Advances in Brief:

A Mutation in the Transforming Growth Factor ß Type II Receptor Gene Promoter Associated with Loss of Gene Expression

Teresita Muñoz-Antonia, Xiaochuan Li, Michael Reiss, Rosalind Jackson, and Scott Antonia
Cancer Res 1996 56: 4831-4835. [Abstract] [PDF]  

Altered Expression of hMSH2 and hMLH1 in Tumors with Microsatellite Instability and Genetic Alterations in Mismatch Repair Genes

Stephen N. Thibodeau, Amy J. French, Patrick C. Roche, Julie M. Cunningham, David J. Tester, Noralane M. Lindor, Gabriela Moslein, Sean M. Baker, R. Michael Liskay, Lawrence J. Burgart, Ronald Honchel, and Kevin C. Halling
Cancer Res 1996 56: 4836-4840. [Abstract] [PDF]  

Widespread Loss of Gelsolin in Breast Cancers of Humans, Mice, and Rats

Harold L. Asch, Karen Head, Yan Dong, Farah Natoli, Janet S. Winston, James L. Connolly, and Bonnie B. Asch
Cancer Res 1996 56: 4841-4845. [Abstract] [PDF]  

Transformation of Epithelial Cells Stably Transfected with H₂O₂-generating Peroxisomal Urate Oxidase

Ruiyin Chu, Yulian Lin, Kirthi C. Reddy, Jie Pan, M. Sambasiva Rao, Janardan K. Reddy, and Anjana V. Yeldandi
Cancer Res 1996 56: 4846-4852. [Abstract] [PDF]  

Somatic Mutations of the RET Proto-oncogene Are Not Required for Tumor Development in Multiple Endocrine Neoplasia Type 2 (MEN 2) Gene Carriers

Rudy M. Landsvater, Mireille J. de Wit, Richard A. Zewald, Robert M. W. Hofstra, Charles H. C. M. Buys, Hans-Kristian Ploos van Amstel, Jo W. M. Höppener, and Cornelis J. M. Lips
Cancer Res 1996 56: 4853-4855. [Abstract] [PDF]  

Flavopiridol: A Cytotoxic Flavone That Induces Cell Death in Noncycling A549 Human Lung Carcinoma Cells

Keith C. Bible and Scott H. Kaufmann
Cancer Res 1996 56: 4856-4861. [Abstract] [PDF]  

A Methylenetetrahydrofolate Reductase Polymorphism and the Risk of Colorectal Cancer

Jia Chen, Edward Giovannucci, Karl Kelsey, Eric B. Rimm, Meir J. Stampfer, Graham A. Colditz, Donna Spiegelman, Walter C. Willett, and David J. Hunter
Cancer Res 1996 56: 4862-4864. [Abstract] [PDF]  

Silencing of the Mammary-derived Growth Inhibitor (MDGI) Gene in Breast Neoplasms Is Associated with Epigenetic Changes

Hung Huynh, Lesley Alpert, and Michael Pollak
Cancer Res 1996 56: 4865-4870. [Abstract] [PDF]  

The FHIT and PTPRG Genes Are Deleted in Benign Proliferative Breast Disease Associated with Familial Breast Cancer and Cytogenetic Rearrangements of Chromosome Band 3p14

Ioannis Panagopoulos, Nikos Pandis, Sofia Thelin, Catarina Petersson, Fredrik Mertens, Åke Borg, Ulf Kristoffersson, Felix Mitelman, and Pierre Åman
Cancer Res 1996 56: 4871-4875. [Abstract] [PDF]  

KAI1 Expression Is Up-Regulated in Early Pancreatic Cancer and Decreased in the Presence of Metastases

Xiaozhong Guo, Helmut Friess, Hans U. Graber, Mikiya Kashiwagi, Arthur Zimmermann, Murray Korc, and Markus W. Büchler
Cancer Res 1996 56: 4876-4880. [Abstract] [PDF]  

The Role of DNA Mismatch Repair in Platinum Drug Resistance

Daniel Fink, Sibylle Nebel, Stefan Aebi, Hua Zheng, Bruno Cenni, Alissar Nehmé, Randolph D. Christen, and Stephen B. Howell
Cancer Res 1996 56: 4881-4886. [Abstract] [PDF]  

Human Prostate Carcinoma Cells Express Enzymatic Activity That Converts Human Plasminogen to the Angiogenesis Inhibitor, Angiostatin

Stephen Gately, Przemyslaw Twardowski, M. Sharon Stack, Matthew Patrick, Lisa Boggio, Deborah L. Cundiff, H. William Schnaper, Laird Madison, Olga Volpert, Noel Bouck, Jan Enghild, Hau C. Kwaan, and Gerald A. Soff
Cancer Res 1996 56: 4887-4890. [Abstract] [PDF]  

Adenovirus-based Transfer of Wild-Type p53 Gene Increases Ovarian Tumor Radiosensitivity

David Gallardo, Ken E. Drazan, and William H. McBride
Cancer Res 1996 56: 4891-4893. [Abstract] [PDF]  

Carcinogenesis:

Progression of Prostatic Intraepithelial Neoplasia to Invasive Carcinoma in C3(1)/SV40 Large T Antigen Transgenic Mice: Histopathological and Molecular Biological Alterations

Masa-Aki Shibata, Jerrold M. Ward, Deborah E. Devor, Min-Ling Liu, and Jeffrey E. Green
Cancer Res 1996 56: 4894-4903. [Abstract] [PDF]  

Chemoprevention of 4-Nitroquinoline 1-Oxide-induced Rat Oral Carcinogenesis by the Dietary Flavonoids Chalcone, 2-Hydroxychalcone, and Quercetin

Hiroki Makita, Takuji Tanaka, Hideki Fujitsuka, Norichika Tatematsu, Kumiko Satoh, Akira Hara, and Hideki Mori
Cancer Res 1996 56: 4904-4909. [Abstract] [PDF]  

Apoptosis, Cell Replication, and Western-style Diet-induced Tumorigenesis in Mouse Colon

Mauro Risio, Martin Lipkin, Harold Newmark, Kan Yang, Francesco P. Rossini, Vernon E. Steele, Charles W. Boone, and Gary J. Kelloff
Cancer Res 1996 56: 4910-4916. [Abstract] [PDF]  

Circulating Anti-p53 Antibodies in Esophageal Cancer Patients Are Found Predominantly in Individuals with p53 Core Domain Mutations in Their Tumors

Marie-Charlotte von Brevern, Monica C. Hollstein, Helen M. Cawley, Virna M. G. De Benedetti, William P. Bennett, Linda Liang, An-Guang He, Simin M. Zhu, Thomas Tursz, Nicolas Janin, and Glenwood E. Trivers
Cancer Res 1996 56: 4917-4921. [Abstract] [PDF]  

Phenolphthalein Exposure Causes Multiple Carcinogenic Effects in Experimental Model Systems

June K. Dunnick and James R. Hailey
Cancer Res 1996 56: 4922-4926. [Abstract] [PDF]  

Alterations in H-ras1 Promoter Conformation during N-Nitroso-N-methylurea-induced Mammary Carcinogenesis and Pregnancy

Zhuang Jin, Benoit Houle, Andrei M. Mikheev, Rita S. Cha, and Helmut Zarbl
Cancer Res 1996 56: 4927-4935. [Abstract] [PDF]  

Sphingomyelin Consumption Suppresses Aberrant Colonic Crypt Foci and Increases the Proportion of Adenomas versus Adenocarcinomas in CF1 Mice Treated with 1,2-Dimethylhydrazine: Implications for Dietary Sphingolipids and Colon Carcinogenesis

Eva M. Schmelz, Dirck L. Dillehay, Sonji K. Webb, Alex Reiter, Jeanette Adams, and Alfred H. Merrill, Jr.
Cancer Res 1996 56: 4936-4941. [Abstract] [PDF]  

Loss of Retinoic Acid Receptors in Mouse Skin and Skin Tumors Is Associated with Activation of the ras^Ha Oncogene and High Risk for Premalignant Progression

Nadine Darwiche, Giorgio Scita, Carol Jones, Susan Rutberg, Eileen Greenwald, Tamar Tennenbaum, Steven J. Collins, Luigi M. De Luca, and Stuart H. Yuspa
Cancer Res 1996 56: 4942-4949. [Abstract] [PDF]  

Endocrinology:

In Vivo Activity of 4-Methylcoumarin-7-O-Sulfamate, a Nonsteroidal, Nonestrogenic Steroid Sulfatase Inhibitor

Atul Purohit, Lawrence W. L. Woo, Anita Singh, Claire J. Winterborn, Barry V. L. Potter, and Michael J. Reed
Cancer Res 1996 56: 4950-4955. [Abstract] [PDF]  

Growth Inhibition of Human Prostate Cells in Vitro by Novel Inhibitors of Androgen Synthesis

Gregory T. Klus, Junji Nakamura, Ji-song Li, Yang-zhi Ling, Chong Son, Jon A. Kemppainen, Elizabeth M. Wilson, and Angela M. H. Brodie
Cancer Res 1996 56: 4956-4964. [Abstract] [PDF]  

Epidemiology:

A C4887A Polymorphism in Exon 7 of Human CYP1A1: Population Frequency, Mutation Linkages, and Impact on Lung Cancer Susceptibility

Ingolf Cascorbi, Jürgen Brockmöller, and Ivar Roots
Cancer Res 1996 56: 4965-4969. [Abstract] [PDF]  

Experimental Therapeutics:

Radioiodination of Internalizing Monoclonal Antibodies Using N-Succinimidyl 5-Iodo-3-Pyridinecarboxylate

Craig J. Reist, Pradeep K. Garg, Kevin L. Alston, Darell D. Bigner, and Michael R. Zalutsky
Cancer Res 1996 56: 4970-4977. [Abstract] [PDF]  

Involvement of Hydrogen Peroxide Production in Erbstatin-induced Apoptosis in Human Small Cell Lung Carcinoma Cells

Siro Simizu, Masaya Imoto, Noriyuki Masuda, Minoru Takada, and Kazuo Umezawa
Cancer Res 1996 56: 4978-4982. [Abstract] [PDF]  

Substance P-induced Mitogenesis in Human Astrocytoma Cells Correlates with Activation of the Mitogen-activated Protein Kinase Signaling Pathway

Weihua Luo, Taraneh R. Sharif, and Mohammed Sharif
Cancer Res 1996 56: 4983-4991. [Abstract] [PDF]  

MDR1 Substrates/Modulators Protect against ß-Estradiol-17ß-D-Glucuronide Cholestasis in Rat Liver

Yong Liu, Liyue Huang, Tim Hoffman, Michael Gosland, and Mary Vore
Cancer Res 1996 56: 4992-4997. [Abstract] [PDF]  

A Chimeric Lym-1/Interleukin 2 Fusion Protein for Increasing Tumor Vascular Permeability and Enhancing Antibody Uptake

Peisheng Hu, Jason L. Hornick, Michelle S. Glasky, Aoyun Yun, Mary N. Milkie, Leslie A. Khawli, Peter M. Anderson, and Alan L. Epstein
Cancer Res 1996 56: 4998-5004. [Abstract] [PDF]  

Immunology:

A Tumor-specific Th2 Clone Initiating Tumor Rejection via Primed CD8⁺ Cytotoxic T-Lymphocyte Activation in Mice

Yuan Shen and Shigeyoshi Fujimoto
Cancer Res 1996 56: 5005-5011. [Abstract] [PDF]  

Molecular Biology and Genetics:

Expression of a Highly Conserved Oncofetal Gene, TA1/E16, in Human Colon Carcinoma and Other Primary Cancers: Homology to Schistosoma Mansoni Amino Acid Permease and Caenorhabditis Elegans Gene Products

Dwayne A. Wolf, Shuo Wang, Marilyn A. Panzica, Nader H. Bassily, and Nancy L. Thompson
Cancer Res 1996 56: 5012-5022. [Abstract] [PDF]  

Loss of the p16^INK4a and p15^INK4b Genes, as well as Neighboring 9p21 Markers, in Sporadic Melanoma

José F. Flores, Graeme J. Walker, J. Michael Glendening, Frank G. Haluska, Javier S. Castresana, Mari-Paz Rubio, Georgina C. Pastorfide, Laurie A. Boyer, Wynn H. Kao, Martha L. Bulyk, Raymond L. Barnhill, Nicholas K. Hayward, David E. Housman, and Jane W. Fountain
Cancer Res 1996 56: 5023-5032. [Abstract] [PDF]  

Resistance to Glucocorticoid-induced Apoptosis in Human T-Cell Acute Lymphoblastic Leukemia CEM-C1 Cells Is Due to Insufficient Glucocorticoid Receptor Expression

Stephan Geley, Bernd L. Hartmann, Monika Hala, Elisabeth M. C. Strasser-Wozak, Klaus Kapelari, and Reinhard Kofler
Cancer Res 1996 56: 5033-5038. [Abstract] [PDF]  

Evidence for Two Tumor Suppressor Loci Associated with Proximal Chromosome 9p to q and Distal Chromosome 9q in Bladder Cancer and the Initial Screening for GAS1 and PTC Mutations

Anne R. Simoneau, Charles H. Spruck, III, Mirella Gonzalez-Zulueta, Mark L. Gonzalgo, Matilda F. Chan, Yvonne C. Tsai, Michael Dean, Kenneth Steven, Thomas Horn, and Peter A. Jones
Cancer Res 1996 56: 5039-5043. [Abstract] [PDF]  

High-Density Mapping of Chromosomal Arm 1q in Renal Collecting Duct Carcinoma: Region of Minimal Deletion at 1q32.1–32.2

Gabriel Steiner, Paul Cairns, Thomas J. Polascik, Fray F. Marshall, Jonathan I. Epstein, David Sidransky, and Mark Schoenberg
Cancer Res 1996 56: 5044-5046. [Abstract] [PDF]  

Genetic Regulation of Traits Essential for Spontaneous Ovarian Teratocarcinogenesis in Strain LT/Sv Mice: Aberrant Meiotic Cell Cycle, Oocyte Activation, and Parthenogenetic Development

John J. Eppig, Karen Wigglesworth, Don S. Varnum, and Joseph H. Nadeau
Cancer Res 1996 56: 5047-5054. [Abstract] [PDF]  

Tumor Biology:

Posttranscriptional Regulation of p21^WAF1/CIP1 Expression in Human Breast Carcinoma Cells

Xiao-Su Li, Arun K. Rishi, Zhi-Ming Shao, Marcia I. Dawson, Ling Jong, Braham Shroot, Uwe Reichert, Jose Ordonez, and Joseph A. Fontana
Cancer Res 1996 56: 5055-5062. [Abstract] [PDF]  

Expression of Tissue Factor in Tumor Stroma Correlates with Progression to Invasive Human Breast Cancer: Paracrine Regulation by Carcinoma Cellderived Members of the Transforming Growth Factor ß Family

Julie A. Vrana, Michael T. Stang, Joseph P. Grande, and Michael J. Getz
Cancer Res 1996 56: 5063-5070. [Abstract] [PDF]  

Human Prostate Carcinoma Cells Express Functional IIbß3 Integrin

Mohit Trikha, Jozsef Timar, Steven K. Lundy, Karoly Szekeres, Keqin Tang, David Grignon, Arthur T. Porter, and Kenneth V. Honn
Cancer Res 1996 56: 5071-5078. [Abstract] [PDF]  

A Common Mutant Epidermal Growth Factor Receptor Confers Enhanced Tumorigenicity on Human Glioblastoma Cells by Increasing Proliferation and Reducing Apoptosis

Motoo Nagane, Frank Coufal, Hong Lin, Oliver Bögler, Webster K. Cavenee, and H-J. Su Huang
Cancer Res 1996 56: 5079-5086. [Abstract] [PDF]  

Virology:

Transformation by Human Papillomavirus 16 E6 and E7: Role of the Insulin-like Growth Factor 1 Receptor

Michael A. Steller, Zhiqiang Zou, John T. Schiller, and Renato Baserga
Cancer Res 1996 56: 5087-5091. [Abstract] [PDF]  

Frequent Loss of Chromosome 8p in Hepatitis B Virus-positive Hepatocellular Carcinomas from China

Sherry A. Becker, Yi-Zhong Zhou, and Betty L. Slagle
Cancer Res 1996 56: 5092-5097. [Abstract] [PDF]  

Letter to the Editor:

Correspondence re: M. R. Teixeira et al., Karyotypic Comparisons of Multiple Tumorous and Macroscopically Normal Surrounding Tissue Samples from Patients with Breast Cancer. Cancer Res., 56: 855–859, 1996

J. Mark Cline
Cancer Res 1996 56: 5098-5097. [PDF]  

Reply:

Correspondence re: M. R. Teixeira et al., Karyotypic Comparisons of Multiple Tumorous and Macroscopically Normal Surrounding Tissue Samples from Patients with Breast Cancer. Cancer Res., 56: 855–859, 1996—Reply

Manuel R. Teixeira, Sverre Heim, Nikos Pandis, Georgia Bardi, and Johan A. Andersen
Cancer Res 1996 56: 5098 [PDF]  

Articles:

Announcements

Cancer Res 1996 56: 5099-5101. [PDF]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.