Perspectives in Cancer Research:

Mismatch Repair, Somatic Mutations, and the Origins of Cancer

Donald G. MacPhee
Cancer Res 1995 55: 5489-5492. [Abstract] [PDF]  

Advances in Brief:

Retroviral Vector-mediated Gene Transfer of Antisense Cyclin G1 (CYCG1) Inhibits Proliferation of Human Osteogenic Sarcoma Cells

Michael Skotzko, Lingtao Wu, W. French Anderson, Erlinda M. Gordon, and Frederick L. Hall
Cancer Res 1995 55: 5493-5498. [Abstract] [PDF]  

Differential Expression of CD44 Splice Variants in Human Pancreatic Adenocarcinoma and in Normal Pancreas

Frank Gansauge, Susanne Gansauge, Anke Zobywalski, Christian Scharnweber, Karl H. Link, Andreas K. Nussler, and Hans G. Beger
Cancer Res 1995 55: 5499-5503. [Abstract] [PDF]  

Human Homologue of a Candidate for the Mom1 Locus, the Secretory Type II Phospholipase A₂ (PLA2S-II), Maps to 1p35-36.1/D1S199

Christian Praml, Larissa Savelyeva, Denis Le Paslier, Linda D. Siracusa, Arthur M. Buchberg, Manfred Schwab, and Lukas C. Amler
Cancer Res 1995 55: 5504-5506. [Abstract] [PDF]  

Anti-Retinoic Acid (RA) Antibody Binding to Human Premalignant Oral Lesions, Which Occurs Less Frequently Than Binding to Normal Tissue, Increases after 13-cis-RA Treatment in Vivo and Is Related to RA Receptor ß Expression

Xiao-Chun Xu, Maija H. Zile, Scott M. Lippman, Jin S. Lee, Jack J. Lee, Waun K. Hong, and Reuben Lotan
Cancer Res 1995 55: 5507-5511. [Abstract] [PDF]  

Mitogen-activated Protein Kinase Acts as a Negative Regulator of the Heat Shock Response in NIH3T3 Cells

Nahid F. Mivechi and Amato J. Giaccia
Cancer Res 1995 55: 5512-5519. [Abstract] [PDF]  

Human Glutathione S-Transferase M1 Null Genotype Is Associated with a High Inducibility of Cytochrome P450 1A1 Gene Transcription

Christelle Vaury, Romuald Lainé, Patricia Noguiez, Pierre de Coppet, Christian Jaulin, Françoise Praz, Denis Pompon, and Mounira Amor-Guéret
Cancer Res 1995 55: 5520-5523. [Abstract] [PDF]  

In Vivo Cisplatin-exposed Macrophages Increase Immunostimulant-induced Nitric Oxide Synthesis for Tumor Cell Killing

Kyonghee Son and Young-Myeong Kim
Cancer Res 1995 55: 5524-5527. [Abstract] [PDF]  

Expression of Fas/APO-1 during the Progression of Astrocytomas

Osamu Tachibana, Hisayoshi Nakazawa, Johannes Lampe, Kunihiko Watanabe, Paul Kleihues, and Hiroko Ohgaki
Cancer Res 1995 55: 5528-5530. [Abstract] [PDF]  

Homozygous Loss of the p15^INK4B Gene (and not the p16^INK4 Gene) during Tumor Progression in a Sporadic Melanoma Patient

J. Michael Glendening, José F. Flores, Graeme J. Walker, Steven Stone, Anthony P. Albino, and Jane W. Fountain
Cancer Res 1995 55: 5531-5535. [Abstract] [PDF]  

Frequent Expression of a Mutant Epidermal Growth Factor Receptor in Multiple Human Tumors

David K. Moscatello, Marina Holgado-Madruga, Andrew K. Godwin, Gloria Ramirez, George Gunn, Philip W. Zoltick, Jaclyn A. Biegel, Roberta L. Hayes, and Albert J. Wong
Cancer Res 1995 55: 5536-5539. [Abstract] [PDF]  

The Oncogene qin Codes for a Transcriptional Repressor

Jian Li, Hwai Wen Chang, Eseng Lai, Elizabeth J. Parker, and Peter K. Vogt
Cancer Res 1995 55: 5540-5544. [Abstract] [PDF]  

A Transforming Growth Factor ß Receptor Type II Gene Mutation Common in Colon and Gastric but Rare in Endometrial Cancers with Microsatellite Instability

Lois L. Myeroff, Ramon Parsons, Seong-Jin Kim, Lora Hedrick, Kathleen R. Cho, Kim Orth, Michael Mathis, Kenneth W. Kinzler, James Lutterbaugh, Keunchil Park, Yung-Jue Bang, Hwa Young Lee, Jae-Gahb Park, Henry T. Lynch, Anita B. Roberts, Bert Vogelstein, and Sanford D. Markowitz
Cancer Res 1995 55: 5545-5547. [Abstract] [PDF]  

Microsatellite Instability and Mutations of the Transforming Growth Factor ß Type II Receptor Gene in Colorectal Cancer

Ramon Parsons, Lois L. Myeroff, Bo Liu, James K. V. Willson, Sanford D. Markowitz, Kenneth W. Kinzler, and Bert Vogelstein
Cancer Res 1995 55: 5548-5550. [Abstract] [PDF]  

Adenovirus Ela-mediated Tumor Suppression by a c-erbB-2/neu-independent Mechanism

Steven M. Frisch and Karen E. Dolter
Cancer Res 1995 55: 5551-5555. [Abstract] [PDF]  

Mutations in DNA Mismatch Repair Genes Are Not Responsible for Microsatellite Instability in Most Sporadic Endometrial Carcinomas

Hidetaka Katabuchi, Bastiaan van Rees, Anouk R. Lambers, Brigitte M. Ronnett, Marian S. Blazes, Fred S. Leach, Kathleen R. Cho, and Lora Hedrick
Cancer Res 1995 55: 5556-5560. [Abstract] [PDF]  

Genetic Radiotherapy Overcomes Tumor Resistance to Cytotoxic Agents

Lisa P. Seung, Helena J. Mauceri, Michael A. Beckett, Dennis E. Hallahan, Samuel Hellman, and Ralph R. Weichselbaum
Cancer Res 1995 55: 5561-5565. [Abstract] [PDF]  

Carcinogenesis:

Activation of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Human Lung Microsomes by Cytochromes P450, Lipoxygenase, and Hydroperoxides

Theresa J. Smith, Gary D. Stoner, and Chung S. Yang
Cancer Res 1995 55: 5566-5573. [Abstract] [PDF]  

Inhibition of CYP1A2 and CYP3A4 by Oltipraz Results in Reduction of Aflatoxin B₁ Metabolism in Human Hepatocytes in Primary Culture

Sophie Langouët, Brian Coles, Fabrice Morel, Laurent Becquemont, Philippe Beaune, F. Peter Guengerich, Brian Ketterer, and André Guillouzo
Cancer Res 1995 55: 5574-5579. [Abstract] [PDF]  

Effects of Phenethyl Isothiocyanate on the Tissue Distribution of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Metabolites in F344 Rats

Marianne E. Staretz and Stephen S. Hecht
Cancer Res 1995 55: 5580-5588. [Abstract] [PDF]  

Carcinogenicity Studies of Astemizole in Mice and Rats

Johanna Benze, Ludo Gypen, John Vandenberghe, Ann Lampo, Roland De Coster, Charles Bowden, and Herman Van Cauteren
Cancer Res 1995 55: 5589-5594. [Abstract] [PDF]  

Enhanced Apoptosis Predicts Shortened Survival in Non-Small Cell Lung Carcinoma

Ulla Törmänen, Anna-Kaisa Eerola, Pekka Rainio, Kirsi Vähäkangas, Ylermi Soini, Raija Sormunen, Risto Bloigu, Veli-Pekka Lehto, and Paavo Pääkkö
Cancer Res 1995 55: 5595-5602. [Abstract] [PDF]  

Retinoid Refractoriness Occurs during Lung Carcinogenesis Despite Functional Retinoid Receptors

Yeul-Hong Kim, David F. Dohi, Gil Ro Han, Chang-Ping Zou, Nobuhiko Oridate, Garrett L. Walsh, Jonathan C. Nesbitt, Xiao-Chun Xu, Waun Ki Hong, Reuben Lotan, and Jonathan M. Kurie
Cancer Res 1995 55: 5603-5610. [Abstract] [PDF]  

High Levels of DNA Adducts in Human Colon Are Associated with Colorectal Cancer

Annie Pfohl-Leszkowicz, Yann Grosse, Véronique Carrière, Paul-Henri Cugnenc, Anne Berger, Françoise Carnot, Philippe Beaune, and Isabelle de Waziers
Cancer Res 1995 55: 5611-5616. [Abstract] [PDF]  

Oncogenic Rearrangements of the RET Proto-Oncogene in Papillary Thyroid Carcinomas from Children Exposed to the Chernobyl Nuclear Accident

Laura Fugazzola, Silvana Pilotti, Aldo Pinchera, Tatiana V. Vorontsova, Piera Mondellini, Italia Bongarzone, Angela Greco, Larisa Astakhova, Marta G. Butti, Eugene P. Demidchik, Furio Pacini, and Marco A. Pierotti
Cancer Res 1995 55: 5617-5620. [Abstract] [PDF]  

Chemopreventive Activity of Tamoxifen, N-(4-Hydroxyphenyl)retinamide, and the Vitamin D Analogue Ro24-5531 for Androgen-promoted Carcinomas of the Rat Seminal Vesicle and Prostate

M. Scott Lucia, Mario A. Anzano, Michael V. Slayter, Miriam R. Anver, Darlene M. Green, Mark W. Shrader, Daniel L. Logsdon, Craig L. Driver, Charles C. Brown, Christopher W. Peer, Anita B. Roberts, and Michael B. Sporn
Cancer Res 1995 55: 5621-5627. [Abstract] [PDF]  

Clinical Investigations:

The Distribution of the Deleted in Colon Cancer (DCC) Protein in Human Tissues

Helen Turley, Francesco Pezzella, Sylvia Kocialkowski, Margaret Comley, Loukas Kaklamanis, Jon Fawcett, David Simmons, Adrian L. Harris, and Kevin C. Gatter
Cancer Res 1995 55: 5628-5631. [Abstract] [PDF]  

Endocrinology:

Morphine Cross-Reacts with Somatostatin Receptor SSTR2 in the T47D Human Breast Cancer Cell Line and Decreases Cell Growth

Anastassia Hatzoglou, L'Houcine Ouafik, Efstathia Bakogeorgou, Kyriaki Thermos, and Elias Castanas
Cancer Res 1995 55: 5632-5636. [Abstract] [PDF]  

Experimental Therapeutics:

Growth Inhibition of Human Cancer Metastases by Camptothecins in Newly Developed Xenograft Models

Milan Potmesil, Dana Vardeman, Anthony J. Kozielski, John Mendoza, John S. Stehlin, and Beppino C. Giovanella
Cancer Res 1995 55: 5637-5641. [Abstract] [PDF]  

Immunology:

B-Lymphoma Cells Are Activated by Peptide Ligands of the Antigen Binding Receptor or by Anti-Idiotypic Antibody to Induce Extracellular Acidification

Markus F. Renschler, H. Garrett Wada, Katherine S. Fok, and Ronald Levy
Cancer Res 1995 55: 5642-5647. [Abstract] [PDF]  

Methylcholanthrene-induced Mouse Sarcomas Express Individually Distinct Major Histocompatibility Complex Class I-associated Peptides Recognized by Specific CD8+ T-Cell Lines

Koji Kono, Max Petersson, Anne-Marie T. Ciupitu, Tao Wen, George Klein, and Rolf Kiessling
Cancer Res 1995 55: 5648-5655. [Abstract] [PDF]  

Molecular Biology and Genetics:

Defects in the DNA Repair and Transcription Gene ERCC2 in the Cancer-prone Disorder Xeroderma Pigmentosum Group D

Kyoko Takayama, Edmund P. Salazar, Alan Lehmann, Miria Stefanini, Larry H. Thompson, and Christine A. Weber
Cancer Res 1995 55: 5656-5663. [Abstract] [PDF]  

Microsatellite Instability in Gynecological Sarcomas and in hMSH2 Mutant Uterine Sarcoma Cell Lines Defective in Mismatch Repair Activity

John I. Risinger, Asad Umar, Jayne C. Boyer, A. Craig Evans, Andrew Berchuck, Thomas A. Kunkel, and J. Carl Barrett
Cancer Res 1995 55: 5664-5669. [Abstract] [PDF]  

Association of Minisatellite Instability with c-myc Amplification and K-ras Mutation in Methylcholanthrene-induced Mouse Sarcomas

Ohtsura Niwa, Kenji Kamiya, Chie Furihata, Yumiko Nitta, Zhongwen Wang, Yi-Jun Fan, Yasuharu Ninomiya, Naoe Kotomura, Michitaka Numoto, and Ryo Kominami
Cancer Res 1995 55: 5670-5676. [Abstract] [PDF]  

Alterations of Microsatellites in Neurofibromas of von Recklinghausen's Disease

Laura Ottini, Diana L. Esposito, Antonio Richetta, Marta Carlesimo, Raffaele Palmirotta, Maria Concetta Verì, Pasquale Battista, Luigi Frati, Felice Giacomo Caramia, Stefano Calvieri, Alessandro Cama, and Renato Mariani-Costantini
Cancer Res 1995 55: 5677-5680. [Abstract] [PDF]  

Deletion of Chromosome 1p Loci and Microsatellite Instability in Neuroblastomas Analyzed with Short-Tandem Repeat Polymorphisms

Tommy Martinsson, Rose-Marie Sjöberg, Fredrik Hedborg, and Per Kogner
Cancer Res 1995 55: 5681-5686. [Abstract] [PDF]  

Tumor Biology:

Expression of the Vascular Endothelial Growth Factor (VEGF) Receptor Gene, KDR, in Hematopoietic Cells and Inhibitory Effect of VEGF on Apoptotic Cell Death Caused by Ionizing Radiation

Osamu Katoh, Hiroshi Tauchi, Kuniko Kawaishi, Akiro Kimura, and Yukio Satow
Cancer Res 1995 55: 5687-5692. [Abstract] [PDF]  

Amplification and Overexpression of HER-2/neu (c-erbB2) in Endometrial Cancers: Correlation with Overall Survival

Bahman Saffari, Lovell A. Jones, Adel El-Naggar, Juan C. Felix, Jay George, and Michael F. Press
Cancer Res 1995 55: 5693-5698. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1995 55: 5699-5700. [PDF]  

Recent Death

Cancer Res 1995 55: 5700 [PDF]  

Calendar of Events

Cancer Res 1995 55: 5700-5701. [PDF]  

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