Advances in Brief:

Identification by Differential Display of Annexin-VI, a Gene Differentially Expressed during Melanoma Progression

Giulio Francia, Stephen D. Mitchell, Stephen E. Moss, Andrew M. Hanby, John F. Marshall, and Ian R. Hart
Cancer Res 1996 56: 3855-3858. [Abstract] [PDF]  

Tyrphostin AG 1478 Preferentially Inhibits Human Glioma Cells Expressing Truncated Rather than Wild-Type Epidermal Growth Factor Receptors

Yuchun Han, Cornelio Gacusana Caday, Anil Nanda, Webster K. Cavenee, and H-J. Su Huang
Cancer Res 1996 56: 3859-3861. [Abstract] [PDF]  

Gain-of-Function p53 Mutations Enhance Alteration of the T-Cell Receptor following X-Irradiation, Independently of the Cell Cycle and Cell Survival

Keisuke S. Iwamoto, Terumi Mizuno, Takashi Ito, Naohiro Tsuyama, Seishi Kyoizumi, and Toshio Seyama
Cancer Res 1996 56: 3862-3865. [Abstract] [PDF]  

¹²-Prostaglandin-J₂ Is Cytotoxic in Human Malignancies and Synergizes with Both Cisplatin and Radiation

Edward F. McClay, Paul J. Winski, Jeffery A. Jones, Joseph Jennerette, III, and Sebastiano Gattoni-Celli
Cancer Res 1996 56: 3866-3869. [Abstract] [PDF]  

Elevated Soluble Fas (sFas) Levels in Nonhematopoietic Human Malignancy

Gregory P. Midis, Yu Shen, and Laurie B. Owen-Schaub
Cancer Res 1996 56: 3870-3874. [Abstract] [PDF]  

Inactivation of the CDKN2 Gene by Homozygous Deletion and de Novo Methylation Is Associated with Advanced Stage Esophageal Squamous Cell Carcinoma

Chihaya Maesawa, Gen Tamura, Satoshi Nishizuka, Satoshi Ogasawara, Kaoru Ishida, Masanori Terashima, Ken Sakata, Nobuhiro Sato, Kazuyoshi Saito, and Ryoichi Satodate
Cancer Res 1996 56: 3875-3878. [Abstract] [PDF]  

bfl-1, a bcl-2 Homologue, Suppresses p53-induced Apoptosis and Exhibits Potent Cooperative Transforming Activity

Cleta D'Sa-Eipper, T. Subramanian, and G. Chinnadurai
Cancer Res 1996 56: 3879-3882. [Abstract] [PDF]  

Type of Estrogen Receptor Determines Response to Antiestrogen Therapy

Erica Villa, Aisha Dugani, Emanuela Fantoni, Lorenzo Camellini, Paola Buttafoco, Antonella Grottola, Guglielmo Pompei, Mario De Santis, Alberto Ferrari, and Federico Manenti
Cancer Res 1996 56: 3883-3885. [Abstract] [PDF]  

Two Distinct Amplified Regions at 17q11–q21 Involved in Human Primary Breast Cancer

Ivan Bièche, Catherine Tomasetto, Catherine H. Régnier, Christel Moog-Lutz, Marie-Christine Rio, and Rosette Lidereau
Cancer Res 1996 56: 3886-3890. [Abstract] [PDF]  

Regulation of Vascular Endothelial Growth Factor Expression in Human Colon Carcinoma Cells by Cell Density

Aaryan N. Koura, Wenbiao Liu, Yasuhiko Kitadai, Rakesh K. Singh, Robert Radinsky, and Lee M. Ellis
Cancer Res 1996 56: 3891-3894. [Abstract] [PDF]  

Rapamycin Inhibits Constitutive p70^s6k Phosphorylation, Cell Proliferation, and Colony Formation in Small Cell Lung Cancer Cells

Thomas Seufferlein and Enrique Rozengurt
Cancer Res 1996 56: 3895-3897. [Abstract] [PDF]  

Antisense Epidermal Growth Factor Receptor Transfection Impairs the Proliferative Ability of Human Rhabdomyosarcoma Cells

Carla De Giovanni, Lorena Landuzzi, Flavia Frabetti, Giordano Nicoletti, Cristiana Griffoni, Ilaria Rossi, Maria Mazzotti, Luigi Scotto, Patrizia Nanni, and Pier-Luigi Lollini
Cancer Res 1996 56: 3898-3901. [Abstract] [PDF]  

Biochemistry and Biophysics:

2B1 Antigen Characteristically Expressed on Extracellular Matrices of Human Malignant Tumors Is a Large Chondroitin Sulfate Proteoglycan, PG-M/Versican

Zenzo Isogai, Tamayuki Shinomura, Naomi Yamakawa, Jun Takeuchi, Takuo Tsuji, Dick Heinegård, and Koji Kimata
Cancer Res 1996 56: 3902-3908. [Abstract] [PDF]  

Protease Inhibitors Induce Specific Changes in Protein Tyrosine Phosphorylation That Correlate with Inhibition of Apoptosis in Myeloid Cells

Nadya L. Lumelsky and Bradford S. Schwartz
Cancer Res 1996 56: 3909-3914. [Abstract] [PDF]  

Carcinogenesis:

Combined Analysis of Inherited Polymorphisms in Arylamine N-Acetyltransferase 2, Glutathione S-Transferases M1 and T1, Microsomal Epoxide Hydrolase, and Cytochrome P450 Enzymes as Modulators of Bladder Cancer Risk

Jürgen Brockmöller, Ingolf Cascorbi, Reinhold Kerb, and Ivar Roots
Cancer Res 1996 56: 3915-3925. [Abstract] [PDF]  

Characterization of Purified Human Recombinant Cytochrome P4501A1-Ile⁴⁶² and -Val⁴⁶²: Assessment of a Role for the Rare Allele in Carcinogenesis

Zhi-Yi Zhang, Michael J. Fasco, Lili Huang, F. Peter Guengerich, and Laurence S. Kaminsky
Cancer Res 1996 56: 3926-3933. [Abstract] [PDF]  

TuAg.1 Is the Liver Isoform of the Rat Colon Tumor-associated Antigen pE4 and a Member of the Immunoglobulin-like Supergene Family

Yow-Pin Lim, Lizeth C. Fowler, Douglas C. Hixson, Tarek Wehbe, and Nancy L. Thompson
Cancer Res 1996 56: 3934-3940. [Abstract] [PDF]  

Human N-Acetylation of Benzidine: Role of NAT1 and NAT2

Terry V. Zenser, Vijaya M. Lakshmi, Timothy D. Rustan, Mark A. Doll, Anne C. Deitz, Bernard B. Davis, and David W. Hein
Cancer Res 1996 56: 3941-3947. [Abstract] [PDF]  

Clinical Investigations:

Effects of Hyperthermic Isolated Limb Perfusion with Recombinant Tumor Necrosis Factor and Melphalan on the Human Fibrinolytic System

Jan H. Zwaveling, John K. Maring, André B. Mulder, Victor J. J. Bom, Robert J. van Ginkel, Heimen Schraffordt Koops, Armand R. J. Girbes, Harald J. Hoekstra, and Jan van der Meer
Cancer Res 1996 56: 3948-3953. [Abstract] [PDF]  

Endocrinology:

Uterine Expression of Vascular Endothelial Growth Factor Is Increased by Estradiol and Tamoxifen

Salman M. Hyder, George M. Stancel, Constance Chiappetta, Lata Murthy, Holly L. Boettger-Tong, and Sari Makela
Cancer Res 1996 56: 3954-3960. [Abstract] [PDF]  

Epidemiology:

Homozygous Rapid Arylamine N-Acetyltransferase (NAT2) Genotype as a Susceptibility Factor for Lung Cancer

Ingolf Cascorbi, Jürgen Brockmöller, Przemyslaw M. Mrozikiewiz, Steffen Bauer, Robert Loddenkemper, and Ivar Roots
Cancer Res 1996 56: 3961-3966. [Abstract] [PDF]  

Interleukin 2 Production in Vitro by Peripheral Lymphocytes in Response to Human Papillomavirus-derived Peptides: Correlation with Cervical Pathology

Taku Tsukui, Allan Hildesheim, Mark H. Schiffman, Joseph Lucci, III, David Contois, Patricia Lawler, Brenda B. Rush, Attila T. Lorincz, Alice Corrigan, Robert D. Burk, Weimin Qu, Margaret A. Marshall, Dean Mann, Mary Carrington, Mario Clerici, Gene M. Shearer, David P. Carbone, David R. Scott, Richard A. Houghten, and Jay A. Berzofsky
Cancer Res 1996 56: 3967-3974. [Abstract] [PDF]  

Benzo(a)pyrene Diol Epoxide-induced Chromosomal Aberrations and Risk of Lung Cancer

Qingyi Wei, Jun Gu, Lie Cheng, Melissa L. Bondy, Hong Jiang, Waun Ki Hong, and Margaret R. Spitz
Cancer Res 1996 56: 3975-3979. [Abstract] [PDF]  

Experimental Therapeutics:

Combination Chemotherapy and Photodynamic Therapy with N-(2-Hydroxypropyl)methacrylamide Copolymer-bound Anticancer Drugs Inhibit Human Ovarian Carcinoma Heterotransplanted in Nude Mice

C. Matthew Peterson, Jing Ming Lu, Yongren Sun, C. Anthony Peterson, Jane-Guo Shiah, Richard C. Straight, and Jindrich Kopecek
Cancer Res 1996 56: 3980-3985. [Abstract] [PDF]  

Intrathecal Chemotherapy with 1,3-Bis(2-chloroethyl)-1-nitrosourea Encapsulated into Hybrid Liposomes for Meningeal Gliomatosis: An Experimental Study

Isao Kitamura, Masato Kochi, Yoko Matsumoto, Ryuichi Ueoka, Jun-ichi Kuratsu, and Yukitaka Ushio
Cancer Res 1996 56: 3986-3992. [Abstract] [PDF]  

Determinants of Tamoxifen Sensitivity Control the Nature of the Synergistic Interaction between Tamoxifen and Cisplatin

Edward F. McClay, Jeffrey A. Jones, Paul J. Winski, Kathleen D. Albright, Randolph D. Christen, and Stephen B. Howell
Cancer Res 1996 56: 3993-3997. [Abstract] [PDF]  

Intravenous RMP-7 Selectively Increases Uptake of Carboplatin into Rat Brain Tumors

P. J. Elliott, N. J. Hayward, R. L. Dean, D. G. Blunt, and R. T. Bartus
Cancer Res 1996 56: 3998-4005. [Abstract] [PDF]  

Dual Modes of Death Induced by Etoposide in Human Epithelial Tumor Cells Allow Bcl-2 to Inhibit Apoptosis without Affecting Clonogenic Survival

Richard B. Lock and Lolita Stribinskiene
Cancer Res 1996 56: 4006-4012. [Abstract] [PDF]  

Molecular Biology and Genetics:

A Soluble Insulin-like Growth Factor I Receptor That Induces Apoptosis of Tumor Cells in Vivo and Inhibits Tumorigenesis

Consuelo D'Ambrosio, Andres Ferber, Mariana Resnicoff, and Renato Baserga
Cancer Res 1996 56: 4013-4020. [Abstract] [PDF]  

Microsatellite Instability Correlates with Reduced Survival and Poor Disease Prognosis in Breast Cancer

Thomas G. Paulson, Fred A. Wright, Barbara A. Parker, Valentina Russack, and Geoffrey M. Wahl
Cancer Res 1996 56: 4021-4026. [Abstract] [PDF]  

Tumor Biology:

Increased Brain Tumor Microvessel Permeability after Intracarotid Bradykinin Infusion Is Mediated by Nitric Oxide

Shin Nakano, Koichiro Matsukado, and Keith L. Black
Cancer Res 1996 56: 4027-4031. [Abstract] [PDF]  

Complete Inhibition of Angiogenesis and Growth of Microtumors by Anti-Vascular Endothelial Growth Factor Neutralizing Antibody: Novel Concepts of Angiostatic Therapy from Intravital Videomicroscopy

Per Borgström, Kenneth J. Hillan, Pragada Sriramarao, and Napolenone Ferrara
Cancer Res 1996 56: 4032-4039. [Abstract] [PDF]  

An Experimental Model of Bone Metastasis by Human Lung Cancer Cells: The Role of Parathyroid Hormone-related Protein in Bone Metastasis

Haruo Iguchi, Shohei Tanaka, Yukiko Ozawa, Tomiko Kashiwakuma, Tatsuji Kimura, Toru Hiraga, Hidehiro Ozawa, and Akira Kono
Cancer Res 1996 56: 4040-4043. [Abstract] [PDF]  

Inhibition of Hamster Mesothelioma Tumorigenesis by an Antisense Expression Plasmid to the Insulin-like Growth Factor-1 Receptor

Harvey I. Pass, Daphne J. Y. Mew, Michele Carbone, Wilbert A. Matthews, Jessica S. Donington, Renato Baserga, Cheryl L. Walker, Mariana Resnicoff, and Seth M. Steinberg
Cancer Res 1996 56: 4044-4048. [Abstract] [PDF]  

Presence of an Insulin-like Growth Factor I Autocrine Loop Predicts Uterine Fibroid Responsiveness to Tamoxifen

Susan R. Howe, Harvey I. Pass, Stephen P. Ethier, Wilbert J. Matthews, and Cheryl Walker
Cancer Res 1996 56: 4049-4055. [Abstract] [PDF]  

Parathyroid Hormone-related Protein Gene Expression in Human Squamous Carcinoma Cells Is Repressed by Mutant Isoforms of p53

John Foley, John J. Wysolmerski, Arthur E. Broadus, and William M. Philbrick
Cancer Res 1996 56: 4056-4062. [Abstract] [PDF]  

E-Cadherin Expression in Human Breast Cancer Cells Suppresses the Development of Osteolytic Bone Metastases in an Experimental Metastasis Model

Gabriel Mbalaviele, Colin R. Dunstan, Akira Sasaki, Paul J. Williams, Gregory R. Mundy, and Toshiyuki Yoneda
Cancer Res 1996 56: 4063-4070. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1996 56: 4071-4074. [PDF]  

Announcements:

Correction

Yumay Chen, Andrew Farmer, Chi-Fen Chen, Diane Jones, Phang-Lang Chen, and Wen-Hwe Lee
Cancer Res 1996 56: 4074 [PDF]  

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