Advances in Brief:

Sequential Coexpression of the Multidrug Resistance Genes MRP and mdr1 and Their Products in VP-16 (Etoposide)-selected H69 Small Cell Lung Cancer Cells

Inger Brock, David R. Hipfner, Boye S. Nielsen, Peter B. Jensen, Roger G. Deeley, Susan P. C. Cole, and Maxwell Sehested
Cancer Res 1995 55: 459-462. [Abstract] [PDF]  

Cytotoxic T Cells Overcome BCR-ABL-mediated Resistance to Apoptosis

Ephraim J. Fuchs, Atul Bedi, Richard J. Jones, and Allan D. Hess
Cancer Res 1995 55: 463-466. [Abstract] [PDF]  

Identical Allelic Loss on Chromosome 11q13 in Microdissected in Situ and Invasive Human Breast Cancer

Zhengping Zhuang, Maria J. Merino, Rodrigo Chuaqui, Lance A. Liotta, and Michael R. Emmert-Buck
Cancer Res 1995 55: 467-471. [Abstract] [PDF]  

A Specific African-American CYP1A1 Polymorphism Is Associated with Adenocarcinoma of the Lung

Emanuela Taioli, Frances Crofts, Julie Trachman, Rita Demopoulos, Paolo Toniolo, and Seymour J. Garte
Cancer Res 1995 55: 472-473. [Abstract] [PDF]  

Metallothionein Localization and Cisplatin Resistance in Human Hormone-independent Prostatic Tumor Cell Lines

Yukihiro Kondo, Shiu-Ming Kuo, Simon C. Watkins, and John S. Lazo
Cancer Res 1995 55: 474-477. [Abstract] [PDF]  

Methotrexate--Phenylalanine: Optimization of Methotrexate Prodrug for Activation by Carboxypeptidase A-Monoclonal Antibody Conjugate

Karin S. Vitols, Brigitte Haag-Zeino, Thomas Baer, Yolanda D. Montejano, and F. M. Huennekens
Cancer Res 1995 55: 478-481. [Abstract] [PDF]  

Pharmacokinetics of 9-cis-Retinoic Acid in the Rhesus Monkey

Peter C. Adamson, Robert F. Murphy, Karen A. Godwin, Edgar H. Ulm, and Frank M. Balis
Cancer Res 1995 55: 482-485. [Abstract] [PDF]  

Apoptin, a Protein Derived from Chicken Anemia Virus, Induces p53-independent Apoptosis in Human Osteosarcoma Cells

Shi-Mei Zhuang, Avi Shvarts, Hans van Ormondt, Aart G. Jochemsen, Alex J. van der Eb, and Mathieu H. M. Noteborn
Cancer Res 1995 55: 486-489. [Abstract] [PDF]  

Evidence for a Multifocal Origin of Papillary Serous Carcinoma of the Peritoneum

Michael G. Muto, William R. Welch, Samuel Chi-Ho Mok, Christina A. Bandera, Paula M. Fishbaugh, Sai-Wah Tsao, Ching C. Lau, Howard M. Goodman, Robert C. Knapp, and Ross S. Berkowitz
Cancer Res 1995 55: 490-492. [Abstract] [PDF]  

Increased p16 Levels Correlate with pRb Alterations in Human Urothelial Cells

Thomas Yeager, Walter Stadler, Cassandra Belair, Jairaj Puthenveettil, Olufunmilayo Olopade, and Catherine Reznikoff
Cancer Res 1995 55: 493-497. [Abstract] [PDF]  

Variant Estrogen Receptor Messenger RNA Species Detected in Human Primary Hepatocellular Carcinoma

Erica Villa, Lorenzo Camellini, Aisha Dugani, Fabrizio Zucchi, Antonella Grottola, Annalisa Merighi, Paola Buttafoco, Lorena Losi, and Federico Manenti
Cancer Res 1995 55: 498-500. [Abstract] [PDF]  

Acceleration of Apoptosis in Transforming Growth Factor ß1-treated M1 Cells Ectopically Expressing B-myb

Juraj Bies and Linda Wolff
Cancer Res 1995 55: 501-504. [Abstract] [PDF]  

Reciprocal Rb Inactivation and p16^INK4 Expression in Primary Lung Cancers and Cell Lines

Geoffrey I. Shapiro, Christian D. Edwards, Lester Kobzik, John Godleski, William Richards, David J. Sugarbaker, and Barrett J. Rollins
Cancer Res 1995 55: 505-509. [Abstract] [PDF]  

Different Angiogenic Pathways Characterize Superficial and Invasive Bladder Cancer

Tim O'Brien, David Cranston, Susan Fuggle, Roy Bicknell, and Adrian L. Harris
Cancer Res 1995 55: 510-513. [Abstract] [PDF]  

In Vivo Occurrence of p16 (MTS1) and p15 (MTS2) Alterations Preferentially in Non-Small Cell Lung Cancers

Osuke Washimi, Masaaki Nagatake, Hirotaka Osada, Ryuzo Ueda, Takashi Koshikawa, Tsuneo Seki, Toshitada Takahashi, and Takashi Takahashi
Cancer Res 1995 55: 514-517. [Abstract] [PDF]  

Biochemistry and Biophysics:

Translocation and Activation of Protein Kinase C by the Plasma Cell Tumor-promoting Alkane Pristane

Siegfried Janz, Klaus Gawrisch, and David S. Lester
Cancer Res 1995 55: 518-524. [Abstract] [PDF]  

Carcinogenesis:

Metabolic Activation of N-Hydroxy Arylamines and N-Hydroxy Heterocyclic Amines by Human Sulfotransferase(s)

H-C. Chou, N. P. Lang, and F. F. Kadlubar
Cancer Res 1995 55: 525-529. [Abstract] [PDF]  

Autocrine Growth Stimulation by Transforming Growth Factor in Asbestos-transformed Rat Mesothelial Cells

Cheryl Walker, Jeffrey Everitt, Patrice C. Ferriola, Wendy Stewart, James Mangum, and Edilberto Bermudez
Cancer Res 1995 55: 530-536. [Abstract] [PDF]  

Evaluation of Chemopreventive Agents in Different Mechanistic Classes Using a Rat Tracheal Epithelial Cell Culture Transformation Assay

Julia T. Arnold, Betty P. Wilkinson, Sheela Sharma, and Vernon E. Steele
Cancer Res 1995 55: 537-543. [Abstract] [PDF]  

Tamoxifen Induces Short-Term Cumulative DNA Damage and Liver Tumors in Rats: Promotion by Phenobarbital

Philip Carthew, Elizabeth A. Martin, Ian N. H. White, Francesco De Matteis, Richard E. Edwards, Barbara M. Dorman, Robert T. Heydon, and Lewis L. Smith
Cancer Res 1995 55: 544-547. [Abstract] [PDF]  

Endocrinology:

Modulator Inhibits Nuclear Translocation of the Glucocorticoid Receptor and Inhibits Glucocorticoid-induced Apoptosis in the Human Leukemic Cell Line CEM C-7

Noreen M. Robertson, Peter V. N. Bodine, Tin-Chen Hsu, Emad S. Alnemri, and Gerald Litwack
Cancer Res 1995 55: 548-556. [Abstract] [PDF]  

Epidemiology:

A Case-Control Study of Nonrandom Distribution of Bleomycin-induced Chromatid Breaks in Lymphocytes of Lung Cancer Cases

Xifeng Wu, T.C. Hsu, John F. Annegers, Christopher I. Amos, John J. Fueger, and Margaret R. Spitz
Cancer Res 1995 55: 557-561. [Abstract] [PDF]  

Age at Establishment of Helicobacter pylori Infection and Gastric Carcinoma, Gastric Ulcer, and Duodenal Ulcer Risk

Martin J. Blaser, P. H. Chyou, and Abraham Nomura
Cancer Res 1995 55: 562-565. [Abstract] [PDF]  

Experimental Therapeutics:

Multifactorial Resistance to 5,10-Dideazatetrahydrofolic Acid in Cell Lines Derived from Human Lymphoblastic Leukemia CCRF-CEM

Giuseppe Pizzorno, Barbara A. Moroson, Arlene R. Cashmore, Orsolina Russello, Jennifer R. Mayer, John Galivan, Marlene A. Bunni, David G. Priest, and G. Peter Beardsley
Cancer Res 1995 55: 566-573. [Abstract] [PDF]  

N-[2-(2-Methyl-5-nitroimidazolyl)ethyl]-4-(2-nitroimidazolyl)butanamide (NSC 639862), a Bisnitroimidazole with Enhanced Selectivity as a Bioreductive Drug

John W. Moselen, Michael P. Hay, William A. Denny, and William R. Wilson
Cancer Res 1995 55: 574-580. [Abstract] [PDF]  

Intratumoral Activation and Enhanced Chemotherapeutic Effect of Oxazaphosphorines following Cytochrome P-450 Gene Transfer: Development of a Combined Chemotherapy/Cancer Gene Therapy Strategy

Ling Chen and David J. Waxman
Cancer Res 1995 55: 581-589. [Abstract] [PDF]  

Sensitization of Human Renal Cell Carcinoma Cells to cis-Diamminedichloroplatinum(II) by Anti-Interleukin 6 Monoclonal Antibody or Anti-Interleukin 6 Receptor Monoclonal Antibody

Youichi Mizutani, Benjamin Bonavida, Yasuo Koishihara, Ken-ichi Akamatsu, Yoshiyuki Ohsugi, and Osamu Yoshida
Cancer Res 1995 55: 590-596. [Abstract] [PDF]  

In Vivo Enhanced Antitumor Activity of Carmustine [N,N'-Bis(2-chloroethyl)-N-nitrosourea] by Simvastatin

Maurizio R. Soma, Roberta Baetta, M. Rita De Renzis, Giuliano Mazzini, Cecilia Davegna, Lorenzo Magrassi, Giorgio Butti, Stefano Pezzotta, Rodolfo Paoletti, and Remo Fumagalli
Cancer Res 1995 55: 597-602. [Abstract] [PDF]  

In Vivo Antitumor Activity of Two New Seven-substituted Water-soluble Camptothecin Analogues

David L. Emerson, Jeffrey M. Besterman, H. Roger Brown, Michael G. Evans, Peter P. Leitner, Michael J. Luzzio, Joel E. Shaffer, Daniel D. Sternbach, David Uehling, and Alain Vuong
Cancer Res 1995 55: 603-609. [Abstract] [PDF]  

Immunology:

Anti-CD54 (ICAM-1) Has Antitumor Activity in SCID Mice with Human Myeloma Cells

Yi-Wu Huang, James A. Richardson, and Ellen S. Vitetta
Cancer Res 1995 55: 610-616. [Abstract] [PDF]  

Role of Natural Killer Cells in Psychosocial Stressor-induced Changes in Mouse Mammary Tumor Growth

Gerald J. Rowse, Joanne Weinberg, and Joanne T. Emerman
Cancer Res 1995 55: 617-622. [Abstract] [PDF]  

Antibody-targeted Superantigens Induce Lysis of Major Histocompatibility Complex Class II-negative T-Cell Leukemia Lines

Johannes Ihle, Ursula Holzer, Frauke Krull, Mikael Dohlsten, Terje Kalland, Dietrich Niethammer, and Günther E. Dannecker
Cancer Res 1995 55: 623-628. [Abstract] [PDF]  

Molecular Biology and Genetics:

Negative Growth Control of HeLa Cells by Connexin Genes: Connexin Species Specificity

M. Mesnil, V. Krutovskikh, C. Piccoli, C. Elfgang, O. Traub, K. Willecke, and H. Yamasaki
Cancer Res 1995 55: 629-639. [Abstract] [PDF]  

Detection of Chromosomal Breakage in the 1cen-1q12 Region of Interphase Human Lymphocytes Using Multicolor Fluorescence in Situ Hybridization with Tandem DNA Probes

Doppalapudi S. Rupa, Leslie Hasegawa, and David A. Eastmond
Cancer Res 1995 55: 640-645. [Abstract] [PDF]  

p53 Abnormalities and Genomic Instability in Primary Human Breast Carcinomas

Jorunn E. Eyfjörd, Steinunn Thorlacius, Margret Steinarsdottir, Rut Valgardsdottir, Helga M. Ögmundsdottir, and Kesara Anamthawat-Jonsson
Cancer Res 1995 55: 646-651. [Abstract] [PDF]  

NM23-H1 and NM23-H2 Messenger RNA Abundance in Human Hepatocellular Carcinoma

Norio Iizuka, Masaaki Oka, Takafumi Noma, Atsushi Nakazawa, Kunitaka Hirose, and Takashi Suzuki
Cancer Res 1995 55: 652-657. [Abstract] [PDF]  

Mutations of the p53 Gene and p53 Protein Overexpression Are Associated with Sarcomatoid Transformation in Renal Cell Carcinomas

Hideaki Oda, Yoko Nakatsuru, and Takatoshi Ishikawa
Cancer Res 1995 55: 658-662. [Abstract] [PDF]  

Effect of a Mutation at Tyrosine 950 of the Insulin-like Growth Factor I Receptor on the Growth and Transformation of Cells

Masahiko Miura, Shiwei Li, and Renato Baserga
Cancer Res 1995 55: 663-667. [Abstract] [PDF]  

p53-independent Induction of WAF1/CIP1 in Human Leukemia Cells Is Correlated with Growth Arrest Accompanying Monocyte/Macrophage Differentiation

Wei Zhang, Luigi Grasso, Craig D. McClain, Anne M. Gambel, Ying Cha, Salvatore Travali, Albert B. Deisseroth, and W. Edward Mercer
Cancer Res 1995 55: 668-674. [Abstract] [PDF]  

Tumor Biology:

High Rates of Thioredoxin Secretion Correlate with Growth Arrest in Hepatoma Cells

Anna Rubartelli, Neris Bonifaci, and Roberto Sitia
Cancer Res 1995 55: 675-680. [Abstract] [PDF]  

Host Organ Specifically Determines Cancer Progression

Shinji Togo, Hiroshi Shimada, Tetsuro Kubota, A. R. Moossa, and Robert M. Hoffman
Cancer Res 1995 55: 681-684. [Abstract] [PDF]  

In Vivo Local Expansion of Clonal T Cell Subpopulations in Renal Cell Carcinoma

Catherine Gaudin, Pierre-Yves Dietrich, Sylvie Robache, Maryvonne Guillard, Bernard Escudier, Marie-Josée Terrier Lacombe, Anil Kumar, Frédéric Triebel, and Anne Caignard
Cancer Res 1995 55: 685-690. [Abstract] [PDF]  

Induction of Apoptosis by Sphingosine in Human Leukemic HL-60 Cells: A Possible Endogenous Modulator of Apoptotic DNA Fragmentation Occurring during Phorbol Ester-induced Differentiation

Hideki Ohta, Elizabeth A. Sweeney, Atsushi Masamune, Yutaka Yatomi, Sen-itiroh Hakomori, and Yasuyuki Igarashi
Cancer Res 1995 55: 691-697. [Abstract] [PDF]  

Solid Tumor Cells Express Functional "Tethered Ligand" Thrombin Receptor

M. Z. Wojtukiewicz, D. G. Tang, E. Ben-Josef, C. Renaud, D. A. Walz, and K. V. Honn
Cancer Res 1995 55: 698-704. [Abstract] [PDF]  

Meeting Reports:

Fifth Heidelberger Conference on Targets for Cancer Research: Prevention, Differentiation, and Selective Therapy

John S. Bertram
Cancer Res 1995 55: 705-709. [PDF]  

Genetic Polymorphism and Cancer Susceptibility: Fourteenth Sapporo Cancer Seminar

Frank J. Gonzalez
Cancer Res 1995 55: 710-715. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1995 55: 716-718. [PDF]  

Correction

Cancer Res 1995 55: 719 [PDF]  

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