Advances in Brief:

Enhanced Expression of Prostate-specific Membrane Antigen Gene in Prostate Cancer as Revealed by in Situ Hybridization

Masako Kawakami and Jun Nakayama
Cancer Res 1997 57: 2321-2324. [Abstract] [PDF]  

Multidrug Resistance Protein (MRP) Expression in Retinoblastoma Correlates with the Rare Failure of Chemotherapy despite Cyclosporine for Reversal of P-Glycoprotein

Helen S. L. Chan, Ying Lu, Thomas M. Grogan, George Haddad, David R. Hipfner, Susan P. C. Cole, Roger G. Deeley, Victor Ling, and Brenda L. Gallie
Cancer Res 1997 57: 2325-2330. [Abstract] [PDF]  

Patterns of Chromosomal Imbalances in Adenocarcinoma and Squamous Cell Carcinoma of the Lung

Iver Petersen, Michael Bujard, Simone Petersen, Günter Wolf, Almut Goeze, Anke Schwendel, Holger Langreck, Klaus Gellert, Martin Reichel, Kelly Just, Stanislas du Manoir, Thomas Cremer, Manfred Dietel, and Thomas Ried
Cancer Res 1997 57: 2331-2335. [Abstract] [PDF]  

Human patched (PTCH) mRNA Is Overexpressed Consistently in Tumor Cells of Both Familial and Sporadic Basal Cell Carcinoma

Anne Birgitte Undén, Peter G. Zaphiropoulos, Kerstin Bruce, Rune Toftgård, and Mona Ståhle-Bäckdahl
Cancer Res 1997 57: 2336-2340. [Abstract] [PDF]  

Potent Growth Inhibitory Activity of Zidovudine on Cultured Human Breast Cancer Cells and Rat Mammary Tumors

Carston R. Wagner, George Ballato, Abraham O. Akanni, Edward J. McIntee, Richard S. Larson, Shu-ling Chang, and Yusuf J. Abul-Hajj
Cancer Res 1997 57: 2341-2345. [Abstract] [PDF]  

Trioma-based Vaccination against B-Cell Lymphoma Confers Long-Lasting Tumor Immunity

Ralph Mocikat, Michael Selmayr, Stefan Thierfelder, and Horst Lindhofer
Cancer Res 1997 57: 2346-2349. [Abstract] [PDF]  

Frequent Mutation of the E2F-4 Cell Cycle Gene in Primary Human Gastrointestinal Tumors

Rhonda F. Souza, Jing Yin, Kara N. Smolinski, Tong-Tong Zou, Suna Wang, Ying-Qiang Shi, Mun-Gan Rhyu, John Cottrell, John M. Abraham, Kelli Biden, Lisa Simms, Barbara Leggett, G. Steven Bova, Tom Frank, Steven M. Powell, Haruhiko Sugimura, Joanne Young, Noam Harpaz, Kenji Shimizu, Nagahide Matsubara, and Stephen J. Meltzer
Cancer Res 1997 57: 2350-2353. [Abstract] [PDF]  

Expression of CD66a (Human C-CAM) and Other Members of the Carcinoembryonic Antigen Gene Family of Adhesion Molecules in Human Colorectal Adenomas

Peter Nollau, Hanjo Scheller, Maria Kona-Horstmann, Stefan Rohde, Friedrich Hagenmüller, Christoph Wagener, and Michael Neumaier
Cancer Res 1997 57: 2354-2357. [Abstract] [PDF]  

Absence of G_s Gene Mutations in Childhood Thyroid Tumors afte Chernobyl in Contrast to Sporadic Adult Thyroid Neoplasia

Volker Waldmann and Hartmut M. Rabes
Cancer Res 1997 57: 2358-2361. [Abstract] [PDF]  

Expression of the Tumor-associated Gene MN: A Potential Biomarker for Human Renal Cell Carcinoma

James M. McKiernan, Ralph Buttyan, Neil H. Bander, Michael D. Stifelman, Aaron E. Katz, Min-Wei Chen, Carl A. Olsson, and Ihor S. Sawczuk
Cancer Res 1997 57: 2362-2365. [Abstract] [PDF]  

Overexpression of CDC25A and CDC25B in Head and Neck Cancers

Daniela Gasparotto, Roberta Maestro, Sara Piccinin, Tamara Vukosavljevic, Luigi Barzan, Sandro Sulfaro, and Mauro Boiocchi
Cancer Res 1997 57: 2366-2368. [Abstract] [PDF]  

Mutations of the PATCHED Gene in Several Types of Sporadic Extracutaneous Tumors

Jingwu Xie, Ronald L. Johnson, Xiaoli Zhang, John W. Bare, Fred M. Waldman, Philip H. Cogen, Anil G. Menon, Robert S. Warren, Ling-Chun Chen, Matthew P. Scott, and Ervin H. Epstein, Jr.
Cancer Res 1997 57: 2369-2372. [Abstract] [PDF]  

Telomerase Expression in Respiratory Epithelium during the Multistage Pathogenesis of Lung Carcinomas

Kazuo Yashima, Leslie A. Litzky, Larry Kaiser, Thomas Rogers, Stephen Lam, Ignacio I. Wistuba, Sara Milchgrub, Sudhir Srivastava, Mieczyslaw A. Piatyszek, Jerry W. Shay, and Adi F. Gazdar
Cancer Res 1997 57: 2373-2377. [Abstract] [PDF]  

Characterization of the Human Homologue of RAD54: A Gene Located on Chromosome 1p32 at a Region of High Loss of Heterozygosity in Breast Tumors

Debora Rasio, Yoshiki Murakumo, David Robbins, Tim Roth, Aaron Silver, Massimo Negrini, Carl Schmidt, John Burczak, Richard Fishel, and Carlo M. Croce
Cancer Res 1997 57: 2378-2383. [Abstract] [PDF]  

Suppression of Metastasis in Human Breast Carcinoma MDA-MB-435 Cells after Transfection with the Metastasis Suppressor Gene, KiSS-1

Jeong-Hyung Lee and Danny R. Welch
Cancer Res 1997 57: 2384-2387. [Abstract] [PDF]  

Abrogation of Taxol-induced G₂-M Arrest and Apoptosis in Human Ovarian Cancer Cells Grown as Multicellular Tumor Spheroids

Andrea Frankel, Robert Buckman, and Robert S. Kerbel
Cancer Res 1997 57: 2388-2393. [Abstract] [PDF]  

Carcinogenesis:

Metal Ion-dependent Hydrogen Peroxide-induced DNA Damage Is More Sequence Specific than Metal Specific

Henry Rodriguez, Gerald P. Holmquist, Ralph D'Agostino, Jr., Jean Keller, and Steven A. Akman
Cancer Res 1997 57: 2394-2403. [Abstract] [PDF]  

Toxin-induced Increase in Survival Factor Receptors: Modulation of the Threshold for Apoptosis

Catherine C. Boyle and John A. Hickman
Cancer Res 1997 57: 2404-2409. [Abstract] [PDF]  

Vitamin E Inhibits Apoptosis, DNA Modification, and Cancer Incidence Induced by Iron-mediated Peroxidation in Wistar Rat Kidney

Daxian Zhang, Shigeru Okada, Yingyan Yu, Pingdong Zheng, Raizo Yamaguchi, and Hiroshi Kasai
Cancer Res 1997 57: 2410-2414. [Abstract] [PDF]  

Methylnitrosourea-induced Tumorigenesis in MGMT Gene Knockout Mice

Kunihiko Sakumi, Akiko Shiraishi, Seiichiro Shimizu, Teruhisa Tsuzuki, Takatoshi Ishikawa, and Mutsuo Sekiguchi
Cancer Res 1997 57: 2415-2418. [Abstract] [PDF]  

Endocrinology:

Effect of Dietary 2(3)-tert-Butyl-4-hydroxyanisole on the Metabolism and Action of Estradiol and Estrone in Female CD-1 Mice

Bao Ting Zhu, Joseph Lech, Robert T. Rosen, and Allan H. Conney
Cancer Res 1997 57: 2419-2427. [Abstract] [PDF]  

Alteration in -Glutamyl Transpeptidase Activity and Messenger RNA of Human Prostate Carcinoma Cells by Androgen

Maureen O. Ripple, Peter A. Pickhardt, and George Wilding
Cancer Res 1997 57: 2428-2433. [Abstract] [PDF]  

Experimental therapeutics:

The Tyrphostin AG17 Induces Apoptosis and Inhibition of cdk2 Activity in a Lymphoma Cell Line That Overexpresses bcl-2

Giuseppe A. Palumbo, Nirit Yarom, Aviv Gazit, Ziv Sandalon, Michal Baniyash, Nurit Kleinberger-Doron, Alexander Levitzki, and Dina Ben-Yehuda
Cancer Res 1997 57: 2434-2439. [Abstract] [PDF]  

Enhanced Uptake of Doxorubicin into Bronchial Carcinoma: ß-Glucuronidase Mediates Release of Doxorubicin from a Glucuronide Prodrug (HMR 1826) at the Tumor Site

Thomas E. Mürdter, Bernhard Sperker, Kari T. Kivistö, Monika McClellan, Peter Fritz, Godehard Friedel, Albert Linder, Klaus Bosslet, Heikki Toomes, Rainer Dierkesmann, and Heyo K. Kroemer
Cancer Res 1997 57: 2440-2445. [Abstract] [PDF]  

Relationships between the Mitochondrial Permeability Transition and Oxidative Stress during ara-C Toxicity

Karen L. Backway, Ernest A. McCulloch, Sue Chow, and David W. Hedley
Cancer Res 1997 57: 2446-2451. [Abstract] [PDF]  

Apoptosis Primarily Accounts for the Growth-inhibitory Properties of Sulindac Metabolites and Involves a Mechanism That Is Independent of Cyclooxygenase Inhibition, Cell Cycle Arrest, and p53 Induction

Gary A. Piazza, Alanna K. Rahm, Tyler S. Finn, Benjamin H. Fryer, Han Li, Alan L. Stoumen, Rifat Pamukcu, and Dennis J. Ahnen
Cancer Res 1997 57: 2452-2459. [Abstract] [PDF]  

Immunology:

The Effect of Interleukin 12 Desensitization on the Antitumor Efficacy of Recombinant Interleukin 12

Christina M. Coughlin, Maria Wysocka, Giorgio Trinchieri, and William M. F. Lee
Cancer Res 1997 57: 2460-2467. [Abstract] [PDF]  

Bryostatin-1 and IFN- Synergize for the Expression of the Inducible Nitric Oxide Synthase Gene and for Nitric Oxide Production in Murine Macrophages

Lynn S. Taylor, George W. Cox, Giovanni Melillo, Maria Carla Bosco, and Igor Espinoza-Delgado
Cancer Res 1997 57: 2468-2473. [Abstract] [PDF]  

Molecular Biology and Genetics:

A Screening for BRCA1 Mutations in Breast and Breast-Ovarian Cancer Families from the Stockholm Region

Moraima Zelada-Hedman, Brita Wasteson Arver, Antonio Claro, Jindong Chen, Barbro Werelius, Helen Kok, Kerstin Sandelin, Sara Håkansson, Tone Ikdahl Andersen, Åke Borg, Anne-Lise Børresen Dale, and Annika Lindblom
Cancer Res 1997 57: 2474-2477. [Abstract] [PDF]  

Tumor Biology:

The GTPase and Rho GAP Domains of p190, a Tumor Suppressor Protein That Binds the M_r 120,000 Ras GAP, Independently Function as Anti-Ras Tumor Suppressors

Dennis Z. M. Wang, M. S. A. Nur-E-Kamal, Anjali Tikoo, William Montague, and Hiroshi Maruta
Cancer Res 1997 57: 2478-2484. [Abstract] [PDF]  

K-ras Gene Mutations in Normal Colorectal Tissues from K-ras Mutation-positive Colorectal Cancer Patients

Dan Zhu, Phouthone Keohavong, Sydney D. Finkelstein, Patricia Swalsky, Anke Bakker, Joel Weissfeld, Sudhir Srivastava, and Theresa L. Whiteside
Cancer Res 1997 57: 2485-2492. [Abstract] [PDF]  

Quiescence in R3327-G Rat Prostate Tumors after Androgen Ablation

Alan Pollack, Daryl Lim Joon, Catherine S. Wu, Charles Sikes, Masatoshi Hasegawa, Nicholas H. A. Terry, R. Allen White, Gunar K. Zagars, and Marvin L. Meistrich
Cancer Res 1997 57: 2493-2500. [Abstract] [PDF]  

Immunohistochemical Detection of E-Cadherin in Differentiated Thyroid Carcinomas Correlates with Clinical Outcome

Reinhard von Wasielewski, Axel Rhein, Martin Werner, Georg F. W. Scheumann, Henning Dralle, Eyck Pötter, Georg Brabant, and Axel Georgii
Cancer Res 1997 57: 2501-2507. [Abstract] [PDF]  

Role of the p53 Tumor Suppressor Gene in the Tumorigenicity of Burkitt's Lymphoma Cells

Barry W. Cherney, Kishor G. Bhatia, Cecilia Sgadari, Marina I. Gutierrez, Howard Mostowski, Sandra E. Pike, Ghanshyam Gupta, Ian T. Magrath, and Giovanna Tosato
Cancer Res 1997 57: 2508-2515. [Abstract] [PDF]  

Expression and Transcriptional Regulation of the PD-I/Autotaxin Gene in Neuroblastoma

Hiroyuki Kawagoe, Mary L. Stracke, Hajime Nakamura, and Kimihiko Sano
Cancer Res 1997 57: 2516-2521. [Abstract] [PDF]  

The High Affinity IIbß3 Integrin Is Involved in Invasion of Human Melanoma Cells

Mohit Trikha, Jozsef Timar, Steven K. Lundy, Karoly Szekeres, Yinlong Cai, Arthur T. Porter, and Kenneth V. Honn
Cancer Res 1997 57: 2522-2528. [Abstract] [PDF]  

Increased Facilitated Transport of Dehydroascorbic Acid without Changes in Sodium-dependent Ascorbate Transport in Human Melanoma Cells

Charles Spielholz, David W. Golde, Alan N. Houghton, Francisco Nualart, and Juan Carlos Vera
Cancer Res 1997 57: 2529-2537. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1997 57: 2538-2540. [PDF]  

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