Advances in Brief:

Induction of Chemosensitivity in Human Lung Cancer Cells in Vivo by Adenovirus-mediated Transfer of the Wild-Type p53 Gene

Toshiyoshi Fujiwara, Elizabeth A. Grimm, Tapas Mukhopadhyay, Wei-Wei Zhang, Laurie B. Owen-Schaub, and Jack A. Roth
Cancer Res 1994 54: 2287-2291. [Abstract] [PDF]  

17p Allelic Losses in Diploid Cells of Patients with Barrett's Esophagus Who Develop Aneuploidy

Patricia L. Blount, Patricia C. Galipeau, Carissa A. Sanchez, Katayoun Neshat, Douglas S. Levine, Jing Yin, Hiroyuki Suzuki, John M. Abraham, Stephen J. Meltzer, and Brian J. Reid
Cancer Res 1994 54: 2292-2295. [Abstract] [PDF]  

Induction of Resistance to Fluorodeoxyuridine Cytotoxicity and DNA Damage in Human Tumor Cells by Expression of Escherichia coli Deoxyuridinetriphosphatase

Christine E. Canman, Eric H. Radany, Leslie A. Parsels, Mary A. Davis, Theodore S. Lawrence, and Jonathan Maybaum
Cancer Res 1994 54: 2296-2298. [Abstract] [PDF]  

Suppression of Metastasis of Rat Prostatic Cancer by Introducing Human Chromosome 8

Tomohiko Ichikawa, Naoki Nihei, Hiroyoshi Suzuki, Mitsuo Oshimura, Mitsura Emi, Yusuke Nakamura, Isamu Hayata, John T. Isaacs, and Jun Shimazaki
Cancer Res 1994 54: 2299-2302. [Abstract] [PDF]  

An Upstream Region of the Enoyl-Coenzyme A Hydratase/3-Hydroxyacyl-Coenzyme A Dehydrogenase Gene Directs Luciferase Expression in Liver in Response to Peroxisome Proliferators in Transgenic Mice

Keith Alvares, Chungyang Fan, Soheil S. Dadras, Anjana V. Yeldandi, Richard A. Rachubinski, John P. Capone, Suresh Subramani, Philip M. Iannaccone, M. Sambasiva Rao, and Janardan K. Reddy
Cancer Res 1994 54: 2303-2306. [Abstract] [PDF]  

Homozygous and Hemizygous Deletions of 9p Centromeric to the Interferon Genes in Lung Cancer

Leeanne J. Mead, Matthew T. Gillespie, Louis B. Irving, and Lynda J. Campbell
Cancer Res 1994 54: 2307-2309. [Abstract] [PDF]  

Human Lactoferrin Inhibits Growth of Solid Tumors and Development of Experimental Metastases in Mice

JoAnn Bezault, Ramesh Bhimani, Jay Wiprovnick, and Philip Furmanski
Cancer Res 1994 54: 2310-2312. [Abstract] [PDF]  

Overproduction of Ornithine Decarboxylase Caused by Relief of Translational Repression Is Associated with Neoplastic Transformation

Lisa M. Shantz and Anthony E. Pegg
Cancer Res 1994 54: 2313-2316. [Abstract] [PDF]  

Disruption of G₀-G₁ Arrest in Quiescent and Senescent Cells Treated with Phosphatase Inhibitors

Cynthia A. Afshari and J. Carl Barrett
Cancer Res 1994 54: 2317-2321. [Abstract] [PDF]  

Homozygous Deletion on Chromosome 9p and Loss of Heterozygosity on 9q, 6p, and 6q in Primary Human Small Cell Lung Cancer

Adrian Merlo, Edward Gabrielson, Mack Mabry, Robin Vollmer, Stephen B. Baylin, and David Sidransky
Cancer Res 1994 54: 2322-2326. [Abstract] [PDF]  

Sequence Analysis of the Breakpoint Cluster Region in the ALL-1 Gene Involved in Acute Leukemia

Y. Gu, H. Alder, T. Nakamura, S. A. Schichman, R. Prasad, O. Canaani, H. Saito, C. M. Croce, and E. Canaani
Cancer Res 1994 54: 2327-2330. [Abstract] [PDF]  

Loss of Heterozygosity for Chromosomes 16q and 1p in Wilms' Tumors Predicts an Adverse Outcome

Paul E. Grundy, Perry E. Telzerow, Norman Breslow, Jamie Moksness, Vicki Huff, and Malcolm C. Paterson
Cancer Res 1994 54: 2331-2333. [Abstract] [PDF]  

Biochemistry and Biophysics:

The Subunit of GTP-binding Protein G_o in Neuroblastoma: Correlation with Advanced Disease Stage

Yukio Ishiguro, Kanefusa Kato, Tomiko Asano, Hiroshi Akatsuka, Hiroyuki Iwata, Fujio Ito, and Takahiro Ito
Cancer Res 1994 54: 2334-2336. [Abstract] [PDF]  

The Effect of Divalent Nickel (Ni²⁺) on in Vitro DNA Replication by DNA Polymerase

Yue E. Chin, Elizabeth T. Snow, Mitchell D. Cohen, and Nelwyn T. Christie
Cancer Res 1994 54: 2337-2341. [Abstract] [PDF]  

Carcinogenesis:

"Hot Spots" of Chromium Accumulation at Bifurcations of Chromate Workers' Bronchi

Yuichi Ishikawa, Ken Nakagawa, Yukitoshi Satoh, Tomoyuki Kitagawa, Haruo Sugano, Toshio Hirano, and Eiju Tsuchiya
Cancer Res 1994 54: 2342-2346. [Abstract] [PDF]  

Increased Expression of Transforming Growth Factor ß Isoforms and Basic Fibroblast Growth Factor in Complex Hyperplasia and Adenocarcinoma of the Endometrium: Evidence for Paracrine and Autocrine Action

Leslie I. Gold, Babita Saxena, Khush R. Mittal, Michael Marmor, Sunanda Goswami, Lila Nactigal, Murray Korc, and Rita I. Demopoulos
Cancer Res 1994 54: 2347-2358. [Abstract] [PDF]  

Chemoprevention of 4-Nitroquinoline 1-Oxide-induced Oral Carcinogenesis by Dietary Protocatechuic Acid during Initiation and Postinitiation Phases

Takuji Tanaka, Toshihiko Kawamori, Masami Ohnishi, Kiyohisa Okamoto, Hideki Mori, and Akira Hara
Cancer Res 1994 54: 2359-2365. [Abstract] [PDF]  

Clinical Investigations:

Bone Marrow Micrometastases in Chemotherapy-responsive Advanced Breast Cancer: Effect of ex Vivo Purging with 4-Hydroperoxycyclophosphamide

Jose Passos-Coelho, Amy A. Ross, Janice M. Davis, Anne-Marie Huelskamp, Barbara Clarke, Stephen J. Noga, Nancy E. Davidson, and M. John Kennedy
Cancer Res 1994 54: 2366-2371. [Abstract] [PDF]  

Endocrinology:

Urokinase Overproduction Results in Increased Skeletal Metastasis by Prostate Cancer Cells in Vivo

Abderrahim Achbarou, Stephanie Kaiser, Gilles Tremblay, Louis-Georges Ste-Marie, Pnina Brodt, David Goltzman, and Shafaat Ahmed Rabbani
Cancer Res 1994 54: 2372-2377. [Abstract] [PDF]  

Epidemiology:

Familiality of Cancer in Utah

Lisa A. Cannon-Albright, Alun Thomas, David E. Goldgar, Khosrow Gholami, Kerry Rowe, Matt Jacobsen, William P. McWhorter, and Mark H. Skolnick
Cancer Res 1994 54: 2378-2385. [Abstract] [PDF]  

Exposure to Phenoxyacetic Acids, Chlorophenols, or Organic Solvents in Relation to Histopathology, Stage, and Anatomical Localization of Non-Hodgkin's Lymphoma

Lennart Hardell, Mikael Eriksson, and Anna Degerman
Cancer Res 1994 54: 2386-2389. [Abstract] [PDF]  

Intake of Fat, Meat, and Fiber in Relation to Risk of Colon Cancer in Men

Edward Giovannucci, Eric B. Rimm, Meir J. Stampfer, Graham A. Colditz, Alberto Ascherio, and Walter C. Willett
Cancer Res 1994 54: 2390-2397. [Abstract] [PDF]  

Experimental Therapeutics:

Nonenzymatic Reductive Activation of 7-N-{{2-{[2-(-L-Glutamylamino)ethyl] dithio}ethyl}}mitomycin C by Thiol Molecules: a Novel Mitomycin C Derivative Effective on Mitomycin C-resistant Tumor Cells

Jeong-Hyung Lee, Mikihiko Naito, and Takashi Tsuruo
Cancer Res 1994 54: 2398-2403. [Abstract] [PDF]  

Characteristics of Antitumor Activity of KW-2189, a Novel Water-soluble Derivative of Duocarmycin, against Murine and Human Tumors

Eiji Kobayashi, Akihiko Okamoto, Masao Asada, Masami Okabe, Satoru Nagamura, Akira Asai, Hiromitsu Saito, Katsushige Gomi, and Tadashi Hirata
Cancer Res 1994 54: 2404-2410. [Abstract] [PDF]  

Cytotoxicity of Mitomycin C and Adriamycin in Freshly Isolated Rat Hepatocytes: The Role of Cytochrome P450

Arnold R. Goeptar, Ed J. Groot, Heleen Scheerens, Jan N. M. Commandeur, and Nico P. E. Vermeulen
Cancer Res 1994 54: 2411-2418. [Abstract] [PDF]  

Wortmannin, a Potent and Selective Inhibitor of Phosphatidylinositol-3-kinase

Garth Powis, Rosanne Bonjouklian, Margareta M. Berggren, Alfred Gallegos, Robert Abraham, Curtis Ashendel, Leon Zalkow, William F. Matter, Jeffrey Dodge, Gerald Grindey, and Chris J. Vlahos
Cancer Res 1994 54: 2419-2423. [Abstract] [PDF]  

Quercetin Mediates the Down-Regulation of Mutant p53 in the Human Breast Cancer Cell Line MDA-MB468

Matías A. Avila, Juan A. Velasco, José Cansado, and Vicente Notario
Cancer Res 1994 54: 2424-2428. [Abstract] [PDF]  

Hematopoietic Rescue via T-Cell-dependent, Endogenous Granulocyte-Macrophage Colony-stimulating Factor Induced by the Pineal Neurohormone Melatonin in Tumor-bearing Mice

Georges J. M. Maestroni, Valeria Covacci, and A. Conti
Cancer Res 1994 54: 2429-2432. [Abstract] [PDF]  

Immunology:

Induction of IgG Antibodies Directed to a M_r 31,000 Melanoma Antigen in Patients Immunized with Vaccinia Virus Melanoma Oncolysates

Odile Berthier-Vergnes, Jacques Portoukalian, Eleuthère Lefthériotis, and Jean-François Doré
Cancer Res 1994 54: 2433-2439. [Abstract] [PDF]  

Blood Group ABO-related Glycosylation of Urothelial Cell Lines: Immunocytological, Enzymatic, and Genetic Characterization

Peter Meldgaard, Eric H. Holmes, Eric P. Bennett, Henrik Clausen, Jesper Zeuthen, Hans Wolf, and Torben F. Ørntoft
Cancer Res 1994 54: 2440-2447. [Abstract] [PDF]  

Chimeric Murine-Human Antibodies Directed against Folate Binding Receptor Are Efficient Mediators of Ovarian Carcinoma Cell Killing

Leslie R. Coney, Delia Mezzanzanica, David Sanborn, Patrizia Casalini, Maria I. Colnaghi, and Vincent R. Zurawski, Jr.
Cancer Res 1994 54: 2448-2455. [Abstract] [PDF]  

-Interferon Inhibits Fc Receptor II-mediated Phagocytosis of Tumor Cells by Human Macrophages

Karen A. Backman and Paul M. Guyre
Cancer Res 1994 54: 2456-2461. [Abstract] [PDF]  

Activated Murine Macrophages Induce Apoptosis in Tumor Cells through Nitric Oxide-dependent or -independent Mechanisms

Shijun Cui, Jonathan S. Reichner, Romeo B. Mateo, and Jorge E. Albina
Cancer Res 1994 54: 2462-2467. [Abstract] [PDF]  

Molecular Biology and Genetics:

Multiple Subcellular Localization of bcl-2: Detection in Nuclear Outer Membrane, Endoplasmic Reticulum Membrane, and Mitochondrial Membranes

Yukihiro Akao, Yoshinori Otsuki, Seiko Kataoka, Yuko Ito, and Yoshihide Tsujimoto
Cancer Res 1994 54: 2468-2471. [Abstract] [PDF]  

Platelet-derived Growth Factor-induced Expression of Messenger RNA for the Proliferating Cell Nuclear Antigen Requires a Functional Receptor for the Insulin-like Growth Factor I

Masahiko Miura, Shi-Wei Li, Guillaume Dumenil, and Renato Baserga
Cancer Res 1994 54: 2472-2477. [Abstract] [PDF]  

Molecular Analysis of hprt Gene Mutations in Skin Fibroblasts of Rats Exposed in Vivo to N-Methyl-N-nitrosourea or N-Ethyl-N-nitrosourea

Jacob G. Jansen, George R. Mohn, Harry Vrieling, Corrie M.M. van Teijlingen, Paul H.M. Lohman, and Albert A. van Zeeland
Cancer Res 1994 54: 2478-2485. [Abstract] [PDF]  

One-megabase Yeast Artificial Chromosome and 400-kilobase Cosmid-phage Contigs Containing the von Hippel-Lindau Tumor Suppressor and Ca²⁺-transporting Adenosine Triphosphatase Isoform 2 Genes

Igor Kuzmin, Thomas Stackhouse, Farida Latif, Fuh-Mei Duh, Laura Geil, James Gnarra, Masahiro Yao, Mary Lou Orcutt, Hua Li, Kalman Tory, Denis Le Paslier, Ilya Chumakov, Daniel Cohen, A. Craig Chinault, W. Marston Linehan, Michael I. Lerman, and Berton Zbar
Cancer Res 1994 54: 2486-2491. [Abstract] [PDF]  

Tumor Biology:

Identification of the Receptor for a Novel M_r 78,000 "Invasion Stimulating Factor" from Metastatic Human Prostatic PC-3 ML Clones

M. Wang, M. Stearns, and M. E. Stearns
Cancer Res 1994 54: 2492-2495. [Abstract] [PDF]  

Relationship of p53 Overexpression and Up-Regulation of Proliferating Cell Nuclear Antigen with the Clinical Course of Non-Small Cell Lung Cancer

Masahito Ebina, Seth M. Steinberg, James L. Mulshine, and R. Ilona Linnoila
Cancer Res 1994 54: 2496-2503. [Abstract] [PDF]  

Increased Methotrexate Resistance and dhfr Gene Amplification as a Consequence of Induced Ha-ras Expression in NIH 3T3 Cells

Maqsood A. Wani, Xin Xu, and Peter J. Stambrook
Cancer Res 1994 54: 2504-2508. [Abstract] [PDF]  

Extracts of Porcine Pancreas Prevent Progression of Hypercalcemia and Cachexia and Prolong Survival in Nude Mice Bearing a Human Squamous Carcinoma

Toshiyuki Yoneda, Yoshito Takaoka, Brendan F. Boyce, Laura Scott, and Gregory R. Mundy
Cancer Res 1994 54: 2509-2513. [Abstract] [PDF]  

Isolation and Functional Characterization of the A32 Melanoma-associated Antigen

Ie-Ming Shih, David E. Elder, David Speicher, Judith P. Johnson, and Meenhard Herlyn
Cancer Res 1994 54: 2514-2520. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1994 54: 2521-2523. [PDF]  

Erratum

Cancer Res 1994 54: 2523-2524. [PDF]  

Announcements:

Recent Death

Cancer Res 1994 54: 2522 [PDF]  

Calendar of Events

Cancer Res 1994 54: 2522-2523. [PDF]  

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