Advances in Brief:

Presence of Potent Transcriptional Activation Domains in the Predisposing Tuberous Sclerosis (Tsc2) Gene Product of the Eker Rat Model

Haruo Tsuchiya, Kenji Orimoto, Toshiyuki Kobayashi, and Okio Hino
Cancer Res 1996 56: 429-433. [Abstract] [PDF]  

Histone H3 Messenger RNA in Situ Hybridization Correlates with in Vivo Bromodeoxyuridine Labeling of S-Phase Cells in Rat Colonic Epithelium

Hideyuki Konishi, Gideon Steinbach, Nicholas H. A. Terry, J. Jack Lee, Joel A. Dubin, Gary A. Glober, Kinya Fujita, Dave Spaulding, Laura Cass, and Walter N. Hittelman
Cancer Res 1996 56: 434-437. [Abstract] [PDF]  

Cleavage of Retinoblastoma Protein during Apoptosis: An Interleukin 1ß-converting Enzyme-like Protease as Candidate

Bing An and Q. Ping Dou
Cancer Res 1996 56: 438-442. [Abstract] [PDF]  

Elevation of Interferon ß-inducible Proteins in Ataxia Telangiectasia Cells

Chanda Siddoo-Atwal, Arthur L. Haas, and Miriam P. Rosin
Cancer Res 1996 56: 443-447. [Abstract] [PDF]  

A New Member of the Proprotein Convertase Gene Family (LPC) Is Located at a Chromosome Translocation Breakpoint in Lymphomas

Joanne Meerabux, Marie-Laure Yaspo, Anton J. Roebroek, Wim J. M. Van de Ven, T. Andrew Lister, and Bryan D. Young
Cancer Res 1996 56: 448-451. [Abstract] [PDF]  

Detection of 1,N²-Propanodeoxyguanosine Adducts as Potential Endogenous DNA Lesions in Rodent and Human Tissues

Raghu G. Nath, Joseph E. Ocando, and Fung-Lung Chung
Cancer Res 1996 56: 452-456. [Abstract] [PDF]  

A Matrix Attachment Region (MAR)-binding Activity Due to a p114 Kilodalton Protein Is Found Only in Human Breast Carcinomas and Not in Normal and Benign Breast Disease Tissues

Junn Yanagisawa, Jiro Ando, Jun Nakayama, Yoshinori Kohwi, and Terumi Kohwi-Shigematsu
Cancer Res 1996 56: 457-462. [Abstract] [PDF]  

Accelerated Growth of Melanomas after Specific Immune Destruction of Tumor Stroma in a Mouse Model

Beatrice Mintz and Willys K. Silvers
Cancer Res 1996 56: 463-466. [Abstract] [PDF]  

Interleukin 12 Potentiates the Curative Effect of a Vaccine Based on Interleukin 2-transduced Tumor Cells

Maddalena Vagliani, Monica Rodolfo, Federica Cavallo, Mariella Parenza, Cecilia Melani, Giorgio Parmiani, Guido Forni, and Mario P. Colombo
Cancer Res 1996 56: 467-470. [Abstract] [PDF]  

Germ Line Mutation at BRCA1 Affects the Histoprognostic Grade in Hereditary Breast Cancer

François Eisinger, Dominique Stoppa-Lyonnet, Michel Longy, Fabienne Kerangueven, Tetsuro Noguchi, Christiane Bailly, Anne Vincent-Salomon, Jocelyn Jacquemier, Daniel Birnbaum, and Hagay Sobol
Cancer Res 1996 56: 471-474. [Abstract] [PDF]  

Role of p21 in Prostaglandin A₂-mediated Cellular Arrest and Death

Myriam Gorospe and Nikki J. Holbrook
Cancer Res 1996 56: 475-479. [Abstract] [PDF]  

Loss of H19 Imprinting in Esophageal Cancer

Kenji Hibi, Hajime Nakamura, Atsushi Hirai, Yoshihiro Fujikake, Yasushi Kasai, Seiji Akiyama, Katsuki Ito, and Hiroshi Takagi
Cancer Res 1996 56: 480-482. [Abstract] [PDF]  

Inhibition of Tumor Promoter-induced Transformation by Retinoids That Transrepress AP-1 without Transactivating Retinoic Acid Response Element

Jian-Jian Li, Zigang Dong, Marcia I. Dawson, and Nancy H. Colburn
Cancer Res 1996 56: 483-489. [Abstract] [PDF]  

Homozygous Deletion Map at 18q21.1 in Pancreatic Cancer

Stephan A. Hahn, A. T. M. Shamsul Hoque, Christopher A. Moskaluk, Luis T. da Costa, Mieke Schutte, Ester Rozenblum, Albert B. Seymour, Craig L. Weinstein, Charles J. Yeo, Ralph H. Hruban, and Scott E. Kern
Cancer Res 1996 56: 490-494. [Abstract] [PDF]  

Effects of Endogenously Activated Transforming Growth Factor-ß on Growth and Differentiation of Retinoic Acid-treated HL-60 Cells

Irene Nunes, Soichi Kojima, and Daniel B Rifkin
Cancer Res 1996 56: 495-499. [Abstract] [PDF]  

Cell Cycle Synchrony Unmasks the Influence of p53 Function on Radiosensitivity of Human Glioblastoma Cells

Garret L. Yount, Daphne A. Haas-Kogan, Charlie A. Vidair, Martin Haas, William C. Dewey, and Mark A. Israel
Cancer Res 1996 56: 500-506. [Abstract] [PDF]  

Mechanisms of Interleukin-2-induced Hepatic Toxicity

Koji Nakagawa, Frederick N. Miller, David E. Sims, Alex B. Lentsch, Masaru Miyazaki, and Michael J. Edwards
Cancer Res 1996 56: 507-510. [Abstract] [PDF]  

Biochemistry and Biophysics:

Impairment of Sodium Pump and Na⁺/H⁺ Antiport in Erythrocytes Isolated from Cancer Patients

André L. Borg, Philippe M. Gallice, Hervé N. Kovacic, Adriana E. Nicoara, Roger G. Favre, and Aimé D. Crevat
Cancer Res 1996 56: 511-514. [Abstract] [PDF]  

Temporary ex Vivo Inhibition of the Expression of the Human Oncogene HER2 (NEU) by a Triple Helix-forming Oligonucleotide

Horea Porumb, Hervé Gousset, Richard Letellier, Valérie Salle, Dominique Briane, Jany Vassy, Mounira Amor-Gueret, Lucien Israël, and Eliane Taillandier
Cancer Res 1996 56: 515-522. [Abstract] [PDF]  

Carcinogenesis:

Increased Epithelial Cell Proliferation in the Colon of Patients with Acromegaly

Annemieke Cats, Robin P. F. Dullaart, Jan H. Kleibeuker, Folkert Kuipers, Wim J. Sluiter, Machiel J. Hardonk, and Elisabeth G. E. de Vries
Cancer Res 1996 56: 523-526. [Abstract] [PDF]  

Acetylator Genotype (NAT2)-dependent Formation of Aberrant Crypts in Congenic Syrian Hamsters Administered 3,2'-Dimethyl-4-aminobiphenyl

Yi Feng, Rick J. Wagner, Adrian J. Fretland, William K. Becker, A. Marvin Cooley, Theresa P. Pretlow, Kap J. Lee, and David W. Hein
Cancer Res 1996 56: 527-531. [Abstract] [PDF]  

Modulating Effect of Amount and Types of Dietary Fat on Colonic Mucosal Phospholipase A₂, Phosphatidylinositol-specific Phospholipase C Activities, and Cyclooxygenase Metabolite Formation during Different Stages of Colon Tumor Promotion in Male F344 Rats

Chinthalapally V. Rao, Barbara Simi, Tin-Tin Wynn, Kathy Garr, and Bandaru S. Reddy
Cancer Res 1996 56: 532-537. [Abstract] [PDF]  

Experimental Therapeutics:

MKT-077, a Novel Rhodacyanine Dye in Clinical Trials, Exhibits Anticarcinoma Activity in Preclinical Studies Based on Selective Mitochondrial Accumulation

Keizo Koya, Yang Li, Hong Wang, Toshinao Ukai, Noriaki Tatsuta, Masayuki Kawakami, Tadao Shishido, and Lan Bo Chen
Cancer Res 1996 56: 538-543. [Abstract] [PDF]  

Selective Damage to Carcinoma Mitochondria by the Rhodacyanine MKT-077

Josephine S. Modica-Napolitano, Keizo Koya, Ellen Weisberg, Brian T. Brunelli, Yang Li, and Lan Bo Chen
Cancer Res 1996 56: 544-550. [Abstract] [PDF]  

In Vivo Administration of MKT-077 Causes Partial yet Reversible Impairment of Mitochondrial Function

Ellen L. Weisberg, Keizo Koya, Josephine Modica-Napolitano, Yang Li, and Lan Bo Chen
Cancer Res 1996 56: 551-555. [Abstract] [PDF]  

Association between Cisplatin Resistance and Mutation of p53 Gene and Reduced Bax Expression in Ovarian Carcinoma Cell Systems

Paola Perego, Monica Giarola, Sabina C. Righetti, Rosanna Supino, Claudia Caserini, Domenico Delia, Marco A. Pierotti, Toshiyuki Miyashita, John C. Reed, and Franco Zunino
Cancer Res 1996 56: 556-562. [Abstract] [PDF]  

Hyperthermia Enhances Tumor Uptake and Antitumor Efficacy of Thermostable Liposomal Daunorubicin in a Rat Solid Tumor

Chris van Bree, Johan J. Krooshoop, Ron C. Rietbroek, J. Bart A. Kipp, and Piet J. M. Bakker
Cancer Res 1996 56: 563-568. [Abstract] [PDF]  

Clinical Investigation of a Cytostatic Calcium Influx Inhibitor in Patients with Refractory Cancers

Elise C. Kohn, Eddie Reed, Gisele Sarosy, Michaele Christian, Charles J. Link, Kristina Cole, William D. Figg, Patricia A. Davis, Joan Jacob, Barry Goldspiel, and Lance A. Liotta
Cancer Res 1996 56: 569-573. [Abstract] [PDF]  

Reversal of Multidrug Resistance in Vivo by Dietary Administration of the Phytochemical Indole-3-Carbinol

James G. Christensen and Gerald A. LeBlanc
Cancer Res 1996 56: 574-581. [Abstract] [PDF]  

Immunology:

Occasional Memory Cytotoxic T-Cell Responses of Patients with Human Papillomavirus Type 16-positive Cervical Lesions against a Human Leukocyte Antigen-A*0201-restricted E7-encoded Epitope

Maaike E. Ressing, Willemien J. van Driel, Esteban Celis, Alessandro Sette, Remco M. P. Brandt, Marrigje Hartman, Jacqueline D. H. Anholts, Geziena M. T. Schreuder, W. Bram ter Harmsel, Gert Jan Fleuren, Baptist J. Trimbos, W. Martin Kast, and Cornelis J. M. Melief
Cancer Res 1996 56: 582-588. [Abstract] [PDF]  

Molecular Biology and Genetics:

Allelotypes of Primary Cutaneous Melanoma and Benign Melanocytic Nevi

Eugene Healy, Christine E. Belgaid, Minoru Takata, Anders Vahlquist, Ishtiaq Rehman, Howard Rigby, and Jonathan L. Rees
Cancer Res 1996 56: 589-593. [Abstract] [PDF]  

Defective Transfer RNA-Queuine Modification in C3H10T1/2 Murine Fibroblasts Transfected with Oncogenic ras

Claudia J. Morgan, Frank L. Merrill, and R. W. Trewyn
Cancer Res 1996 56: 594-598. [Abstract] [PDF]  

Genomic Localization of Novel Candidate Tumor Suppressor Gene Loci in Human Parathyroid Adenomas

Hideki Tahara, Alison P. Smith, Randall D. Gaz, Vincent L. Cryns, and Andrew Arnold
Cancer Res 1996 56: 599-605. [Abstract] [PDF]  

Allelic Deletion on Chromosome 17p13.3 in Early Ovarian Cancer

Nancy J. Phillips, Michelle R. Ziegler, Diane M. Radford, Keri L. Fair, Todd Steinbrueck, Francisco P. Xynos, and Helen Donis-Keller
Cancer Res 1996 56: 606-611. [Abstract] [PDF]  

Two Distinct Regions of Deletion on the Long Arm of Chromosome 5 in Differentiated Adenocarcinomas of the Stomach

Gen Tamura, Satoshi Ogasawara, Satoshi Nishizuka, Ken Sakata, Chihaya Maesawa, Yasushi Suzuki, Masanori Terashima, Kazuyoshi Saito, and Ryoichi Satodate
Cancer Res 1996 56: 612-615. [Abstract] [PDF]  

Tumor Biology:

Expression of Prokaryotic HhaI DNA Methyltransferase Is Transforming and Lethal to NIH 3T3 Cells

Jianjun Wu, James G. Herman, Geoffrey Wilson, Ree Y. Lee, Ray-Whay Chiu Yen, Mack Mabry, Andrée de Bustros, Barry D. Nelkin, and Stephen B. Baylin
Cancer Res 1996 56: 616-622. [Abstract] [PDF]  

Antiproliferative Responses of Two Human Colon Cancer Cell Lines to Vitamin D₃ Are Differentially Modified by 9-cis-Retinoic Acid

Katherine F. Kane, Michael J. S. Langman, and Graham R. Williams
Cancer Res 1996 56: 623-632. [Abstract] [PDF]  

Human Amniotic Tumor That Induces New Bone Formation in Vivo Produces a Growth-regulatory Activity in Vitro for Osteoblasts Identified as an Extended Form of Basic Fibroblast Growth Factor

Elzbieta Izbicka, Colin Dunstan, Javier Esparza, Chris Jacobs, Massimo Sabatini, and Gregory R. Mundy
Cancer Res 1996 56: 633-636. [Abstract] [PDF]  

Activation of Stress-activated Protein Kinase/c-Jun N-Terminal Kinase by the Non-TPA-type Tumor Promoter Palytoxin

David W. Kuroki, Gary S. Bignami, and Elizabeth V. Wattenberg
Cancer Res 1996 56: 637-644. [Abstract] [PDF]  

Human Telomerase RNA and Telomerase Activity in Immortal Cell Lines and Tumor Tissues

Ariel A. Avilion, Mieczyslaw A. Piatyszek, Jyothi Gupta, Jerry W. Shay, Silvia Bacchetti, and Carol W. Greider
Cancer Res 1996 56: 645-650. [Abstract] [PDF]  

Association of Elevated Levels of Hyaluronidase, a Matrix-degrading Enzyme, with Prostate Cancer Progression

Vinata B. Lokeshwar, Bal L. Lokeshwar, Henri T. Pham, and Norman L. Block
Cancer Res 1996 56: 651-657. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1996 56: 658-660. [PDF]  

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