Advances in Brief:

N-Acetyltransferase Expression and Metabolic Activation of the Food-derived Heterocyclic Amines in the Human Mammary Gland

Nakissa Sadrieh, Cindy D. Davis, and Elizabeth G. Snyderwine
Cancer Res 1996 56: 2683-2687. [Abstract] [PDF]  

An Integrated Microsatellite Length Analysis Using an Automated Fluorescent DNA Sequencer

Yasushi Toh, Eiji Oki, Shinya Oda, Masaaki Tomoda, Shinichi Tomisaki, Yuji Ichiyoshi, Shinji Ohno, and Keizo Sugimachi
Cancer Res 1996 56: 2688-2691. [Abstract] [PDF]  

Metabolic Phenotypes of Retinoic Acid and the Risk of Lung Cancer

James R. Rigas, Vincent A. Miller, Zuo-Feng Zhang, David S. Klimstra, William P. Tong, Mark G. Kris, and Raymond P. Warrell, Jr.
Cancer Res 1996 56: 2692-2696. [Abstract] [PDF]  

Herpes Simplex Virus Thymidine Kinase/Ganciclovir-mediated Apoptotic Death of Bystander Cells

Wolfgang Hamel, Lucia Magnelli, Vincenzo P. Chiarugi, and Mark A. Israel
Cancer Res 1996 56: 2697-2702. [Abstract] [PDF]  

Increased Angiogenin Expression in Pancreatic Cancer Is Related to Cancer Aggressiveness

Shouji Shimoyama, Frank Gansauge, Susanne Gansauge, Giovanni Negri, Takeshi Oohara, and Hans G. Beger
Cancer Res 1996 56: 2703-2706. [Abstract] [PDF]  

Membrane-Type Matrix Metalloproteinase 1 Is a Gelatinolytic Enzyme and Is Secreted in a Complex with Tissue Inhibitor of Metalloproteinases 2

Kazushi Imai, Eiko Ohuchi, Takanori Aoki, Hidehiro Nomura, Yutaka Fujii, Hiroshi Sato, Motoharu Seiki, and Yasunori Okada
Cancer Res 1996 56: 2707-2710. [Abstract] [PDF]  

Protein Kinase C Inhibition Induces Apoptosis and Ceramide Production through Activation of a Neutral Sphingomyelinase

Steven J. Chmura, Edwardine Nodzenski, Ralph R. Weichselbaum, and Jose Quintans
Cancer Res 1996 56: 2711-2714. [Abstract] [PDF]  

Trans-Dominant Inhibition of Poly(ADP-ribosyl)ation Potentiates Carcinogen-induced Gene Amplification in SV40-transformed Chinese Hamster Cells

Jan-Heiner Küpper, Marcus Müller, and Alexander Bürkle
Cancer Res 1996 56: 2715-2717. [Abstract] [PDF]  

Somatic in Vivo Alterations of the DPC4 Gene at 18q21 in Human Lung Cancers

Masaaki Nagatake, Yukihiro Takagi, Hirotaka Osada, Kosaku Uchida, Tetsuya Mitsudomi, Shigetoyo Saji, Kaoru Shimokata, Toshitada Takahashi, and Takashi Takahashi
Cancer Res 1996 56: 2718-2720. [Abstract] [PDF]  

Hypermethylation of the p16 Gene in Nasopharyngeal Carcinoma

Kwok-Wai Lo, Siu-Tim Cheung, Sing-Fai Leung, Andrew van Hasselt, Yuen-Shan Tsang, Ko-Fung Mak, Yuk-Fei Chung, John K. S. Woo, Joseph C. K. Lee, and Dolly P. Huang
Cancer Res 1996 56: 2721-2725. [Abstract] [PDF]  

The ATM Gene and Susceptibility to Breast Cancer: Analysis of 38 Breast Tumors Reveals No Evidence for Mutation

Igor Vorechovsky, Debora Rasio, Liping Luo, Carmen Monaco, Lennart Hammarström, A. David B. Webster, Jan Zaloudik, Giuseppe Barbanti-Brodano, Michael James, Giandomenico Russo, Carlo M. Croce, and Massimo Negrini
Cancer Res 1996 56: 2726-2732. [Abstract] [PDF]  

Detection of a Mutator Phenotype in Cancer Cells by Inter-Alu Polymerase Chain Reaction

Maja Krajinovic, Chantal Richer, Damian Labuda, and Daniel Sinnett
Cancer Res 1996 56: 2733-2737. [Abstract] [PDF]  

Mutations of the BRCA2 Gene in Ovarian Carcinomas

Hiroyuki Takahashi, Hsiu-Chiang Chiu, Christina A. Bandera, Kian Behbakht, Paul C. Liu, Fergus J. Couch, Barbara L. Weber, Virginia A. LiVolsi, Masakuni Furusato, Beth Ann Rebane, Annmarie Cardonick, Ivor Benjamin, Mark A. Morgan, Stephanie A. King, John J. Mikuta, Stephen C. Rubin, and Jeff Boyd
Cancer Res 1996 56: 2738-2741. [Abstract] [PDF]  

IA-2, a Transmembrane Protein Tyrosine Phosphatase, Is Expressed in Human Lung Cancer Cell Lines with Neuroendocrine Phenotype

Hong Xie, Abner L. Notkins, and Michael S. Lan
Cancer Res 1996 56: 2742-2744. [Abstract] [PDF]  

Inhibition of Fatty Acid Synthesis Induces Programmed Cell Death in Human Breast Cancer Cells

Ellen S. Pizer, Christian Jackisch, Fawn D. Wood, Gary R. Pasternack, Nancy E. Davidson, and Francis P. Kuhajda
Cancer Res 1996 56: 2745-2747. [Abstract] [PDF]  

Wild-Type p53 Renders Mouse Astrocytes Resistant to 1,3-Bis(2-chloroethyl)-1-nitrosourea despite the Absence of a p53-dependent Cell Cycle Arrest

Catherine L. Nutt, Ann F. Chambers, and J. Gregory Cairncross
Cancer Res 1996 56: 2748-2751. [Abstract] [PDF]  

Biochemistry and Biophysics:

Human Colorectal Carcinomas Specifically Accumulate M_r 42,000 Ubiquitinconjugated Cytokeratin 8 Fragments

Hideki Nishibori, Yoshihiro Matsuno, Keiichi Iwaya, Takuya Osada, Nobuko Kubomura, Akihiro Iwamatsu, Hiroaki Kohno, Seiji Sato, Masaki Kitajima, and Setsuo Hirohashi
Cancer Res 1996 56: 2752-2757. [Abstract] [PDF]  

Regulation of Carbonyl-reducing Enzymes in Rat Liver by Chemoprotectors

Elizabeth M. Ellis, David J. Judah, Gordon E. Neal, Tania O'Connor, and John D. Hayes
Cancer Res 1996 56: 2758-2766. [Abstract] [PDF]  

Carcinogenesis:

Chemopreventive Effects of 24R,25-Dihydroxyvitamin D₃, a Vitamin D₃ Derivative, on Glandular Stomach Carcinogenesis Induced in Rats by N-Methyl-N'-nitro-N-nitrosoguanidine and Sodium Chloride

Shinichiro Ikezaki, Akiyoshi Nishikawa, Fumio Furukawa, Zen-yo Tanakamaru, Hyoung-Chin Kim, Hideki Mori, and Michihito Takahashi
Cancer Res 1996 56: 2767-2770. [Abstract] [PDF]  

Clinical Investigations:

Manganese Superoxide Dismutase Expression Correlates with p53 Status and Local Recurrence of Cervical Carcinoma Treated with Radiation Therapy

Takashi Nakano, Kuniyuki Oka, and Naoyuki Taniguchi
Cancer Res 1996 56: 2771-2775. [Abstract] [PDF]  

Relationship between Serum Levels of Interleukin 6, Various Disease Parameters, and Malnutrition in Patients with Esophageal Squamous Cell Carcinoma

Masaaki Oka, Kohtaro Yamamoto, Mutsuo Takahashi, Michinori Hakozaki, Toshihiro Abe, Norio Iizuka, Shoichi Hazama, Katsutoshi Hirazawa, Hiroto Hayashi, Akira Tangoku, Kunitaka Hirose, Tokuhiro Ishihara, and Takashi Suzuki
Cancer Res 1996 56: 2776-2780. [Abstract] [PDF]  

Endocrinology:

Repression of the Insulin Receptor Promoter by the Tumor Suppressor Gene Product p53: A Possible Mechanism for Receptor Overexpression in Breast Cancer

Nicholas J. G. Webster, Jamie L. Resnik, Donna B. Reichart, Brian Strauss, Martin Haas, and B. Lynn Seely
Cancer Res 1996 56: 2781-2788. [Abstract] [PDF]  

Antiestrogen Potentiation of Antiproliferative Effects of Vitamin D₃ Analogues in Breast Cancer Cells

Cheryl D. Love-Schimenti, David F. C. Gibson, Anita V. Ratnam, and Daniel D. Bikle
Cancer Res 1996 56: 2789-2794. [Abstract] [PDF]  

Experimental Therapeutics:

Identification of Topoisomerase I as the Cytotoxic Target of the Protoberberine Alkaloid Coralyne

Barbara Gatto, Marilyn M. Sanders, Chiang Yu, Hong-Yan Wu, Darshan Makhey, Edmond J. LaVoie, and Leroy F. Liu
Cancer Res 1996 56: 2795-2800. [Abstract] [PDF]  

Reduction of Tumor Hypoxia and Inhibition of DNA Repair by Nicotinamide after Irradiation of SCCVII Murine Tumors and Normal Tissues

Haihua Zheng and Peggy L. Olive
Cancer Res 1996 56: 2801-2808. [Abstract] [PDF]  

Antitumor Activity of a Novel Podophyllotoxin Derivative (TOP-53) against Lung Cancer and Lung Metastatic Cancer

Teruhiro Utsugi, Jiro Shibata, Yoshikazu Sugimoto, Kumio Aoyagi, Konstanty Wierzba, Takashi Kobunai, Tadafumi Terada, Tomoko Oh-hara, Takashi Tsuruo, and Yuji Yamada
Cancer Res 1996 56: 2809-2814. [Abstract] [PDF]  

Control of Lymphatic and Hematogenous Metastasis of a Rat Mammary Carcinoma by the Matrix Metalloproteinas Inhibitor Batimastat (BB-94)

Suzanne A. Eccles, Gary M. Box, William J. Court, Elisabeth A. Bone, Wayne Thomas, and Peter D. Brown
Cancer Res 1996 56: 2815-2822. [Abstract] [PDF]  

DT-Diaphorase as a Critical Determinant of Sensitivity to Mitomycin C in Human Colon and Gastric Carcinoma Cell Lines

Koji Mikami, Mikihiko Naito, Akihiro Tomida, Manabu Yamada, Takayuki Sirakusa, and Takashi Tsuruo
Cancer Res 1996 56: 2823-2826. [Abstract] [PDF]  

Immunology:

Deglycosylation of Serum Vitamin D₃-binding Protein Leads to Immunosuppression in Cancer Patients

Nobuto Yamamoto, Venkateswara R. Naraparaju, and Sucha O. Asbell
Cancer Res 1996 56: 2827-2831. [Abstract] [PDF]  

Costimulation Enhances the Active Immunotherapy Effect of Recombinant Anticancer Vaccines

Ronald S. Chamberlain, Miles W. Carroll, Vincenzo Bronte, Patrick Hwu, Steven Warren, James C. Yang, Michael Nishimura, Bernard Moss, Steven A. Rosenberg, and Nicholas P. Restifo
Cancer Res 1996 56: 2832-2836. [Abstract] [PDF]  

Molecular Biology and Genetics:

Presence of Urokinase in Serum-free Primary Rat Hepatocyte Cultures and Its Role in Activating Hepatocyte Growth Factor

Wendy M. Mars, Tae-Hyoung Kim, Donna Beer Stolz, Meng-Lun Liu, and George K. Michalopoulos
Cancer Res 1996 56: 2837-2843. [Abstract] [PDF]  

Tumor Biology:

High Expression of Ganglioside -2,8-Sialyltransferase (G_D3 Synthase) Gene in Adult T-Cell Leukemia Cells Unrelated to the Gene Expression of Human T-Lymphotropic Virus Type I

Masahiko Okada, Keiko Furukawa, Shuji Yamashiro, Yasuaki Yamada, Masashi Haraguchi, Keizo Horibe, Koji Kato, Yoshiro Tsuji, Hiroshi Shiku, and Koichi Furukawa
Cancer Res 1996 56: 2844-2848. [Abstract] [PDF]  

Immunohistochemical Analysis of in Vivo Patterns of Bak Expression, a Proapoptotic Member of the Bcl-2 Protein Family

Stanislaw Krajewski, Maryla Krajewska, and John C. Reed
Cancer Res 1996 56: 2849-2855. [Abstract] [PDF]  

Neurotrophin Stimulation of Human Melanoma Cell Invasion: Selected Enhancement of Heparanase Activity and Heparanase Degradation of Specific Heparan Sulfate Subpopulations

Dario Marchetti, David J. McQuillan, William C. Spohn, Dan D. Carson, and Garth L. Nicolson
Cancer Res 1996 56: 2856-2863. [Abstract] [PDF]  

Manganese-containing Superoxide Dismutase Overexpression Causes Phenotypic Reversion in SV40-transformed Human Lung Fibroblasts

Tao Yan, Larry W. Oberley, Weixiong Zhong, and Daret K. St. Clair
Cancer Res 1996 56: 2864-2871. [Abstract] [PDF]  

Suppression of a Human Colon Cancer Cell Line by Introduction of an Exogenous NF1 Gene

Ying Li and Ray White
Cancer Res 1996 56: 2872-2876. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1996 56: 2877-2879. [PDF]  

Erratum

Cancer Res 1996 56: 2879 [PDF]  

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