Advances in Brief:

Endothelin-1 Production and Decreased Endothelin B Receptor Expression in Advanced Prostate Cancer

Joel B. Nelson, Kirk Chan-Tack, Sean P. Hedican, Scott R. Magnuson, Terry J. Opgenorth, G. Steven Bova, and Jonathan W. Simons
Cancer Res 1996 56: 663-668. [Abstract] [PDF]  

Both Cell Proliferation and Apoptosis Increase with Lesion Grade in Cervical Neoplasia but Do Not Correlate with Human Papillomavirus Type

Christina Isacson, Theodore D. Kessis, Lora Hedrick, and Kathleen R. Cho
Cancer Res 1996 56: 669-674. [Abstract] [PDF]  

Retinoic Acid Metabolism and Inhibition of Cell Proliferation: An Unexpected Liaison

Jun Takatsuka, Noriko Takahashi, and Luigi M. De Luca
Cancer Res 1996 56: 675-678. [Abstract] [PDF]  

Suppression of Carcinogenesis in the Intestines of Min Mice by the Soybean-derived Bowman-Birk Inhibitor

Ann R. Kennedy, Yasmin Beazer-Barclay, Kenneth W. Kinzler, and Paul M. Newberne
Cancer Res 1996 56: 679-682. [Abstract] [PDF]  

Immunoperoxidase Detection of 8-Hydroxydeoxyguanosine in Aflatoxin B₁-treated Rat Liver and Human Oral Mucosal Cells

Alicja Yarborough, Yu-Jing Zhang, Ta-Ming Hsu, and Regina M. Santella
Cancer Res 1996 56: 683-688. [Abstract] [PDF]  

A Comparative Study of p53 Gene Mutations, Protein Accumulation, and Response to Cisplatin-based Chemotherapy in Advanced Ovarian Carcinoma

Sabina C. Righetti, Gabriella Della Torre, Silvana Pilotti, Sylvie Ménard, Francesca Ottone, Maria I. Colnaghi, Marco A. Pierotti, Cinzia Lavarino, Mariagrazia Cornarotti, Saro Oriana, Silvia Böhm, Gian Luigi Bresciani, Giambattista Spatti, and Franco Zunino
Cancer Res 1996 56: 689-693. [Abstract] [PDF]  

Adenovirus-mediated Transfer of the p53 Gene Produces Rapid and Generalized Death of Human Glioma Cells via Apoptosis

Candelaria Gomez-Manzano, Juan Fueyo, Athanassios P. Kyritsis, Peter A. Steck, Jack A. Roth, Timothy J. McDonnell, Kim D. Steck, Victor A. Levin, and W. K. Alfred Yung
Cancer Res 1996 56: 694-699. [Abstract] [PDF]  

Expression of rTS Correlates with Altered Growth Regulation of Thymidylate Synthase

Adrian R. Black and Bruce J. Dolnick
Cancer Res 1996 56: 700-705. [Abstract] [PDF]  

In Vitro and Animal Studies of Sodium Thiosulfate as a Potential Chemoprotectant against Carboplatin-induced Ototoxicity

Edward A. Neuwelt, Robert E. Brummett, Laura G. Remsen, Robert A. Kroll, Michael A. Pagel, Christopher I. McCormick, Sydney Guitjens, and Leslie L. Muldoon
Cancer Res 1996 56: 706-709. [Abstract] [PDF]  

Chemoprevention of Spontaneous Intestinal Adenomas in the Apc ^Min Mouse Model by the Nonsteroidal Anti-inflammatory Drug Piroxicam

Russell F. Jacoby, David J. Marshall, Michael A. Newton, Kristian Novakovic, Kendra Tutsch, Carolyn E. Cole, Ronald A. Lubet, Gary J. Kelloff, Ajit Verma, Amy R. Moser, and William F. Dove
Cancer Res 1996 56: 710-714. [Abstract] [PDF]  

Combination Therapy Including a Gelatinase Inhibitor and Cytotoxic Agent Reduces Local Invasion and Metastasis of Murine Lewis Lung Carcinoma

Ian C. Anderson, Margaret A. Shipp, Andrew J. P. Docherty, and Beverly A. Teicher
Cancer Res 1996 56: 715-718. [Abstract] [PDF]  

Localization of an Ovarian Cancer Tumor Suppressor Gene to a 0.5-cM Region between D22S284 and CYP2D, on Chromosome 22q

Emma J. Bryan, Richard H. Watson, Michael Davis, Andrew Hitchcock, William D. Foulkes, and Ian G. Campbell
Cancer Res 1996 56: 719-721. [Abstract] [PDF]  

Hypermethylation-associated Inactivation Indicates a Tumor Suppressor Role for p15^INK4B

James G. Herman, Jin Jen, Adrian Merlo, and Stephen B. Baylin
Cancer Res 1996 56: 722-727. [Abstract] [PDF]  

The t(6;16)(p21;q22) Chromosome Translocation in the LNCaP Prostate Carcinoma Cell Line Results in a tpc/hpr Fusion Gene

Maria Luisa Veronese, Florencia Bullrich, Massimo Negrini, and Carlo M. Croce
Cancer Res 1996 56: 728-732. [Abstract] [PDF]  

G₁ Delay in Cells Overexpressing Prostaglandin Endoperoxide Synthase-2

Raymond N. DuBois, Jinyi Shao, Masahiko Tsujii, Hongmiao Sheng, and R. Daniel Beauchamp
Cancer Res 1996 56: 733-737. [Abstract] [PDF]  

Frequent Loss of Heterozygosity in Region of the KIP1 Locus in Non-Small Cell Lung Cancer: Evidence for a New Tumor Suppressor Gene on the Short Arm of Chromosome 12

Seisho Takeuchi, Naoki Mori, Michiaki Koike, James Slater, Susan Park, Carl W. Miller, Isao Miyoshi, and H. Phillip Koeffler
Cancer Res 1996 56: 738-740. [Abstract] [PDF]  

Refinement of Two Chromosome 11q Regions of Loss of Heterozygosity in Ovarian Cancer

Michael Davis, Andrew Hitchcock, William D. Foulkes, and Ian G. Campbell
Cancer Res 1996 56: 741-744. [Abstract] [PDF]  

Biochemistry and Biophysics:

Fatty Acid Synthase (FAS): A Target for Cytotoxic Antimetabolites in HL60 Promyelocytic Leukemia Cells

Ellen S. Pizer, Fawn D. Wood, Gary R. Pasternack, and Francis P. Kuhajda
Cancer Res 1996 56: 745-751. [Abstract] [PDF]  

Carcinogenesis:

Serum Deprivation, but not Inhibition of Growth per se, Induces a Hypermutable State in Chinese Hamster G12 Cells

Ekaterina I. Goncharova, Arthur Nádas, and Toby G. Rossman
Cancer Res 1996 56: 752-756. [Abstract] [PDF]  

Carcinogenesis in Human Skin Grafted to SCID Mice

Peter W. Soballe, Kathleen T. Montone, Kapaettu Satyamoorthy, Mark Nesbit, and Meenhard Herlyn
Cancer Res 1996 56: 757-764. [Abstract] [PDF]  

Reexpression of Thyroid Peroxidase in a Derivative of an Undifferentiated Thyroid Carcinoma Cell Line by Introduction of Wild-Type p53

James A. Fagin, Shih-Huey Tang, Kazuya Zeki, Roberto Di Lauro, Alfredo Fusco, and Rivkah Gonsky
Cancer Res 1996 56: 765-771. [Abstract] [PDF]  

Chemopreventive Efficacy of Arylalkyl Isothiocyanates and N-Acetylcysteine for Lung Tumorigenesis in Fischer Rats

Fung-Lung Chung, Gary Kelloff, Vernon Steele, Brian Pittman, Edith Zang, Ding Jiao, Jeffrey Rigotty, Chang-In Choi, and Abraham Rivenson
Cancer Res 1996 56: 772-778. [Abstract] [PDF]  

High Levels of AP-2-binding Activity in Cell Lines Infected with Human T-Cell Leukemia Virus Type I: Possible Enhancement of AP-2 Binding by Human T-Cell Leukemia Virus Type 1 tax

Naoki Mori and Diane Prager
Cancer Res 1996 56: 779-782. [Abstract] [PDF]  

Clinical Investigations:

Retrospective Study of the Correlation between the DNA Repair Protein Alkyltransferase and Survival of Brain Tumor Patients Treated with Carmustine

Michael Belanich, Monica Pastor, Terri Randall, Denise Guerra, Jeannie Kibitel, Lori Alas, Ben Li, Marc Citron, Patricia Wasserman, Agnes White, Harmon Eyre, Kurt Jaeckle, Susan Schulman, Dori Rector, Michael Prados, Stephen Coons, William Shapiro, and Daniel Yarosh
Cancer Res 1996 56: 783-788. [Abstract] [PDF]  

Experimental Therapeutics:

Synergism between Cisplatin and Topoisomerase I Inhibitors, NB-506 and SN-38, in Human Small Cell Lung Cancer Cells

Minoru Fukuda, Kazuto Nishio, Fumihiko Kanzawa, Hayato Ogasawara, Tomoyuki Ishida, Hitoshi Arioka, Krzysztof Bojanowski, Mikio Oka, and Nagahiro Saijo
Cancer Res 1996 56: 789-793. [Abstract] [PDF]  

Cytotoxic Effects of Gemcitabine-containing Regimens against Human Non-Small Cell Lung Cancer Cell Lines Which Express Different Levels of p185^neu

Chun-Ming Tsai, Kuo-Ting Chang, Jeou-Yuan Chen, Yuh-Min Chen, Mei-Hui Chen, and Reury-Perng Perng
Cancer Res 1996 56: 794-801. [Abstract] [PDF]  

Preclinical Pharmacology of the Natural Product Anticancer Agent Bryostatin 1, an Activator of Protein Kinase C

Xueshu Zhang, Ruiwen Zhang, Hui Zhao, Hongying Cai, Kimberly A. Gush, Russell G. Kerr, George R. Pettit, and Andrew S. Kraft
Cancer Res 1996 56: 802-808. [Abstract] [PDF]  

Preparation of a Trivalent Antigen-binding Construct Using Polyoxime Chemistry: Improved Biodistribution and Potential for Therapeutic Application

Raymond C. Werlen, Mervi Lankinen, Robin E. Offord, P. August Schubiger, Alan Smith, and Keith Rose
Cancer Res 1996 56: 809-815. [Abstract] [PDF]  

Mitotic Block Induced in HeLa Cells by Low Concentrations of Paclitaxel (Taxol) Results in Abnormal Mitotic Exit and Apoptotic Cell Death

Mary Ann Jordan, Kim Wendell, Sara Gardiner, W. Brent Derry, Hillary Copp, and Leslie Wilson
Cancer Res 1996 56: 816-825. [Abstract] [PDF]  

Immunology:

Selective Loss of Human Leukocyte Antigen Class I Allele Expression in Advanced Renal Cell Carcinoma

Hans-Joachim Luboldt, Britta S. Kubens, Herbert Rübben, and Hans Grosse-Wilde
Cancer Res 1996 56: 826-830. [Abstract] [PDF]  

Molecular Biology and Genetics:

Neutral Endopeptidase: Variable Expression in Human Lung, Inactivation in Lung Cancer, and Modulation of Peptide-induced Calcium Flux

Andrea J. Cohen, Paul A. Bunn, Wilbur Franklin, Catherine Magill-Solc, Christa Hartmann, Barbara Helfrich, Laura Gilman, Joy Folkvord, Karen Helm, and York E. Miller
Cancer Res 1996 56: 831-839. [Abstract] [PDF]  

An Abnormality in the p53 Pathway following -Irradiation in Many Wild-Type p53 Human Melanoma Lines

Insoo Bae, Martin L. Smith, M. Saeed Sheikh, Qimin Zhan, Dominic A. Scudiero, Stephen H. Friend, Patrick M. O'Connor, and Albert J. Fornace, Jr.
Cancer Res 1996 56: 840-847. [Abstract] [PDF]  

Inactivation of the P16^INK4/MTS1 Gene by a Chromosome Translocation t(9;14)(p21–22;q11) in an Acute Lymphoblastic Leukemia of B-Cell Type

Dominique Duro, Olivier Bernard, Véronique Della Valle, Thierry Leblanc, Roland Berger, and Christian-Jacques Larsen
Cancer Res 1996 56: 848-854. [Abstract] [PDF]  

Karyotypic Comparisons of Multiple Tumorous and Macroscopically Normal Surrounding Tissue Samples from Patients with Breast Cancer

Manuel R. Teixeira, Nikos Pandis, Georgia Bardi, Johan A. Andersen, and Severre Heim
Cancer Res 1996 56: 855-859. [Abstract] [PDF]  

Mammaglobin, a Mammary-specific Member of the Uteroglobin Gene Family, Is Overexpressed in Human Breast Cancer

Mark A. Watson and Timothy P. Fleming
Cancer Res 1996 56: 860-865. [Abstract] [PDF]  

Tumor Biology:

Apoptotic Death of Human Leukemic Cells Induced by Vascular Cells Expressing Nitric Oxide Synthase in Response to -Interferon and Tumor Necrosis Factor-

Yong-jian Geng, Kristoffer Hellstrand, Åke Wennmalm, and Göran K. Hansson
Cancer Res 1996 56: 866-874. [Abstract] [PDF]  

Identification of Genes Differentially Expressed in B16 Murine Melanoma Sublines with Different Metastatic Potentials

Tatsuaki Ishiguro, Motowo Nakajima, Mikihiko Naito, Tetsuichiro Muto, and Takashi Tsuruo
Cancer Res 1996 56: 875-879. [Abstract] [PDF]  

Gastrimmune Raises Antibodies That Neutralize Amidated and Glycine-extended Gastrin-17 and Inhibit the Growth of Colon Cancer

Susan A. Watson, Dov Michaeli, Stephen Grimes, Teresa M. Morris, Graham Robinson, Andrea Varro, Timothy A. Justin, and Jack D. Hardcastle
Cancer Res 1996 56: 880-885. [Abstract] [PDF]  

Interleukin 1 and -Interferon Induction of Nitric Oxide Production from Murine Tumor-derived Endothelial Cells

Ming-Jei Chang, Ruth A. Modzelewski, Derick M. Russell, and Candace S. Johnson
Cancer Res 1996 56: 886-891. [Abstract] [PDF]  

Inactivation of p53 Enhances Sensitivity to Multiple Chemotherapeutic Agents

Douglas S. Hawkins, G. William Demers, and Denise A. Galloway
Cancer Res 1996 56: 892-898. [Abstract] [PDF]  

erbB Family Receptor Expression and Growth Regulation in a Newly Isolated Human Breast Cancer Cell Line

Stephen P. Ethier, Kristine E. Kokeny, Jane W. Ridings, and Cheryl A. Dilts
Cancer Res 1996 56: 899-907. [Abstract] [PDF]  

Identification of a Superficial Bladder Tumor-associated Glycoform of the Carcinoembryonic Antigen by Monoclonal Antibody 19A211

Alain Bergeron, Hélène LaRue, and Yves Fradet
Cancer Res 1996 56: 908-915. [Abstract] [PDF]  

Allelic Imbalance at NME1 in Microdissected Primary and Metastatic Human Colorectal Carcinomas Is Frequent but not Associated with Metastasis to Lymph Nodes or Liver

Richard F. Lamb, James J. Going, Ian Pickford, and George D. Birnie
Cancer Res 1996 56: 916-920. [Abstract] [PDF]  

Vascular Endothelial Growth Factor Promotes Tumor Dissemination by a Mechanism Distinct from Its Effect on Primary Tumor Growth

Ostap Melnyk, Marc A. Shuman, and K. Jin Kim
Cancer Res 1996 56: 921-924. [Abstract] [PDF]  

Letters to the Editor:

Correspondence re: G. P. Studzinski and D. C. Moore, Sunlight—Can It Prevent as well as Cause Cancer? Cancer Res., 55: 4014–4022, 1995

Andrzej Slominski
Cancer Res 1996 56: 925 [PDF]  

Correspondence re: G. P. Studzinski and D. C. Moore, Sunlight—Can It Prevent as well as Cause Cancer? Cancer Res., 55: 4014–4022, 1995—Reply

Dorothy C. Moore and George P. Studzinski
Cancer Res 1996 56: 925 [PDF]  

Meeting Report:

Advances in Immunotoxin Biology and Therapy: A Summary of the Fourth International Symposium on Immunotoxins

Arthur E. Frankel, David FitzGerald, Clay Siegall, and Oliver W. Press
Cancer Res 1996 56: 926-932. [PDF]  

Articles:

Announcements

Cancer Res 1996 56: 933-935. [PDF]  

Erratum

Cancer Res 1996 56: 935 [PDF]  

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