Advances in Brief:

Grb10: A New Substrate of the Insulin-like Growth Factor I Receptor

Andrea Morrione, Barbara Valentinis, Shiwei Li, James Y. T. Ooi, Ben Margolis, and Renato Baserga
Cancer Res 1996 56: 3165-3167. [Abstract] [PDF]  

BRCA1 Is a 220-kDa Nuclear Phosphoprotein That Is Expressed and Phosphorylated in a Cell Cycle-dependent Manner

Yumay Chen, Andrew A. Farmer, Chi-Fen Chen, Diane C. Jones, Phang-Lang Chen, and Wen-Hwa Lee
Cancer Res 1996 56: 3168-3172. [Abstract] [PDF]  

The FHIT Gene at 3p14.2 Is Abnormal in Breast Carcinomas

Massimo Negrini, Carmen Monaco, Igor Vorechovsky, Masataka Ohta, Teresa Druck, Raffaele Baffa, Kay Huebner, and Carlo M. Croce
Cancer Res 1996 56: 3173-3179. [Abstract] [PDF]  

Overexpression of int-5/aromatase in Mammary Glands of Transgenic Mice Results in the Induction of Hyperplasia and Nuclear Abnormalities

Rajeshwar Rao Tekmal, Nagalakshmi Ramachandra, Siddeswar Gubba, Vijayender R. Durgam, Jessica Mantione, Katsumi Toda, Yutaka Shizuta, and Dirck L. Dillehay
Cancer Res 1996 56: 3180-3185. [Abstract] [PDF]  

Reversion of Monochromosome-mediated Suppression of Tumorigenicity in Malignant Melanoma by Retroviral Transduction

Yan A. Su, Mike E. Ray, Ti Lin, Nancy E. Seidel, David M. Bodine, Paul S. Meltzer, and Jeffrey M. Trent
Cancer Res 1996 56: 3186-3191. [Abstract] [PDF]  

Manganese Superoxide Dismutase Expression in Human Central Nervous System Tumors

Charles S. Cobbs, Daniel S. Levi, Kenneth Aldape, and Mark A. Israel
Cancer Res 1996 56: 3192-3195. [Abstract] [PDF]  

Prognostic Significance of Circulating Matrix Metalloproteinase-2 to Tissue Inhibitor of Metalloproteinases-2 Ratio in Recurrence of Urothelial Cancer after Complete Resection

Kazuo Gohji, Noboru Fujimoto, Akio Fujii, Toyozo Komiyama, Jiro Okawa, and Motowo Nakajima
Cancer Res 1996 56: 3196-3198. [Abstract] [PDF]  

Reversible, p16-mediated Cell Cycle Arrest as Protection from Chemotherapy

Steven Stone, Priya Dayananth, and Alexander Kamb
Cancer Res 1996 56: 3199-3202. [Abstract] [PDF]  

Fluoropyrimidine-mediated Radiosensitization Depends on Cyclin E-dependent Kinase Activation

Theodore S. Lawrence, Mary A. Davis, and Tania L. Loney
Cancer Res 1996 56: 3203-3206. [Abstract] [PDF]  

Alternate Splicing of the rTS Gene Product and Its Overexpression in a 5-Fluorouracil-resistant Cell Line

Bruce J. Dolnick and Adrian R. Black
Cancer Res 1996 56: 3207-3210. [Abstract] [PDF]  

Tumor Necrosis Factor -induced Vascular Leakage Involves PECAM1 Phosphorylation

Elisabetta Ferrero, Antonello Villa, Maria Elena Ferrero, Elisabetta Toninelli, Jeffrey R. Bender, Ruggero Pardi, and Maria Raffaella Zocchi
Cancer Res 1996 56: 3211-3215. [Abstract] [PDF]  

Truncation at Conserved Terminal Regions of BRCA1 Protein Is Associated with Highly Proliferating Hereditary Breast Cancers

Hagay Sobol, Dominique Stoppa-Lyonnet, Brigitte Bressac-de-Paillerets, Jean-Philippe Peyrat, Fabienne Kerangueven, Nicolas Janin, Tetsuro Noguchi, François Eisinger, Jean-Marc Guinebretiere, Jocelyne Jacquemier, and Daniel Birnbaum
Cancer Res 1996 56: 3216-3219. [Abstract] [PDF]  

Gains, Losses, and Amplification of Genomic Material in Rhabdomyosarcoma Analyzed by Comparative Genomic Hybridization

Stephen Weber-Hall, John Anderson, Aidan McManus, Syuiti Abe, Takayuki Nojima, Ross Pinkerton, Kathy Pritchard-Jones, and Janet Shipley
Cancer Res 1996 56: 3220-3224. [Abstract] [PDF]  

Loss of Heterozygosity on the Long Arm of Chromosome 11 in Nasopharyngeal Carcinoma

Angela B. Y. Hui, Kwok-Wai Lo, Sing-Fai Leung, Peter H. K. Choi, Yin Fong, Joseph C. K. Lee, and Dolly P. Huang
Cancer Res 1996 56: 3225-3229. [Abstract] [PDF]  

DNA Copy Number Losses in Chromosome 14: An Early Change in Gastrointestinal Stromal Tumors

Wa'el El-Rifai, Maarit Sarlomo-Rikala, Markku Miettinen, Sakari Knuutila, and Leif C. Andersson
Cancer Res 1996 56: 3230-3233. [Abstract] [PDF]  

Complex Cadherin Expression in Renal Cell Carcinoma

Toru Shimazui, Laurence A. Giroldi, Pierre Paul Bringuier, Egbert Oosterwijk, and Jack A. Schalken
Cancer Res 1996 56: 3234-3237. [Abstract] [PDF]  

Carcinogenesis:

Inducible Nitric Oxide Synthase, Nitrotyrosine, and Apoptosis in Helicobacter pylori Gastritis: Effect of Antibiotics and Antioxidants

Elizabeth E. Mannick, Luis E. Bravo, Guillermo Zarama, J. Luis Realpe, Xiao-Jing Zhang, Bernardo Ruiz, Elizabeth T. H. Fontham, Robertino Mera, Mark J. S. Miller, and Pelayo Correa
Cancer Res 1996 56: 3238-3243. [Abstract] [PDF]  

Targeted Expression of Human O⁶-Methylguanine-DNA Methyltransferase (MGMT) in Transgenic Mice Protects against Tumor Initiation in Two-Stage Skin Carcinogenesis

Klaus Becker, Jörg Dosch, Cornelia M. Gregel, Brian A. Martin, and Bernd Kaina
Cancer Res 1996 56: 3244-3249. [Abstract] [PDF]  

GADD153/CHOP, a DNA Damage-inducible Protein, Reduced CAAT/Enhancer Binding Protein Activities and Increased Apoptosis in 32D cl3 Myeloid Cells

Alan D. Friedman
Cancer Res 1996 56: 3250-3256. [Abstract] [PDF]  

Growth Regulation by Peroxisome Proliferators: Opposing Activities in Early and Late G₁

Brian J. Ledwith, Timothy E. Johnson, Linda K. Wagner, Cindy J. Pauley, Sujata Manam, Sheila M. Galloway, and Warren W. Nichols
Cancer Res 1996 56: 3257-3264. [Abstract] [PDF]  

Regulation of Ornithine Decarboxylase in a Transformed Cell Line That Overexpresses Translation Initiation Factor eIF-4E

Lisa M. Shantz, Rei-Huang Hu, and Anthony E. Pegg
Cancer Res 1996 56: 3265-3269. [Abstract] [PDF]  

Calcium in Milk Products Precipitates Intestinal Fatty Acids and Secondary Bile Acids and Thus Inhibits Colonic Cytotoxicity in Humans

Mirjam J. A. P. Govers, Denise S. M. L. Termont, John A. Lapré, Jan H. Kleibeuker, Roel J. Vonk, and Roelof Van der Meer
Cancer Res 1996 56: 3270-3275. [Abstract] [PDF]  

Endocrinology:

Glucocorticoid Receptor Structure and Function in Glucocorticoid-resistant Small Cell Lung Carcinoma Cells

David W. Ray, Julian R. E. Davis, Anne White, and Adrian J. L. Clark
Cancer Res 1996 56: 3276-3280. [Abstract] [PDF]  

Experimental Therapeutics:

Potentiation of Photodynamic Therapy-elicited Antitumor Response by Localized Treatment with Granulocyte-Macrophage Colony-stimulating Factor

Gorazd Krosl, Mladen Korbelik, Jana Krosl, and Graeme J. Dougherty
Cancer Res 1996 56: 3281-3286. [Abstract] [PDF]  

ZD2767, an Improved System for Antibody-directed Enzyme Prodrug Therapy That Results in Tumor Regressions in Colorectal Tumor Xenografts

David C. Blakey, Philip J. Burke, David H. Davies, Robert I. Dowell, Simon J. East, Kay P. Eckersley, John E. Fitton, John McDaid, Roger G. Melton, Ion A. Niculescu-Duvaz, Philip E. Pinder, Surinder K. Sharma, Andrew F. Wright, and Caroline J. Springer
Cancer Res 1996 56: 3287-3292. [Abstract] [PDF]  

Ablation of Colorectal Xenografts with Combined Radioimmunotherapy and Tumor Blood Flow-modifying Agents

R. Barbara Pedley, Joan A. Boden, Robert Boden, Geoffrey M. Boxer, Aiden A. Flynn, Patricia A. Keep, and Richard H. J. Begent
Cancer Res 1996 56: 3293-3300. [Abstract] [PDF]  

In Vitro Uptake, Anabolism, and Cellular Retention of 1843U89 and Other Benzoquinazoline Inhibitors of Thymidylate Synthase

Mary H. Hanlon and Robert Ferone
Cancer Res 1996 56: 3301-3306. [Abstract] [PDF]  

Location of a Protease-hypersensitive Region in the Multidrug Resistance Protein (MRP) by Mapping of the Epitope of MRP-specific Monoclonal Antibody QCRL-1

David R. Hipfner, Kurt C. Almquist, Brenda D. Stride, Roger G. Deeley, and Susan P. C. Cole
Cancer Res 1996 56: 3307-3314. [Abstract] [PDF]  

Immunology:

Augmenting the Immunogenicity of Synthetic MUC1 Peptide Vaccines in Mice

Shengle Zhang, Linda A. Graeber, Friedhelm Helling, Govindaswami Ragupathi, Sucharita Adluri, Kenneth O. Lloyd, and Philip O. Livingston
Cancer Res 1996 56: 3315-3319. [Abstract] [PDF]  

Molecular Biology and Genetics:

Somatic Mutations of the APC Gene in Sporadic Hepatoblastomas

Hideaki Oda, Yasuo Imai, Yoko Nakatsuru, Jun-ichi Hata, and Takatoshi Ishikawa
Cancer Res 1996 56: 3320-3323. [Abstract] [PDF]  

Definition of a DNA Repair Domain in the Genomic Region Containing the Human p53 Gene

Dawn M. Tolbert and George J. Kantor
Cancer Res 1996 56: 3324-3330. [Abstract] [PDF]  

Semiautomated Assessment of Loss of Heterozygosity and Replication Error in Tumors

Federico Canzian, Reijo Salovaara, Akseli Hemminki, Paula Kristo, Robert B. Chadwick, Lauri A. Aaltonen, and Albert de la Chapelle
Cancer Res 1996 56: 3331-3337. [Abstract] [PDF]  

Allelotype Analysis of 2',3'-Dideoxycytidine- and 1,3-Butadiene-induced Lymphomas in B6C3F1 Mice

Shi-Mei Zhuang, Lena K. Eklund, Charles Cochran, Ghanta N. Rao, Roger W. Wiseman, and Peter Söderkvist
Cancer Res 1996 56: 3338-3343. [Abstract] [PDF]  

Tumor Biology:

The Relationship between Partial Pressure of Oxygen and Perfusion in Two Murine Tumors after X-Ray Irradiation: A Combined Gadopentetate Dimeglumine Dynamic Magnetic Resonance Imaging and in Vivo Electron Paramagnetic Resonance Oximetry Study

Fuminori Goda, Goran Bacic, Julia A. O'Hara, Bernard Gallez, Harold M. Swartz, and Jeffrey F. Dunn
Cancer Res 1996 56: 3344-3349. [Abstract] [PDF]  

Involvement of Heregulin-ß2 in the Acquisition of the Hormone-independent Phenotype of Breast Cancer Cells

Careen K. Tang, Cynthia Perez, Thomas Grunt, Caroline Waibel, Cheryl Cho, and Ruth Lupu
Cancer Res 1996 56: 3350-3358. [Abstract] [PDF]  

Transforming Growth Factor ß1 Stimulates Contrasting Responses in Metastatic versus Primary Mouse Prostate Cancer-derived Cell Lines in Vitro

Inder Sehgal, Patricia A. Baley, and Timothy C. Thompson
Cancer Res 1996 56: 3359-3365. [Abstract] [PDF]  

Involvement of Transforming Growth Factor ß1 in Autocrine Enhancement of Gelatinase B Secretion by Murine Metastatic Colon Carcinoma Cells

Satoru Shimizu, Yohko Nishikawa, Kazuhiko Kuroda, Shoko Takagi, Ken-ichi Kozaki, Sumiko Hyuga, Shinsuke Saga, and Mutsushi Matsuyama
Cancer Res 1996 56: 3366-3370. [Abstract] [PDF]  

Identification of a Novel Serine Protease-like Gene, the Expression of Which Is Down-Regulated during Breast Cancer Progression

Xiao-Long Liu, David E. Wazer, Kiyoko Watanabe, and Vimla Band
Cancer Res 1996 56: 3371-3379. [Abstract] [PDF]  

Special Article:

NIEHS/AACR Task Force on the Advancement of Minorities in Science: Vision for a Model Program

Marian Johnson-Thompson, Colleen Sullivan, and Kenneth Olden
Cancer Res 1996 56: 3380-3386. [PDF]  

Articles:

Announcements

Cancer Res 1996 56: 3387-3389. [PDF]  

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