Advances in Brief:

Deficient Transforming Growth Factor-ß1 Activation and Excessive Insulin-like Growth Factor II (IGFII) Expression in IGFII Receptor-Mutant Tumors

Suna Wang, Rhonda F. Souza, Dehe Kong, Jing Yin, Kara N. Smolinski, Tong-Tong Zou, Tom Frank, Joanne Young, Kathleen C. Flanders, Haruhiko Sugimura, John M. Abraham, and Stephen J. Meltzer
Cancer Res 1997 57: 2543-2546. [Abstract] [PDF]  

Selective Inhibition of Estrogen-regulated Gene Expression in Vivo by the Pure Antiestrogen ICI 182,780

Salman M. Hyder, Constance Chiappetta, Lata Murthy, and George M. Stancel
Cancer Res 1997 57: 2547-2549. [Abstract] [PDF]  

p53-dependent DNA Damage-induced Apoptosis Requires Fas/APO-1-independent Activation of CPP32ß

Ephraim J. Fuchs, Karen A. McKenna, and Atul Bedi
Cancer Res 1997 57: 2550-2554. [Abstract] [PDF]  

Role of Interleukin 1 and Granulocyte Colony-Stimulating Factor in Photofrin-based Photodynamic Therapy of Rat Rhabdomyosarcoma Tumors

Wil J. A. de Vree, Maria C. Essers, Johan F. Koster, and Wim Sluiter
Cancer Res 1997 57: 2555-2558. [Abstract] [PDF]  

Prostate Attenuated Replication Competent Adenovirus (ARCA) CN706: A Selective Cytotoxic for Prostate-specific Antigen-positive Prostate Cancer Cells

Ron Rodriguez, Eric R. Schuur, Ho Yeong Lim, Gail A. Henderson, Jonathan W. Simons, and Daniel R. Henderson
Cancer Res 1997 57: 2559-2563. [Abstract] [PDF]  

The Immunogenicity of Experimental Tumors Is Strongly Biased by the Expression of Dominant Viral Cytotoxic T-Lymphocyte Epitopes

Giandomenica Iezzi, Loredana Rivolta, Anna Ronchetti, Alfonso Martin-Fontecha, Antonio Rosato, Maria Pia Protti, Maria Grazia Sabbadini, and Matteo Bellone
Cancer Res 1997 57: 2564-2568. [Abstract] [PDF]  

Protective Immunity Induced by Tumor Vaccines Requires Interaction between CD40 and Its Ligand, CD154

Matthew F. Mackey, Jason R. Gunn, Patrick P. Ting, Hitoshi Kikutani, Glen Dranoff, Randolph J. Noelle, and Richard J. Barth, Jr.
Cancer Res 1997 57: 2569-2574. [Abstract] [PDF]  

Loss of Imprinting of the Insulin-like Growth Factor II Gene in Renal Cell Carcinoma

Norio Nonomura, Kazuo Nishimura, Tsuneharu Miki, Nobufumi Kanno, Yasuyuki Kojima, Masayoshi Yokoyama, and Akihiko Okuyama
Cancer Res 1997 57: 2575-2577. [Abstract] [PDF]  

Frequency of Smad Gene Mutations in Human Cancers

Gregory J. Riggins, Kenneth W. Kinzler, Bert Vogelstein, and Sam Thiagalingam
Cancer Res 1997 57: 2578-2580. [Abstract] [PDF]  

Mutations in the Human Homologue of the Drosophila Segment Polarity Gene patched (PTCH) in Sporadic Basal Cell Carcinomas of the Skin and Primitive Neuroectodermal Tumors of the Central Nervous System

Marietta Wolter, Julia Reifenberger, Clemens Sommer, Thomas Ruzicka, and Guido Reifenberger
Cancer Res 1997 57: 2581-2585. [Abstract] [PDF]  

Effect of Folate Deficiency on Mutations at the hprt Locus in Chinese Hamster Ovary Cells Exposed to Monofunctional Alkylating Agents

Richard F. Branda, Amy R. Lafayette, J. Patrick O'Neill, and Janice A. Nicklas
Cancer Res 1997 57: 2586-2588. [Abstract] [PDF]  

Comparisons of CYP2D Messenger RNA Splice Variant Profiles in Human Lung Tumors and Normal Tissues

Zeqi Huang, Michael J. Fasco, Simon Spivack, and Laurence S. Kaminsky
Cancer Res 1997 57: 2589-2592. [Abstract] [PDF]  

Differential Display Cloning Identifies Motility-related Protein (MRP1/CD9) As Highly Expressed in Primary Compared to Metastatic Human Colon Carcinoma Cells

Jean-François Cojot, Isabelle Sordat, Timothée Silvestre, and Bernard Sordat
Cancer Res 1997 57: 2593-2597. [Abstract] [PDF]  

5-Fluorouracil Kinetics in the Interstitial Tumor Space: Clinical Response in Breast Cancer Patients

Markus Müller, Robert M. Mader, Birgit Steiner, Günther G. Steger, Burkhard Jansen, Michael Gnant, Thomas Helbich, Raimund Jakesz, Hans G. Eichler, and Brigitte BlÖchl-Daum
Cancer Res 1997 57: 2598-2601. [Abstract] [PDF]  

The Extracellular Fluid of Solid Carcinomas Contains Immunosuppressive Concentrations of Adenosine

Jonathan Blay, Thomas D. White, and David W. Hoskin
Cancer Res 1997 57: 2602-2605. [Abstract] [PDF]  

Tamoxifen Interferes with the Insulin-like Growth Factor I Receptor (IGF-IR) Signaling Pathway in Breast Cancer Cells

Marina A. Guvakova and Ewa Surmacz
Cancer Res 1997 57: 2606-2610. [Abstract] [PDF]  

A High Ratio of Insulin-like Growth Factor II/Insulin-like Growth Factor Binding Protein 2 Messenger RNA as a Marker for Anaplasia in Meningiomas

Ann-Christin Sandberg Nordqvist, Myriam Peyrard, Helena Pettersson, Tiit Mathiesen, V. Peter Collins, Jan P. Dumanski, and Martin Schalling
Cancer Res 1997 57: 2611-2614. [Abstract] [PDF]  

Cholera Toxin Triggers Apoptosis in Human Lung Cancer Cell Lines

Mustapha Allam, Richard Bertrand, Guiyi Zhang-Sun, Jane Pappas, and Jean Viallet
Cancer Res 1997 57: 2615-2618. [Abstract] [PDF]  

p16^INK4a Promoter Is Hypermethylated at a High Frequency in Esophageal Adenocarcinomas

David J. Wong, Michael T. Barrett, Reinhard Stöger, Mary J. Emond, and Brian J. Reid
Cancer Res 1997 57: 2619-2622. [Abstract] [PDF]  

Carcinogenesis:

Effects of Tea, Decaffeinated Tea, and Caffeine on UVB Light-induced Complete Carcinogenesis in SKH-1 Mice: Demonstration of Caffeine as a Biologically Important Constitutent of Tea

Mou-Tuan Huang, Jian-Guo Xie, Zhi Yuan Wang, Chi-Tang Ho, You-Rong Lou, Chung-Xiou Wang, Gordon C. Hard, and Allan H. Conney
Cancer Res 1997 57: 2623-2629. [Abstract] [PDF]  

Ornithine Decarboxylase Overexpression Is a Sufficient Condition for Tumor Promotion in Mouse Skin

Thomas G. O'Brien, Louis C. Megosh, Gwendolyn Gilliard, and Alejandro Peralta Soler
Cancer Res 1997 57: 2630-2637. [Abstract] [PDF]  

The Putative Tumor Suppressor Gene FHIT at 3p14.2 Is Rarely Affected by Loss of Heterozygosity in Primary Human Brain Tumors

Stephan Frank, Juliane Müller, Jens Plaschke, Matthias Hahn, Jürgen Hampl, Monika Hampl, Steffen Pistorius, Gabriele Schackert, and Hans K. Schackert
Cancer Res 1997 57: 2638-2641. [Abstract] [PDF]  

Endocrinology:

Retinoic Acid Receptor Expression Correlates with Retinoid-induced Growth Inhibition of Human Breast Cancer Cells Regardless of Estrogen Receptor Status

Patrick Fitzgerald, Min Teng, Roshantha A. S. Chandraratna, Richard A. Heyman, and Elizabeth A. Allegretto
Cancer Res 1997 57: 2642-2650. [Abstract] [PDF]  

Expression of Human Prostate-specific Glandular Kallikrein Protein (hK2) in the Breast Cancer Cell Line T47-D

Ming-Li Hsieh, M. Cristine Charlesworth, Marcia Goodmanson, Shaobo Zhang, Thomas Seay, George G. Klee, Donald J. Tindall, and Charles Y. F. Young
Cancer Res 1997 57: 2651-2656. [Abstract] [PDF]  

Experimental Therapeutics:

Synergy between Tamoxifen and Cisplatin in Human Melanoma Cells Is Dependent on the Presence of Antiestrogen-binding Sites

Jeffrey A. Jones, Kathleen D. Albright, Randolph D. Christen, Stephen B. Howell, and Edward F. McClay
Cancer Res 1997 57: 2657-2660. [Abstract] [PDF]  

HSP27 as a Mediator of Confluence-dependent Resistance to Cell Death Induced by Anticancer Drugs

Carmen Garrido, Patrick Ottavi, Annie Fromentin, Arlette Hammann, André-Patrick Arrigo, Bruno Chauffert, and Patrick Mehlen
Cancer Res 1997 57: 2661-2667. [Abstract] [PDF]  

Vitamin E Succinate Inhibits Proliferation of BT-20 Human Breast Cancer Cells: Increased Binding of Cyclin A Negatively Regulates E2F Transactivation Activity

Jennifer M. Turley, Francis W. Ruscetti, Seong-Jin Kim, Tao Fu, F. Victoria Gou, and Maria C. Birchenall-Roberts
Cancer Res 1997 57: 2668-2675. [Abstract] [PDF]  

Ifosfamide Cytotoxicity on Human Tumor and Renal Cells: Role of Chloroacetaldehyde in Comparison to 4-Hydroxyifosfamide

Svenja K. Brüggemann, Jens Kisro, and Thomas Wagner
Cancer Res 1997 57: 2676-2680. [Abstract] [PDF]  

Intratumoral Pharmacokinetics and in Vivo Gene Expression of Naked Plasmid DNA and Its Cationic Liposome Complexes after Direct Gene Transfer

Takehiko Nomura, Shin Nakajima, Kenji Kawabata, Fumiyoshi Yamashita, Yoshinobu Takakura, and Mitsuru Hashida
Cancer Res 1997 57: 2681-2686. [Abstract] [PDF]  

Insulin-like Growth Factor 1 (IGF-1) Alters Drug Sensitivity of HBL100 Human Breast Cancer Cells by Inhibition of Apoptosis Induced by Diverse Anticancer Drugs

Sandra E. Dunn, Rebecca A. Hardman, Frank W. Kari, and J. Carl Barrett
Cancer Res 1997 57: 2687-2693. [Abstract] [PDF]  

Apoptosis in the Subependyma of Young Adult Rats after Single and Fractionated Doses of X-Rays

Chie Shinohara, Glenn T. Gobbel, Kathleen R. Lamborn, Eiji Tada, and John R. Fike
Cancer Res 1997 57: 2694-2702. [Abstract] [PDF]  

Molecular Biology and Genetics:

Chromosome 9p Deletions in Invasive and Noninvasive Nonfunctional Pituitary Adenomas: The Deleted Region Involves Markers Outside of the MTS1 and MTS2 Genes

William E. Farrell, David J. Simpson, John E. Bicknell, Alan J. Talbot, Andrew S. Bates, and Richard N. Clayton
Cancer Res 1997 57: 2703-2709. [Abstract] [PDF]  

Genetic Alterations of p53 and ras Genes in 1,3-Butadiene- and 2',3'-Dideoxycytidine-induced Lymphomas

Shi-Mei Zhuang, Charles Cochran, Tamra Goodrow, Roger W. Wiseman, and Peter Söderkvist
Cancer Res 1997 57: 2710-2714. [Abstract] [PDF]  

A Mutation in the MSH5 Gene Results in Alkylation Tolerance

Sonya Bawa and Wei Xiao
Cancer Res 1997 57: 2715-2720. [Abstract] [PDF]  

A General Role for c-Fos in Cellular Protection against DNA-damaging Carcinogens and Cytostatic Drugs

Bernd Kaina, Simone Haas, and Holger Kappes
Cancer Res 1997 57: 2721-2731. [Abstract] [PDF]  

Ectopic Expression of 2-5A Synthetase in Myeloid Cells Induces Growth Arrest and Facilitates the Appearance of a Myeloid Differentiation Marker

Samuel Salzberg, Tehila Hyman, Hagit Turm, Yosefa Kinar, Yaacov Schwartz, Uri Nir, Flavio Lejbkowicz, and Eliezer Huberman
Cancer Res 1997 57: 2732-2740. [Abstract] [PDF]  

Tumor Biology:

Cadherin-6, a Cell Adhesion Molecule Specifically Expressed in the Proximal Renal Tubule and Renal Cell Carcinoma

Roger Paul, Charles M. Ewing, John C. Robinson, Fray F. Marshall, Keith R. Johnson, Margaret J. Wheelock, and William B. Isaacs
Cancer Res 1997 57: 2741-2748. [Abstract] [PDF]  

Glutathione S-Transferase Expression in Hepatitis B Virus-associated Human Hepatocellular Carcinogenesis

Tianlun Zhou, Alison A. Evans, W. Thomas London, Xiaoling Xia, Heqiang Zou, Fu-min Shen, and Margie L. Clapper
Cancer Res 1997 57: 2749-2753. [Abstract] [PDF]  

Biodistribution of ¹²⁵I-labeled Des(1–3) Insulin-like Growth Factor I in Tumor-bearing Nude Mice and Its in Vitro Catabolism

Bao-Fu Sun, Hisataka Kobayashi, Nhat Le, Tae M. Yoo, Debra Drumm, Chang H. Paik, John G. McAfee, and Jorge A. Carrasquillo
Cancer Res 1997 57: 2754-2759. [Abstract] [PDF]  

Telomerase Activity in Benign Endometrium and Endometrial Carcinoma

Thomas P. Brien, Bhaskar V. S. Kallakury, Charles V. Lowry, Robert A. Ambros, Patrick J. Muraca, John H. Malfetano, and Jeffrey S. Ross
Cancer Res 1997 57: 2760-2764. [Abstract] [PDF]  

Chromosomal Imbalance Maps of Malignant Solid Tumors: A Cytogenetic Survey of 3185 Neoplasms

Fredrik Mertens, Bertil Johansson, Mattias Höglund, and Felix Mitelman
Cancer Res 1997 57: 2765-2780. [Abstract] [PDF]  

Optimal Ratios of Biliary Glycoprotein Isoforms Required for Inhibition of Colonic Tumor Cell Growth

Claire Turbide, Tilo Kunath, Eugene Daniels, and Nicole Beauchemin
Cancer Res 1997 57: 2781-2788. [Abstract] [PDF]  

Two Cytodifferentiation Agent-induced Pathways, Differentiation and Apoptosis, Are Distinguished by the Expression of Human Papillomavirus 16 E7 in Human Bladder Carcinoma Cells

Victoria M. Richon, Paul Russo, Gisela Venta-Perez, Carlos Cordon-Cardo, Richard A. Rifkind, and Paul A. Marks
Cancer Res 1997 57: 2789-2798. [Abstract] [PDF]  

Increased Expression of Low Density Lipoprotein Receptor-related Protein/2-Macroglobulin Receptor in Human Malignant Astrocytomas

Masaaki Yamamoto, Kohichi Ikeda, Kohichi Ohshima, Hitoshi Tsugu, Hideo Kimura, and Masamichi Tomonaga
Cancer Res 1997 57: 2799-2805. [Abstract] [PDF]  

Letters to the Editor:

Correspondence re: C.V. Rao, et al., Inhibition of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced Lymphoma Formation by Oltipraz. Cancer Res., 56: 3395–3398, 1996: Letter

Bill D. Roebuck, Adrianne E. Rogers, and Thomas W. Kensler
Cancer Res 1997 57: 2806 [PDF]  

Correspondence re: C.V. Rao, et al., Inhibition of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced Lymphoma Formation by Oltipraz. Cancer Res., 56: 3395–3398, 1996—Reply

Chinthalapally V. Rao and Bandaru S. Reddy
Cancer Res 1997 57: 2806-2807. [PDF]  

Articles:

Announcements

Cancer Res 1997 57: 2808-2810. [PDF]  

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