Lystad, Vidar Skaug, Lodve Stangeland, Inderjit Mercy, Anne-Lise Børresen, and Aage Haugen
Cancer Res 1994 54: 1551-1555. [Abstract] [PDF]  

K-ras and p53 Gene Mutations in Pancreatic Cancer: Ductal and Nonductal Tumors Progress through Different Genetic Lesions

N. S. Pellegata, F. Sessa, B. Renault, M. Bonato, B. E. Leone, E. Solcia, and G. N. Ranzani
Cancer Res 1994 54: 1556-1560. [Abstract] [PDF]  

Inhibition of Human Melanoma Growth and Metastasis in Vivo by Anti-CD44 Monoclonal Antibody

Yajun Guo, Jing Ma, Jinhong Wang, Xiaoyan Che, Jagad Narula, Michael Bigby, Mengchao Wu, and Man-Sun Sy
Cancer Res 1994 54: 1561-1565. [Abstract] [PDF]  

Increased Androgen Receptor Activity and Altered c-myc Expression in Prostate Cancer Cells after Long-Term Androgen Deprivation

John Kokontis, Kenji Takakura, Nissim Hay, and Shutsung Liao
Cancer Res 1994 54: 1566-1573. [Abstract] [PDF]  

Tumor Biology:

Endogenous 12(S)-HETE Production by Tumor Cells and Its Role in Metastasis

Yong Q. Chen, Zofia M. Duniec, Bin Liu, Wolfgang Hagmann, Xiang Gao, Katsu-ichi Shimoji, Lawrence J. Marnett, Carl R. Johnson, and Kenneth V. Honn
Cancer Res 1994 54: 1574-1579. [Abstract] [PDF]  

Anti-Fas on Nonhematopoietic Tumors: Levels of Fas/APO-1 and bcl-2 Are Not Predictive of Biological Responsiveness

Laurie B. Owen-Schaub, Robert Radinsky, Ewa Kruzel, Karen Berry, and Shin Yonehara
Cancer Res 1994 54: 1580-1586. [Abstract] [PDF]  

Altered Expression of Estrogen-regulated Genes in a Tamoxifen-resistant and ICI 164,384 and ICI 182,780 Sensitive Human Breast Cancer Cell Line, MCF-7/TAM^R-1

Anne E. Lykkesfeldt, Mogens W. Madsen, and Per Briand
Cancer Res 1994 54: 1587-1595. [Abstract] [PDF]  

Differential Sensitivity to the Induction of Apoptosis by Cisplatin in Proliferating and Quiescent Immature Rat Thymocytes Is Independent of the Levels of Drug Accumulation and DNA Adduct Formation

Dyfed L. Evans, Michael Tilby, and Caroline Dive
Cancer Res 1994 54: 1596-1603. [Abstract] [PDF]  

Early Mutational Activation of the c-Ki-ras Oncogene in Endometrial Carcinoma

Bridgette D. Duggan, Juan C. Felix, Laila I. Muderspach, Jen-Lan Tsao, and Darryl K. Shibata
Cancer Res 1994 54: 1604-1607. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1994 54: 1608-1610. [PDF]  

Erratum

Cancer Res 1994 54: 1610 [PDF]  

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