Advances in Brief:

Identification of a Novel Protein (VBP-1) Binding to the von Hippel-Lindau (VHL) Tumor Suppressor Gene Product

Haruo Tsuchiya, Tokuhiro Iseda, and Okio Hino
Cancer Res 1996 56: 2881-2885. [Abstract] [PDF]  

Elevated p16 at Senescence and Loss of p16 at Immortalization in Human Papillomavirus 16 E6, but not E7, Transformed Human Uroepithelial Cells

Catherine A. Reznikoff, Thomas R. Yeager, Cassandra D. Belair, Elena Savelieva, Jairaj A. Puthenveettil, and Walter M. Stadler
Cancer Res 1996 56: 2886-2890. [Abstract] [PDF]  

Overexpression of Tissue Inhibitor of Metalloproteinases-2 by Retroviral-mediated Gene Transfer in Vivo Inhibits Tumor Growth and Invasion

Suzan Imren, Donald B. Kohn, Hiroyuki Shimada, Laurence Blavier, and Yves A. DeClerck
Cancer Res 1996 56: 2891-2895. [Abstract] [PDF]  

Inability of Low- or High-Fat Diet to Modulate Late Stages of Colon Carcinogenesis in Sprague-Dawley Rats

Ranjana P. Bird, Kaiqi Yao, Cathy M. Lasko, and Carolyn K. Good
Cancer Res 1996 56: 2896-2899. [Abstract] [PDF]  

Microvessel Count Predicts Survival in Uveal Melanoma

Alexander J. E. Foss, Robert A. Alexander, Lee W. Jefferies, John L. Hungerford, Adrian L. Harris, and Susan Lightman
Cancer Res 1996 56: 2900-2903. [Abstract] [PDF]  

H19 Gene Overexpression in Atypical Multidrug-resistant Cells Associated with Expression of a 95-Kilodalton Membrane Glycoprotein

L. Austin Doyle, Weidong Yang, Arun K. Rishi, Yongming Gao, and Douglas D. Ross
Cancer Res 1996 56: 2904-2907. [Abstract] [PDF]  

Evidence for an Important Role of Neutrophils in the Efficacy of Photodynamic Therapy in Vivo

Wil J. A. de Vree, Maria C. Essers, Henriëtte S. de Bruijn, Willem M. Star, Johan F. Koster, and Wim Sluiter
Cancer Res 1996 56: 2908-2911. [Abstract] [PDF]  

Detection of Germline BRCA1 Mutations in Breast Cancer Patients by Quantitative Messenger RNA in Situ Hybridization

Tommi Kainu, Juha Kononen, Oskar Johansson, Håkan Olsson, Åke Borg, and Jorma Isola
Cancer Res 1996 56: 2912-2915. [Abstract] [PDF]  

High-Density Marker Analysis of 11p15.5 in Non-Small Cell Lung Carcinomas Reveals Allelic Deletion of One Shared and One Distinct Region When Compared to Breast Carcinomas

Yen K. Tran and Irene F. Newsham
Cancer Res 1996 56: 2916-2921. [Abstract] [PDF]  

MSH2 Deficiency Contributes to Accelerated APC-mediated Intestinal Tumorigenesis

Armin H. Reitmair, Jian-Chun Cai, Matthew Bjerknes, Mark Redston, Hazel Cheng, Molly T. L. Pind, Kazy Hay, Angela Mitri, Bharati V. Bapat, Tak W. Mak, and Steven Gallinger
Cancer Res 1996 56: 2922-2926. [Abstract] [PDF]  

Allelic Losses at Chromosomes 1p, 2p, 6p, 10p, 13q, 17p, and 21q Significantly Correlate with the Chromophobe Subtype of Renal Cell Carcinoma

Rüdiger F. Schwerdtle, Stephan Störkel, Christine Neuhaus, Hiltrud Brauch, Eberhard Weidt, Wallburgis Brenner, Rudolf Hohenfellner, Christoph Huber, and Hans-Jochen Decker
Cancer Res 1996 56: 2927-2930. [Abstract] [PDF]  

Increased Sensitivity to Cisplatin by nm23-transfected Tumor Cell Lines

Amy W. Ferguson, Ursula Flatow, Nicholas J. MacDonald, Florence Larminat, Villhelm A. Bohr, and Patricia S. Steeg
Cancer Res 1996 56: 2931-2935. [Abstract] [PDF]  

Evaluation of the FHIT Gene in Colorectal Cancers

Sam Thiagalingam, Nikolai A. Lisitsyn, Masaaki Hamaguchi, Michael H. Wigler, James K. V. Willson, Sanford D. Markowitz, Frederick S. Leach, Kenneth W. Kinzler, and Bert Vogelstein
Cancer Res 1996 56: 2936-2939. [Abstract] [PDF]  

p53-dependent Cell Cycle Arrests Are Preserved in DNA-activated Protein Kinase-deficient Mouse Fibroblasts

Li-chun Huang, Kristie C. Clarkin, and Geoffrey M. Wahl
Cancer Res 1996 56: 2940-2944. [Abstract] [PDF]  

Accelerated Degradation of PML-Retinoic Acid Receptor (PML-RARA) Oncoprotein by All-trans-Retinoic Acid in Acute Promyelocytic Leukemia: Possible Role of the Proteasome Pathway

Hitoshi Yoshida, Kunio Kitamura, Keiji Tanaka, Satoshi Omura, Toshiaki Miyazaki, Takahisa Hachiya, Ryuzo Ohno, and Tomoki Naoe
Cancer Res 1996 56: 2945-2948. [Abstract] [PDF]  

Fetal- and Tumor-specific Regulation of Growth Hormone Receptor Messenger RNA Expression in Human Liver

George Zogopoulos, Steffen Albrecht, Torsten Pietsch, Lesley Alpert, Dietrich von Schweinitz, Yves Lefèbvre, and Cynthia G. Goodyer
Cancer Res 1996 56: 2949-2953. [Abstract] [PDF]  

Phenethyl Isothiocyanate, A Natural Chemopreventive Agent, Activates c-Jun N-Terminal Kinase 1

Rong Yu, Jie-Jun Jiao, Jauh-Lin Duh, Tse-Hua Tan, and A-N. Tony Kong
Cancer Res 1996 56: 2954-2959. [Abstract] [PDF]  

Tumor Cell Autocrine Motility Factor Is the Neuroleukin/Phosphohexose Isomerase Polypeptide

Hideomi Watanabe, Kenji Takehana, Masayo Date, Tetsuya Shinozaki, and Avraham Raz
Cancer Res 1996 56: 2960-2963. [Abstract] [PDF]  

Biochemistry and Biophysics:

Metabolic Characterization of Human Soft Tissue Sarcomas in Vivo and in Vitro Using Proton-decoupled Phosphorus Magnetic Resonance Spectroscopy

Chun-Wei Li, Annette C. Kuesel, Kristin A. Padavic-Shaller, Joseph Murphy-Boesch, Burton L. Eisenberg, Richard G. Schmidt, Reinhard W. von Roemeling, Arthur S. Patchefsky, Truman R. Brown, and William G. Negendank
Cancer Res 1996 56: 2964-2972. [Abstract] [PDF]  

Flavopiridol Induces G₁ Arrest with Inhibition of Cyclin-dependent Kinase (CDK) 2 and CDK4 in Human Breast Carcinoma Cells

Bradley A. Carlson, Marja M. Dubay, Edward A. Sausville, Leonardo Brizuela, and Peter J. Worland
Cancer Res 1996 56: 2973-2978. [Abstract] [PDF]  

Carcinogenesis:

Activation of Chemically Diverse Procarcinogens by Human Cytochrome P-450 1B1

Tsutomu Shimada, Carrie L. Hayes, Hiroshi Yamazaki, Shantu Amin, Stephen S. Hecht, F. Peter Guengerich, and Thomas R. Sutter
Cancer Res 1996 56: 2979-2984. [Abstract] [PDF]  

Karyotypic Changes in a Multistage Model of Chemical Hepatocarcinogenesis in the Rat

Linda Sargent, Yvonne Dragan, Yi-Hua Xu, Gerald Sattler, John Wiley, and Henry C. Pitot
Cancer Res 1996 56: 2985-2991. [Abstract] [PDF]  

Cytogenetic Analysis of Three Rat Liver Epithelial Cell Lines (WBneo, WBHa-ras, and WBrasIIa) and Correlation of an Early Chromosomal Alteration with Insulin-like Growth Factor II Expression

Linda Sargent, Yvonne P. Dragan, Karlee Babcock, John Wiley, James Klaunig, and Henry C. Pitot
Cancer Res 1996 56: 2992-2997. [Abstract] [PDF]  

p53-independent Apoptosis during Mammary Tumor Progression in C3(1)/SV40 Large T Antigen Transgenic Mice: Suppression of Apoptosis during the Transition from Preneoplasia to Carcinoma

Masa-Aki Shibata, Ioanna G. Maroulakou, Cheryl L. Jorcyk, Lyn G. Gold, Jerrold M. Ward, and Jeffrey E. Green
Cancer Res 1996 56: 2998-3003. [Abstract] [PDF]  

Clinical Investigations:

Expression of Vascular Permeability Factor/Vascular Endothelial Growth Factor in Human Hepatocellular Carcinoma

Kunio Suzuki, Norio Hayashi, Yasuhide Miyamoto, Masato Yamamoto, Kazuyoshi Ohkawa, Yoshiki Ito, Yutaka Sasaki, Yumiko Yamaguchi, Hideyuki Nakase, Katsuhisa Noda, Norihiro Enomoto, Keiichi Arai, Yukinori Yamada, Harumasa Yoshihara, Takashi Tujimura, Kiyoshi Kawano, Kiyoshi Yoshikawa, and Takenobu Kamada
Cancer Res 1996 56: 3004-3009. [Abstract] [PDF]  

Methods to Detect P-Glycoprotein-associated Multidrug Resistance in Patients' Tumors: Consensus Recommendations

William T. Beck, Thomas M. Grogan, Cheryl L. Willman, Carlos Cordon-Cardo, David M. Parham, John F. Kuttesch, Michael Andreeff, Susan E. Bates, Costan W. Berard, James M. Boyett, Nathalie A. Brophy, Henk J. Broxterman, Helen S. L. Chan, William S. Dalton, Manfred Dietel, Antonio T. Fojo, Randy D. Gascoyne, David Head, Peter J. Houghton, Deo Kumar Srivastava, Manfred Lehnert, Catherine P. Leith, Elisabeth Paietta, Zlatko P. Pavelic, Lisa Rimsza, Igor B. Roninson, Branimir I. Sikic, Peter R. Twentyman, Roger Warnke, and Ronald Weinstein
Cancer Res 1996 56: 3010-3020. [Abstract] [PDF]  

Phase I Clinical Trial with a Human Major Histocompatibility Complex Nonrestricted Cytotoxic T-Cell Line (TALL-104) in Dogs with Advanced Tumors

Alessandra Cesano, Sophie Visonneau, K. Ann Jeglum, Jennifer Owen, Kim Wilkinson, Kathy Carner, Laurie Reese, and Daniela Santoli
Cancer Res 1996 56: 3021-3029. [Abstract] [PDF]  

Experimental Therapeutics:

Deoxynucleotide Pool Depletion and Sustained Inhibition of Ribonucleotide Reductase and DNA Synthesis after Treatment of Human Lymphoblastoid Cells with 2-Chloro-9-(2-deoxy-2-fluoro-ß-D-arabinofuranosyl)adenine

Kevin Chunxi Xie and William Plunkett
Cancer Res 1996 56: 3030-3037. [Abstract] [PDF]  

Antitumor Effects of an Adenovirus Expressing Antisense Insulin-like Growth Factor I Receptor on Human Lung Cancer Cell Lines

Choon-Taek Lee, Shan Wu, Dmitry Gabrilovich, Hailei Chen, Sorena Nadaf-Rahrov, Ilja F. Ciernik, and David P. Carbone
Cancer Res 1996 56: 3038-3041. [Abstract] [PDF]  

CWR22: The First Human Prostate Cancer Xenograft with Strongly Androgen-dependent and Relapsed Strains Both in Vivo and in Soft Agar

Moolky Nagabhushan, Casey M. Miller, Theresa P. Pretlow, Joseph M. Giaconia, Nancy L. Edgehouse, Stuart Schwartz, Hsing-Jien Kung, Ralph W. de Vere White, Paul H. Gumerlock, Martin I. Resnick, Saeid B. Amini, and Thomas G. Pretlow
Cancer Res 1996 56: 3042-3046. [Abstract] [PDF]  

Adenovirus-mediated Transfer of a Wild-Type p53 Gene and Induction of Apoptosis in Cervical Cancer

Katsuyuki Hamada, Ramon Alemany, Wei-Wei Zhang, Walter N. Hittelman, Reuben Lotan, Jack A. Roth, and Michele Follen Mitchell
Cancer Res 1996 56: 3047-3054. [Abstract] [PDF]  

Immunology:

Minibody: A Novel Engineered Anti-Carcinoembryonic Antigen Antibody Fragment (Single-Chain Fv-C_H3) Which Exhibits Rapid, High-Level Targeting of Xenografts

Shi-zhen Hu, Louise Shively, Andrew Raubitschek, Mark Sherman, Lawrence E. Williams, Jeffrey Y. C. Wong, John E. Shively, and Anna M. Wu
Cancer Res 1996 56: 3055-3061. [Abstract] [PDF]  

Processing of Antibodies Bound to B-Cell Lymphomas and Other Hematological Malignancies

Rafik Hanna, Gaik Lin Ong, and M. Jules Mattes
Cancer Res 1996 56: 3062-3068. [Abstract] [PDF]  

Synthesis of -Galactosyl Epitopes by Recombinant 1,3Galactosyltransferase for Opsonization of Human Tumor Cell Vaccines by Anti-Galactose

Denise C. LaTemple, Timothy R. Henion, Farvardin Anaraki, and Uri Galili
Cancer Res 1996 56: 3069-3074. [Abstract] [PDF]  

Molecular Biology and Genetics:

Multiple Features of Advanced Melanoma Recapitulated in Tumorigenic Variants of Early Stage (Radial Growth Phase) Human Melanoma Cell Lines: Evidence for a Dominant Phenotype

Maria Rosa Bani, Janusz Rak, Dena Adachi, Rodney Wiltshire, Jeffrey M. Trent, Robert S. Kerbel, and Yaacov Ben-David
Cancer Res 1996 56: 3075-3086. [Abstract] [PDF]  

Loss of DNA Mismatch Repair in Acquired Resistance to Cisplatin

Stefan Aebi, Buran Kurdi-Haidar, Robert Gordon, Bruno Cenni, Hua Zheng, Daniel Fink, Randolph D. Christen, C. Richard Boland, Minoru Koi, Richard Fishel, and Stephen B. Howell
Cancer Res 1996 56: 3087-3090. [Abstract] [PDF]  

Genetic Alterations in Untreated Metastases and Androgen-independent Prostate Cancer Detected by Comparative Genomic Hybridization and Allelotyping

Michael L. Cher, G. Steven Bova, Dan H. Moore, Eric J. Small, Peter R. Carroll, Sokhom S. Pin, Jonathan I. Epstein, William B. Isaacs, and Ronald H. Jensen
Cancer Res 1996 56: 3091-3102. [Abstract] [PDF]  

Tumor Biology:

Involvement of Integrin _vß₃ in Cell Adhesion, Motility, and Liver Metastasis of Murine RAW117 Large Cell Lymphoma

Zhong Yun, David G. Menter, and Garth L. Nicolson
Cancer Res 1996 56: 3103-3111. [Abstract] [PDF]  

Identification of Differentially Expressed Messenger RNAs in Human Melanocytes and Melanoma Cells

Hans-Georg Simon, Barbara Risse, Monika Jost, Simone Oppenheimer, Csaba Kari, and Ulrich Rodeck
Cancer Res 1996 56: 3112-3117. [Abstract] [PDF]  

Expression of and Response to Interleukin 6 (IL6) in Human Mammary Tumors

Fulvio Basolo, Lisa Fiore, Gabriella Fontanini, Pier Giulio Conaldi, Simonetta Calvo, Valeria Falcone, and Antonio Toniolo
Cancer Res 1996 56: 3118-3122. [Abstract] [PDF]  

Plasminogen Activator Inhibitor 1 Messenger RNA Expression and Molecular Evidence for del(7)(q22) in Uterine Leiomyomas

Antigone Sourla, Constantin Polychronakos, Wendy Rong Zeng, Alain Nepveu, Asterios Kukuvitis, Françoise Naud, and Michael Koutsilieris
Cancer Res 1996 56: 3123-3128. [Abstract] [PDF]  

Mutant p53-induced Immortalization of Primary Human Mammary Epithelial Cells

Qingshen Gao, Stephen H. Hauser, Xiao-Long Liu, David E. Wazer, Hywell Madoc-Jones, and Vimla Band
Cancer Res 1996 56: 3129-3133. [Abstract] [PDF]  

Hyaluronate-independent Metastatic Behavior of CD44 Variant-expressing Pancreatic Carcinoma Cells

Jonathan P. Sleeman, Sigrid Arming, Jürgen F. Moll, Armin Hekele, Wolfgang Rudy, Larry S. Sherman, Günther Kreil, Helmut Ponta, and Peter Herrlich
Cancer Res 1996 56: 3134-3141. [Abstract] [PDF]  

Integrin VLA-2 (₂ß₁) Function in Postextravasation Movement of Human Rhabdomyosarcoma RD Cells in the Liver

Dolores Hangan, Shashi Uniyal, Vincent L. Morris, Ian C. MacDonald, Christoph von Ballestrem, Thu Chau, Eric E. Schmidt, Ann F. Chambers, Alan C. Groom, and Bosco M. C. Chan
Cancer Res 1996 56: 3142-3149. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1996 56: 3150-3152. [PDF]  

Employment Register of the American Association for Cancer Research

Cancer Res 1996 56: 3153-3162. [PDF]  

Erratum:

Assay of Enzyme Activity

Cancer Res 1996 56: 3152. [PDF]  

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