Advances in Brief:

Chromosomal Mapping of Members of the cdc2 Family of Protein Kinases, cdk3, cdk6, PISSLRE, and PITALRE, and a cdk Inhibitor, p27^Kip1, to Regions Involved in Human Cancer

Florencia Bullrich, Timothy K. MacLachlan, Nianli Sang, Teresa Druck, Maria Luisa Veronese, Steven L. Allen, Nicholas Chiorazzi, Andrew Koff, Kay Heubner, Carlo M. Croce, and Antonio Giordano
Cancer Res 1995 55: 1199-1205. [Abstract] [PDF]  

Assignment of the Human p27^Kip1 Gene to 12p13 and Its Analysis in Leukemias

Jennifer A. Pietenpol, Stefan K. Bohlander, Yuko Sato, Nickolas Papadopoulos, Bo Liu, Cynthia Friedman, Barbara J. Trask, James M. Roberts, Kenneth W. Kinzler, Janet D. Rowley, and Bert Vogelstein
Cancer Res 1995 55: 1206-1210. [Abstract] [PDF]  

p27^Kip1: Chromosomal Mapping to 12p12–12p13.1 and Absence of Mutations in Human Tumors

M. Veronica Ponce-Castañeda, Mong-Hong Lee, Esther Latres, Kornelia Polyak, Louis Lacombe, Kate Montgomery, Susan Mathew, Kenneth Krauter, Joel Sheinfeld, Joan Massague, and Carlos Cordon-Cardo
Cancer Res 1995 55: 1211-1214. [Abstract] [PDF]  

Consistent Expression of an Epithelial Cell Adhesion Molecule (C-CAM) during Human Prostate Development and Loss of Expression in Prostate Cancer: Implication as a Tumor Suppressor

David I. Kleinerman, Patricia Troncoso, Sue-Hwa Lin, Louis L. Pisters, Edward R. Sherwood, Thomas Brooks, Andrew C. von Eschenbach, and Jer-Tsong Hsieh
Cancer Res 1995 55: 1215-1220. [Abstract] [PDF]  

Suppression of the Formation of Sister Chromatid Exchanges by Low Concentrations of Ginsenoside Rh₂ in Human Blood Lymphocytes

Jin Hua Zhu, Tatsuya Takeshita, Isao Kitagawa, and Kanehisa Morimoto
Cancer Res 1995 55: 1221-1223. [Abstract] [PDF]  

Glutathione Transferase (GSTM1) Null Genotype, Smoking, and Prevalence of Colorectal Adenomas

Henry J. Lin, Nicole M. Probst-Hensch, Sue A. Ingles, Chun-Ya Han, Bruce K. Lin, David B. Lee, Harold D. Frankl, Eric R. Lee, Matthew P. Longnecker, and Robert W. Haile
Cancer Res 1995 55: 1224-1226. [Abstract] [PDF]  

Neurofibromatosis Type 2 (NF2) Gene Is Somatically Mutated in Mesothelioma but not in Lung Cancer

Yoshitaka Sekido, Harvey I. Pass, Scott Bader, Daphne J. Y. Mew, Michael F. Christman, Adi F. Gazdar, and John D. Minna
Cancer Res 1995 55: 1227-1231. [Abstract] [PDF]  

Defective Repair of DNA Double-Strand Breaks and Chromosome Damage in Fibroblasts from a Radiosensitive Leukemia Patient

Christophe Badie, George Iliakis, Nicolas Foray, Ghazi Alsbeih, Gabriel E. Pantellias, Ryuichi Okayasu, Nge Cheong, Nicola S. Russell, Adrian C. Begg, Colin F. Arlett, and Edmond P. Malaise
Cancer Res 1995 55: 1232-1234. [Abstract] [PDF]  

DNA Strand Break Rejoining Defect in xrs-6 Is Complemented by Transfection with the Human Ku80 Gene

Gillian M. Ross, John J. Eady, Natasha P. Mithal, Cyd Bush, G. Gordon Steel, Penny A. Jeggo, and Trevor J. McMillan
Cancer Res 1995 55: 1235-1238. [Abstract] [PDF]  

Attenuation of the Antitumor Activity of 5-Fluorouracil by (R)-5-Fluoro-5,6-dihydrouracil

Thomas Spector, Shousong Cao, Youcef M. Rustum, Joan A. Harrington, and David J. T. Porter
Cancer Res 1995 55: 1239-1241. [Abstract] [PDF]  

Biochemistry and Biophysics:

Apoptosis Induced by Serum Deprivation of PC12 Cells Is Not Preceded by Growth Arrest and Can Occur at Each Phase of the Cell Cycle

Liora Lindenboim, Rochelle Diamond, Ellen Rothenberg, and Reuven Stein
Cancer Res 1995 55: 1242-1247. [Abstract] [PDF]  

In Vitro and in Vivo ³¹P Nuclear Magnetic Resonance Measurements of Metabolic Changes Post Radiation

Umar Mahmood, Alan A. Alfieri, Douglas Ballon, Frank Traganos, and Jason A. Koutcher
Cancer Res 1995 55: 1248-1254. [Abstract] [PDF]  

Changes in Topoisomerase I Levels and Localization during Myeloid Maturation in Vitro and in Vivo

Scott H. Kaufmann, Martin Charron, Philip J. Burke, and Judith E. Karp
Cancer Res 1995 55: 1255-1260. [Abstract] [PDF]  

Carcinogenesis:

Malignant and Nonmalignant Brain Tissues Differ in Their Messenger RNA Expression Patterns for ERCC1 and ERCC2

Meenakshi D. Dabholkar, Mitchel S. Berger, Justine A. Vionnet, Charles Egwuagu, John R. Silber, Jing Jie Yu, and Eddie Reed
Cancer Res 1995 55: 1261-1266. [Abstract] [PDF]  

Development of a Human Biomonitoring Assay Using Buccal Mucosa: Comparison of Smoking-related DNA Adducts in Mucosa versus Biopsies

Joanne G. Stone, Nigel J. Jones, Alan D. McGregor, and Raymond Waters
Cancer Res 1995 55: 1267-1270. [Abstract] [PDF]  

Cancer Induction by an Organic Arsenic Compound, Dimethylarsinic Acid (Cacodylic Acid), in F344/DuCrj Rats after Pretreatment with Five Carcinogens

Shinji Yamamoto, Yoshitsugu Konishi, Tsutomu Matsuda, Takashi Murai, Masa-Aki Shibata, Isao Matsui-Yuasa, Shuzo Otani, Koichi Kuroda, Ginji Endo, and Shoji Fukushima
Cancer Res 1995 55: 1271-1276. [Abstract] [PDF]  

Modifying Effects of Naturally Occurring Products on the Development of Colonic Aberrant Crypt Foci Induced by Azoxymethane in F344 Rats

Toshihiko Kawamori, Takuji Tanaka, Akira Hara, Johji Yamahara, and Hideki Mori
Cancer Res 1995 55: 1277-1282. [Abstract] [PDF]  

Mutagenesis by 8-Methoxypsoralen and 5-Methylangelicin Photoadducts in Mouse Fibroblasts: Mutations at Cross-Linkable Sites Induced by Monoadducts as well as Cross-Links

Edward J. Gunther, Toni M. Yeasky, Francis P. Gasparro, and Peter M. Glazer
Cancer Res 1995 55: 1283-1288. [Abstract] [PDF]  

Endocrinology:

Mammary and Submandibular Gland Epidermal Growth Factor Expression Is Reduced by Calorie Restriction

Robert W. Engelman, Una E. Owens, W. Guy Bradley, Noorbibi K. Day, and Robert A. Good
Cancer Res 1995 55: 1289-1295. [Abstract] [PDF]  

Epidemiology:

Incidence of Internal Cancers and Ingested Inorganic Arsenic: A Seven-Year Follow-up Study in Taiwan

Hung-Yi Chiou, Yu-Mei Hsueh, Kuen-Fu Liaw, Shan-Far Horng, Ming-Hsi Chiang, Yeong-Shiau Pu, Johnny Shinn-Nan Lin, Chun-Hsiung Huang, and Chien-Jen Chen
Cancer Res 1995 55: 1296-1300. [Abstract] [PDF]  

Vegetable Consumption, Serum Retinol Level, and Risk of Hepatocellular Carcinoma

Ming-Whei Yu, Hsiu-Hsing Hsieh, Wen-Harn Pan, Czau-Siung Yang, and Chien-Jen Chen
Cancer Res 1995 55: 1301-1305. [Abstract] [PDF]  

Experimental Therapeutics:

In Situ Cyclopentenyl Cytosine Infusion for the Treatment of Experimental Brain Tumors

John J. Viola, Riad Agbaria, Stuart Walbridge, Eric M. Oshiro, David G. Johns, James A. Kelley, Edward H. Oldfield, and Zvi Ram
Cancer Res 1995 55: 1306-1309. [Abstract] [PDF]  

Novel Antitumor Indolocarbazole Compound 6-N-Formylamino-12,13-dihydro-1,11-dihydroxy-13-(ß-D-glucopyranosyl)-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione (NB-506): Induction of Topoisomerase I-mediated DNA Cleavage and Mechanisms of Cell Line-selective Cytotoxicity

Tomoko Yoshinari, Mami Matsumoto, Hiroharu Arakawa, Hiromasa Okada, Kazuo Noguchi, Hiroyuki Suda, Akira Okura, and Susumu Nishimura
Cancer Res 1995 55: 1310-1315. [Abstract] [PDF]  

Novel Indolocarbazole Compound 6-N-Formylamino-12,13-dihydro-1,11-dihydroxy-13-(ß-D-glucopyranosyl)-5H-indolo[2,3-a]pyrro[3,4-c]carbazole-5,7(6H)-dione (NB-506): Its Potent Antitumor Activities in Mice

Hiroharu Arakawa, Tomoko Iguchi, Masashi Morita, Tomoko Yoshinari, Katsuhisa Kojiri, Hiroyuki Suda, Akira Okura, and Susumu Nishimura
Cancer Res 1995 55: 1316-1320. [Abstract] [PDF]  

In Vitro and in Vivo Cytotoxicity of an Anti-Osteosarcoma Immunotoxin Containing Pokeweed Antiviral Protein

Peter M. Anderson, Dorothea E. Meyers, Diane E. Hasz, Kristin Covalcuic, Daniel Saltzman, Chand Khanna, and Fatih M. Uckun
Cancer Res 1995 55: 1321-1327. [Abstract] [PDF]  

Overexpression of Ribonucleotide Reductase in Transfected Human KB Cells Increases Their Resistance to Hydroxyurea: M2 but not M1 Is Sufficient to Increase Resistance to Hydroxyurea in Transfected Cells

Bing-Sen Zhou, Nan-Yung Hsu, Bi-Cheng Pan, James H. Doroshow, and Yun Yen
Cancer Res 1995 55: 1328-1333. [Abstract] [PDF]  

Molecular Biology and Genetics:

Gains and Losses of DNA Sequences in Osteosarcomas by Comparative Genomic Hybridization

Maija Tarkkanen, Ritva Karhu, Anne Kallioniemi, Inkeri Elomaa, Aarne H. Kivioja, Juha Nevalainen, Tom Böhling, Erkki Karaharju, Eija Hyytinen, Sakari Knuutila, and Olli-P. Kallioniemi
Cancer Res 1995 55: 1334-1338. [Abstract] [PDF]  

Mutation at the Catalytic Site of Topoisomerase I in CEM/C2, a Human Leukemia Cell Line Resistant to Camptothecin

Akira Fujimori, W. Graydon Harker, Glenda Kohlhagen, Yuko Hoki, and Yves Pommier
Cancer Res 1995 55: 1339-1346. [Abstract] [PDF]  

Frequent Loss of Heterozygosity in Human Primary Squamous Cell and Colon Carcinomas at 7q31.1: Evidence for a Broad Range Tumor Suppressor Gene

Jean C. Zenklusen, Janet C. Thompson, Andres J. P. Klein-Szanto, and Claudio J. Conti
Cancer Res 1995 55: 1347-1350. [Abstract] [PDF]  

Replacement of the p16/CDKN2 Gene Suppresses Human Glioma Cell Growth

Wadih Arap, Ryo Nishikawa, Frank B. Furnari, Webster K. Cavenee, and H-J. Su Huang
Cancer Res 1995 55: 1351-1354. [Abstract] [PDF]  

Deletion Cartography around the D13S25 Locus in B Cell Chronic Lymphocytic Leukemia and Accurate Mapping of the Involved Tumor Suppressor Gene

M. C. Devilder, S. François, C. Bosic, A. Moreau, M. P. Mellerin, D. Le Paslier, R. Bataille, and J. P. Moisan
Cancer Res 1995 55: 1355-1357. [Abstract] [PDF]  

Tumor Biology:

Up-Regulation of Vascular Endothelial Growth Factor and Its Receptors in von Hippel-Lindau Disease-associated and Sporadic Hemangioblastomas

S. Wizigmann-Voos, G. Breier, W. Risau, and K. H. Plate
Cancer Res 1995 55: 1358-1364. [Abstract] [PDF]  

Aberrant Expression of p53 or the Epidermal Growth Factor Receptor Is Frequent in Early Bronchial Neoplasia, and Coexpression Precedes Squamous Cell Carcinoma Development

Valerie Rusch, David Klimstra, Irina Linkov, and Ethan Dmitrovsky
Cancer Res 1995 55: 1365-1372. [Abstract] [PDF]  

Substrate Balances across Colonic Carcinomas in Humans

Eggert Holm, Egbert Hagmüller, Ulrich Staedt, Gerwin Schlickeiser, Hans-Joachim Günther, Hans Leweling, Mehmet Tokus, and Hermann B. Kollmar
Cancer Res 1995 55: 1373-1378. [Abstract] [PDF]  

Alterations of c-myc Expression by Antisense Oligodeoxynucleotides Enhance the Induction of Apoptosis in HL-60 Cells

Shinya Kimura, Taira Maekawa, Kouichi Hirakawa, Akira Murakami, and Tatsuo Abe
Cancer Res 1995 55: 1379-1384. [Abstract] [PDF]  

Biphenotypic Sarcomas with Myogenic and Neural Differentiation Express the Ewing's Sarcoma EWS/FLI1 Fusion Gene

Poul H. B. Sorensen, Hiroyuki Shimada, Xian F. Liu, Jerian F. Lim, Gilles Thomas, and Timothy J. Triche
Cancer Res 1995 55: 1385-1392. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1995 55: 1393-1395. [PDF]  

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