Perspectives in Cancer Research:

MCF-7: The First Hormone-responsive Breast Cancer Cell Line

Anait S. Levenson and V. Craig Jordan
Cancer Res 1997 57: 3071-3078. [PDF]  

Advances in Brief:

Insulin-like Growth Factor-I Receptor Overexpression Mediates Cellular Radioresistance and Local Breast Cancer Recurrence after Lumpectomy and Radiation

Bruce C. Turner, Bruce G. Haffty, Latha Narayanan, Jianling Yuan, Pamela A. Havre, Andrew A. Gumbs, Leni Kaplan, Jean-Luc Burgaud, Darryl Carter, Renato Baserga, and Peter M. Glazer
Cancer Res 1997 57: 3079-3083. [Abstract] [PDF]  

Antitumor Activity of the Novel Human Breast Cancer Growth Inhibitor, Mammary-derived Growth Inhibitor-related Gene, MRG

Y. Eric Shi, Jian Ni, Guowei Xiao, Yiliang E. Liu, Alexander Fuchs, Guoliang Yu, Jeffery Su, John M. Cosgrove, Lily Xing, Mei Zhang, Jiyou Li, Bharat B. Aggarwal, Anthony Meager, and Reiner Gentz
Cancer Res 1997 57: 3084-3091. [Abstract] [PDF]  

Histo-Blood Group A/B versus H Status of Human Carcinoma Cells as Correlated with Haptotactic Cell Motility: Approach with A and B Gene Transfection

Daisuke Ichikawa, Kazuko Handa, Donald A. Withers, and Sen-itiroh Hakomori
Cancer Res 1997 57: 3092-3096. [Abstract] [PDF]  

Bcl-2 Protein Inhibits Bufalin-induced Apoptosis through Inhibition of Mitogenactivated Protein Kinase Activation in Human Leukemia U937 Cells

Masahiko Watabe, Nobuko Kawazoe, Yutaka Masuda, Shigeo Nakajo, and Kazuyasu Nakaya
Cancer Res 1997 57: 3097-3100. [Abstract] [PDF]  

Inhibition of Protein Kinase C Prevents Asbestos-induced c-fos and c-jun Proto-Oncogene Expression in Mesothelial Cells

Hua Fung, Timothy R. Quinlan, Yvonne M. W. Janssen, Cynthia R. Timblin, Joanne P. Marsh, Nicholas H. Heintz, Douglas J. Taatjes, Pamela Vacek, Susan Jaken, and Brooke T. Mossman
Cancer Res 1997 57: 3101-3105. [Abstract] [PDF]  

Comparative Analysis of Bone Marrow and Venous Blood Isolates from Gastrointestinal Cancer Patients for the Detection of Disseminated Tumor Cells Using Reverse Transcription PCR

Edlyn Soeth, Ilka Vogel, Christian Röder, Hartmut Juhl, Jan Marxsen, Uwe Krüger, Doris Henne-Bruns, Bernd Kremer, and Holger Kalthoff
Cancer Res 1997 57: 3106-3110. [Abstract] [PDF]  

Expression of Pro Form of Prostate-specific Antigen by Mammalian Cells and Its Conversion to Mature, Active Form by Human Kallikrein 2

Abhay Kumar, Stephen D. Mikolajczyk, Amita S. Goel, Lisa S. Millar, and Mohammad S. Saedi
Cancer Res 1997 57: 3111-3114. [Abstract] [PDF]  

Overexpression of Bcl-x_L Inhibits Ara-C-induced Mitochondrial Loss of Cytochrome c and Other Perturbations That Activate the Molecular Cascade of Apoptosis

Caryn Naekyung Kim, Xiaodong Wang, Yue Huang, Ana Maria Ibrado, Linda Liu, Guofu Fang, and Kapil Bhalla
Cancer Res 1997 57: 3115-3120. [Abstract] [PDF]  

Characterization of the Rat and Mouse Homologues of the BRCA2 Breast Cancer Susceptibility Gene

Kimberly A. McAllister, Astrid Haugen-Strano, Sarah Hagevik, Heather A. Brownlee, N. Keith Collins, P. Andrew Futreal, L. Michelle Bennett, and Roger W. Wiseman
Cancer Res 1997 57: 3121-3125. [Abstract] [PDF]  

Abrogation of the Rb/p16 Tumor-suppressive Pathway in Virtually All Pancreatic Carcinomas

Mieke Schutte, Ralph H. Hruban, Joseph Geradts, Rob Maynard, Werner Hilgers, Sridhar K. Rabindran, Christopher A. Moskaluk, Stephan A. Hahn, Irmgard Schwarte-Waldhoff, Wolff Schmiegel, Stephen B. Baylin, Scott E. Kern, and James G. Herman
Cancer Res 1997 57: 3126-3130. [Abstract] [PDF]  

Aberrant Splicing but not Mutations of TSG101 in Human Breast Cancer

Maxwell P. Lee and Andrew P. Feinberg
Cancer Res 1997 57: 3131-3134. [Abstract] [PDF]  

Characterization of a High Copy Number Amplification at 6q24 in Pancreatic Cancer Identifies c-myb as a Candidate Oncogene

Christine Wallrapp, Friederike Müller-Pillasch, Sabina Solinas-Toldo, Peter Lichter, Helmut Friess, Markus Büchler, Thomas Fink, Guido Adler, and Thomas M. Gress
Cancer Res 1997 57: 3135-3139. [Abstract] [PDF]  

Rapid Analysis of Distinctive CD44 RNA Splicing Preferences That Characterize Colonic Tumors

Steven Goodison, Kazuhiro Yoshida, Takashi Sugino, Anthony Woodman, Hazel Gorham, John Bolodeoku, Martin Kaufmann, and David Tarin
Cancer Res 1997 57: 3140-3144. [Abstract] [PDF]  

Retinoblastoma Binding Factor 1 Site in the Core Promoter Region of the Human RB Gene Is Activated by hGABP/E4TF1

Yoshihiro Sowa, Yuzuru Shiio, Tsuyoshi Fujita, Takuji Matsumoto, Yusuke Okuyama, Daishiro Kato, Jun-ichiro Inoue, Jun-ichi Sawada, Masahide Goto, Hajime Watanabe, Hiroshi Handa, and Toshiyuki Sakai
Cancer Res 1997 57: 3145-3148. [Abstract] [PDF]  

Melanoma-inhibiting Activity, a Novel Serum Marker for Progression of Malignant Melanoma

Anja-Katrin Bosserhoff, Martin Kaufmann, Brigitte Kaluza, Ilse Bartke, Hubert Zirngibl, Rüdiger Hein, Wilhelm Stolz, and Reinhard Buettner
Cancer Res 1997 57: 3149-3153. [Abstract] [PDF]  

Deletions of Chromosome 3p Are Frequent and Early Events in the Pathogenesis of Uterine Cervical Carcinoma

Ignacio I. Wistuba, Franklin D. Montellano, Sara Milchgrub, Arvind K. Virmani, Carmen Behrens, Hailei Chen, Mohsen Ahmadian, Jan A. Nowak, Carolyn Muller, John D. Minna, and Adi F. Gazdar
Cancer Res 1997 57: 3154-3158. [Abstract] [PDF]  

Biochemistry and Biophysics:

Phorbol Ester-induced Cell Surface Association of Matrix Metalloproteinase-9 in Human MCF10A Breast Epithelial Cells

Marta Toth, David C. Gervasi, and Rafael Fridman
Cancer Res 1997 57: 3159-3167. [Abstract] [PDF]  

Carcinogenesis:

Src Tyrosine Kinase Mediates Stimulation of Raf-1 and Mitogen-activated Protein Kinase by the Tumor Promoter Thapsigargin

Tsung-Shu Oliver Chao, Mark Abe, Marc B. Hershenson, Ignatius Gomes, and Marsha Rich Rosner
Cancer Res 1997 57: 3168-3173. [Abstract] [PDF]  

Cell Cycle Response to DNA Damage Differs in Bronchial Epithelial Cells and Lung Fibroblasts

Donna M. Gadbois and Bruce E. Lehnert
Cancer Res 1997 57: 3174-3179. [Abstract] [PDF]  

Targeted Disruption of the Epidermal Growth Factor Receptor Impairs Growth of Squamous Papillomas Expressing the v-ras^Ha Oncogene but Does Not Block in Vitro Keratinocyte Responses to Oncogenic ras

Andrzej A. Dlugosz, Laura Hansen, Christina Cheng, Natalie Alexander, Mitchell F. Denning, David W. Threadgill, Terry Magnuson, Robert J. Coffey, Jr., and Stuart H. Yuspa
Cancer Res 1997 57: 3180-3188. [Abstract] [PDF]  

Aberrant E-Cadherin and -Catenin Expression in Prostate Cancer: Correlation with Patient Survival

Paul J. M. Richmond, Anastasios J. Karayiannakis, Akira Nagafuchi, Amir V. Kaisary, and Massimo Pignatelli
Cancer Res 1997 57: 3189-3193. [Abstract] [PDF]  

Clinical Investigations:

Tumor Necrosis Factor Enhances Parathyroid Hormone-related Protein-induced Hypercalcemia and Bone Resorption without Inhibiting Bone Formation in Vivo

Harry L. Uy, Gregory R. Mundy, Brendan F. Boyce, Beryl M. Story, Colin R. Dunstan, Juan Juan Yin, G. David Roodman, and Theresa A. Guise
Cancer Res 1997 57: 3194-3199. [Abstract] [PDF]  

Endocrinology:

Antisense Oligonucleotides Specific for Transforming Growth Factor ß2 Inhibit the Growth of Malignant Mesothelioma Both in Vitro and in Vivo

Amanda L. Marzo, David R. Fitzpatrick, Bruce W. S. Robinson, and Bernadette Scott
Cancer Res 1997 57: 3200-3207. [Abstract] [PDF]  

Experimental Therapeutics:

Mechanism of Action of E7010, an Orally Active Sulfonamide Antitumor Agent: Inhibition of Mitosis by Binding to the Colchicine Site of Tubulin

Kentaro Yoshimatsu, Atsumi Yamaguchi, Hiroshi Yoshino, Nozomu Koyanagi, and Kyosuke Kitoh
Cancer Res 1997 57: 3208-3213. [Abstract] [PDF]  

T-Cell Recognition of Tumor-associated Carbohydrates: The Nature of the Glycan Moiety Plays a Decisive Role in Determining Glycopeptide Immunogenicity

Luisa Galli-Stampino, Ernst Meinjohanns, Klaus Frische, Morten Meldal, Teis Jensen, Ole Werdelin, and S/oren Mouritsen
Cancer Res 1997 57: 3214-3222. [Abstract] [PDF]  

Immunology:

Heterogeneous Expression of Immunotherapy Candidate Proteins gp100, MART-1, and Tyrosinase in Human Melanoma Cell Lines and in Human Melanocytic Lesions

Teunis J. de Vries, Aïcha Fourkour, Theo Wobbes, Gerrit Verkroost, Dirk J. Ruiter, and Goos N. P. van Muijen
Cancer Res 1997 57: 3223-3229. [Abstract] [PDF]  

Reduced Efficacy of Allogeneic versus Syngeneic Fibroblasts Modified to Secrete Cytokines as a Tumor Vaccine Adjuvant

Atsushi Aruga, Etsuko Aruga, and Alfred E. Chang
Cancer Res 1997 57: 3230-3237. [Abstract] [PDF]  

Isolation of Novel HLA-DR Restricted Potential Tumor-associated Antigens from the Melanoma Cell Line FM3

Thomas Halder, Graham Pawelec, Alexei F. Kirkin, Jesper Zeuthen, Helmut E. Meyer, Li Kun, and Hubert Kalbacher
Cancer Res 1997 57: 3238-3244. [Abstract] [PDF]  

Germ-Line Mutations of TP53 in Li-Fraumeni Families: An Extended Study of 39 Families

Jennifer M. Varley, Gail McGown, Mary Thorncroft, Mauro F. Santibanez-Koref, Anna M. Kelsey, Karen J. Tricker, D. Gareth R. Evans, and Jillian M. Birch
Cancer Res 1997 57: 3245-3252. [Abstract] [PDF]  

Molecular Biology and Genetics:

Differential Induction of c-Jun NH₂-Terminal Kinase and c-Abl Kinase in DNA Mismatch Repair-proficient and -deficient Cells Exposed to Cisplatin

Alissar Nehmé, Rajasekaran Baskaran, Stefan Aebi, Daniel Fink, Sibylle Nebel, Bruno Cenni, Jean Y. J. Wang, Stephen B. Howell, and Randolph D. Christen
Cancer Res 1997 57: 3253-3257. [Abstract] [PDF]  

The Putative Tumor Suppressor BIN1 Is a Short-Lived Nuclear Phosphoprotein, the Localization of Which Is Altered in Malignant Cells

Robert Wechsler-Reya, Katherine Elliott, Meenhard Herlyn, and George C. Prendergast
Cancer Res 1997 57: 3258-3263. [Abstract] [PDF]  

Protective Effect of the Insulin-like Growth Factor I Receptor on Apoptosis Induced by Okadaic Acid

Consuelo D'Ambrosio, Barbara Valentinis, Marco Prisco, Krzysztof Reiss, Michele Rubini, and Renato Baserga
Cancer Res 1997 57: 3264-3271. [Abstract] [PDF]  

Prognostic Significance of HER2 and HER4 Coexpression in Childhood Medulloblastoma

Richard J. Gilbertson, Robert H. Perry, Peter J. Kelly, Andrew D. J. Pearson, and John Lunec
Cancer Res 1997 57: 3272-3280. [Abstract] [PDF]  

Cloning of P2XM, a Novel Human P2X Receptor Gene Regulated by p53

Tsutomu Urano, Hiroyuki Nishimori, Hye-jung Han, Tomohisa Furuhata, Yasutosi Kimura, Yusuke Nakamura, and Takashi Tokino
Cancer Res 1997 57: 3281-3287. [Abstract] [PDF]  

Inhibition of Nonsense-mediated Messenger RNA Decay in Clinical Samples Facilitates Detection of Human MSH2 Mutations with an in Vivo Fusion Protein Assay and Conventional Techniques

Corinne Andreutti-Zaugg, Rodney J. Scott, and Richard Iggo
Cancer Res 1997 57: 3288-3293. [Abstract] [PDF]  

Restriction Landmark Genomic Scanning (RLGS-M)-based Genome-wide Scanning of Mouse Liver Tumors for Alterations in DNA Methylation Status

Tomoya O. Akama, Yasushi Okazaki, Mitsuteru Ito, Hisato Okuizumi, Hideaki Konno, Masami Muramatsu, Christoph Plass, William A. Held, and Yoshihide Hayashizaki
Cancer Res 1997 57: 3294-3299. [Abstract] [PDF]  

Selective Inhibition of Inducible Nitric Oxide Synthase Inhibits Tumor Growth in Vivo: Studies with 1400W, a Novel Inhibitor

Lindy L. Thomsen, James M. J. Scott, Peter Topley, Richard G. Knowles, Amanda-Jane Keerie, and Anthony J. Frend
Cancer Res 1997 57: 3300-3304. [Abstract] [PDF]  

Tumor Biology:

Induction of Hepatocyte Growth Factor in Fibroblasts by Tumor-derived Factors Affects Invasive Growth of Tumor Cells: In Vitro Analysis of Tumor-Stromal Interactions

Takao Nakamura, Kunio Matsumoto, Akira Kiritoshi, Yasuo Tano, and Toshikazu Nakamura
Cancer Res 1997 57: 3305-3313. [Abstract] [PDF]  

Preclinical Evaluation of the Fluorinated 2-Nitroimidazole N-(2-hydroxy-3,3,3-trifluoropropyl)-2-(2-nitro-1-imidazolyl) Acetamide (SR-4554) as a Probe for the Measurement of Tumor Hypoxia

Eric O. Aboagye, Ross J. Maxwell, Andrew B. Kelson, Michael Tracy, Alexander D. Lewis, Martin A. Graham, Michael R. Horsman, John R. Griffiths, and Paul Workman
Cancer Res 1997 57: 3314-3318. [Abstract] [PDF]  

Correspondence re: F. Martini et al., SV40 Early Region and Large T Antigen in Human Brain Tumors, Peripheral Blood Cells, and Sperm Fluids from Healthy Individuals. Cancer Res., 56: 4820–4825, 1996

Howard Strickler
Cancer Res 1997 57: 3319-3320. [PDF]  

Letters to the Editor:

Correspondence re: F. Martini et al., SV40 Early Region and Large T Antigen in Human Brain Tumors, Peripheral Blood Cells, and Sperm Fluids from Healthy Individuals. Cancer Res., 56: 4820–4825, 1996—Reply

Mauro Tognon
Cancer Res 1997 57: 3320 [PDF]  

Articles:

Announcements

Cancer Res 1997 57: 3321-3323. [PDF]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.