Advances in Brief:

Allelic Loss on Chromosome 8p12–21 in Microdissected Prostatic Intraepithelial Neoplasia

Michael R. Emmert-Buck, Cathy D. Vocke, Rudy O. Pozzatti, Paul H. Duray, Scott B. Jennings, Charles D. Florence, Zhengping Zhuang, David G. Bostwick, Lance A. Liotta, and W. Marston Linehan
Cancer Res 1995 55: 2959-2962. [Abstract] [PDF]  

Cell- and Region-specific Expression of Biliary Glycoprotein and Its Messenger RNA in Normal Human Colonic Mucosa

Lars Frängsmyr, Vladimir Baranov, Friedrich Prall, Moorix Mo-Wai Yeung, Christoph Wagener, and Sten Hammarström
Cancer Res 1995 55: 2963-2967. [Abstract] [PDF]  

Codeletion of p15 and p16 Genes in Primary Non-Small Cell Lung Carcinoma

Sheng Xiao, Daizong Li, Joseph M. Corson, Jan Vijg, and Jonathan A. Fletcher
Cancer Res 1995 55: 2968-2971. [Abstract] [PDF]  

APC Binds to the Novel Protein EB1

Li-Kuo Su, Marilee Burrell, David E. Hill, Jenö Gyuris, Roger Brent, Rodney Wiltshire, Jeff Trent, Bert Vogelstein, and Kenneth W. Kinzler
Cancer Res 1995 55: 2972-2977. [Abstract] [PDF]  

Phosphoinositide Signaling in Nuclei of Friend Cells: Tiazofurin Down-Regulates Phospholipase C ß₁

Lucia Manzoli, Anna Maria Billi, R. Stewart Gilmour, Alberto Maria Martelli, Alessandro Matteucci, Silvia Rubbini, George Weber, and Lucio Cocco
Cancer Res 1995 55: 2978-2980. [Abstract] [PDF]  

Inherited GSTM1 and NAT2 Defects as Concurrent Risk Modifiers in Asbestos-related Human Malignant Mesothelioma

Ari Hirvonen, Katarina Pelin, Lauri Tammilehto, Antti Karjalainen, Karin Mattson, and Kaija Linnainmaa
Cancer Res 1995 55: 2981-2983. [Abstract] [PDF]  

CD4⁺ T-Cell Immunity to Mutated ras Protein in Pancreatic and Colon Cancer Patients

Huilian Qin, Wei Chen, Masazumi Takahashi, Mary L. Disis, David R. Byrd, Larry McCahill, Kenneth A. Bertram, Robert G. Fenton, David J. Peace, and Martin A. Cheever
Cancer Res 1995 55: 2984-2987. [Abstract] [PDF]  

Complex Structure and Regulation of the P16 (MTS1) Locus

Steven Stone, Ping Jiang, Priya Dayananth, Sean V. Tavtigian, Harold Katcher, David Parry, Gordon Peters, and Alexander Kamb
Cancer Res 1995 55: 2988-2994. [Abstract] [PDF]  

A Novel p16^INK4A Transcript

Li Mao, Adrian Merlo, Gauri Bedi, Geoffrey I. Shapiro, Christian D. Edwards, Barrett J. Rollins, and David Sidransky
Cancer Res 1995 55: 2995-2997. [Abstract] [PDF]  

Mutation Analysis of the BRCA1 Gene in Ovarian Cancers

Hiroyuki Takahashi, Kian Behbakht, Patricia E. McGovern, Hsiu-Chiang Chiu, Fergus J. Couch, Barbara L. Weber, Lori S. Friedman, Mary-Claire King, Masakuni Furusato, Virginia A. LiVolsi, Andrew W. Menzin, Paul C. Liu, Ivor Benjamin, Mark A. Morgan, Stephanie A. King, Beth Ann Rebane, Annmarie Cardonick, John J. Mikuta, Stephen C. Rubin, and Jeff Boyd
Cancer Res 1995 55: 2998-3002. [Abstract] [PDF]  

Definition and Refinement of Chromosome 11 Regions of Loss of Heterozygosity in Breast Cancer: Identification of a New Region at 11q23.3

Massimo Negrini, Debora Rasio, Garrett M. Hampton, Silvia Sabbioni, Shashi Rattan, Stephen L. Carter, Anne L. Rosenberg, Gordon F. Schwartz, Yosef Shiloh, Webster K. Cavenee, and Carlo M. Croce
Cancer Res 1995 55: 3003-3007. [Abstract] [PDF]  

Anticancer Activity of ß-L-Dioxolane-cytidine, a Novel Nucleoside Analogue with the Unnatural L Configuration

Kristie L. Grove, Xin Guo, Shwu-Huey Liu, Zhiling Gao, Chung K. Chu, and Yung-Chi Cheng
Cancer Res 1995 55: 3008-3011. [Abstract] [PDF]  

Activation of the Tamoxifen Derivative Metabolite E to Form DNA Adducts: Comparison with the Adducts Formed by Microsomal Activation of Tamoxifen

Krisztina Pongracz, Deena N. Pathak, Takemichi Nakamura, Alma L. Burlingame, and William J. Bodell
Cancer Res 1995 55: 3012-3015. [Abstract] [PDF]  

Biochemistry and Biophysics:

Enhanced Expression of Calreticulin in the Nucleus of Radioresistant Squamous Carcinoma Cells in Response to Ionizing Radiation

Priya Ramsamooj, Vicente Notario, and Anatoly Dritschilo
Cancer Res 1995 55: 3016-3021. [Abstract] [PDF]  

Synthesis and Pharmacological Characterization of 4-[¹²⁵I]-N-(N-Benzylpiperidin-4-yl)-4-iodobenzamide: A High Affinity Receptor Ligand for Potential Imaging of Breast Cancer

Christy S. John, Bertold J. Vilner, Mary E. Gulden, Simon M. N. Efange, Rosemary B. Langason, Terry W. Moody, and Wayne D. Bowen
Cancer Res 1995 55: 3022-3027. [Abstract] [PDF]  

Impairment of the Mitochondrial Respiratory Chain Activity in Diethylnitrosamine-induced Rat Hepatomas: Possible Involvement of Oxygen Free Radicals

Eric Boitier, Mansouria Merad-Boudia, Christiane Guguen-Guillouzo, Nicole Defer, Irène Ceballos-Picot, Jean-Paul Leroux, and Cécile Marsac
Cancer Res 1995 55: 3028-3035. [Abstract] [PDF]  

Disposition and Metabolism of the Angiogenic Moderator O-(Chloroacetyl-carbamoyl) Fumagillol (TNP-470; AGM-1470) in Human Hepatocytes and Tissue Microsomes

Laurent Placidi, Erika Cretton-Scott, Georges de Sousa, Roger Rahmani, Michel Placidi, and Jean-Pierre Sommadossi
Cancer Res 1995 55: 3036-3042. [Abstract] [PDF]  

Carcinogenesis:

DNA Adducts of 2-Amino-3-methylimidazo[4,5-f]quinoline (IQ) in Colon, Bladder, and Kidney of Congenic Mice Differing in Ah Responsiveness and N-Acetyltransferase Genotype

Pratibha V. Nerurkar, Herman A. J. Schut, Lucy M. Anderson, Charles W. Riggs, Elizabeth G. Snyderwine, Snorri S. Thorgeirsson, Wendell W. Weber, Jerry M. Rice, and Gerald N. Levy
Cancer Res 1995 55: 3043-3049. [Abstract] [PDF]  

1,25-Dihydroxy-16-ene-23-yne-26,27-hexafluorocholecalciferol, a Noncalcemic Analogue of 1,25-Dihydroxyvitamin D₃, Inhibits Azoxymethane-induced Colonic Tumorigenesis

Ramesh K. Wali, Marc Bissonnette, Sharad Khare, John Hart, Michael D. Sitrin, and Thomas A. Brasitus
Cancer Res 1995 55: 3050-3054. [Abstract] [PDF]  

Frequent Novel DNA Copy Number Increase in Squamous Cell Head and Neck Tumors

Pius M. Brzoska, Nikki A. Levin, Karen K. Fu, Michael J. Kaplan, Mark I. Singer, Joe W. Gray, and Michael F. Christman
Cancer Res 1995 55: 3055-3059. [Abstract] [PDF]  

Clinical Investigations:

Phase I Clinical and Pharmacological Study of Suppression of Human Antimouse Antibody Response to Monoclonal Antibody L6 by Deoxyspergualin

Kapil Dhingra, Herbert Fritsche, James L. Murray, Albert F. LoBuglio, M. B. Khazaeli, Susan Kelley, Mark A. Tepper, Dennis Grasela, Aman Buzdar, Vicente Valero, Daniel Booser, Hannah Whealin, Tedd J. Collins, Janice M. Pursley, and Gabriel Hortobagyi
Cancer Res 1995 55: 3060-3067. [Abstract] [PDF]  

Endocrinology:

Distant Metastases from Prostatic Carcinoma Express Androgen Receptor Protein

Alfred Hobisch, Zoran Culig, Christian Radmayr, Georg Bartsch, Helmut Klocker, and Anton Hittmair
Cancer Res 1995 55: 3068-3072. [Abstract] [PDF]  

Effect of Aromatase Inhibitors on Growth of Mammary Tumors in a Nude Mouse Model

Wei Yue, Jiping Wang, Alexei Savinov, and Angela Brodie
Cancer Res 1995 55: 3073-3077. [Abstract] [PDF]  

Experimental Therapeutics:

Lack of Reciprocity in Drug and Light Dose Dependence of Photodynamic Therapy of Pancreatic Adenocarcinoma in Vitro

K. Thomas Moesta, William R. Greco, Stephen O. Nurse-Finlay, John C. Parsons, and Thomas S. Mang
Cancer Res 1995 55: 3078-3084. [Abstract] [PDF]  

LU103793 (NSC D-669356): A Synthetic Peptide That Interacts with Microtubules and Inhibits Mitosis

Monika de Arruda, Celia A. Cocchiaro, Christine M. Nelson, Christine M. Grinnell, Bernd Janssen, Andreas Haupt, and Teresa Barlozzari
Cancer Res 1995 55: 3085-3092. [Abstract] [PDF]  

Induction of Apoptosis by 5-Azacytidine: Drug Concentration-dependent Differences in Cell Cycle Specificity

Tomoyuki Murakami, Xun Li, Jianping Gong, Umesh Bhatia, Frank Traganos, and Zbigniew Darzynkiewicz
Cancer Res 1995 55: 3093-3098. [Abstract] [PDF]  

Activity of a Single-Chain Immunotoxin That Selectively Kills Lymphoma and Other B-Lineage Cells Expressing the CD40 Antigen

Joseph A. Francisco, Lisa K. Gilliland, Mark R. Stebbins, Nancy A. Norris, Jeffrey A. Ledbetter, and Clay B. Siegall
Cancer Res 1995 55: 3099-3104. [Abstract] [PDF]  

Gene Therapy for Hepatoma Cells Using a Retrovirus Vector Carrying Herpes Simplex Virus Thymidine Kinase Gene under the Control of Human -Fetoprotein Gene Promoter

Akio Ido, Keisuke Nakata, Yuji Kato, Kazuhiko Nakao, Ken Murata, Masatoshi Fujita, Nobuko Ishii, Taiki Tamaoki, Hiroshi Shiku, and Shigenobu Nagataki
Cancer Res 1995 55: 3105-3109. [Abstract] [PDF]  

Antineoplastic Drugs Sulindac Sulfide and Sulfone Inhibit Cell Growth by Inducing Apoptosis

Gary A. Piazza, Alanna L. Kulchak Rahm, Mary Krutzsch, Gerhard Sperl, Nancy Shipp Paranka, Paul H. Gross, Klaus Brendel, Randall W. Burt, David S. Alberts, Rifat Pamukcu, and Dennis J. Ahnen
Cancer Res 1995 55: 3110-3116. [Abstract] [PDF]  

Apoptosis Induction Mediated by Wild-Type p53 Adenoviral Gene Transfer in Squamous Cell Carcinoma of the Head and Neck

Ta-Jen Liu, Adel K. El-Naggar, Timothy J. McDonnell, Kim D. Steck, Mary Wang, Dorothy L. Taylor, and Gary L. Clayman
Cancer Res 1995 55: 3117-3122. [Abstract] [PDF]  

Immunology:

Direct Correlation between Expression of Endogenous Inducible Nitric Oxide Synthase and Regression of M5076 Reticulum Cell Sarcoma Hepatic Metastases in Mice Treated with Liposomes Containing Lipopeptide CGP 31362

Keping Xie, Suyun Huang, Zhongyun Dong, Mordechai Gutman, and Isaiah J. Fidler
Cancer Res 1995 55: 3123-3131. [Abstract] [PDF]  

Effects of Radiolabeling Monoclonal Antibodies with a Residualizing Iodine Radiolabel on the Accretion of Radioisotope in Tumors

Rhona Stein, David M. Goldenberg, Suzanne R. Thorpe, Amartya Basu, and M. Jules Mattes
Cancer Res 1995 55: 3132-3139. [Abstract] [PDF]  

Monoclonal Antibodies against EGFRvIII Are Tumor Specific and React with Breast and Lung Carcinomas and Malignant Gliomas

Carol J. Wikstrand, Laura P. Hale, Surinder K. Batra, M. Leslie Hill, Peter A. Humphrey, Shekar N. Kurpad, Roger E. McLendon, David Moscatello, Charles N. Pegram, Craig J. Reist, S. Thomas Traweek, Albert J. Wong, Michael R. Zalutsky, and Darell D. Bigner
Cancer Res 1995 55: 3140-3148. [Abstract] [PDF]  

Quantitative Correlation between HLA Class I Allele Expression and Recognition of Melanoma Cells by Antigen-specific Cytotoxic T Lymphocytes

Licia Rivoltini, Kathleen C. Barracchini, Vincenzo Viggiano, Yutaka Kawakami, Andrew Smith, Arnold Mixon, Nicholas P. Restifo, Suzanne L. Topalian, Toni B. Simonis, Steven A. Rosenberg, and Francesco M. Marincola
Cancer Res 1995 55: 3149-3157. [Abstract] [PDF]  

Molecular Biology and Genetics:

Interferon -2b and Retinoic Acid Combined Treatment Affects Proliferation and Gene Expression of Human Cervical Carcinoma Cells

Francesca Lancillotti, Valeria Giandomenico, Elisabetta Affabris, Gianna Fiorucci, Giovanna Romeo, and Giovanni Battista Rossi
Cancer Res 1995 55: 3158-3164. [Abstract] [PDF]  

Somatic Mutations of the Adenomatous Polyposis Coli Gene in Gastroduodenal Tumors from Patients with Familial Adenomatous Polyposis

Masahiro Toyooka, Motoko Konishi, Rei Kikuchi-Yanoshita, Takeo Iwama, and Michiko Miyaki
Cancer Res 1995 55: 3165-3170. [Abstract] [PDF]  

Genetic Alterations Cooperate with v-Ha-ras to Accelerate Multistage Carcinogenesis in TG.AC Transgenic Mouse Skin

David M. Owens, Judson W. Spalding, Raymond W. Tennant, and Robert C. Smart
Cancer Res 1995 55: 3171-3178. [Abstract] [PDF]  

A Gene for Susceptibility to Small Intestinal Cancer, ssic1, Maps to the Distal Part of Mouse Chromosome 4

Remond J. A. Fijneman and Peter Demant
Cancer Res 1995 55: 3179-3182. [Abstract] [PDF]  

Tumor Biology:

Retinoid-induced Suppression of Squamous Cell Differentiation in Human Oral Squamous Cell Carcinoma Xenografts (Line 1483) in Athymic Nude Mice

D. R. Shalinsky, E. D. Bischoff, M. L. Gregory, M. M. Gottardis, J. S. Hayes, W. W. Lamph, R. A. Heyman, M. A. Shirley, T. A. Cooke, P. J. A. Davies, and V. Thomazy
Cancer Res 1995 55: 3183-3191. [Abstract] [PDF]  

Establishment and Molecular Characterization of a Novel Leukemic Cell Line with Philadelphia Chromosome Expressing p230 BCR/ABL Fusion Protein

Hiroshi Wada, Shuki Mizutani, Junji Nishimura, Yuko Usuki, Masatoshi Kohsaki, Masumi Komai, Hideo Kaneko, Shunji Sakamoto, Domenico Delia, Akihisa Kanamaru, and Eizo Kakishita
Cancer Res 1995 55: 3192-3196. [Abstract] [PDF]  

Androgen Up-Regulates Epidermal Growth Factor Receptor Expression and Binding Affinity in PC3 Cell Lines Expressing the Human Androgen Receptor

Abraham L. Brass, John Barnard, Barbara L. Patai, Debra Salvi, and Daniel B. Rukstalis
Cancer Res 1995 55: 3197-3203. [Abstract] [PDF]  

Nonrandom Chromosome Abnormalities in Short-Term Cultured Primary Squamous Cell Carcinomas of the Head and Neck

Yuesheng Jin, Fredrik Mertens, Charlotte Jin, Jan Åkervall, Johan Wennerberg, Ludmila Gorunova, Nils Mandahl, Sverre Heim, and Felix Mitelman
Cancer Res 1995 55: 3204-3210. [Abstract] [PDF]  

Virology:

Impairment of Moloney Murine Leukemia Virus Integration in a Cell Line Underexpressing DNA Topoisomerase II

Pascale Bouillé, Frédéric Subra, Hélène Goulaouic, Sandrine Carteau, and Christian Auclair
Cancer Res 1995 55: 3211-3217. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1995 55: 3218-3220. [PDF]  

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