Advances in Brief:

Nitrotyrosine Formation, Apoptosis, and Oxidative Damage: Relationships to Nitric Oxide Production in SJL Mice Bearing the RcsX Tumor

Aharon Gal, Snait Tamir, Laura J. Kennedy, Steven R. Tannenbaum, and Gerald N. Wogan
Cancer Res 1997 57: 1823-1828. [Abstract] [PDF]  

Combretastatin A-4, an Agent That Displays Potent and Selective Toxicity toward Tumor Vasculature

Graham G. Dark, Sally A. Hill, Vivien E. Prise, Gillian M. Tozer, George R. Pettit, and Dai J. Chaplin
Cancer Res 1997 57: 1829-1834. [Abstract] [PDF]  

Intracellular ATP Levels Determine Cell Death Fate by Apoptosis or Necrosis

Yutaka Eguchi, Shigeomi Shimizu, and Yoshihide Tsujimoto
Cancer Res 1997 57: 1835-1840. [Abstract] [PDF]  

In Vitro and in Vivo Resistance to Cisplatin in Cells That Have Lost DNA Mismatch Repair

Daniel Fink, Hua Zheng, Sibylle Nebel, Paula S. Norris, Stefan Aebi, Tzu-Ping Lin, Alissar Nehmé, Randolph D. Christen, Martin Haas, Carol L. MacLeod, and Stephen B. Howell
Cancer Res 1997 57: 1841-1845. [Abstract] [PDF]  

GGTI-298 Induces G₀-G₁ Block and Apoptosis Whereas FTI-277 Causes G₂-M Enrichment in A549 Cells

Karine Miquel, Anne Pradines, Jiazhi Sun, Yimin Qian, Andrew D. Hamilton, Saïd M. Sebti, and Gilles Favre
Cancer Res 1997 57: 1846-1850. [Abstract] [PDF]  

The Insulin-like Growth Factor II Receptor Gene Is Mutated in Genetically Unstable Cancers of the Endometrium, Stomach, and Colorectum

Hong Ouyang, Hiromi O. Shiwaku, Hisashi Hagiwara, Ko Miura, Tadayoshi Abe, Yo Kato, Haruo Ohtani, Kenichi Shiiba, Rhonda F. Souza, Stephen J. Meltzer, and Akira Horii
Cancer Res 1997 57: 1851-1854. [Abstract] [PDF]  

Localization of the Multiple Endocrine Neoplasia Type I (MEN1) Gene Based on Tumor Loss of Heterozygosity Analysis

Michael R. Emmert-Buck, Irina A. Lubensky, Qihan Dong, Pachiappan Manickam, Siradanahalli C. Guru, Mary Beth Kester, Shodimu-Emmanuel Olufemi, Sunita Agarwal, A. Lee Burns, Allen M. Spiegel, Francis S. Collins, Stephen J. Marx, Zhengping Zhuang, Lance A. Liotta, Settara C. Chandrasekharappa, and Larisa V. Debelenko
Cancer Res 1997 57: 1855-1858. [Abstract] [PDF]  

Evidence for Genetic Heterogeneity in Familial Wilms' Tumor

Vicki Huff, Chris I. Amos, Edwin C. Douglass, Ross Fisher, Clementina F. Geiser, Carl E. Krill, Frederick P. Li, Louis C. Strong, and J. Matthew McDonald
Cancer Res 1997 57: 1859-1862. [Abstract] [PDF]  

Application of Telomerase Assay for the Screening of Cervical Lesions

Satoru Kyo, Masahiro Takakura, Hiroshi Ishikawa, Toshiyuki Sasagawa, Sinichiro Satake, Masaya Tateno, and Masaki Inoue
Cancer Res 1997 57: 1863-1867. [Abstract] [PDF]  

Adenovirus-mediated Expression of PML Suppresses Growth and Tumorigenicity of Prostate Cancer Cells

Dalin He, Zhao-Mei Mu, Xiaofeng Le, Jer-Tsong Hsieh, Rey-Chen Pong, Leland W. K. Chung, and Kun-Sang Chang
Cancer Res 1997 57: 1868-1872. [Abstract] [PDF]  

Adenovirus Infection Enhances Killing of Melanoma Cells by a Mitotoxin

Kapaettu Satyamoorthy, Peter W. Soballe, Francis Soans, and Meenhard Herlyn
Cancer Res 1997 57: 1873-1876. [Abstract] [PDF]  

Biochemistry and Biophysics:

Potent Pseudosubstrate-based Peptide Inhibitors for p60^c-src Protein Tyrosine Kinase

Qiang Lou, Margaret E. Leftwich, R. Trent McKay, Sydney E. Salmon, Lenka Rychetsky, and Kit S. Lam
Cancer Res 1997 57: 1877-1881. [Abstract] [PDF]  

Ganglioside GD1 Functions in the Adhesion of Metastatic Tumor Cells to Endothelial Cells of the Target Tissue

Takao Taki, Dai Ishikawa, Misa Ogura, Motowo Nakajima, and Shizuo Handa
Cancer Res 1997 57: 1882-1888. [Abstract] [PDF]  

Carcinogenesis:

Characterization of Early Pulmonary Hyperproliferation and Tumor Progression and Their Inhibition by Black Tea in a 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced Lung Tumorigenesis Model with A/J Mice

Guang-yu Yang, Zhi-Yuan Wang, Sungbin Kim, Jie Liao, Darren N. Seril, Xiaoxin Chen, Theresa J. Smith, and Chung S. Yang
Cancer Res 1997 57: 1889-1894. [Abstract] [PDF]  

Clinical Investigations:

DNA Damage-associated Dysregulation of the Cell Cycle and Apoptosis Control in Cells with Germ-line p53 Mutation

Kumiko Goi, Masatoshi Takagi, Satoshi Iwata, Domenico Delia, Minoru Asada, Rosangela Donghi, Yukiko Tsunematsu, Shinpei Nakazawa, Hiroshi Yamamoto, Jun Yokota, Kazuo Tamura, Yoshifumi Saeki, Joji Utsunomiya, Takashi Takahashi, Ryuzo Ueda, Chikashi Ishioka, Mariko Eguchi, Nanao Kamata, and Shuki Mizutani
Cancer Res 1997 57: 1895-1902. [Abstract] [PDF]  

Endocrinology:

Endometrial Hyperplasia and Apoptosis following Neonatal Diethylstilbestrol Exposure and Subsequent Estrogen Stimulation in both Host and Transplanted Hamster Uteri

William J. Hendry, III, Xinglong Zheng, Wendell W. Leavitt, William S. Branham, and Daniel M. Sheehan
Cancer Res 1997 57: 1903-1908. [Abstract] [PDF]  

Physiological Melatonin Inhibition of Human Breast Cancer Cell Growth in Vitro: Evidence for a Glutathione-mediated Pathway

David E. Blask, Sean T. Wilson, and Fred Zalatan
Cancer Res 1997 57: 1909-1914. [Abstract] [PDF]  

Experimental Therapeutics:

Enhanced Therapeutic Effects of Liposome-associated 1-O-Octadecyl-2-O-methyl-sn-glycero-3-phosphocholine

Imran Ahmad, Julius J. Filep, J. Craig Franklin, Andrew S. Janoff, Gregg R. Masters, Judy Pattassery, Andrew Peters, James J. Schupsky, Yan Zha, and Eric Mayhew
Cancer Res 1997 57: 1915-1921. [Abstract] [PDF]  

Tumor Cell Targeting with Antibody-Avidin Complexes and Biotinylated Tumor Necrosis Factor

Monica Moro, Micaela Pelagi, Giulia Fulci, Giovanni Paganelli, Paolo Dellabona, Giulia Casorati, Antonio G. Siccardi, and Angelo Corti
Cancer Res 1997 57: 1922-1928. [Abstract] [PDF]  

Potentiation of Murine MCa-4 Carcinoma Radioresponse by 9-Amino-20(S)-camptothecin

Alexander V. Kirichenko, Tyvin A. Rich, Robert A. Newman, and Elizabeth L. Travis
Cancer Res 1997 57: 1929-1933. [Abstract] [PDF]  

Multiplicity of Biliary Excretion Mechanisms for Irinotecan, CPT-11, and Its Metabolites in Rats

Xiao-Yan Chu, Yukio Kato, and Yuichi Sugiyama
Cancer Res 1997 57: 1934-1938. [Abstract] [PDF]  

Germinal Center-derived Signals Act with Bcl-2 to Decrease Apoptosis and Increase Clonogenicity of Drug-treated Human B Lymphoma Cells

Andrew Walker, Siân T. Taylor, John A. Hickman, and Caroline Dive
Cancer Res 1997 57: 1939-1945. [Abstract] [PDF]  

Enhanced Cyclophosphamide and Ifosfamide Activation in Primary Human Hepatocyte Cultures: Response to Cytochrome P-450 Inducers and Autoinduction by Oxazaphosphorines

Thomas K. H. Chang, Li Yu, Patrick Maurel, and David J. Waxman
Cancer Res 1997 57: 1946-1954. [Abstract] [PDF]  

Immunology:

Improved Biodistribution of ¹²⁵I-labeled Anti-Tac Disulfide-stabilized Fv Fragment by Blocking Its Binding to the Subunit of the Interleukin 2 Receptor in the Circulation with Preinjected Humanized Anti-Tac IgG

Hisataka Kobayashi, Tae M. Yoo, Debra Drumm, Meyoung-Kon Kim, Bao-Fu Sun, Nhat Le, Keith O. Webber, Ira Pastan, Thomas A. Waldmann, Chang H. Paik, and Jorge A. Carrasquillo
Cancer Res 1997 57: 1955-1961. [Abstract] [PDF]  

Molecular Biology and Genetics:

Mutational Activation of pp60^c-src Leads to a Tumorigenic Phenotype in a Preneoplastic Syrian Hamster Embryo Cell Line

Timothy J. Lansing, Bartel F. Turk, Steven B. Kanner, and Tona M. Gilmer
Cancer Res 1997 57: 1962-1969. [Abstract] [PDF]  

A Persistent Double-Strand Break Destabilizes Human DNA in Yeast and Can Lead to G₂ Arrest and Lethality

Craig B. Bennett, Joyce R. Snipe, and Michael A. Resnick
Cancer Res 1997 57: 1970-1980. [Abstract] [PDF]  

Abnormal FHIT Transcripts in Human Breast Carcinomas: A Clinicopathological and Epidemiological Analysis of 61 Japanese Cases

Shin-ichi Hayashi, Keiji Tanimoto, Kyoko Hajiro-Nakanishi, Eijyu Tsuchiya, Masafumi Kurosumi, Yasuhiro Higashi, Kazue Imai, Kenji Suga, and Kei Nakachi
Cancer Res 1997 57: 1981-1985. [Abstract] [PDF]  

Concerted Nonsyntenic Allelic Losses in Hyperploid Hepatocellular Carcinoma as Determined by a High-Resolution Allelotype

Valérie Boige, Pierre Laurent-Puig, Pierre Fouchet, Jean François Fléjou, Geneviève Monges, Pierre Bedossa, Paulette Bioulac-Sage, Frédérique Capron, Anette Schmitz, Sylviane Olschwang, and Gilles Thomas
Cancer Res 1997 57: 1986-1990. [Abstract] [PDF]  

Overexpression of Manganese-containing Superoxide Dismutase Confers Resistance to the Cytotoxicity of Tumor Necrosis Factor and/or Hyperthermia

Jian-Jian Li and Larry W. Oberley
Cancer Res 1997 57: 1991-1998. [Abstract] [PDF]  

Somatic Mutational Mechanisms Involved in Intestinal Tumor Formation in Min Mice

Alex R. Shoemaker, Cindy Luongo, Amy R. Moser, Laurence J. Marton, and William F. Dove
Cancer Res 1997 57: 1999-2006. [Abstract] [PDF]  

Creation of Human Alkyltransferases Resistant to O⁶-Benzylguanine

Fred C. Christians, Brian J. Dawson, Melissa M. Coates, and Lawrence A. Loeb
Cancer Res 1997 57: 2007-2012. [Abstract] [PDF]  

Inhibition of Vascular Endothelial Growth Factor-induced Endothelial Cell Migration by ETS1 Antisense Oligonucleotides

Zhang-qun Chen, Robert J. Fisher, Charles W. Riggs, Johng S. Rhim, and James A. Lautenberger
Cancer Res 1997 57: 2013-2019. [Abstract] [PDF]  

Increasing c-FMS (CSF-1 Receptor) Expression Decreases Retinoic Acid Concentration Needed to Cause Cell Differentiation and Retinoblastoma Protein Hypophosphorylation

Andrew Yen, Rhonda Sturgill, and Susi Varvayanis
Cancer Res 1997 57: 2020-2028. [Abstract] [PDF]  

Identification of a Gene Containing Zinc-Finger Motifs Based on Lost Expression in Malignantly Transformed Rat Ovarian Surface Epithelial Cells

Abbas Abdollahi, Andrew K. Godwin, Paul D. Miller, Lori A. Getts, David C. Schultz, Takahiro Taguchi, Joseph R. Testa, and Thomas C. Hamilton
Cancer Res 1997 57: 2029-2034. [Abstract] [PDF]  

The Human ALL-1/MLL/HRX Antigen Is Predominantly Localized in the Nucleus of Resting and Proliferating Peripheral Blood Mononuclear Cells

Maria-Grazia Ennas, Claudio Sorio, Ralf Greim, Mariella Nieddu, Aldo Scarpa, Simonetta Orlandini, Carlo M. Croce, Georg H. Fey, and Rolf Marschalek
Cancer Res 1997 57: 2035-2041. [Abstract] [PDF]  

Tumor Biology:

Cancer Invasion and Micrometastasis Visualized in Live Tissue by Green Fluorescent Protein Expression

Takashi Chishima, Yohei Miyagi, Xiaoen Wang, Hiroyuki Yamaoka, Hiroshi Shimada, A. R. Moossa, and Robert M. Hoffman
Cancer Res 1997 57: 2042-2047. [Abstract] [PDF]  

Disrupted IGF2 Promoter Control by Silencing of Promoter P1 in Human Hepatocellular Carcinoma

Xuri Li, Zhang Nong, Christina Ekström, Erik Larsson, Hans Nordlinder, Walter J. Hofmann, Christian Trautwein, Margarete Odenthal, Hans Peter Dienes, Tomas J. Ekström, and Peter Schirmacher
Cancer Res 1997 57: 2048-2054. [Abstract] [PDF]  

Expression and Tissue Localization of Membrane-Types 1, 2, and 3 Matrix Metalloproteinases in Human Invasive Breast Carcinomas

Hirohisa Ueno, Hiroyuki Nakamura, Masaki Inoue, Kazushi Imai, Masakuni Noguchi, Hiroshi Sato, Motoharu Seiki, and Yasunori Okada
Cancer Res 1997 57: 2055-2060. [Abstract] [PDF]  

Migration of Highly Aggressive MV3 Melanoma Cells in 3-Dimensional Collagen Lattices Results in Local Matrix Reorganization and Shedding of 2 and ß1 Integrins and CD44

Peter Friedl, Kerstin Maaser, C. Eberhard Klein, Bernd Niggemann, Georg Krohne, and Kurt S. Zänker
Cancer Res 1997 57: 2061-2070. [Abstract] [PDF]  

Human Malignant Thyroid Tumors Displayed Reduced Levels of Transforming Growth Factor ß Receptor Type II Messenger RNA and Protein

Davide Lazzereschi, Annalisa Ranieri, Gabriella Mincione, Silvia Taccogna, Francesco Nardi, and Giulia Colletta
Cancer Res 1997 57: 2071-2076. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1997 57: 2077-2079. [PDF]  

Correction:

Transforming Growth Factor ß1 Suppresses Genomic Instability Independent of a G₁ Arrest, p53, and Rb

Adam B. Glick
Cancer Res 1997 57: 2079 [PDF]  

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