Advances in Brief:

Chemoprevention of Spontaneous Tumorigenesis in p53-Knockout Mice

Stephen D. Hursting, Susan N. Perkins, Diana C. Haines, Jerrold M. Ward, and James M. Phang
Cancer Res 1995 55: 3949-3953. [Abstract] [PDF]  

Direct Visualization of the Clonal Progression of Primary Cutaneous Melanoma: Application of Tissue Microdissection and Comparative Genomic Hybridization

Rodney N. Wiltshire, Paul Duray, Michael L. Bittner, Tapio Visakorpi, Paul S. Meltzer, Ralph J. Tuthill, Lance A. Liotta, and Jeffrey M. Trent
Cancer Res 1995 55: 3954-3957. [Abstract] [PDF]  

Primary Tumor and Metastasis in Ovarian Cancer Differ in Their Content of Urokinase-type Plasminogen Activator, Its Receptor, and Inhibitors Types 1 and 2

B. Schmalfeldt, W. Kuhn, U. Reuning, L. Pache, P. Dettmar, M. Schmitt, F. Jänicke, H. Höfler, and H. Graeff
Cancer Res 1995 55: 3958-3963. [Abstract] [PDF]  

Expression of Vascular Endothelial Growth Factor and Its Receptor, KDR, Correlates with Vascularity, Metastasis, and Proliferation of Human Colon Cancer

Yutaka Takahashi, Yasuhiko Kitadai, Corazon D. Bucana, Karen R. Cleary, and Lee M. Ellis
Cancer Res 1995 55: 3964-3968. [Abstract] [PDF]  

The Nuclear Tyrosine Kinase Rak Associates with the Retinoblastoma Protein pRb

Rolf J. Craven, William G. Cance, and Edison T. Liu
Cancer Res 1995 55: 3969-3972. [Abstract] [PDF]  

Genetic Variability of the Human SRD5A2 Gene: Implications for Prostate Cancer Risk

Juergen K. V. Reichardt, Nick Makridakis, Brian E. Henderson, Mimi C. Yu, Malcolm C. Pike, and Ronald K. Ross
Cancer Res 1995 55: 3973-3975. [Abstract] [PDF]  

Comparative Allelotype of in Situ and Invasive Human Breast Cancer: High Frequency of Microsatellite Instability in Lobular Breast Carcinomas

C. Marcelo Aldaz, Taiping Chen, Aysegul Sahin, Joan Cunningham, and Melissa Bondy
Cancer Res 1995 55: 3976-3981. [Abstract] [PDF]  

Missense Mutations of the Transforming Growth Factor ß Type II Receptor in Human Head and Neck Squamous Carcinoma Cells

Laure Garrigue-Antar, Teresita Muñoz-Antonia, Scott J. Antonia, Joan Gesmonde, Vincent F. Vellucci, and Michael Reiss
Cancer Res 1995 55: 3982-3987. [Abstract] [PDF]  

Loss of Heterozygosity at Chromosome 11q in Lung Adenocarcinoma: Identification of Three Independent Regions

Debora Rasio, Massimo Negrini, Giacomo Manenti, Tommaso A. Dragani, and Carlo M. Croce
Cancer Res 1995 55: 3988-3991. [Abstract] [PDF]  

The cdc2-related Kinase, PISSLRE, Is Essential for Cell Growth and Acts in G₂ Phase of the Cell Cycle

Shu Li, Timothy K. MacLachlan, Antonio De Luca, Pier Paolo Claudio, Gianluigi Condorelli, and Antonio Giordano
Cancer Res 1995 55: 3992-3995. [Abstract] [PDF]  

A Hereditary Genetic Marker Closely Associated with Microsatellite Instability in Lung Cancer

David Ryberg, Bjørn Arne Lindstedt, Shanbeh Zienolddiny, and Aage Haugen
Cancer Res 1995 55: 3996-3999. [Abstract] [PDF]  

Association of the DF3/MUC1 Breast Cancer Antigen with Grb2 and the Sos/Ras Exchange Protein

Pramod Pandey, Surender Kharbanda, and Donald Kufe
Cancer Res 1995 55: 4000-4003. [Abstract] [PDF]  

Cross-Resistance to Camptothecin Analogues in a Mitoxantrone-resistant Human Breast Carcinoma Cell Line Is Not Due to DNA Topoisomerase I Alterations

Chih-Hsin J. Yang, Julie K. Horton, Kenneth H. Cowan, and Erasmus Schneider
Cancer Res 1995 55: 4004-4009. [Abstract] [PDF]  

Expression of the p16 and p15 Cyclin-dependent Kinase Inhibitors in Lymphocyte Activation and Neuronal Differentiation

Augusto F. Lois, Leslie T. Cooper, Yu Geng, Tsutomu Nobori, and Dennis Carson
Cancer Res 1995 55: 4010-4013. [Abstract] [PDF]  

Perspectives in Cancer Research:

Sunlight—Can It Prevent as well as Cause Cancer?

George P. Studzinski and Dorothy C. Moore
Cancer Res 1995 55: 4014-4022. [Abstract] [PDF]  

Special Lecture:

Genetic Suppressor Elements: New Tools for Molecular Oncology—Thirteenth Cornelius P. Rhoads Memorial Award Lecture

Igor B. Roninson, Andrei V. Gudkov, Tatyana A. Holzmayer, Deborah J. Kirschling, Alexander R. Kazarov, Carolyn R. Zelnick, Ilya A. Mazo, Sergei Axenovich, and Rama Thimmapaya
Cancer Res 1995 55: 4023-4028. [Abstract] [PDF]  

Biochemistry and Biophysics:

Inhibition of Etoposide (VP-16)-induced DNA Recombination and Mutant Frequency by Bcl-2 Protein Overexpression

Hisako Hashimoto, Satadal Chatterjee, and Nathan A. Berger
Cancer Res 1995 55: 4029-4035. [Abstract] [PDF]  

Monoclonal Antibody BW835 Defines a Site-specific Thomsen-Friedenreich Disaccharide Linked to Threonine within the VTSA Motif of MUC1 Tandem Repeats

Franz-Georg Hanisch, Tanja Stadie, and Klaus Boßlet
Cancer Res 1995 55: 4036-4040. [Abstract] [PDF]  

Carcinogenesis:

Comparison of the Responses of Human Melanocytes with Different Melanin Contents to Ultraviolet B Irradiation

Diane Barker, Kathleen Dixon, Estela E. Medrano, Douglas Smalara, Sungbin Im, David Mitchell, George Babcock, and Zalfa A. Abdel-Malek
Cancer Res 1995 55: 4041-4046. [Abstract] [PDF]  

Ultraviolet B Light Induces G₁ Arrest in Human Melanocytes by Prolonged Inhibition of Retinoblastoma Protein Phosphorylation Associated with Long-Term Expression of the p21^{Waf-1/SDI-1/Cip-1} Protein

Estela E. Medrano, Sungbin Im, Fan Yang, and Zalfa A. Abdel-Malek
Cancer Res 1995 55: 4047-4052. [Abstract] [PDF]  

Chemoprevention of Azoxymethane-induced Colon Carcinogenesis by Dietary Feeding of S-Methyl Methane Thiosulfonate in Male F344 Rats

Toshihiko Kawamori, Takuji Tanaka, Masami Ohnishi, Yoshinobu Hirose, Yasushi Nakamura, Kumiko Satoh, Akira Hara, and Hideki Mori
Cancer Res 1995 55: 4053-4058. [Abstract] [PDF]  

Chemoprevention of Rat Oral Carcinogenesis by Naturally Occurring Xanthophylls, Astaxanthin and Canthaxanthin

Takuji Tanaka, Hiroki Makita, Masami Ohnishi, Hideki Mori, Kumiko Satoh, and Akira Hara
Cancer Res 1995 55: 4059-4064. [Abstract] [PDF]  

Clinical Investigations:

A Polymerase Chain Reaction-based Semiquantitative Assessment of Malignant Melanoma Cells in Peripheral Blood

Peter Brossart, Johann-W. Schmier, Stefan Krüger, Martina Willhauck, Carmen Scheibenbogen, Thomas Möhler, and Ulrich Keilholz
Cancer Res 1995 55: 4065-4068. [Abstract] [PDF]  

A Phase I Trial of Amifostine (WR-2721) and Melphalan in Children with Refractory Cancer

Peter C. Adamson, Frank M. Balis, Jean E. Belasco, Beverly Lange, Stacey L. Berg, Susan M. Blaney, Catherine Craig, and David G. Poplack
Cancer Res 1995 55: 4069-4072. [Abstract] [PDF]  

Experimental Therapeutics:

Transduction of NIH 3T3 Cells with a Retrovirus Carrying Both Human MDR1 and Glutathione S-Transferase Produces Broad-Range Multidrug Resistance

James H. Doroshow, Marianne Z. Metz, Linda Matsumoto, Katherine A. Winters, Masaharu Sakai, Masami Muramatsu, and Susan E. Kane
Cancer Res 1995 55: 4073-4078. [Abstract] [PDF]  

Enhancement of the Selectivity and Antitumor Efficacy of a CC-1065 Analogue through Immunoconjugate Formation

Ravi V. J. Chari, Kristine A. Jackel, Lizabeth A. Bourret, Susan M. Derr, B. Mitra Tadayoni, Kristin M. Mattocks, Sudhir A. Shah, Changnian Liu, Walter A. Blättler, and Victor S. Goldmacher
Cancer Res 1995 55: 4079-4084. [Abstract] [PDF]  

Specific Labeling of O⁶-Alkylguanine-DNA Alkyltransferase by Reaction with O⁶-(p-Hydroxy[³H]methylbenzyl)guanine

Gina M. Ciocco, Robert C. Moschel, Mi-Young Chae, Patricia J. McLaughlin, Ian S. Zagon, and Anthony E. Pegg
Cancer Res 1995 55: 4085-4091. [Abstract] [PDF]  

Molecular Biology and Genetics:

Expression of Pax-2 in Human Renal Cell Carcinoma and Growth Inhibition by Antisense Oligonucleotides

James R. Gnarra and Gregory R. Dressler
Cancer Res 1995 55: 4092-4098. [Abstract] [PDF]  

Interferon System Defects in Human Malignant Melanoma

Claire Linge, Dirk Gewert, Conny Rossmann, Julia A. Newton Bishop, and J. Scott Crowe
Cancer Res 1995 55: 4099-4104. [Abstract] [PDF]  

Cloning, Sequencing, and Functional Analysis of the 5'-Flanking Region of the Rat 3-Hydroxysteroid/Dihydrodiol Dehydrogenase Gene

Hseuh-Kung Lin and Trevor M. Penning
Cancer Res 1995 55: 4105-4113. [Abstract] [PDF]  

Frequent Loss of Heterozygosity at 7q31.1 in Primary Prostate Cancer Is Associated with Tumor Aggressiveness and Progression

Satoru Takahashi, Ailin L. Shan, Steve R. Ritland, Karen A. Delacey, David G. Bostwick, Michael M. Lieber, Stephen N. Thibodeau, and Robert B. Jenkins
Cancer Res 1995 55: 4114-4119. [Abstract] [PDF]  

Tumor Biology:

Stromelysin-3 Is Overexpressed by Stromal Elements in Primary Non-Small Cell Lung Cancers and Regulated by Retinoic Acid in Pulmonary Fibroblasts

Ian C. Anderson, David J. Sugarbaker, Ramesh K. Ganju, Dean G. Tsarwhas, William G. Richards, Mary Sunday, Lester Kobzik, and Margaret A. Shipp
Cancer Res 1995 55: 4120-4126. [Abstract] [PDF]  

Motility Related Protein 1 (MRP-1/CD9) Expression: Inverse Correlation with Metastases in Breast Cancer

Masayuki Miyake, Keiji Nakano, Yoshiaki Ieki, Masashi Adachi, Cheng-Long Huang, Shin-ichi Itoi, Takashi Koh, and Toshihiko Taki
Cancer Res 1995 55: 4127-4131. [Abstract] [PDF]  

Laminin-5 Is a Marker of Invading Cancer Cells in Some Human Carcinomas and Is Coexpressed with the Receptor for Urokinase Plasminogen Activator in Budding Cancer Cells in Colon Adenocarcinomas

Charles Pyke, Sirpa Salo, Elisabeth Ralfkiær, John Rømer, Keld Danø, and Karl Tryggvason
Cancer Res 1995 55: 4132-4139. [Abstract] [PDF]  

Peripheral Blood T Lymphocytes and Lymphocytes Infiltrating Human Cancers Express Vascular Endothelial Growth Factor: A Potential Role for T Cells in Angiogenesis

Michael R. Freeman, Francis X. Schneck, Michael L. Gagnon, Christopher Corless, Shay Soker, Kathy Niknejad, George E. Peoples, and Michael Klagsbrun
Cancer Res 1995 55: 4140-4145. [Abstract] [PDF]  

Growth Inhibition in Response to Estrogen Withdrawal and Tamoxifen Therapy of Human Breast Cancer Xenografts Evaluated by in Vivo ³¹P Magnetic Resonance Spectroscopy, Creatine Kinase Activity, and Apoptotic Index

Claus A. Kristensen, Paul E. G. Kristjansen, Nils Brünner, Bjørn Quistorff, and Mogens Spang-Thomsen
Cancer Res 1995 55: 4146-4150. [Abstract] [PDF]  

The Potential Role of Transformation-induced Metabolic Changes in Tumor-Host Interaction

Robert A. Gatenby
Cancer Res 1995 55: 4151-4156. [Abstract] [PDF]  

CD30 Ligand Signal Transduction Involves Activation of a Tyrosine Kinase and of Mitogen-activated Protein Kinase in a Hodgkin's Lymphoma Cell Line

Clemens-Martin Wendtner, Barbara Schmitt, Hans-Jürgen Gruss, Brian J. Druker, Bertold Emmerich, Raymond G. Goodwin, and Michael Hallek
Cancer Res 1995 55: 4157-4161. [Abstract] [PDF]  

Effects of Anti-Nuclear Factor B Reagents in Blocking Adhesion of Human Cancer Cells to Vascular Endothelial Cells

Keiichi Tozawa, Shinsaku Sakurada, Kenjiro Kohri, and Takashi Okamoto
Cancer Res 1995 55: 4162-4167. [Abstract] [PDF]  

Alterations of Cell Surface Carbohydrates and Inhibition of Metastatic Property of Murine Melanomas by 1,3 Galactosyltransferase Gene Transfection

Elieser Gorelik, Lisa Duty, Farvardin Anaraki, and Uri Galili
Cancer Res 1995 55: 4168-4173. [Abstract] [PDF]  

The 92-kDa Gelatinase B Is Expressed by Advanced Stage Melanoma Cells: Suppression by Somatic Cell Hybridization with Early Stage Melanoma Cells

John R. MacDougall, Maria Rosa Bani, Yulia Lin, Janusz Rak, and Robert S. Kerbel
Cancer Res 1995 55: 4174-4181. [Abstract] [PDF]  

Constitutive Activation of Mitogen-activated Protein (MAP) Kinases in Human Renal Cell Carcinoma

Hiroya Oka, Yuji Chatani, Rika Hoshino, Osamu Ogawa, Yoshiyuki Kakehi, Toshiro Terachi, Yusaku Okada, Masashi Kawaichi, Michiaki Kohno, and Osamu Yoshida
Cancer Res 1995 55: 4182-4187. [Abstract] [PDF]  

c-Myc and Cyclin D3 (CcnD3) Genes Are Independent Targets for Glucocorticoid Inhibition of Lymphoid Cell Proliferation

Kunsoo Rhee, Wade Bresnahan, Aki Hirai, Masashi Hirai, and E. Aubrey Thompson
Cancer Res 1995 55: 4188-4195. [Abstract] [PDF]  

Expression of Thrombomodulin in Esophageal Squamous Cell Carcinoma and Its Relationship to Lymph Node Metastasis

Yoshihisa Tezuka, Suguru Yonezawa, Ikuro Maruyama, Yoshifumi Matsushita, Takeshi Shimizu, Hiroya Obama, Mitsuhisa Sagara, Kazusada Shirao, Chikara Kusano, Shoji Natsugoe, Heiji Yoshinaka, Masamichi Baba, Toshitaka Fukumoto, Takashi Aikou, and Eiichi Sato
Cancer Res 1995 55: 4196-4200. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1995 55: 4201-4203. [PDF]  

Correction

Cancer Res 1995 55: 4203 [PDF]  

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