Advances in Brief:

Carcinoma-associated Expression of Core 2 ß-1,6-N-Acetylglucosaminyltransferase Gene in Human Colorectal Cancer: Role of O-Glycans in Tumor Progression

Kazuhisa Shimodaira, Jun Nakayama, Naoshi Nakamura, Osamu Hasebe, Tsutomu Katsuyama, and Minoru Fukuda
Cancer Res 1997 57: 5201-5206. [Abstract] [PDF]  

Absence of Fhit Protein in Primary Lung Tumors and Cell Lines with FHIT Gene Abnormalities

Gabriella Sozzi, Silvana Tornielli, Elda Tagliabue, Laura Sard, Francesco Pezzella, Ugo Pastorino, Fabiola Minoletti, Silvana Pilotti, Cathy Ratcliffe, Maria Luisa Veronese, Peter Goldstraw, Kay Huebner, Carlo M. Croce, and Marco A. Pierotti
Cancer Res 1997 57: 5207-5212. [Abstract] [PDF]  

Patterns of Chromosomal Alterations in Metastasizing and Nonmetastasizing Primary Head and Neck Carcinomas

Ulrike Bockmühl, Simone Petersen, Sven Schmidt, Günter Wolf, Volker Jahnke, Manfred Dietel, and Iver Petersen
Cancer Res 1997 57: 5213-5216. [Abstract] [PDF]  

Intracellular Localization of p53 Tumor Suppressor Protein in -irradiated Cells Is Cell Cycle Regulated and Determined by the Nucleus

Elena A. Komarova, Carolyn R. Zelnick, Dot Chin, Marija Zeremski, Anatoly S. Gleiberman, Sarah S. Bacus, and Andrei V. Gudkov
Cancer Res 1997 57: 5217-5220. [Abstract] [PDF]  

MMAC1/PTEN Mutations in Primary Tumor Specimens and Tumor Cell Lines

David H-F. Teng, Rong Hu, Huai Lin, Thaylon Davis, Diana Iliev, Cheryl Frye, Brad Swedlund, Kipp L. Hansen, Vickie L. Vinson, Kathryn L. Gumpper, Lee Ellis, Adel El-Naggar, Marsha Frazier, Samar Jasser, Lauren A. Langford, Jeff Lee, Gordon B. Mills, Mark A. Pershouse, Raphael E. Pollack, Carmen Tornos, Patricia Troncoso, W. K. Alfred Yung, Gregory Fujii, Amy Berson, Robert Bookstein, Joseph B. Bolen, Sean V. Tavtigian, and Peter A. Steck
Cancer Res 1997 57: 5221-5225. [Abstract] [PDF]  

Expression of PACE4 in Chemically Induced Carcinomas Is Associated with Spindle Cell Tumor Conversion and Increased Invasive Ability

Frank C. Hubbard, Tamra L. Goodrow, Shao-Chen Liu, Murray H. Brilliant, Paul Basset, Richard E. Mains, and Andres J. P. Klein-Szanto
Cancer Res 1997 57: 5226-5231. [Abstract] [PDF]  

Evidence That the Multidrug Resistance Protein (MRP) Functions as a Co-Transporter of Glutathione and Natural Product Toxins

Germana Rappa, Aurelio Lorico, Richard A. Flavell, and Alan C. Sartorelli
Cancer Res 1997 57: 5232-5237. [Abstract] [PDF]  

Disruption of the Murine MRP (Multidrug Resistance Protein) Gene Leads to Increased Sensitivity to Etoposide (VP-16) and Increased Levels of Glutathione

Aurelio Lorico, Germana Rappa, Rick A. Finch, Di Yang, Richard A. Flavell, and Alan C. Sartorelli
Cancer Res 1997 57: 5238-5242. [Abstract] [PDF]  

NADH Dehydrogenase Deficiency in an Apoptosis-resistant Mutant Isolated from a Human HL-60 Leukemia Cell Line

Akihiro Kataoka, Masaru Kubota, Ken-ichiro Watanabe, Machiko Sawada, Seiji Koishi, Ying Wei Lin, Ikuya Usami, Yuichi Akiyama, Toshiyuki Kitoh, and Kenshi Furusho
Cancer Res 1997 57: 5243-5245. [Abstract] [PDF]  

Liposomal Doxorubicin Circumvents PSC 833-Free Drug Interactions, Resulting in Effective Therapy of Multidrug-resistant Solid Tumors

Rajesh Krishna and Lawrence D. Mayer
Cancer Res 1997 57: 5246-5253. [Abstract] [PDF]  

PTEN/MMAC1 Mutations and EGFR Amplification in Glioblastomas

Wanguo Liu, C. David James, Lori Frederick, Benjamin E. Alderete, and Robert B. Jenkins
Cancer Res 1997 57: 5254-5257. [Abstract] [PDF]  

The Use of Exfoliative Cell Samples to Map Clonal Genetic Alterations in the Oral Epithelium of High-Risk Patients

Miriam P. Rosin, Joel B. Epstein, Ken Berean, Scott Durham, John Hay, Xing Cheng, Tao Zeng, Yongqian Huang, and Lewei Zhang
Cancer Res 1997 57: 5258-5260. [Abstract] [PDF]  

Human Tumor Blood Flow Is Enhanced by Nicotinamide and Carbogen Breathing

Melanie E. B. Powell, Sally A. Hill, Michele I. Saunders, Peter J. Hoskin, and David J. Chaplin
Cancer Res 1997 57: 5261-5264. [Abstract] [PDF]  

Overexpression of Manganese Superoxide Dismutase Selectively Modulates the Activity of Jun-associated Transcription Factors in Fibrosarcoma Cells

Kelley K. Kiningham and Daret K. St. Clair
Cancer Res 1997 57: 5265-5271. [Abstract] [PDF]  

Galectin-3: A Novel Antiapoptotic Molecule with A Functional BH1 (NWGR) Domain of Bcl-2 Family

Shiro Akahani, Pratima Nangia-Makker, Hidenori Inohara, Hyeong-Reh Choi Kim, and Avraham Raz
Cancer Res 1997 57: 5272-5276. [Abstract] [PDF]  

Human Angiostatin Inhibits Murine Hemangioendothelioma Tumor Growth in Vivo

Brian J. Lannutti, Stephen T. Gately, M. Eugenia Quevedo, Gerald A. Soff, and Amy S. Paller
Cancer Res 1997 57: 5277-5280. [Abstract] [PDF]  

Vascular Endothelial Growth Factor Is a Predictor of Relapse and Stage Progression in Superficial Bladder Cancer

Jeremy P. Crew, Tim O'Brien, Mike Bradburn, Sue Fuggle, Roy Bicknell, David Cranston, and Adrian L. Harris
Cancer Res 1997 57: 5281-5285. [Abstract] [PDF]  

Experimental Therapeutics:

Murine Susceptibility to Radiation-induced Pulmonary Fibrosis Is Influenced by a Genetic Factor Implicated in Susceptibility to Bleomycin-induced Pulmonary Fibrosis

Christina K. Haston and Elizabeth L. Travis
Cancer Res 1997 57: 5286-5291. [Abstract] [PDF]  

Transient Induction of the MRP/GS-X Pump and -Glutamylcysteine Synthetase by 1-(4-Amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea in Human Glioma Cells

Akira Gomi, Souji Shinoda, Toshio Masuzawa, Toshihisa Ishikawa, and M. Tien Kuo
Cancer Res 1997 57: 5292-5299. [Abstract] [PDF]  

The Protein Kinase C Activators Phorbol Esters and Phosphatidylserine Inhibit Neutral Sphingomyelinase Activation, Ceramide Generation, and Apoptosis Triggered by Daunorubicin

Véronique Mansat, Guy Laurent, Thierry Levade, Ali Bettaïeb, and Jean-Pierre Jaffrézou
Cancer Res 1997 57: 5300-5304. [Abstract] [PDF]  

Intravenous Administration of Irinotecan Elevates the Blood ß-Glucuronidase Activity in Rats

Norimasa Kaneda, Akinobu Kurita, Yukiko Hosokawa, Teruo Yokokura, and Shoji Awazu
Cancer Res 1997 57: 5305-5308. [Abstract] [PDF]  

Improved Treatment of Medullary Thyroid Cancer in a Nude Mouse Model by Combined Radioimmunochemotherapy: Doxorubicin Potentiates the Therapeutic Efficacy of Radiolabeled Antibodies in a Radioresistant Tumor Type

Thomas M. Behr, Erik Wulst, Sven Radetzky, Rosalyn D. Blumenthal, Robert M. Dunn, Stefan Gratz, Margret Rave-Fränk, Heinz Schmidberger, Friedhelm Raue, and Wolfgang Becker
Cancer Res 1997 57: 5309-5319. [Abstract] [PDF]  

Immunology:

T-cell Receptor Repertoire in Matched MART-1 Peptide-stimulated Peripheral Blood Lymphocytes and Tumor-infiltrating Lymphocytes

David J. Cole, Michael C. Wilson, Licia Rivoltini, Mary Custer, and Michael I. Nishimura
Cancer Res 1997 57: 5320-5327. [Abstract] [PDF]  

Molecular Biology and Genetics:

V-SRC Induces Expression of Hypoxia-inducible Factor 1 (HIF-1) and Transcription of Genes Encoding Vascular Endothelial Growth Factor and Enolase 1: Involvement of HIF-1 in Tumor Progression

Bing-Hua Jiang, Faton Agani, Antonino Passaniti, and Gregg L. Semenza
Cancer Res 1997 57: 5328-5335. [Abstract] [PDF]  

Low Frequency of p16/CDKN2A Methylation in Sporadic Melanoma: Comparative Approaches for Methylation Analysis of Primary Tumors

Mark L. Gonzalgo, Christina M. Bender, Edward H. You, J. Michael Glendening, José F. Flores, Graeme J. Walker, Nicholas K. Hayward, Peter A. Jones, and Jane W. Fountain
Cancer Res 1997 57: 5336-5347. [Abstract] [PDF]  

Enforced Expression of the M_r 33,000 Pim-1 Kinase Enhances Factor-independent Survival and Inhibits Apoptosis in Murine Myeloid Cells

Michael Lilly and Andrew Kraft
Cancer Res 1997 57: 5348-5355. [Abstract] [PDF]  

Genomic Organization and Mutation Analysis of Hel-N1 in Lung Cancers with Chromosome 9p21 Deletions

Paul Cairns, Kenji Okami, Peter King, Julia Bonacum, Steve Ahrendt, Li Wu, Li Mao, Jin Jen, and David Sidransky
Cancer Res 1997 57: 5356-5359. [Abstract] [PDF]  

Tumor Biology:

Role of O⁶-Methylguanine-DNA Methyltransferase in the Resistance of Pancreatic Tumors to DNA Alkylating Agents

Demetrius M. Kokkinakis, Mansoor M. Ahmed, Ruby Delgado, Mushdaq M. Fruitwala, Mohammed Mohiuddin, and Jorge Albores-Saavedra
Cancer Res 1997 57: 5360-5368. [Abstract] [PDF]  

Fibroblast Growth Factor Receptor 2 Limits and Receptor 1 Accelerates Tumorigenicity of Prostate Epithelial Cells

Shuju Feng, Fen Wang, Akio Matsubara, Mikio Kan, and Wallace L. McKeehan
Cancer Res 1997 57: 5369-5378. [Abstract] [PDF]  

Molecular Evidence That Most but not All Carcinosarcomas of the Uterus Are Combination Tumors

Hiroko Wada, Takayuki Enomoto, Masami Fujita, Kiyoshi Yoshino, Ryuichi Nakashima, Hirohisa Kurachi, Tomoko Haba, Kenichi Wakasa, Kenneth R. Shroyer, Masahiko Tsujimoto, Tadashi Hongyo, Taisei Nomura, and Yuji Murata
Cancer Res 1997 57: 5379-5385. [Abstract] [PDF]  

The Osteoclast-associated Protease Cathepsin K Is Expressed in Human Breast Carcinoma

Amanda J. Littlewood-Evans, Graeme Bilbe, Wayne B. Bowler, David Farley, Brenda Wlodarski, Toshio Kokubo, Tetsuya Inaoka, John Sloane, Dean B. Evans, and James A. Gallagher
Cancer Res 1997 57: 5386-5390. [Abstract] [PDF]  

Met and Hepatocyte Growth Factor/Scatter Factor Expression in Human Gliomas

Shahriar Koochekpour, Michael Jeffers, Shen Rulong, Gregory Taylor, Eric Klineberg, Eric A. Hudson, James H. Resau, and George F. Vande Woude
Cancer Res 1997 57: 5391-5398. [Abstract] [PDF]  

Expression of Multiple Endocrine Neoplasia 2B RET in Neuroblastoma Cells Alters Cell Adhesion in Vitro, Enhances Metastatic Behavior in Vivo, and Activates Jun Kinase

Glenn M. Marshall, Anne E. Peaston, Jayne E. Hocker, Stewart A. Smith, Loen M. Hansford, Vivienne Tobias, Murray D. Norris, Michelle Haber, Darrin P. Smith, Maria J. Lorenzo, Bruce A. J. Ponder, and John F. Hancock
Cancer Res 1997 57: 5399-5405. [Abstract] [PDF]  

Methyl-p-hydroxyphenyllactate-esterase Activity in Breast Cancer: A Potentially New Prognostic Factor in Short-Term Follow-up

Arnaldo Carbone, Fabio Giosuè Serra, Gabriella Ferrandina, Giovanni Scambia, Daniela Terribile, Rocco Bellantone, Mauro Piantelli, and Franco Oreste Ranelletti
Cancer Res 1997 57: 5406-5409. [Abstract] [PDF]  

Epidermal Growth Factor Regulates Protein Kinase A Activity in Murine Fibrosarcoma Cells: Differences between Metastatic and Nonmetastatic Tumor Cell Variants

Daniel Fishman, Lubov Galitzki, Esther Priel, and Shraga Segal
Cancer Res 1997 57: 5410-5415. [Abstract] [PDF]  

Fibronectin Secretion from Human Peritoneal Tissue Induces M_r 92,000 Type IV Collagenase Expression and Invasion in Ovarian Cancer Cell Lines

Kiyosumi Shibata, Fumitaka Kikkawa, Akihiro Nawa, Nobuhiko Suganuma, and Michinari Hamaguchi
Cancer Res 1997 57: 5416-5420. [Abstract] [PDF]  

Vascular Endothelial Growth Factor Up-Regulates Its Receptor fms-like Tyrosine Kinase 1 (FLT-1) and a Soluble Variant of FLT-1 in Human Vascular Endothelial Cells

Bernhard Barleon, Gerhard Siemeister, Georg Martiny-Baron, Karin Weindel, Christel Herzog, and Dieter Marmé
Cancer Res 1997 57: 5421-5425. [Abstract] [PDF]  

Posttranscriptional Regulation of Protein Expression in Human Epithelial Carcinoma Cells by Adenine-Uridine-Rich Elements in the 3'-Untranslated Region of Tumor Necrosis Factor- Messenger RNA

Enhong Wang, Wei-Jun Ma, Carol Aghajanian, and David R. Spriggs
Cancer Res 1997 57: 5426-5433. [Abstract] [PDF]  

Letters to the Editor:

Correspondence re: J. S. DeFrank et al., p53-null Cells Are More Sensitive to Ultraviolet Light Only in the Presence of Caffeine. Cancer Res., 56: 5365–5368, 1996: Letter

Martin L. Smith and Albert J. Fornace, Jr.
Cancer Res 1997 57: 5434-5435. [PDF]  

Correspondence re: J. S. DeFrank et al., p53-null Cells Are More Sensitive to Ultraviolet Light Only in the Presence of Caffeine. Cancer Res., 56: 5365–5368, 1996—Reply

Simon Powell and Jeffrey DeFrank
Cancer Res 1997 57: 5435-5436. [PDF]  

Articles:

Announcements

Cancer Res 1997 57: 5437-5439. [PDF]  

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