Advances in Brief:

Evidence of Cumulative Gene Losses with Progression of Premalignant Epithelial Lesions to Carcinoma of the Bronchus

Luc Thiberville, Peter Payne, Jüergen Vielkinds, Jean LeRiche, Douglas Horsman, Georges Nouvet, Branko Palcic, and Stephen Lam
Cancer Res 1995 55: 5133-5139. [Abstract] [PDF]  

Pyruvate Utilization, Phosphocholine and Adenosine Triphosphate (ATP) Are Markers of Human Breast Tumor Progression: A ³¹P- and ¹³C-Nuclear Magnetic Resonance (NMR) Spectroscopy Study

Samuel Singer, Kerry Souza, and William G. Thilly
Cancer Res 1995 55: 5140-5145. [Abstract] [PDF]  

Differential Cellular Expression of the Human MSH2 Repair Enzyme in Small and Large Intestine

Teresa M. Wilson, Amy Ewel, John R. Duguid, John N. Eble, Mary Kay Lescoe, Richard Fishel, and Mark R. Kelley
Cancer Res 1995 55: 5146-5150. [Abstract] [PDF]  

In Vivo Gene Therapy with p53 or p21 Adenovirus for Prostate Cancer

James A. Eastham, Simon J. Hall, Inder Sehgal, Jianxiang Wang, Terry L. Timme, Guang Yang, Lisa Connell-Crowley, Stephen J. Elledge, Wei-Wei Zhang, J. Wade Harper, and Timothy C. Thompson
Cancer Res 1995 55: 5151-5155. [Abstract] [PDF]  

Sodium Phenylacetate Induces Growth Inhibition and Bcl-2 Down-Regulation and Apoptosis in MCF7ras Cells in Vitro and in Nude Mice

Liana Adam, Michel Crépin, Claire Savin, and Lucien Israël
Cancer Res 1995 55: 5156-5160. [Abstract] [PDF]  

Inhibition of Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF) Activity by Suramin and Suramin Analogues Is Correlated to Interaction with the GM-CSF Nucleotide-binding Site

Michael Doukas, Ashok Chavan, Cecelia Gass, Peter Nickel, Thomas Boone, and Boyd Haley
Cancer Res 1995 55: 5161-5163. [Abstract] [PDF]  

Accumulation of Human Promyelocytic Leukemia (HL-60) Cells at Two Energetic Cell Cycle Checkpoints

Susan Sweet and Gurmit Singh
Cancer Res 1995 55: 5164-5167. [Abstract] [PDF]  

Deletion and Altered Regulation of p16^INK4a and p15^INK4b in Undifferentiated Mouse Skin Tumors

Spiros Linardopoulos, Alasdair J. Street, Dawn E. Quelle, David Parry, Gordon Peters, Charles J. Sherr, and Allan Balmain
Cancer Res 1995 55: 5168-5172. [Abstract] [PDF]  

Detection of Mammary Tumor Virus ENV Gene-like Sequences in Human Breast Cancer

Yue Wang, James F. Holland, Ira J. Bleiweiss, Stella Melana, Xiangjun Liu, Isabelle Pelisson, Annette Cantarella, Kathleen Stellrecht, Sridhar Mani, and Beatriz G-T. Pogo
Cancer Res 1995 55: 5173-5179. [Abstract] [PDF]  

Allelic Loss and the Progression of Breast Cancer

Diane M. Radford, Nancy J. Phillips, Keri L. Fair, Jon H. Ritter, Matthew Holt, and Helen Donis-Keller
Cancer Res 1995 55: 5180-5183. [Abstract] [PDF]  

Absence of Secretory Phospholipase A₂ Gene Alterations in Human Colorectal Cancer

Gregory J. Riggins, Sanford Markowitz, James K. Wilson, Bert Vogelstein, and Kenneth W. Kinzler
Cancer Res 1995 55: 5184-5186. [Abstract] [PDF]  

p21 Is Necessary for the p53-mediated G₁ Arrest in Human Cancer Cells

Todd Waldman, Kenneth W. Kinzler, and Bert Vogelstein
Cancer Res 1995 55: 5187-5190. [Abstract] [PDF]  

Loss of Transporter in Antigen Processing 1 Transport Protein and Major Histocompatibility Complex Class I Molecules in Metastatic versus Primary Breast Cancer

Loukas Kaklamanis, Russell Leek, Michael Koukourakis, Kevin C. Gatter, and Adrian L. Harris
Cancer Res 1995 55: 5191-5194. [Abstract] [PDF]  

E-Cadherin Expression Is Silenced by DNA Hypermethylation in Human Breast and Prostate Carcinomas

Jeremy R. Graff, James G. Herman, Rena G. Lapidus, Hemi Chopra, Rosa Xu, David F. Jarrard, William B. Isaacs, Paula M. Pitha, Nancy E. Davidson, and Stephen B. Baylin
Cancer Res 1995 55: 5195-5199. [Abstract] [PDF]  

Lack of Correlation between DNA-dependent Protein Kinase Activity and Tumor Cell Radiosensitivity

M. Joan Allalunis-Turner, Lauri G. Lintott, Geraldine M. Barron, Rufus S. Day, III, and Susan P. Lees-Miller
Cancer Res 1995 55: 5200-5202. [Abstract] [PDF]  

The Differential Expression of Cytokeratin 18 in Cisplatin-sensitive and -resistant Human Ovarian Adenocarcinoma Cells and Its Association with Drug Sensitivity

Hemant K. Parekh and Henry Simpkins
Cancer Res 1995 55: 5203-5206. [Abstract] [PDF]  

Radiation-induced Apoptosis: Effects of Cell Age and Dose Fractionation

C. Clifton Ling, Min Guo, Chang Hu Chen, and Thomas Deloherey
Cancer Res 1995 55: 5207-5212. [Abstract] [PDF]  

Partial Allelotype of Carcinoma in Situ of the Human Bladder

Miriam P. Rosin, Paul Cairns, J. I. Epstein, Mark P. Schoenberg, and David Sidransky
Cancer Res 1995 55: 5213-5216. [Abstract] [PDF]  

p53 Point Mutation and Survival in Colorectal Cancer Patients

Hak-Su Goh, Jocelyn Yao, and Duncan R. Smith
Cancer Res 1995 55: 5217-5221. [Abstract] [PDF]  

Failure to Dephosphorylate Retinoblastoma Protein in Drug-resistant Cells

Q. Ping Dou and Vivian W. Y. Lui
Cancer Res 1995 55: 5222-5225. [Abstract] [PDF]  

Polymorphism in the N-Acetyltransferase 1 (NAT1) Polyadenylation Signal: Association of NAT1*10 Allele with Higher N-Acetylation Activity in Bladder and Colon Tissue

Douglas A. Bell, Alaa F. Badawi, Nicholas P. Lang, Kenneth F. Ilett, Fred F. Kadlubar, and Ari Hirvonen
Cancer Res 1995 55: 5226-5229. [Abstract] [PDF]  

Carcinogenesis:

Role of Aromatic Amine Acetyltransferases, NAT1 and NAT2, in Carcinogen-DNA Adduct Formation in the Human Urinary Bladder

Alaa F. Badawi, Ari Hirvonen, Douglas A. Bell, Nicholas P. Lang, and Fred F. Kadlubar
Cancer Res 1995 55: 5230-5237. [Abstract] [PDF]  

Dose-dependent Promotion Effects of Potassium Chloride on Glandular Stomach Carcinogenesis in Rats after Initiation with N-Methyl-N'-Nitro-N-Nitrosoguanidine and the Synergistic Influence with Sodium Chloride

Akiyoshi Nishikawa, Fumio Furukawa, Masayuki Mitsui, Tomonori Enami, Takayoshi Imazawa, Shinichiro Ikezaki, and Michihito Takahashi
Cancer Res 1995 55: 5238-5241. [Abstract] [PDF]  

Ras-transduced Diethylnitrosamine-treated Hepatocytes Develop into Cancers of Mixed Phenotype in Vivo

Yue-Zhen Lin, Elizabeth M. Brunt, William Bowling, Daniel G. Hafenrichter, Susan C. Kennedy, M. Wayne Flye, and Katherine Parker Ponder
Cancer Res 1995 55: 5242-5250. [Abstract] [PDF]  

Comparative Carcinogenic Effects of Nickel Subsulfide, Nickel Oxide, or Nickel Sulfate Hexahydrate Chronic Exposures in the Lung

June K. Dunnick, Michael R. Elwell, Ann E. Radovsky, Janet M. Benson, Fletcher F. Hahn, Kristan J. Nikula, Edward B. Barr, and Charles H. Hobbs
Cancer Res 1995 55: 5251-5256. [Abstract] [PDF]  

Mechanism of Action of Chemoprotective Ursodeoxycholate in the Azoxymethane Model of Rat Colonic Carcinogenesis: Potential Roles of Protein Kinase C-, -ß_II, and -

Ramesh K. Wali, Brendan P. Frawley, Jr., Susanne Hartmann, Hemant K. Roy, Sharad Khare, Beth A. Scaglione-Sewell, David L. Earnest, Michael D. Sitrin, Thomas A. Brasitus, and Marc Bissonnette
Cancer Res 1995 55: 5257-5264. [Abstract] [PDF]  

Renal Tubular Tumors and Atypical Hyperplasias in B6C3F₁ Mice Exposed to Lead Acetate during Gestation and Lactation Occur with Minimal Chronic Nephropathy

Michael P. Waalkes, Bhalchandra A. Diwan, Jerrold M. Ward, Deborah E. Devor, and Robert A. Goyer
Cancer Res 1995 55: 5265-5271. [Abstract] [PDF]  

Endocrinology:

Relaxin Activates the L-Arginine-Nitric Oxide Pathway in Human Breast Cancer Cells

Daniele Bani, Emanuela Masini, Maria Grazia Bello, Mario Bigazzi, and Tatiana Bani Sacchi
Cancer Res 1995 55: 5272-5275. [Abstract] [PDF]  

Experimental Therapeutics:

Chemosensitivity Testing of Human Tumors Using a Microplate Adenosine Triphosphate Luminescence Assay: Clinical Correlation for Cisplatin Resistance of Ovarian Carcinoma

Peter E. Andreotti, Ian A. Cree, Christian M. Kurbacher, Diana M. Hartmann, Dee Linder, Guy Harel, Ira Gleiberman, Phillip A. Caruso, Sharon H. Ricks, Michael Untch, Christian Sartori, and Howard W. Bruckner
Cancer Res 1995 55: 5276-5282. [Abstract] [PDF]  

Adenovirus-mediated Gene Therapy of Hepatocellular Carcinoma Using Cancer-specific Gene Expression

Shuichi Kaneko, Paul Hallenbeck, Toshi Kotani, Hidekazu Nakabayashi, Gary McGarrity, Taiki Tamaoki, W. French Anderson, and Yawen L. Chiang
Cancer Res 1995 55: 5283-5287. [Abstract] [PDF]  

Lysine Reduces Renal Accumulation of Radioactivity Associated with Injection of the [¹⁷⁷Lu]-[2-(4-Aminophenyl) ethyl]-1,4,7,10-tetraaza-cyclodecane-1,4,7,10-tetraacetic acid-CC49 Fab Radioimmunoconjugate

Louis R. DePalatis, Kevin A. Frazier, Roberta C. Cheng, and Nicolas J. Kotite
Cancer Res 1995 55: 5288-5295. [Abstract] [PDF]  

Inhibition of Tumor Growth and Metastasis by an Immunoneutralizing Monoclonal Antibody to Human Vascular Endothelial Growth Factor/Vascular Permeability Factor₁₂₁

Makoto Asano, Ayako Yukita, Tomoe Matsumoto, Shinichi Kondo, and Hideo Suzuki
Cancer Res 1995 55: 5296-5301. [Abstract] [PDF]  

A Peptidomimetic Inhibitor of Farnesyl:Protein Transferase Blocks the Anchorage-dependent and -independent Growth of Human Tumor Cell Lines

Laura Sepp-Lorenzino, Zhenping Ma, Elaine Rands, Nancy E. Kohl, Jackson B. Gibbs, Allen Oliff, and Neal Rosen
Cancer Res 1995 55: 5302-5309. [Abstract] [PDF]  

Inhibition of Human Tumor Xenograft Growth by Treatment with the Farnesyl Transferase Inhibitor B956

Takeshi Nagasu, Kentaro Yoshimatsu, Cheryl Rowell, Michael D. Lewis, and Ana Maria Garcia
Cancer Res 1995 55: 5310-5314. [Abstract] [PDF]  

Design and Analysis of in Vitro Antitumor Pharmacodynamic Studies

John E. Kalns, Nancy J. Millenbaugh, M. Guillaume Wientjes, and Jessie L-S. Au
Cancer Res 1995 55: 5315-5322. [Abstract] [PDF]  

Immunology:

Biodistribution of ¹⁸F- and ¹²⁵I-labeled Anti-Tac Disulfide-stabilized Fv Fragments in Nude Mice with Interleukin 2 Receptor-positive Tumor Xenografts

C. W. Choi, L. Lang, J. T. Lee, K. O. Webber, T. M. Yoo, H. K. Chang, N. Le, E. Jagoda, C. H. Paik, I. Pastan, W. C. Eckelman, and J. A. Carrasquillo
Cancer Res 1995 55: 5323-5329. [Abstract] [PDF]  

Generation of Antimelanoma Cytotoxic T Lymphocytes from Healthy Donors after Presentation of Melanoma-associated Antigen-derived Epitopes by Dendritic Cells in Vitro

Alexander B. H. Bakker, Gill Marland, Annemiek J. de Boer, Richard J. F. Huijbens, Erik H. J. Danen, Gosse J. Adema, and Carl G. Figdor
Cancer Res 1995 55: 5330-5334. [Abstract] [PDF]  

In Vivo Antitumor Effects of Unconjugated CD30 Monoclonal Antibodies on Human Anaplastic Large-Cell Lymphoma Xenografts

Zhi-Gang Tian, Dan L. Longo, Satoshi Funakoshi, Osamu Asai, Douglas K. Ferris, Michael Widmer, and William J. Murphy
Cancer Res 1995 55: 5335-5341. [Abstract] [PDF]  

Molecular Biology and Genetics:

Expression of Multidrug Resistance-associated Protein in NIH/3T3 Cells Confers Multidrug Resistance Associated with Increased Drug Efflux and Altered Intracellular Drug Distribution

Lisa M. Breuninger, Saptarshi Paul, Kathleen Gaughan, Toru Miki, Andrew Chan, Stuart A. Aaronson, and Gary D. Kruh
Cancer Res 1995 55: 5342-5347. [Abstract] [PDF]  

Loss of Heterozygosity at the Familial RCC t(3;8) Locus in Most Clear Cell Renal Carcinomas

Teresa Druck, Kumar Kastury, Piotr Hadaczek, Jacek Podolski, Aleksandra Toloczko, Andrzej Sikorski, Masataka Ohta, Sal LaForgia, Jerzy Lasota, Peter McCue, Jan Lubinski, and Kay Huebner
Cancer Res 1995 55: 5348-5353. [Abstract] [PDF]  

Distinct Mutational Spectrum of the p53 Gene in Lung Cancers from Chinese Women in Hong Kong

Yukihiro Takagi, Linda C. Koo, Hirotaka Osada, Ryuzo Ueda, Kyaw Kyaw, Chan-chung Ma, Motokazu Suyama, Shigetoyo Saji, Toshitada Takahashi, Suketami Tominaga, and Takashi Takahashi
Cancer Res 1995 55: 5354-5357. [Abstract] [PDF]  

Ornithine Decarboxylase Transformation of NIH/3T3 Cells Is Mediated by Altered Epidermal Growth Factor Receptor Activity

Jeffrey A. Moshier, Ewa Malecka-Panas, Hairong Geng, Julie Dosescu, John Tureaud, Magdalena Skunca, and Adhip P. N. Majumdar
Cancer Res 1995 55: 5358-5365. [Abstract] [PDF]  

The 1p Deletion Is Not a Reliable Marker for the Prognosis of Patients with Neuroblastoma

Manuela Gehring, Frank Berthold, Lutz Edler, Manfred Schwab, and Lukas C. Amler
Cancer Res 1995 55: 5366-5369. [Abstract] [PDF]  

Suppression of Rat Glutathione Transferase P Expression by Peroxisome Proliferators: Interaction between Jun and Peroxisome Proliferator-activated Receptor

Masaharu Sakai, Yuko Matsushima-Hibiya, Makoto Nishizawa, and Shinzo Nishi
Cancer Res 1995 55: 5370-5376. [Abstract] [PDF]  

Allelotype Analysis of Childhood Acute Lymphoblastic Leukemia

Seisho Takeuchi, Claus R. Bartram, Makio Wada, Alfred Reiter, Yoshihiro Hatta, Taku Seriu, Elizabeth Lee, Carl W. Miller, Isao Miyoshi, and H. Phillip Koeffler
Cancer Res 1995 55: 5377-5382. [Abstract] [PDF]  

Terminal Deletion of Chromosome 3p Sequences in Nonpapillary Renal Cell Carcinomas: A Breakpoint Cluster between Loci D3S1285 and D3S1603

Mónica Wilhelm, Peter Bugert, Christiane Kenck, Gerd Staehler, and Gyula Kovacs
Cancer Res 1995 55: 5383-5385. [Abstract] [PDF]  

Regulation of the Proto-oncogenes bcl-2 and c-myc by the Wilms' Tumor Suppressor Gene WT1

Stephen M. Hewitt, Shinshichi Hamada, Timothy J. McDonnell, Frank J. Rauscher, III, and Grady F. Saunders
Cancer Res 1995 55: 5386-5389. [Abstract] [PDF]  

Evidence for Three Tumor Suppressor Gene Loci on Chromosome 8p in Human Prostate Cancer

Jill A. Macoska, Tanya M. Trybus, Philip D. Benson, Wael A. Sakr, David J. Grignon, Kirk D. Wojno, Teresa Pietruk, and Isaac J. Powell
Cancer Res 1995 55: 5390-5395. [Abstract] [PDF]  

Distinct Regions of Allelic Loss on Chromosome 4 in Human Primary Bladder Carcinoma

Thomas J. Polascik, Paul Cairns, Wayne Y. H. Chang, Mark P. Schoenberg, and David Sidransky
Cancer Res 1995 55: 5396-5399. [Abstract] [PDF]  

ERBB-2 (HER2/neu) Gene Copy Number, p185^HER-2 Overexpression, and Intratumor Heterogeneity in Human Breast Cancer

János Szöllösi, Margit Balázs, Burt G. Feuerstein, Christopher C. Benz, and Frederic M. Waldman
Cancer Res 1995 55: 5400-5407. [Abstract] [PDF]  

Chromosomal Anomalies in Prostatic Intraepithelial Neoplasia and Carcinoma Detected by Fluorescence in Situ Hybridization

Junqi Qian, David G. Bostwick, Satoru Takahashi, Thomas J. Borell, John F. Herath, Michael M. Lieber, and Robert B. Jenkins
Cancer Res 1995 55: 5408-5414. [Abstract] [PDF]  

Tumor Biology:

Comparative Genomic Hybridization of Formalin-fixed, Paraffin-embedded Breast Tumors Reveals Different Patterns of Chromsomal Gains and Losses in Fibroadenomas and Diploid and Aneuploid Carcinomas

Thomas Ried, Kelly E. Just, Heidi Holtgreve-Grez, Stanislas du Manoir, Michael R. Speicher, Evelin Schröck, Carolyn Latham, Harald Blegen, Anders Zetterberg, Thomas Cremer, and Gert Auer
Cancer Res 1995 55: 5415-5423. [Abstract] [PDF]  

CD44 Isoforms Correlate with Cellular Differentiation but not with Prognosis in Human Breast Cancer

Kay Friedrichs, Folker Franke, Björn-Wieland Lisboa, Gerd Kügler, Ingbert Gille, Hans-Joachim Terpe, Fritz Hölzel, Heinrich Maass, and Ursula Günthert
Cancer Res 1995 55: 5424-5433. [Abstract] [PDF]  

Increase in Suprabasilar Integrin Adhesion Molecule Expression in Human Epidermal Neoplasms Accompanies Increased Proliferation Occurring with Immortalization and Tumor Progression

Carter Van Waes, Dong Mi Surh, Zhong Chen, Martha Kirby, Johng S. Rhim, Robert Brager, Roy B. Sessions, Judy Poore, Gregory T. Wolf, and Thomas E. Carey
Cancer Res 1995 55: 5434-5444. [Abstract] [PDF]  

Cloning of a Brain-type Isoform of Human Rab GDI and Its Expression in Human Neuroblastoma Cell Lines and Tumor Specimens

Noriyuki Nishimura, Junko Goji, Hajime Nakamura, Satoshi Orita, Yoshimi Takai, and Kimihiko Sano
Cancer Res 1995 55: 5445-5450. [Abstract] [PDF]  

Time-dependent Behavior of Interstitial Fluid Pressure in Solid Tumors: Implications for Drug Delivery

Paolo A. Netti, Laurence T. Baxter, Yves Boucher, Richard Skalak, and Rakesh K. Jain
Cancer Res 1995 55: 5451-5458. [Abstract] [PDF]  

Apoptosis in Tumors and Normal Tissues Induced by Whole Body Hyperthermia in Rats

Yoshihisa Sakaguchi, L. Clifton Stephens, Masato Makino, Tetsuya Kaneko, Frederick R. Strebel, Lynn L. Danhauser, Gaye N. Jenkins, and Joan M. C. Bull
Cancer Res 1995 55: 5459-5464. [Abstract] [PDF]  

Virology:

Integrated Human Papillomavirus Type 16 and Loss of Heterozygosity at 11q22 and 18q21 in an Oral Carcinoma and Its Derivative Cell Line

Renske D. M. Steenbergen, Mario A. J. A. Hermsen, Jan M. M. Walboomers, Hans Joenje, Fré Arwert, Chris J. L. M. Meijer, and Peter J. F. Snijders
Cancer Res 1995 55: 5465-5471. [Abstract] [PDF]  

Meeting Report:

Molecular Biology of Cancer: Implications for Prevention and Therapy—Third Joint Meeting of the American Association for Cancer Research and the Japanese Cancer Association

Lee W. Wattenberg and Masaaki Terada
Cancer Res 1995 55: 5472-5481. [PDF]  

Articles:

Announcements

Cancer Res 1995 55: 5482-5484. [PDF]  

Errata

Cancer Res 1995 55: 5485 [PDF]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.