Perspectives in Cancer Research:

DNA Methylation Errors and Cancer

Peter A. Jones
Cancer Res 1996 56: 2463-2467. [PDF]  

Advances in Brief:

Glucose Catabolism in Cancer Cells: Amplification of the Gene Encoding Type II Hexokinase

Annette Rempel, Saroj P. Mathupala, Constance A. Griffin, Anita L. Hawkins, and Peter L. Pedersen
Cancer Res 1996 56: 2468-2471. [Abstract] [PDF]  

Aberrant FHIT Transcripts in Merkel Cell Carcinoma

Gabriella Sozzi, Hansjuerg Alder, Silvana Tornielli, Valentina Corletto, Raffaele Baffa, Maria Luisa Veronese, Massimo Negrini, Silvana Pilotti, Marco A. Pierotti, Kay Huebner, and Carlo Maria Croce
Cancer Res 1996 56: 2472-2474. [Abstract] [PDF]  

Correlation of Chloroethylnitrosourea Resistance with ERCC-2 Expression in Human Tumor Cell Lines as Determined by Quantitative Competitive Polymerase Chain Reaction

Zhong-Ping Chen, Areti Malapetsa, Daniela Marcantonio, Gérard Mohr, Susan Brien, and Lawrence C. Panasci
Cancer Res 1996 56: 2475-2478. [Abstract] [PDF]  

Enhancement of Cytolytic T Lymphocyte Precursor Frequency in Melanoma Patients following Immunization with the MAGE-1 Peptide Loaded Antigen Presenting Cell-based Vaccine

Xueyou Hu, Nitya G. Chakraborty, Jonathan R. Sporn, Scott H. Kurtzman, M. T. Ergin, and Bijay Mukherji
Cancer Res 1996 56: 2479-2483. [Abstract] [PDF]  

Multiple Head and Neck Tumors: Evidence for a Common Clonal Origin

Gauri C. Bedi, William H. Westra, Edward Gabrielson, Wayne Koch, and David Sidransky
Cancer Res 1996 56: 2484-2487. [Abstract] [PDF]  

Genetic Progression Model for Head and Neck Cancer: Implications for Field Cancerization

Joseph Califano, Peter van der Riet, William Westra, Homaira Nawroz, Gary Clayman, Steven Piantadosi, Russell Corio, Daniel Lee, Benjamin Greenberg, Wayne Koch, and David Sidransky
Cancer Res 1996 56: 2488-2492. [Abstract] [PDF]  

Frequent Loss of the P16^INK4a Gene Product in Human Pituitary Tumors

Michael Woloschak, Aiqin Yu, Jiaqi Xiao, and Kalmon D. Post
Cancer Res 1996 56: 2493-2496. [Abstract] [PDF]  

Novel Germline p16 Mutation in Familial Malignant Melanoma in Southern Sweden

Åke Borg, Ulla Johansson, Oskar Johannsson, Sara Håkansson, Johan Westerdahl, Anna Måsbäck, Håkan Olsson, and Christian Ingvar
Cancer Res 1996 56: 2497-2500. [Abstract] [PDF]  

Frequent Microsatellite Instability in Epithelial Borderline Ovarian Tumors

Jacob Tangir, Nancy S. Loughridge, Ross S. Berkowitz, Michael G. Muto, Debra A. Bell, William R. Welch, and Samuel C. Mok
Cancer Res 1996 56: 2501-2505. [Abstract] [PDF]  

Deletion of a Nonconserved Region of Bcl-2 Confers a Novel Gain of Function: Suppression of Apoptosis with Concomitant Cell Proliferation

Erik J. Uhlmann, Cleta D'Sa-Eipper, T. Subramanian, Andrew J. Wagner, Nissim Hay, and G. Chinnadurai
Cancer Res 1996 56: 2506-2509. [Abstract] [PDF]  

Accumulation of p16^CDKN2A in Response to Ultraviolet Irradiation Correlates with a Late S-G₂-Phase Cell Cycle Delay

Xue Qing Wang, Brian G. Gabrielli, Amanda Milligan, Joanne L. Dickinson, Toni M. Antalis, and Kay A. O. Ellem
Cancer Res 1996 56: 2510-2514. [Abstract] [PDF]  

The Angiogenic Factor Midkine Is Expressed in Bladder Cancer, and Overexpression Correlates with a Poor Outcome in Patients with Invasive Cancers

Tim O'Brien, David Cranston, Susan Fuggle, Roy Bicknell, and Adrian L. Harris
Cancer Res 1996 56: 2515-2518. [Abstract] [PDF]  

DPC4, a Candidate Tumor Suppressor Gene, Is Altered Infrequently in Head and Neck Squamous Cell Carcinoma

Se Kyu Kim, Youhong Fan, Vali Papadimitrakopoulou, Gary Clayman, Walter N. Hittleman, Waun Ki Hong, Reuben Lotan, and Li Mao
Cancer Res 1996 56: 2519-2521. [Abstract] [PDF]  

Modulation of p53 Expression by Human Recombinant Interferon-2a Correlates with Abrogation of Cisplatin Resistance in a Human Melanoma Cell Line

Pamela A. Davol, Frederick A. Goulette, A. Raymond Frackelton, Jr., and James W. Darnowski
Cancer Res 1996 56: 2522-2526. [Abstract] [PDF]  

DPC4 Gene in Various Tumor Types

Mieke Schutte, Ralph H. Hruban, Lora Hedrick, Kathleen R. Cho, Gyongyi Molnar Nadasdy, Craig L. Weinstein, G. Steven Bova, William B. Isaacs, Paul Cairns, Homaira Nawroz, David Sidransky, Robert A. Casero, Jr., Paul S. Meltzer, Stephan A. Hahn, and Scott E. Kern
Cancer Res 1996 56: 2527-2530. [Abstract] [PDF]  

Amount of Interleukin 12 Available at the Tumor Site Is Critical for Tumor Regression

Mario P. Colombo, Maddalena Vagliani, Fabio Spreafico, Mariella Parenza, Claudia Chiodoni, Cecilia Melani, and Antonella Stoppacciaro
Cancer Res 1996 56: 2531-2534. [Abstract] [PDF]  

Processing of a Precursor of 72-Kilodalton Type IV Collagenase/Gelatinase A by a Recombinant Membrane-Type 1 Matrix Metalloproteinase

Takeshi Kinoshita, Hiroshi Sato, Takahisa Takino, Michiyasu Itoh, Toshifumi Akizawa, and Motoharu Seiki
Cancer Res 1996 56: 2535-2538. [Abstract] [PDF]  

Biochemistry and Biophysics:

Molecular Modeling of the Amino-Terminal Zinc Ring Domain of BRCA1

Rachelle J. Bienstock, Tom Darden, Roger Wiseman, Lee Pedersen, and J. Carl Barrett
Cancer Res 1996 56: 2539-2545. [Abstract] [PDF]  

Carcinogenesis:

Increase of a Type of Oxidative DNA Damage, 8-Hydroxyguanine, and Its Repair Activity in Human Leukocytes by Cigarette Smoking

Shinya Asami, Takeshi Hirano, Raizo Yamaguchi, Yoshiaki Tomioka, Hideaki Itoh, and Hiroshi Kasai
Cancer Res 1996 56: 2546-2549. [Abstract] [PDF]  

The Capability of Rat Colon Tissue Slices to Metabolize the Cooked-Food Carcinogen 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

Michael A. Malfatti, M. Suzanne Connors, Robert J. Mauthe, and James S. Felton
Cancer Res 1996 56: 2550-2555. [Abstract] [PDF]  

Cyclooxygenase-2 Overexpression and Tumor Formation Are Blocked by Sulindac in a Murine Model of Familial Adenomatous Polyposis

Susan K. Boolbol, Andrew J. Dannenberg, Amy Chadburn, Charles Martucci, XiaoJun Guo, John T. Ramonetti, Maria Abreu-Goris, Harold L. Newmark, Martin L. Lipkin, Jerome J. DeCosse, and Monica M. Bertagnolli
Cancer Res 1996 56: 2556-2560. [Abstract] [PDF]  

Endocrinology:

A Comparison between the Efficacy of Somatostatin Receptor Scintigraphy and That of in Situ Hybridization for Somatostatin Receptor Subtype 2 Messenger RNA to Predict Therapeutic Outcome in Carcinoid Patients

Eva Tiensuu Janson, Anders Gobl, Karl Mikael Kälkner, and Kjell Öberg
Cancer Res 1996 56: 2561-2565. [Abstract] [PDF]  

Experimental Therapeutics:

Engineered Stromal Layers and Continuous Flow Culture Enhance Multidrug Resistance Gene Transfer in Hematopoietic Progenitors

Francesco Bertolini, Manuela Battaglia, Chiara Corsini, Lorenza Lazzari, Davide Soligo, Carlo Zibera, and Karin Thalmeier
Cancer Res 1996 56: 2566-2572. [PDF]  

Characterization of Novel Human Leukemic Cell Lines Selected for Resistance to Merbarone, a Catalytic Inhibitor of DNA Topoisomerase II

Hiroki Kusumoto, Queen E. Rodgers, Friedrich Boege, Susana C. Raimondi, and William T. Beck
Cancer Res 1996 56: 2573-2583. [Abstract] [PDF]  

Increase of ß_III- and ß_IVa-Tubulin Isotypes in Human Prostate Carcinoma Cells as a Result of Estramustine Resistance

Sulabha Ranganathan, Dwayne W. Dexter, Christopher A. Benetatos, Andrew E. Chapman, Kenneth D. Tew, and Gary R. Hudes
Cancer Res 1996 56: 2584-2589. [Abstract] [PDF]  

Interleukin 2 (IL-2) Receptor Expression and Sensitivity to Diphtheria Fusion Toxin DAB₃₈₉IL-2 in Cultured Hematopoietic Cells

Gian G. Re, Cory Waters, Louis Poisson, Mark C. Willingham, Kazuo Sugamura, and Arthur E. Frankel
Cancer Res 1996 56: 2590-2595. [Abstract] [PDF]  

Inheritance of Susceptibility to Bleomycin-induced Pulmonary Fibrosis in the Mouse

Christina K. Haston, Christopher I. Amos, Terri M. King, and Elizabeth L. Travis
Cancer Res 1996 56: 2596-2601. [Abstract] [PDF]  

Antitumor Activity of 1 M Tegafur-0.4 M 5-Chloro-2,4-dihydroxypyridine-1 M Potassium Oxonate (S-1) against Human Colon Carcinoma Orthotopically Implanted into Nude Rats

Tetsuhiko Shirasaka, Koushi Nakano, Teiji Takechi, Hiroyasu Satake, Junji Uchida, Akio Fujioka, Hitoshi Saito, Hiroyuki Okabe, Kiyomi Oyama, Setsuo Takeda, Norio Unemi, and Masakazu Fukushima
Cancer Res 1996 56: 2602-2606. [Abstract] [PDF]  

Immunology:

Dendritic Epidermal T Cells in Ultraviolet-irradiated Skin Enhance Skin Tumor Growth by Inhibiting CD4⁺ T-Cell-mediated Immunity

Lois L. Cavanagh and Gary M. Halliday
Cancer Res 1996 56: 2607-2615. [Abstract] [PDF]  

Molecular Biology and Genetics:

Estrogen-induced Proto-Oncogene and Suppressor Gene Expression in the Hamster Kidney: Significance for Estrogen Carcinogenesis

Xiaoying Hou, Jonathan J. Li, Wenbiao Chen, and Sara Antonia Li
Cancer Res 1996 56: 2616-2620. [Abstract] [PDF]  

Inheritance of Abnormal Expression of SOS-like Response in Xeroderma Pigmentosum and Hereditary Cancer-prone Syndromes

Peter J. Abrahams, Ada Houweling, Paulien D. M. Cornelissen-Steijger, Fré Arwert, Fred H. Menko, Herbert M. Pinedo, Carrol Terleth, and Alex J. van der Eb
Cancer Res 1996 56: 2621-2625. [Abstract] [PDF]  

Resistance of a Variant ras-transformed Cell Line to Phenotypic Reversion by Farnesyl Transferase Inhibitors

George C. Prendergast, Joseph P. Davide, Peter F. Lebowitz, Robert Wechsler-Reya, and Nancy E. Kohl
Cancer Res 1996 56: 2626-2632. [Abstract] [PDF]  

Identification of Murine p120^cas Isoforms and Heterogeneous Expression of p120^cas Isoforms in Human Tumor Cell Lines

Yin-Yuan Mo and Albert B. Reynolds
Cancer Res 1996 56: 2633-2640. [Abstract] [PDF]  

PRG1: A Novel Early-Response Gene Transcriptionally Induced by Pituitary Adenylate Cyclase Activating Polypeptide in a Pancreatic Carcinoma Cell Line

Heiner Schäfer, Anna Trauzold, Erhard G. Siegel, Ulrich R. Fölsch, and Wolfgang E. Schmidt
Cancer Res 1996 56: 2641-2648. [Abstract] [PDF]  

In Vivo Ubiquitination and Proteasome-mediated Degradation of p53

Carl G. Maki, Jon M. Huibregtse, and Peter M. Howley
Cancer Res 1996 56: 2649-2654. [Abstract] [PDF]  

Tumor Biology:

Biallelic Alterations of Both ETV6 and CDKN1B Genes in a t(12;21) Childhood Acute Lymphoblastic Leukemia Case

Iwona Wlodarska, Mathijs Baens, Pieter Peeters, Jeroen Aerssens, Cristina Mecucci, Penelope Brock, Peter Marynen, and Herman Van den Berghe
Cancer Res 1996 56: 2655-2661. [Abstract] [PDF]  

Augmentation of Tumor Metastasis by Platelet-activating Factor

Suhn-Young Im, Hyun-Mi Ko, Yoo-Seung Ko, Jung-Woo Kim, Hern-Ku Lee, Tai-You Ha, Hwanghee Blaise Lee, Sang-Jin Oh, Suk Bai, Ki-Chul Chung, Young-Bo Lee, Hyen-Sam Kang, and Soon-Bai Chun
Cancer Res 1996 56: 2662-2665. [Abstract] [PDF]  

Epidermal Growth Factor-Responsive and -Refractory Carcinomas Initiated with N-methyl-N-nitrosourea in Rat Urinary Bladder

Kiyohide Fujimoto, Yoshinori Tanaka, Alfred Rademaker, and Ryoichi Oyasu
Cancer Res 1996 56: 2666-2670. [Abstract] [PDF]  

Extent of Tumor Vascularization Correlates with Prognosis and Hematogenous Metastasis in Gastric Carcinomas

Nobuhiko Tanigawa, Hirokazu Amaya, Mitsuyoshi Matsumura, Takumi Shimomatsuya, Tetsuya Horiuchi, Ryusuke Muraoka, and Masayuki Iki
Cancer Res 1996 56: 2671-2676. [Abstract] [PDF]  

Letters to the Editor:

Correspondence re: J. A. Knol et al., Incorporation of 5-Bromo-2'-deoxyuridine into Colorectal Liver Metastases and Liver in Patients Receiving a 7-Day Hepatic Arterial Infusion. Cancer Res., 55: 3687–3691, 1995

Jerry M. Collins, Raymond W. Klecker, Alfred E. Chang, and Timothy J. Kinsella
Cancer Res 1996 56: 2677 [PDF]  

Correspondence re: J. A. Knol et al., Incorporation of 5-Bromo-2'-deoxyuridine into Colorectal Liver Metastases and Liver in Patients Receiving a 7-Day Hepatic Arterial Infusion. Cancer Res., 55: 3687–3691, 1995—Reply

James A. Knol, Theodore S. Lawrence, William D. Ensminger, Philip L. Stetson, Suzette C. Walker, Zhoamin Yang, Susan DeRemer, and John M. Robertson
Cancer Res 1996 56: 2677-2678. [PDF]  

Articles:

Announcements

Cancer Res 1996 56: 2679-2681. [PDF]  

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