Advances in Brief:

Real-Time Monitoring of Estrogen-regulated Gene Expression in Single, Living Breast Cancer Cells: A New Paradigm for the Study of Molecular Dynamics

Scott T. Willard, William J. Faught, and L. Stephen Frawley
Cancer Res 1997 57: 4447-4450. [Abstract] [PDF]  

Loss of Amino Acids ¹⁴⁹⁰Lys-Ser-Lys¹⁴⁹² in the COOH-Terminal Region of Topoisomerase II in Human Small Cell Lung Cancer Cells Selected for Resistance to Etoposide Results in an Extranuclear Enzyme Localization

Irene Wessel, Peter B. Jensen, Jacob Falck, Shelagh E. L. Mirski, Susan P. C. Cole, and Maxwell Sehested
Cancer Res 1997 57: 4451-4454. [Abstract] [PDF]  

Coding Region of NKX3.1, a Prostate-Specific Homeobox Gene on 8p21, Is Not Mutated in Human Prostate Cancers

H. James Voeller, Meena Augustus, Victor Madike, G. Steven Bova, Kenneth C. Carter, and Edward P. Gelmann
Cancer Res 1997 57: 4455-4459. [Abstract] [PDF]  

Expression of a Dominant-Negative Retinoic Acid Receptor Construct Reduces Retinoic Acid Metabolism and Retinoic Acid-Induced Inhibition of NIH-3T3 Cell Growth

Masahiro Isogai, Maria V. Chiantore, Moneera Haque, Giorgio Scita, and Luigi M. De Luca
Cancer Res 1997 57: 4460-4464. [Abstract] [PDF]  

Induction of Antitumor Cytotoxic T Lymphocytes with a MAGE-3-encoded Synthetic Peptide Presented by Human Leukocytes Antigen-A24

Fumiaki Tanaka, Tatsuo Fujie, Kouichirou Tahara, Masaki Mori, Kazutoh Takesako, Alessandro Sette, Esteban Celis, and Tsuyoshi Akiyoshi
Cancer Res 1997 57: 4465-4468. [Abstract] [PDF]  

Inactivation of H19, an Imprinted and Putative Tumor Repressor Gene, Is a Preneoplastic Event during Wilms' Tumorigenesis

Hengmi Cui, Fredrik Hedborg, Liangmei He, Agneta Nordenskjöld, Bengt Sandstedt, Susan Pfeifer-Ohlsson, and Rolf Ohlsson
Cancer Res 1997 57: 4469-4473. [Abstract] [PDF]  

p53 Does Not Repress Hypoxia-induced Transcription of the Vascular Endothelial Growth Factor Gene

Faton Agani, David G. Kirsch, Scott L. Friedman, Michael B. Kastan, and Gregg L. Semenza
Cancer Res 1997 57: 4474-4477. [Abstract] [PDF]  

Mutations in ß-Catenin Are Uncommon in Colorectal Cancer Occurring in Occasional Replication Error-positive Tumors

Maria N. Kitaeva, Liam Grogan, John P. Williams, Eileen Dimond, Kenneth Nakahara, Petr Hausner, John W. DeNobile, Peter W. Soballe, and Ilan R. Kirsch
Cancer Res 1997 57: 4478-4481. [Abstract] [PDF]  

Sustained Accumulation of the Mitotic Cyclins and Tyrosine-phosphorylated p34^cdc2 in Human G₁-S-arrested Cancer Cells but not Untransformed Cells

Thérèse David-Pfeuty and Yolande Nouvian-Dooghe
Cancer Res 1997 57: 4482-4487. [Abstract] [PDF]  

Induction of Apoptosis in Cisplatin-sensitive and -resistant Human Ovarian Cancer Cell Lines

Karen M. Henkels and John J. Turchi
Cancer Res 1997 57: 4488-4492. [Abstract] [PDF]  

GOK: A Gene at 11p15 Involved in Rhabdomyosarcoma and Rhabdoid Tumor Development

Silvia Sabbioni, Giuseppe Barbanti-Brodano, Carlo M. Croce, and Massimo Negrini
Cancer Res 1997 57: 4493-4497. [Abstract] [PDF]  

Carcinogenesis:

Ah Receptor Regulation of CYP1B1 Expression in Primary Mouse Embryo-derived Cells

David L. Alexander, Sakina E. Eltom, and Colin R. Jefcoate
Cancer Res 1997 57: 4498-4506. [Abstract] [PDF]  

The Incidence of Aberrant Crypt Foci and Colonic Carcinoma in Dimethylhydrazine-treated Rats Varies in a Site-specific Manner and Depends on Tumor Histology

Hyun-Sook Park, Robert A. Goodlad, and Nicholas A. Wright
Cancer Res 1997 57: 4507-4510. [Abstract] [PDF]  

Endocrinology:

Regulation of Androgen-dependent Prostatic Cancer Cell Growth: Androgen Regulation of CDK2, CDK4, and CKI p16 Genes

Shan Lu, Sophia Y. Tsai, and Ming-Jer Tsai
Cancer Res 1997 57: 4511-4516. [Abstract] [PDF]  

Induction of Parathyroid Hormone-related Peptide by the Ras Oncogene: Role of Ras Farnesylation Inhibitors as Potential Therapeutic Agents for Hypercalcemia of Malignancy

Fasika Aklilu, Morag Park, David Goltzman, and Shafaat Ahmed Rabbani
Cancer Res 1997 57: 4517-4522. [Abstract] [PDF]  

Epidemiology and Prevention:

Microsatellite Instability in Gastric Cancer Is Associated with Tumor Location and Family History in a High-Risk Population from Tuscany

Laura Ottini, Domenico Palli, Mario Falchetti, Cristina D'Amico, Andrea Amorosi, Calogero Saieva, Anna Calzolari, Federica Cimoli, Caterina Tatarelli, Laura De Marchis, Giovanna Masala, Renato Mariani-Costantini, and Alessandro Cama
Cancer Res 1997 57: 4523-4529. [Abstract] [PDF]  

Experimental Therapeutics:

Antitumor Activity of Carcinoma-reactive BR96-Doxorubicin Conjugate against Human Carcinomas in Athymic Mice and Rats and Syngeneic Rat Carcinomas in Immunocompetent Rats

Hans Olov Sjögren, M. Isaksson, David Willner, Ingegerd Hellström, Karl Erik Hellström, and Pamela A. Trail
Cancer Res 1997 57: 4530-4536. [Abstract] [PDF]  

Tumor-targeted Salmonella as a Novel Anticancer Vector

John M. Pawelek, K. Brooks Low, and David Bermudes
Cancer Res 1997 57: 4537-4544. [Abstract] [PDF]  

19-nor-Hexafluoride Analogue of Vitamin D₃: A Novel Class of Potent Inhibitors of Proliferation of Human Breast Cell Lines

Michiaki Koike, Elena Elstner, Moray J. Campbell, Hiroya Asou, Milan Uskokovic, Nobuyoshi Tsuruoka, and H. Phillip Koeffler
Cancer Res 1997 57: 4545-4550. [Abstract] [PDF]  

Photodynamic Therapy Using a Protoporphyrinogen Oxidase Inhibitor

Victor H. Fingar, T. Jeffery Wieman, Kimberly S. McMahon, Pamela S. Haydon, Blaik P. Halling, Debra A. Yuhas, and James W. Winkelman
Cancer Res 1997 57: 4551-4556. [Abstract] [PDF]  

Interleukin 18 Induces the Sequential Activation of Natural Killer Cells and Cytotoxic T Lymphocytes to Protect Syngeneic Mice from Transplantation with Meth A Sarcoma

Mark J. Micallef, Tadao Tanimoto, Keizo Kohno, Masao Ikeda, and Masashi Kurimoto
Cancer Res 1997 57: 4557-4563. [Abstract] [PDF]  

Aclacinomycin A Stabilizes Topoisomerase I Covalent Complexes

John L. Nitiss, Philippe Pourquier, and Yves Pommier
Cancer Res 1997 57: 4564-4569. [Abstract] [PDF]  

Immunology:

Identification of an Enhancer Agonist Cytotoxic T Lymphocyte Peptide from Human Carcinoembryonic Antigen

Sam Zaremba, Elena Barzaga, Mingzhu Zhu, Nirmolini Soares, Kwong-Yok Tsang, and Jeffrey Schlom
Cancer Res 1997 57: 4570-4577. [Abstract] [PDF]  

Molecular Biology and Genetics:

High Levels of Expression and Nuclear Localization of Interleukin-1 ß Converting Enzyme (ICE) and CPP32 in Favorable Human Neuroblastomas

Akira Nakagawara, Yohko Nakamura, Hitoshi Ikeda, Takaki Hiwasa, Keisuke Kuida, Michael S-S. Su, Huaqing Zhao, Avital Cnaan, and Shigeru Sakiyama
Cancer Res 1997 57: 4578-4584. [Abstract] [PDF]  

Previously Hidden Chromosome Aberrations in T(12;15)-positive BALB/c Plasmacytomas Uncovered by Multicolor Spectral Karyotyping

Allen E. Coleman, Evelin Schröck, Zoë Weaver, Stan du Manoir, Fangteng Yang, Malcolm A. Ferguson-Smith, Thomas Ried, and Siegfried Janz
Cancer Res 1997 57: 4585-4592. [Abstract] [PDF]  

Humanization of an Anti-Vascular Endothelial Growth Factor Monoclonal Antibody for the Therapy of Solid Tumors and Other Disorders

Leonard G. Presta, Helen Chen, Shane J. O'Connor, Vanessa Chisholm, Y. Gloria Meng, Lynne Krummen, Marjorie Winkler, and Napoleone Ferrara
Cancer Res 1997 57: 4593-4599. [Abstract] [PDF]  

A DNA Double-Strand Break Defective Fibroblast Cell Line (180BR) Derived from a Radiosensitive Patient Represents a New Mutant Phenotype

Christophe Badie, Michele Goodhardt, Alastair Waugh, Noëlle Doyen, Nicolas Foray, Patrick Calsou, Belinda Singleton, David Gell, Bernard Salles, Penny Jeggo, Colin F. Arlett, and Edmond-Philippe Malaise
Cancer Res 1997 57: 4600-4607. [Abstract] [PDF]  

Alterations of the Cyclin D1/p16-pRB Pathway in Mantle Cell Lymphoma

Martin H. Dreyling, Lars Bullinger, German Ott, Stephan Stilgenbauer, Hans K. Müller-Hermelink, Martin Bentz, Wolfgang Hiddemann, and Hartmut Döhner
Cancer Res 1997 57: 4608-4614. [Abstract] [PDF]  

Genomic Imprinting and Igf2 Influence Liver Tumorigenesis and Loss of Heterozygosity in SV40 T Antigen Transgenic Mice

Ramsi Haddad and William A. Held
Cancer Res 1997 57: 4615-4623. [Abstract] [PDF]  

Loss of ß-Catenin Regulation by the APC Tumor Suppressor Protein Correlates with Loss of Structure Due to Common Somatic Mutations of the Gene

Bonnee Rubinfeld, Iris Albert, Emilio Porfiri, Susan Munemitsu, and Paul Polakis
Cancer Res 1997 57: 4624-4630. [Abstract] [PDF]  

Re-expression of elafin in 21MT2 Breast Carcinomas by Phorbol 12-Myristate 13-Acetate Is Mediated by the Ap1 Site in the elafin Promoter

Ming Zhang, David Magit, Arthur B. Pardee, and Ruth Sager
Cancer Res 1997 57: 4631-4636. [Abstract] [PDF]  

Hypermutability of UV-treated Plasmids in Dysplastic Nevus/Familial Melanoma Cell Lines

Shin-Ichi Moriwaki, Robert E. Tarone, Margaret A. Tucker, Alisa M. Goldstein, and Kenneth H. Kraemer
Cancer Res 1997 57: 4637-4641. [Abstract] [PDF]  

Tumor Biology:

Human Breast Cancer Cells and Normal Mammary Epithelial Cells: Retinol Metabolism and Growth Inhibition by the Retinol Metabolite 4-Oxoretinol

Anne C. Chen, Xiaojia Guo, Fadila Derguini, and Lorraine J. Gudas
Cancer Res 1997 57: 4642-4651. [Abstract] [PDF]  

Induction of Retinoid Resistance in Breast Cancer Cells by Overexpression of cJun

LiMin Yang, HeeTae Kim, Deborah Munoz-Medellin, Praveen Reddy, and Powel H. Brown
Cancer Res 1997 57: 4652-4661. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1997 57: 4662-4664. [PDF]  

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