Advances in Brief:

Loss of Expression of the p16/Cyclin-dependent Kinase Inhibitor 2 Tumor Suppressor Gene in Melanocytic Lesions Correlates with Invasive Stage of Tumor Progression

Jon A. Reed, Frank Loganzo, Jr., Christopher R. Shea, Graeme J. Walker, Jose F. Flores, J. Michael Glendening, Jennifer K. Bogdany, Monica J. Shiel, Frank G. Haluska, Jane W. Fountain, and Anthony P. Albino
Cancer Res 1995 55: 2713-2718. [Abstract] [PDF]  

Evidence against Dominant Negative Mechanisms of Intestinal Polyp Formation by Apc Gene Mutations

Masanobu Oshima, Hiroko Oshima, Masahiko Kobayashi, Masahiro Tsutsumi, and Makoto M. Taketo
Cancer Res 1995 55: 2719-2722. [Abstract] [PDF]  

Transcriptional Activation of the Proto-oncogene c-jun by Asbestos and H₂O₂ Is Directly Related to Increased Proliferation and Transformation of Tracheal Epithelial Cells

Cynthia R. Timblin, Yvonne W. M. Janssen, and Brooke T. Mossman
Cancer Res 1995 55: 2723-2726. [Abstract] [PDF]  

A Variant Glucocorticoid Receptor Messenger RNA Is Expressed in Multiple Myeloma Patients

Nancy L. Krett, Shafali Pillay, Pamela A. Moalli, Philip R. Greipp, and Steven T. Rosen
Cancer Res 1995 55: 2727-2729. [Abstract] [PDF]  

Expression of B7-1 by Highly Metastatic Mouse T Lymphomas Induces Optimal Natural Killer Cell-mediated Cytotoxicity

Anja B. Geldhof, Geert Raes, Marleen Bakkus, Sophie Devos, Kris Thielemans, and Patrick De Baetselier
Cancer Res 1995 55: 2730-2733. [Abstract] [PDF]  

Telomerase Activity in Human Liver Tissues: Comparison between Chronic Liver Disease and Hepatocellular Carcinomas

Hidetoshi Tahara, Toshio Nakanishi, Mikiya Kitamoto, Ryo Nakashio, Jerry W. Shay, Eiichi Tahara, Goro Kajiyama, and Toshinori Ide
Cancer Res 1995 55: 2734-2736. [Abstract] [PDF]  

Mch2, a New Member of the Apoptotic Ced-3/Ice Cysteine Protease Gene Family

Teresa Fernandes-Alnemri, Gerald Litwack, and Emad S. Alnemri
Cancer Res 1995 55: 2737-2742. [Abstract] [PDF]  

Ovarian Carcinoma-associated TaqI Restriction Fragment Length Polymorphism in Intron G of the Progesterone Receptor Gene Is Due to an Alu Sequence Insertion

Susan M. Rowe, Sorcha J. Coughlan, Neil J. McKenna, Elaine Garrett, Dirk G. Kieback, Desmond N. Carney, and Denis R. Headon
Cancer Res 1995 55: 2743-2745. [Abstract] [PDF]  

Loss of Wild-Type p53 Bestows a Growth Advantage on Primary Cortical Astrocytes and Facilitates Their in Vitro Transformation

Oliver Bögler, H-J. Su Huang, and Webster K. Cavenee
Cancer Res 1995 55: 2746-2751. [Abstract] [PDF]  

Overexpression of the Focal Adhesion Kinase (p125^FAK) in Invasive Human Tumors

Lewis V. Owens, LiHui Xu, Rolf J. Craven, Georgette A. Dent, Tim M. Weiner, Lori Kornberg, Edison T. Liu, and William G. Cance
Cancer Res 1995 55: 2752-2755. [Abstract] [PDF]  

Mutations of p16^Ink4/CDKN2 and p15^Ink4B/MTS2 Genes in Biliary Tract Cancers

Sadao Yoshida, Takeshi Todoroki, Yoshihito Ichikawa, Shuji Hanai, Hiromichi Suzuki, Mitsuo Hori, Katashi Fukao, Masanao Miwa, and Kazuhiko Uchida
Cancer Res 1995 55: 2756-2760. [Abstract] [PDF]  

Special Lecture:

Initiatives with Platinum- and Quinazoline-based Antitumor Molecules—Fourteenth Bruce F. Cain Memorial Award Lecture

Ken R. Harrap
Cancer Res 1995 55: 2761-2768. [Abstract] [PDF]  

Carcinogenesis:

Mucosa-preferential DNA Adduct Formation by 2-Amino-3-methylimidazo-[4,5-f]quinoline in the Rat Colonic Wall

Aiichiro Kajikawa, Atsushi Umemoto, Kunimi Hamada, Masaki Tanaka, Takemi Kinouchi, Yoshinari Ohnishi, and Yasumasa Monden
Cancer Res 1995 55: 2769-2773. [Abstract] [PDF]  

Mouse Skin Tumor Progression Results in Differential Expression of Retinoic Acid and Retinoid X Receptors

Nadine Darwiche, Giulia Celli, Tamar Tennenbaum, Adam B. Glick, Stuart H. Yuspa, and Luigi M. De Luca
Cancer Res 1995 55: 2774-2782. [Abstract] [PDF]  

Clinical Investigations:

G_M2-KLH Conjugate Vaccine: Increased Immunogenicity in Melanoma Patients after Administration with Immunological Adjuvant QS-21

Friedhelm Helling, Shengle Zhang, Ann Shang, Sucharita Adluri, Michele Calves, Rao Koganty, B. Michael Longenecker, Tzy-J. Yao, Herbert F. Oettgen, and Philip O. Livingston
Cancer Res 1995 55: 2783-2788. [Abstract] [PDF]  

Glutathione S-Transferase Activity and Glutathione S-Transferase µ Expression in Subjects with Risk for Colorectal Cancer

Christine E. Szarka, Gordon R. Pfeiffer, Susan T. Hum, Lynette C. Everley, Andrew M. Balshem, Dirk F. Moore, Samuel Litwin, Eric B. Goosenberg, Harold Frucht, Paul F. Engstrom, and Margie L. Clapper
Cancer Res 1995 55: 2789-2793. [Abstract] [PDF]  

Experimental Therapeutics:

Tyrphostin AG17, [(3,5-Di-tert-butyl-4-hydroxybenzylidene)-malononitrile], Inhibits Cell Growth by Disrupting Mitochondria

Angelika M. Burger, Gurmeet Kaur, Michael C. Alley, Jeffrey G. Supko, Louis Malspeis, Michael R. Grever, and Edward A. Sausville
Cancer Res 1995 55: 2794-2799. [Abstract] [PDF]  

The Interaction of Hydroxyurea and Iododeoxyuridine on the Radiosensitivity of Human Bladder Cancer Cells

Mei-Ling Kuo, Keith A. Kunugi, Mary J. Lindstrom, and Timothy J. Kinsella
Cancer Res 1995 55: 2800-2805. [Abstract] [PDF]  

Antitumor Activities of a New Indolocarbazole Substance, NB-506, and Establishment of NB-506-resistant Cell Lines, SBC-3/NB

Fumihiko Kanzawa, Kazuto Nishio, Naohiro Kubota, and Nagahiro Saijo
Cancer Res 1995 55: 2806-2813. [Abstract] [PDF]  

Mechanism of Action of the Antineoplastic Drug Lonidamine: ³¹P and ¹³C Nuclear Magnetic Resonance Studies

Hava Ben-Horin, Maria Tassini, Antonio Vivi, Gil Navon, and Ofer Kaplan
Cancer Res 1995 55: 2814-2821. [Abstract] [PDF]  

20-epi-Vitamin D₃ Analogues: A Novel Class of Potent Inhibitors of Proliferation and Inducers of Differentiation of Human Breast Cancer Cell Lines

Elena Elstner, Marjane Linker-Israeli, Johnathan Said, Tehila Umiel, Sven de Vos, I. Peter Shintaku, David Heber, Lise Binderup, Milan Uskokovic, and H. Phillip Koeffler
Cancer Res 1995 55: 2822-2830. [Abstract] [PDF]  

Application of a Tumor Suppressor (C-CAM1)-expressing Recombinant Adenovirus in Androgen-independent Human Prostate Cancer Therapy: A Preclinical Study

David I. Kleinerman, Wei-Wei Zhang, Sue-Hwa Lin, Nguyen T. Van, Andrew C. von Eschenbach, and Jer-Tsong Hsieh
Cancer Res 1995 55: 2831-2836. [Abstract] [PDF]  

Effect of the Chemoprotective Agent WR-2721 on Disposition and Biotransformations of Ormaplatin in the Fischer 344 Rat Bearing a Fibrosarcoma

D. Charles Thompson, Steven D. Wyrick, David J. Holbrook, and Stephen G. Chaney
Cancer Res 1995 55: 2837-2846. [Abstract] [PDF]  

Metabolism and Actions of 2-Chloro-9-(2-deoxy-2-fluoro-ß-D-arabinofuranosyl)-adenine in Human Lymphoblastoid Cells

Chunxi Xie and William Plunkett
Cancer Res 1995 55: 2847-2852. [Abstract] [PDF]  

Activity of Temozolomide in the Treatment of Central Nervous System Tumor Xenografts

Henry S. Friedman, M. Eileen Dolan, Anthony E. Pegg, Susan Marcelli, Stephen Keir, Joseph J. Catino, Darell D. Bigner, and S. Clifford Schold, Jr.
Cancer Res 1995 55: 2853-2857. [Abstract] [PDF]  

Immunology:

Improved Tumor Radioimmunodetection Using a Single-Chain Fv and -Interferon: Potential Clinical Applications for Radioimmunoguided Surgery and Scanning

Carol A. Nieroda, Diane E. Milenic, Jorge A. Carrasquillo, Jeffrey Schlom, and John W. Greiner
Cancer Res 1995 55: 2858-2865. [Abstract] [PDF]  

Molecular Biology and Genetics:

Somatic Mutations Detected by Mini- and Microsatellite DNA Markers Reveal Clonal Intratumor Heterogeneity in Gastrointestinal Cancers

Susanne Nagel, Bettina Borisch, Swee Lay Thein, Madeleine Oestreicher, Fritz Nöthiger, Stefan Birrer, Andreas Tobler, and Martin F. Fey
Cancer Res 1995 55: 2866-2870. [Abstract] [PDF]  

Loss of Heterozygosity of Tumor Suppressor Genes in Testis Cancer

Hong-Qi Peng, Denis Bailey, David Bronson, Paul E. Goss, and David Hogg
Cancer Res 1995 55: 2871-2875. [Abstract] [PDF]  

Frequent Detection of bcl-2/J_H Translocations in Human Blood and Organ Samples by a Quantitative Polymerase Chain Reaction Assay

Weizhen Ji, Guang-zhi Qu, Peng Ye, Xian-Yang Zhang, Susan Halabi, and Melanie Ehrlich
Cancer Res 1995 55: 2876-2882. [Abstract] [PDF]  

Expression of a Deletion Mutant of the E2F1 Transcription Factor in Fibroblasts Lengthens S Phase and Increases Sensitivity to S Phase-specific Toxins

Thomas J. Logan, Devon L. Evans, W. Edward Mercer, Mary-Ann Bjornsti, and David J. Hall
Cancer Res 1995 55: 2883-2891. [Abstract] [PDF]  

Chromosome 9p Allelic Loss and p16/CDKN2 in Breast Cancer and Evidence of p16 Inactivation in Immortal Breast Epithelial Cells

Andrew J. Brenner and C. Marcelo Aldaz
Cancer Res 1995 55: 2892-2895. [Abstract] [PDF]  

A Screening Method to Identify Genes Commonly Overexpressed in Carcinomas and the Identification of a Novel Complementary DNA Sequence

Jennifer A. Byrne, Catherine Tomasetto, Jean-Marie Garnier, Nicolas Rouyer, Marie-Geneviève Mattei, Jean-Pierre Bellocq, Marie-Christine Rio, and Paul Basset
Cancer Res 1995 55: 2896-2903. [Abstract] [PDF]  

Seven Megabase Yeast Artificial Chromosome Contig at Region 11p15: Identification of a Yeast Artificial Chromosome Spanning the Breakpoint of a Chromosomal Translocation Found in a Case of Beckwith-Wiedemann Syndrome

Massimo Negrini, Silvia Sabbioni, Masataka Ohta, Maria Luisa Veronese, Shashi Rattan, Claudine Junien, and Carlo M. Croce
Cancer Res 1995 55: 2904-2909. [Abstract] [PDF]  

Topological Control of p21^WAF1/CIP1 Expression in Normal and Neoplastic Tissues

Wafik S. El-Deiry, Takashi Tokino, Todd Waldman, Jon D. Oliner, Victor E. Velculescu, Marilee Burrell, David E. Hill, Eugene Healy, Jonathan L. Rees, Stanley R. Hamilton, Kenneth W. Kinzler, and Bert Vogelstein
Cancer Res 1995 55: 2910-2919. [Abstract] [PDF]  

Tumor Biology:

The -Glucosidase I Inhibitor Castanospermine Alters Endothelial Cell Glycosylation, Prevents Angiogenesis, and Inhibits Tumor Growth

Roberto Pili, Joan Chang, Richard A. Partis, Richard A. Mueller, Francis J. Chrest, and Antonino Passaniti
Cancer Res 1995 55: 2920-2926. [Abstract] [PDF]  

Cyclic AMP-regulated Synthesis of the Tissue Inhibitors of Metalloproteinases Suppresses the Invasive Potential of the Human Fibrosarcoma Cell Line HT1080

Kazuhiro Tanaka, Yukihide Iwamoto, Yasumasa Ito, Toru Ishibashi, Yusaku Nakabeppu, Mutsuo Sekiguchi, and Yoichi Sugioka
Cancer Res 1995 55: 2927-2935. [Abstract] [PDF]  

Fas/APO-1 Gene Transfer for Human Malignant Glioma

Michael Weller, Ursula Malipiero, Anne Rensing-Ehl, Philip J. Barr, and Adriano Fontana
Cancer Res 1995 55: 2936-2944. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1995 55: 2945-2947. [PDF]  

Employment Register of the American Association for Cancer Research

Cancer Res 1995 55: 2948-2957. [PDF]  

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