Perspectives in Cancer Research:

Tumor Malignancy Defined by Aberrant Glycosylation and Sphingo(glyco)lipid Metabolism

Sen-itiroh Hakomori
Cancer Res 1996 56: 5309-5318. [Abstract] [PDF]  

Advances in Brief:

Inhibition of Human Breast Cancer Metastasis in Nude Mice by Synthetic Glycoamines

Gennadi V. Glinsky, Janet E. Price, Vladislav V. Glinsky, Valery V. Mossine, Galina Kiriakova, and John B. Metcalf
Cancer Res 1996 56: 5319-5324. [Abstract] [PDF]  

Distinct Patterns of Chromosomal Alterations in High- and Low-Grade Head and Neck Squamous Cell Carcinomas

Ulrike Bockmühl, Anke Schwendel, Manfred Dietel, and Iver Petersen
Cancer Res 1996 56: 5325-5329. [Abstract] [PDF]  

Enhanced Coexpression of Thioredoxin and High Mobility Group Protein 1 Genes in Human Hepatocellular Carcinoma and the Possible Association with Decreased Sensitivity to Cisplatin

Naoyuki Kawahara, Toshiya Tanaka, Akira Yokomizo, Hiroki Nanri, Mayumi Ono, Morimasa Wada, Kimitoshi Kohno, Kenji Takenaka, Keizo Sugimachi, and Michihiko Kuwano
Cancer Res 1996 56: 5330-5333. [Abstract] [PDF]  

Asbestos Causes Stimulation of the Extracellular Signal-regulated Kinase 1 Mitogen-activated Protein Kinase Cascade after Phosphorylation of the Epidermal Growth Factor Receptor

Christine L. Zanella, James Posada, Thomas R. Tritton, and Brooke T. Mossman
Cancer Res 1996 56: 5334-5338. [Abstract] [PDF]  

Microsatellite Instability in Aberrant Crypt Foci from Human Colons

Christopher D. Heinen, Narayan Shivapurkar, Zhaocheng Tang, Joanna Groden, and Oliver Alabaster
Cancer Res 1996 56: 5339-5341. [Abstract] [PDF]  

Genotoxicity of Human Mammary Lipid

Francis L. Martin, Paul L. Carmichael, Christopher Crofton-Sleigh, Stanley Venitt, David H. Phillips, and Philip L. Grover
Cancer Res 1996 56: 5342-5346. [Abstract] [PDF]  

Radiation Therapy and Hyperthermia Improve the Oxygenation of Human Soft Tissue Sarcomas

David M. Brizel, Sean P. Scully, John M. Harrelson, Lester J. Layfield, Richard K. Dodge, H. Cecil Charles, Thaddeus V. Samulski, Leonard R. Prosnitz, and Mark W. Dewhirst
Cancer Res 1996 56: 5347-5350. [Abstract] [PDF]  

Double Knockout of the MRP Gene Leads to Increased Drug Sensitivity in Vitro

Aurelio Lorico, Germana Rappa, Richard A. Flavell, and Alan C. Sartorelli
Cancer Res 1996 56: 5351-5355. [Abstract] [PDF]  

IGF2 but not H19 Shows Loss of Imprinting in Human Glioma

Shinji Uyeno, Yasuhiro Aoki, Masayuki Nata, Kaoru Sagisaka, Takamasa Kayama, Takashi Yoshimoto, and Tetsuya Ono
Cancer Res 1996 56: 5356-5359. [Abstract] [PDF]  

Germline BRCA2 Gene Mutations in Patients with Apparently Sporadic Pancreatic Carcinomas

Michael Goggins, Mieke Schutte, Jia Lu, Christopher A. Moskaluk, Craig L. Weinstein, Gloria M. Petersen, Charles J. Yeo, Charles E. Jackson, Henry T. Lynch, Ralph H. Hruban, and Scott E. Kern
Cancer Res 1996 56: 5360-5364. [Abstract] [PDF]  

p53-null Cells Are More Sensitive to Ultraviolet Light Only in the Presence of Caffeine

Jeffrey S. DeFrank, Wei Tang, and Simon N. Powell
Cancer Res 1996 56: 5365-5368. [Abstract] [PDF]  

Effect of PD 098059, a Specific Inhibitor of Mitogen-activated Protein Kinase Kinase, on Urokinase Expression and in Vitro Invasion

Christian Simon, Jose Juarez, Garth L. Nicolson, and Douglas Boyd
Cancer Res 1996 56: 5369-5374. [Abstract] [PDF]  

Mismatch Repair Mutations Override Alkyltransferase in Conferring Resistance to Temozolomide but not to 1,3-Bis(2-chloroethyl)nitrosourea

Lili Liu, Sanford Markowitz, and Stanton L. Gerson
Cancer Res 1996 56: 5375-5379. [Abstract] [PDF]  

Construction of a Representative cDNA Library from Prostatic Intraepithelial Neoplasia

David B. Krizman, Rodrigo F. Chuaqui, Paul S. Meltzer, Jeffrey M. Trent, Paul H. Duray, W. Marston Linehan, Lance A. Liotta, and Michael R. Emmert-Buck
Cancer Res 1996 56: 5380-5383. [Abstract] [PDF]  

Carcinogenesis:

Induction of Cell Growth Regulatory Genes by p53

Stephen L. Madden, Elizabeth A. Galella, Deborah Riley, Arthur H. Bertelsen, and Gary A. Beaudry
Cancer Res 1996 56: 5384-5390. [Abstract] [PDF]  

Up-Regulation of Vascular Endothelial Growth Factor/Vascular Permeability Factor in Mouse Skin Carcinogenesis Correlates with Malignant Progression State and Activated H-ras Expression Levels

Fernando Larcher, Ana I. Robles, Hebe Duran, Rodolfo Murillas, Miguel Quintanilla, Amparo Cano, Claudio J. Conti, and José Luis Jorcano
Cancer Res 1996 56: 5391-5396. [Abstract] [PDF]  

Endocrinology:

Expression of Human Glandular Kallikrein, hK2, in Mammalian Cells

Abhay Kumar, Amita S. Goel, Timothy M. Hill, Stephen D. Mikolajczyk, Lisa S. Millar, Kristine Kuus-Reichel, and Mohammad S. Saedi
Cancer Res 1996 56: 5397-5402. [Abstract] [PDF]  

Novel Estrogenic Action of the Pesticide Residue ß-Hexachlorocyclohexane in Human Breast Cancer Cells

Rosemary Steinmetz, Peter C. M. Young, Andrea Caperell-Grant, Edward A. Gize, Burra V. Madhukar, Nira Ben-Jonathan, and Robert M. Bigsby
Cancer Res 1996 56: 5403-5409. [Abstract] [PDF]  

Epidemiology:

An Investigation of Multiple Biomarkers among Workers Exposed to Styrene and Styrene-7,8-oxide

Stephen M. Rappaport, Karen Yeowell-O'Connell, William Bodell, Janice W. Yager, and Elaine Symanski
Cancer Res 1996 56: 5410-5416. [Abstract] [PDF]  

Experimental Therapeutics:

Oligodendrocytes in the Adult Rat Spinal Cord Undergo Radiation-induced Apoptosis

Yu-Qing Li, Venita Jay, and C. Shun Wong
Cancer Res 1996 56: 5417-5422. [Abstract] [PDF]  

Retroviral Delivery and Tetracycline-dependent Expression of IL-1ß-converting Enzyme (ICE) in a Rat Glioma Model Provides Controlled Induction of Apoptotic Death in Tumor Cells

John S. Yu, Miguel Sena-Esteves, Werner Paulus, Xandra O. Breakefield, and Steven A. Reeves
Cancer Res 1996 56: 5423-5427. [Abstract] [PDF]  

Therapeutic Effect of m-[¹³¹I]- and m-[¹²⁵I]Iodobenzylguanidine on Neuroblastoma Multicellular Tumor Spheroids of Different Sizes

Wolfgang Weber, Judith Weber, and Reingard Senekowitsch-Schmidtke
Cancer Res 1996 56: 5428-5434. [Abstract] [PDF]  

Evidence for Cytoplasmic P-Glycoprotein Location Associated with Increased Multidrug Resistance and Resistance to Chemosensitizers

Mohammad R. Abbaszadegan, Anne E. Cress, Bernard W. Futscher, William T. Bellamy, and William S. Dalton
Cancer Res 1996 56: 5435-5442. [Abstract] [PDF]  

Immunology:

CD3-CD28 Costimulation as a Means to Avoiding T Cell Preactivation in Bispecific Monoclonal Antibody-based Treatment of Ovarian Carcinoma

Alessandra Mazzoni, Delia Mezzanzanica, Gundram Jung, Hans Wolf, Maria I. Colnaghi, and Silvana Canevari
Cancer Res 1996 56: 5443-5449. [Abstract] [PDF]  

Molecular Biology and genetics:

Recovery of Normal DNA Repair and Mutagenesis in Trichothiodystrophy Cells after Transduction of the XPD Human Gene

Claire Marionnet, Xavier Quilliet, Annie Benoit, Jacques Armier, Alain Sarasin, and Anne Stary
Cancer Res 1996 56: 5450-5456. [Abstract] [PDF]  

Genotoxicity of Aflatoxin B₁: Evidence for a Recombination-mediated Mechanism in Saccharomyces cerevisiae

Christian Sengstag, Béatrice Weibel, and Michael Fasullo
Cancer Res 1996 56: 5457-5465. [Abstract] [PDF]  

Identification of Seven New BRCA1 Germline Mutations in Italian Breast and Breast/Ovarian Cancer Families

Marco Montagna, Maria Santacatterina, Barbara Corneo, Chiara Menin, Olga Serova, Gilbert M. Lenoir, Luigi Chieco-Bianchi, and Emma D'Andrea
Cancer Res 1996 56: 5466-5469. [Abstract] [PDF]  

Microsatellite Instability Is Associated with the Histological Features of the Tumor in Nonfamilial Colorectal Cancer

Mauro Risio, Gigliola Reato, Paola Francia di Celle, Marco Fizzotti, Francesco Paolo Rossini, and Robin Foà
Cancer Res 1996 56: 5470-5474. [Abstract] [PDF]  

The p16-cyclin D/Cdk4-pRb Pathway as a Functional Unit Frequently Altered in Melanoma Pathogenesis

Jirina Bartkova, Jiri Lukas, Per Guldberg, Jan Alsner, Alexei F. Kirkin, Jesper Zeuthen, and Jiri Bartek
Cancer Res 1996 56: 5475-5483. [Abstract] [PDF]  

High Levels of Allele Loss at the FHIT and ATM Genes in Non-Comedo Ductal Carcinoma in Situ and Grade I Tubular Invasive Breast Cancers

Somai Man, Ian O. Ellis, Mark Sibbering, Roger W. Blamey, and J. David Brook
Cancer Res 1996 56: 5484-5489. [Abstract] [PDF]  

Reversal of the in Vivo Metastatic Phenotype of Human Tumor Cells by an Anti-CAPL (mts1) Ribozyme

Gunhild Mari Mælandsmo, Eivind Hovig, Martina Skrede, Olav Engebraaten, Vivi Ann Flørenes, Ola Myklebost, Mariam Grigorian, Eugene Lukanidin, Kevin J. Scanlon, and Øystein Fodstad
Cancer Res 1996 56: 5490-5498. [Abstract] [PDF]  

Tumor Biology:

Interleukin (IL)-10 and IL-6 Are Produced in Vivo by Non-Hodgkin's Lymphoma Cells and Act as Cooperative Growth Factors

Nathalie Voorzanger, Robert Touitou, Eric Garcia, Henry-Jacques Delecluse, Françoise Rousset, Irène Joab, Marie C. Favrot, and Jean-Yves Blay
Cancer Res 1996 56: 5499-5505. [Abstract] [PDF]  

Induction of Fibroblast Gelatinase B Expression by Direct Contact with Cell Lines Derived from Primary Tumor but not from Metastases

Jean-Pierre Segain, Jean Harb, Marc Grégoire, Khaled Meflah, and Jean Menanteau
Cancer Res 1996 56: 5506-5512. [Abstract] [PDF]  

Transition to Tetraploidy in 1,25-Dihydroxyvitamin D₃-resistant HL60 Cells Is Preceded by Reduced Growth Factor Dependence and Constitutive Up-Regulation of Sp1 and AP-1 Transcription Factors

George P. Studzinski, Bina Rathod, Jie Rao, Ahmed Kheir, Howard J. Wajchman, Fan Zhang, Janet B. Finan, and Peter C. Nowell
Cancer Res 1996 56: 5513-5521. [Abstract] [PDF]  

Fluctuations in Red Cell Flux in Tumor Microvessels Can Lead to Transient Hypoxia and Reoxygenation in Tumor Parenchyma

Hiroyuki Kimura, Rod D. Braun, Edgardo T. Ong, Richard Hsu, Timothy W. Secomb, Demetrios Papahadjopoulos, Keelung Hong, and Mark W. Dewhirst
Cancer Res 1996 56: 5522-5528. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1996 56: 5529-5531. [PDF]  

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