Advances in Brief:

Noninvasive Imaging of Herpes Virus Thymidine Kinase Gene Transfer and Expression: A Potential Method for Monitoring Clinical Gene Therapy

Juri G. Tjuvajev, Ronald Finn, Kyoichi Watanabe, Revathi Joshi, Takamitsu Oku, John Kennedy, Bradley Beattie, Jason Koutcher, Steven Larson, and Ronald G. Blasberg
Cancer Res 1996 56: 4087-4095. [Abstract] [PDF]  

Metastatic Prostate Cancer in a Transgenic Mouse

Jeffrey R. Gingrich, Roberto J. Barrios, Ronald A. Morton, Brendan F. Boyce, Francesco J. DeMayo, Milton J. Finegold, Roxani Angelopoulou, Jeffrey M. Rosen, and Norman M. Greenberg
Cancer Res 1996 56: 4096-4102. [Abstract] [PDF]  

Reduced DNA Repair Capacity in Lung Cancer Patients

Qingyi Wei, Lie Cheng, Waun Ki Hong, and Margaret R. Spitz
Cancer Res 1996 56: 4103-4107. [Abstract] [PDF]  

Association of Prostate Cancer with Vitamin D Receptor Gene Polymorphism

Jack A. Taylor, Ari Hirvonen, Mary Watson, Gary Pittman, James L. Mohler, and Douglas A. Bell
Cancer Res 1996 56: 4108-4110. [Abstract] [PDF]  

Gastrin Gene Expression Is Required for the Proliferation and Tumorigenicity of Human Colon Cancer Cells

Pomila Singh, Azar Owlia, Andrea Varro, Bosong Dai, S. Rajaraman, and T. Wood
Cancer Res 1996 56: 4111-4115. [Abstract] [PDF]  

Apoptosis Induced by X-Irradiation of rec-myc Cells Is Postmitotic and not Predicted by the Time after Irradiation or Behavior of Sister Cells

Charles A. Vidair, Chang H. Chen, Clifton C. Ling, and William C. Dewey
Cancer Res 1996 56: 4116-4118. [Abstract] [PDF]  

p16 and p16ß Are Potent Growth Suppressors of Head and Neck Squamous Carcinoma Cells in Vitro

William H. Liggett, Jr., Duane A. Sewell, James Rocco, Steven A. Ahrendt, Wayne Koch, and David Sidransky
Cancer Res 1996 56: 4119-4123. [Abstract] [PDF]  

A Human Canalicular Multispecific Organic Anion Transporter (cMOAT) Gene Is Overexpressed in Cisplatin-resistant Human Cancer Cell Lines with Decreased Drug Accumulation

Ken Taniguchi, Morimasa Wada, Kimitoshi Kohno, Takanori Nakamura, Takeshi Kawabe, Mina Kawakami, Kazuhiro Kagotani, Katsuzumi Okumura, Shin-ichi Akiyama, and Michihiko Kuwano
Cancer Res 1996 56: 4124-4129. [Abstract] [PDF]  

ATM Mutations in Cancer Families

Igor Vorechovsky, Liping Luo, Annika Lindblom, Massimo Negrini, A. David B. Webster, Carlo M. Croce, and Lennart Hammarström
Cancer Res 1996 56: 4130-4133. [Abstract] [PDF]  

Prognosis Is Correlated with p53 Mutation Type for Soft Tissue Sarcoma Patients

Helge Taubert, Axel Meye, and Peter Würl
Cancer Res 1996 56: 4134-4136. [Abstract] [PDF]  

Overexpression of Protein Kinase C-zeta (PKC-) Inhibits Invasive and Metastatic Abilities of Dunning R-3327 MAT-LyLu Rat Prostate Cancer Cells

C. Thomas Powell, Jürgen E. Gschwend, William R. Fair, Nicole J. Brittis, Diane Stec, and Robert Huryk
Cancer Res 1996 56: 4137-4141. [Abstract] [PDF]  

Active Site-directed Double Mutants of Dihydrofolate Reductase

Emine A. Ercikan-Abali, Shin Mineishi, Youzhi Tong, Saori Nakahara, Mark C. Waltham, Debabrata Banerjee, Wen Chen, Michel Sadelain, and Joseph R. Bertino
Cancer Res 1996 56: 4142-4145. [Abstract] [PDF]  

Integrin Activation Suppresses Etoposide-induced DNA Strand Breakage in Cultured Murine Tumor-derived Endothelial Cells

Dale G. Hoyt, James M. Rusnak, Robert J. Mannix, Ruth A. Modzelewski, Candace S. Johnson, and John S. Lazo
Cancer Res 1996 56: 4146-4149. [Abstract] [PDF]  

Identification and Characterization of Proximal 6q Deletions in Prostate Cancer

Kathleen A. Cooney, Jon C. Wetzel, Christina M. Consolino, and Kirk J. Wojno
Cancer Res 1996 56: 4150-4153. [Abstract] [PDF]  

Clinical Investigations:

Prognostic Value of Cadherin-associated Molecules (-, ß-, and -Catenins and p120^cas) in Bladder Tumors

Toru Shimazui, Jack A. Schalken, Laurence A. Giroldi, Cornelius F. J. Jansen, Hideyuki Akaza, Kenkichi Koiso, Frans M. J. Debruyne, and Pierre Paul Bringuier
Cancer Res 1996 56: 4154-4158. [Abstract] [PDF]  

Expression of Cell Cycle-regulated Proteins in Prostate Cancer

Robert D. Mashal, Susan Lester, Christopher Corless, Jerome P. Richie, Reena Chandra, Kathleen J. Propert, and Anindya Dutta
Cancer Res 1996 56: 4159-4163. [Abstract] [PDF]  

Experimental Therapeutics:

Hormone-induced Apoptosis by Fas-Nuclear Receptor Fusion Proteins: Novel Biological Tools for Controlling Apoptosis in Vivo

Hirohide Takebayashi, Hiroji Oida, Kazuko Fujisawa, Masahiro Yamaguchi, Takatoshi Hikida, Manabu Fukumoto, Shuh Narumiya, and Akira Kakizuka
Cancer Res 1996 56: 4164-4170. [Abstract] [PDF]  

Reversal of P-Glycoprotein-mediated Multidrug Resistance by a Potent Cyclopropyldibenzosuberane Modulator, LY335979

Anne H. Dantzig, Robert L. Shepard, Jin Cao, Kevin L. Law, William J. Ehlhardt, Todd M. Baughman, Thomas F. Bumol, and James J. Starling
Cancer Res 1996 56: 4171-4179. [Abstract] [PDF]  

Molecular Determinants in the Plasma Clearance and Tissue Distribution of Ribonucleases of the Ribonuclease A Superfamily

Veena M. Vasandani, You-Neng Wu, Stanislaw M. Mikulski, Richard J. Youle, and Cynthia Sung
Cancer Res 1996 56: 4180-4186. [Abstract] [PDF]  

Uptake and Metabolism of the New Anticancer Compound ß-L-(-)-Dioxolane-Cytidine in Human Prostate Carcinoma DU-145 Cells

Kristie L. Grove and Yung-Chi Cheng
Cancer Res 1996 56: 4187-4191. [Abstract] [PDF]  

Commitment to Erythroid Differentiation in Mouse Erythroleukemia Cells Is Controlled by Alterations in Topoisomerase II Phosphorylation

Andreas I. Constantinou, Andrew T. M. Vaughan, Hiroshi Yamasaki, and Narayana Kamath
Cancer Res 1996 56: 4192-4199. [Abstract] [PDF]  

Dose-Response Relationship of Dexrazoxane for Prevention of Doxorubicin-induced Cardiotoxicity in Mice, Rats, and Dogs

Anthony R. Imondi, Paola Della Torre, Guy Mazué, Timothy M. Sullivan, Thomas L. Robbins, Larry M. Hagerman, Arturo Podestà, and Giovanni Pinciroli
Cancer Res 1996 56: 4200-4204. [Abstract] [PDF]  

Immunology:

MUC1-specific Targeting Immunotherapy with Bispecific Antibodies: Inhibition of Xenografted Human Bile Duct Carcinoma Growth

Yu Katayose, Toshio Kudo, Masanori Suzuki, Masao Shinoda, Susumu Saijyo, Naoki Sakurai, Hisaaki Saeki, Kenji Fukuhara, Kohzo Imai, and Seiki Matsuno
Cancer Res 1996 56: 4205-4212. [Abstract] [PDF]  

Interleukin 6 Receptor Superantagonists Are Potent Inducers of Human Multiple Myeloma Cell Death

Anna Demartis, Francesca Bernassola, Rocco Savino, Gennaro Melino, and Gennaro Ciliberto
Cancer Res 1996 56: 4213-4218. [Abstract] [PDF]  

Molecular Biology and Genetics:

Genetic Aberrations in Adrenocortical Tumors Detected Using Comparative Genomic Hybridization Correlate with Tumor Size and Malignancy

Magnus Kjellman, Olli-P. Kallioniemi, Ritva Karhu, Anders Höög, Lars-Ove Farnebo, Gert Auer, Catharina Larsson, and Martin Bäckdahl
Cancer Res 1996 56: 4219-4223. [Abstract] [PDF]  

Role of the Human Y Box-binding Protein YB-1 in Cellular Sensitivity to the DNA-damaging Agents Cisplatin, Mitomycin C, and Ultraviolet Light

Takefumi Ohga, Koji Koike, Mayumi Ono, Yoshinari Makino, Yasuharu Itagaki, Morimasa Tanimoto, Michihiko Kuwano, and Kimitoshi Kohno
Cancer Res 1996 56: 4224-4228. [Abstract] [PDF]  

Differential and Antagonistic Effects of v-Jun and c-Jun

Meihua Gao, Iain Morgan, and Peter K. Vogt
Cancer Res 1996 56: 4229-4235. [Abstract] [PDF]  

Tumor Biology:

The Protein Tyrosine Phosphatase DEP-1 Is Induced during Differentiation and Inhibits Growth of Breast Cancer Cells

Maccon M. Keane, Geoffrey A. Lowrey, Seth A. Ettenberg, Mark A. Dayton, and Stan Lipkowitz
Cancer Res 1996 56: 4236-4243. [Abstract] [PDF]  

The Breast Mucin MUC1 as a Novel Adhesion Ligand for Endothelial Intercellular Adhesion Molecule 1 in Breast Cancer

Lyle H. Regimbald, Linda M. Pilarski, B. Michael Longenecker, Mark A. Reddish, Gabrielle Zimmermann, and Judith C. Hugh
Cancer Res 1996 56: 4244-4249. [Abstract] [PDF]  

Construction of Phosphorylatable Monoclonal Antibody to a Tumor-associated Antigen

Lei Lin, Bruce Daugherty, Jeffrey Schlom, and Sidney Pestka
Cancer Res 1996 56: 4250-4254. [Abstract] [PDF]  

Inhibition of Neuropeptide-stimulated Tyrosine Phosphorylation and Tyrosine Kinase Activity Stimulates Apoptosis in Small Cell Lung Cancer Cells

April Tallett, Edwin R. Chilvers, Sharon Hannah, Ian Dransfield, Mark F. Lawson, Christopher Haslett, and Tariq Sethi
Cancer Res 1996 56: 4255-4263. [Abstract] [PDF]  

Tumor Angiogenesis and Interstitial Hypertension

Yves Boucher, Michael Leunig, and Rakesh K. Jain
Cancer Res 1996 56: 4264-4266. [Abstract] [PDF]  

Letters to the Editor:

Correspondence re: E. Farber, Cell Proliferation as a Major Risk Factor for Cancer: A Concept of Doubtful Validity. Cancer Res., 55: 3759–3762, 1995: Letter

Grant N. Stemmermann, Amy Noffsinger, and Cecilia M. Fenoglio-Preiser
Cancer Res 1996 56: 4267 [PDF]  

Correspondence re: E. Farber, Cell Proliferation as a Major Risk Factor for Cancer: A Concept of Doubtful Validity. Cancer Res., 55: 3759–3762, 1995: Letter

Bruce N. Ames and Lois Swirsky Gold
Cancer Res 1996 56: 4267-4269. [PDF]  

Correspondence re: E. Farber, Cell Proliferation as a Major Risk Factor for Cancer: A Concept of Doubtful Validity. Cancer Res., 55: 3759–3762, 1995: Letter

Samuel M. Cohen and Leon B. Ellwein
Cancer Res 1996 56: 4269-4270. [PDF]  

Correspondence re: E. Farber, Cell Proliferation as a Major Risk Factor for Cancer: A Concept of Doubtful Validity. Cancer Res., 55: 3759–3762, 1995: Letter

Byron E. Butterworth
Cancer Res 1996 56: 4270-4272. [PDF]  

Correspondence re: E. Farber, Cell Proliferation as a Major Risk Factor for Cancer: A Concept of Doubtful Validity. Cancer Res., 55: 3759–3762, 1995: Reply

Emmanuel Farber
Cancer Res 1996 56: 4272-4274. [PDF]  

Correspondence re: S. J. London et al., Lung Cancer Risk in African-Americans in Relation to a Race-specific CYP1A1 Polymorphism. Cancer Res., 55: 6035–6037, 1995.

Emanuela Taioli and Seymour J. Garte
Cancer Res 1996 56: 4275 [PDF]  

Correspondence re: S. J. London et al., Lung Cancer Risk in African-Americans in Relation to a Race-specific CYP1A1 Polymorphism. Cancer Res., 55: 6035–6037, 1995. — Reply

Stephanie J. London, William C. Navidi, Ann K. Daly, and Jeffrey R. Idle
Cancer Res 1996 56: 4276-4277. [PDF]  

Meeting Reports:

Psychoneuroimmunology and Cancer: Fifteenth Sapporo Cancer Seminar

Hugo O. Besedovsky, Ronald B. Herberman, Lydia R. Temoshok, and Fujiro Sendo
Cancer Res 1996 56: 4278-4281. [PDF]  

Seventh Annual Pezcoller Symposium: Cancer Genes—Functional Aspects

Enrico Mihich and David Housman
Cancer Res 1996 56: 4282-4287. [PDF]  

The XVIII Symposium of the International Association for Comparative Research on Leukemia & Related Diseases (IACRLRD): Leukemia and Lymphoma/Pathogenesis and Treatment/Molecular Aspects

Kuan-Teh Jeang and Frank J. Rauscher, III
Cancer Res 1996 56: 4288-4292. [PDF]  

Articles:

Announcements

Cancer Res 1996 56: 4293-4295. [PDF]  

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