Advances in Brief:

Promoting Apoptosis: A Novel Activity Associated with the Cyclin-dependent Kinase Inhibitor p27

Yu Katayose, Min Kim, Amol N. S. Rakkar, Zhuangwu Li, Kenneth H. Cowan, and Prem Seth
Cancer Res 1997 57: 5441-5445. [Abstract] [PDF]  

Mutations of the MEN1 Tumor Suppressor Gene in Pituitary Tumors

Zhengping Zhuang, Shereen Z. Ezzat, Alexander O. Vortmeyer, Robert Weil, Edward H. Oldfield, Won-Sang Park, Svetlana Pack, Steve Huang, Sunita K. Agarwal, Siradanahalli C. Guru, Pachiappan Manickam, Larisa V. Debelenko, Mary Beth Kester, Shodimu-Emmanuel Olufemi, Christina Heppner, Judy S. Crabtree, A. Lee Burns, Allen M. Spiegel, Stephen J. Marx, Settara C. Chandrasekharappa, Francis S. Collins, Michael R. Emmert-Buck, Lance A. Liotta, Sylvia L. Asa, and Irina A. Lubensky
Cancer Res 1997 57: 5446-5451. [Abstract] [PDF]  

TCL1 Is Overexpressed in Patients Affected by Adult T-Cell Leukemias

Maria Grazia Narducci, Antonella Stoppacciaro, Kazunori Imada, Takashi Uchiyama, Laura Virgilio, Cristina Lazzeri, Carlo Maria Croce, and Giandomenico Russo
Cancer Res 1997 57: 5452-5456. [Abstract] [PDF]  

The DNA Repair Activity of Human Redox/Repair Protein APE/Ref-1 Is Inactivated by Phosphorylation

Adly Yacoub, Mark R. Kelley, and Walter A. Deutsch
Cancer Res 1997 57: 5457-5459. [Abstract] [PDF]  

The 95-Kilodalton Membrane Glycoprotein Overexpressed in Novel Multidrugresistant Breast Cancer Cells Is NCA, the Nonspecific Cross-reacting Antigen of Carcinoembryonic Antigen

Douglas D. Ross, Yongming Gao, Weidong Yang, John Leszyk, John Shively, and L. Austin Doyle
Cancer Res 1997 57: 5460-5464. [Abstract] [PDF]  

Overexpression of Phospholipase C-1 in Rat 3Y1 Fibroblast Cells Leads to Malignant Transformation

Jong-Soo Chang, Dong Young Noh, In Ae Park, Myung Jong Kim, Hebok Song, Sung Ho Ryu, and Pann-Ghill Suh
Cancer Res 1997 57: 5465-5468. [Abstract] [PDF]  

Genome-wide Search for Loss of Heterozygosity Shows Extensive Genetic Diversity of Human Breast Carcinomas

Fabienne Kerangueven, Tetsuro Noguchi, François Coulier, Florence Allione, Véronique Wargniez, Joelle Simony-Lafontaine, Michel Longy, Jocelyne Jacquemier, Hagay Sobol, François Eisinger, and Daniel Birnbaum
Cancer Res 1997 57: 5469-5474. [Abstract] [PDF]  

A Canalicular Multispecific Organic Anion Transporter (cMOAT) Antisense cDNA Enhances Drug Sensitivity in Human Hepatic Cancer Cells

Koji Koike, Takeshi Kawabe, Toshiya Tanaka, Satoshi Toh, Takeshi Uchiumi, Morimasa Wada, Shin-ichi Akiyama, Mayumi Ono, and Michihiko Kuwano
Cancer Res 1997 57: 5475-5479. [Abstract] [PDF]  

The I1307K APC Mutation Does Not Predispose to Colorectal Cancer in Jewish Ashkenazi Breast and Breast-Ovarian Cancer Kindreds

Luba Petrukhin, JoEllen Dangel, Lisa Vanderveer, Josephine Costalas, Alfonso Bellacosa, Generosa Grana, Mary Daly, and Andrew K. Godwin
Cancer Res 1997 57: 5480-5484. [Abstract] [PDF]  

Nuclear Location and Cell Cycle Regulation of the BRCA2 Protein

David Bertwistle, Sally Swift, Nicola J. Marston, Laura E. Jackson, Susan Crossland, Mark R. Crompton, Christopher J. Marshall, and Alan Ashworth
Cancer Res 1997 57: 5485-5488. [Abstract] [PDF]  

Chemoprevention of Pulmonary Carcinogenesis by Aerosolized Budesonide in Female A/J Mice

Lee W. Wattenberg, Timothy S. Wiedmann, Richard D. Estensen, Cheryl L. Zimmerman, Vernon E. Steele, and Gary J. Kelloff
Cancer Res 1997 57: 5489-5492. [Abstract] [PDF]  

An Association between the Allele Coding for a Low Activity Variant of Catechol-O-methyltransferase and the Risk for Breast Cancer

Jackie A. Lavigne, Kathy J. Helzlsouer, Han-Yao Huang, Paul T. Strickland, Douglas A. Bell, Ornella Selmin, Mary A. Watson, Sandra Hoffman, George W. Comstock, and James D. Yager
Cancer Res 1997 57: 5493-5497. [Abstract] [PDF]  

eps15 and eps15R Are Essential Components of the Endocytic Pathway

Roberta Carbone, Silvia Fré, Gioacchin Iannolo, Francesca Belleudi, Patrizia Mancini, Pier Giuseppe Pelicci, Maria Rosaria Torrisi, and Pier Paolo Di Fiore
Cancer Res 1997 57: 5498-5504. [Abstract] [PDF]  

Clinical Investigations:

Mitosin (a New Proliferation Marker) Correlates with Clinical Outcome in Node-negative Breast Cancer

Gary M. Clark, D. Craig Allred, Susan G. Hilsenbeck, Gary C. Chamness, C. Kent Osborne, Diane Jones, and Wen-Hwa Lee
Cancer Res 1997 57: 5505-5508. [Abstract] [PDF]  

Age-dependent Tetrahydrothiophenium Ion Formation in Young Children and Adults Receiving High-Dose Busulfan

John P. Gibbs, Georgia Murray, Linda Risler, Jenny Y. Chien, Raj Dev, and John T. Slattery
Cancer Res 1997 57: 5509-5516. [Abstract] [PDF]  

Aggressive Breast Cancer Leads to Discrepant Serum Levels of the Type I Procollagen Propeptides PINP and PICP

Arja Jukkola, Riitta Tähtelä, Eric Thölix, Klaus Vuorinen, Guillermo Blanco, Leila Risteli, and Juha Risteli
Cancer Res 1997 57: 5517-5520. [Abstract] [PDF]  

Experimental Therapeutics:

Effects of Novel Spermine Analogues on Cell Cycle Progression and Apoptosis in MALME-3M Human Melanoma Cells

Debora L. Kramer, Mirjana Fogel-Petrovic, Paula Diegelman, Jeanine M. Cooley, Ralph J. Bernacki, Jim S. McManis, Raymond J. Bergeron, and Carl W. Porter
Cancer Res 1997 57: 5521-5527. [Abstract] [PDF]  

Multicell Spheroid Response to Drugs Predicted with the Comet Assay

Peggy L. Olive and Judit P. Banáth
Cancer Res 1997 57: 5528-5533. [Abstract] [PDF]  

Immunology:

Autologous Dendritic Cells Derived from CD34⁺ Progenitors and from Monocytes Are Not Functionally Equivalent Antigen-presenting Cells in the Induction of Melan-A/Mart-1_27–35-specific CTLs from Peripheral Blood Lymphocytes of Melanoma Patients with Low Frequency of CTL Precursors

Roberta Mortarini, Andrea Anichini, Massimo Di Nicola, Salvatore Siena, Marco Bregni, Filiberto Belli, Alessandra Molla, Alessandro M. Gianni, and Giorgio Parmiani
Cancer Res 1997 57: 5534-5541. [Abstract] [PDF]  

Molecular Biology and Genetics:

A Transgenic Mouse Model with Cyclin D1 Overexpression Results in Cell Cycle, Epidermal Growth Factor Receptor, and p53 Abnormalities

Annegret Mueller, Robert Odze, Timothy D. Jenkins, Ali Shahsesfaei, Hiroshi Nakagawa, Takuya Inomoto, and Anil K. Rustgi
Cancer Res 1997 57: 5542-5549. [Abstract] [PDF]  

Adenovirus-mediated Manganese Superoxide Dismutase Gene Transfer to Hamster Cheek Pouch Carcinoma Cells

Ernest W. N. Lam, Ralf Zwacka, John F. Engelhardt, Beverly L. Davidson, Frederick E. Domann, Jr., Tao Yan, and Larry W. Oberley
Cancer Res 1997 57: 5550-5556. [Abstract] [PDF]  

Chromosomal Instability and Its Relationship to Other End Points of Genomic Instability

Charles L. Limoli, Mark I. Kaplan, James Corcoran, Mark Meyers, David A. Boothman, and William F. Morgan
Cancer Res 1997 57: 5557-5563. [Abstract] [PDF]  

Tumor Biology:

Transgenic Mice Overexpressing a Dominant-negative Mutant Type II Transforming Growth Factor ß Receptor Show Enhanced Tumorigenesis in the Mammary Gland and Lung in Response to the Carcinogen 7,12-Dimethylbenz-[a]-anthracene

Erwin P. Böttinger, John L. Jakubczak, Diana C. Haines, Kerri Bagnall, and Lalage M. Wakefield
Cancer Res 1997 57: 5564-5570. [Abstract] [PDF]  

Fas/APO-1 (CD95) Is Not Translocated to the Cell Membrane in Esophageal Adenocarcinoma

Steven J. Hughes, Yoshihiro Nambu, Oliver S. Soldes, Daniel Hamstra, Alnawaz Rehemtulla, Mark D. Iannettoni, Mark B. Orringer, and David G. Beer
Cancer Res 1997 57: 5571-5578. [Abstract] [PDF]  

Expression of Sex Hormone-binding Globulin Exon VII Splicing Variant Messenger RNA in Human Uterine Endometrial Cancers

Ryou Misao, Yoshihito Nakanishi, Jiro Fujimoto, and Teruhiko Tamaya
Cancer Res 1997 57: 5579-5583. [Abstract] [PDF]  

Abrogation of Wild-type p53-mediated Transactivation is Insufficient for Mutant p53-induced Immortalization of Normal Human Mammary Epithelial Cells

Yu-an Cao, Qingshen Gao, David E. Wazer, and Vimla Band
Cancer Res 1997 57: 5584-5589. [Abstract] [PDF]  

Angiogenesis by Fibroblast Growth Factor 4 Is Mediated through an Autocrine Up-Regulation of Vascular Endothelial Growth Factor Expression

Christophe F. Deroanne, Amin Hajitou, Claire-M. Calberg-Bacq, Betty V. Nusgens, and Charles M. Lapière
Cancer Res 1997 57: 5590-5597. [Abstract] [PDF]  

Cell Scattering and Migration Induced by Autocrine Transforming Growth Factor in Human Glioma Cells in Vitro

A. El-Obeid, E. Bongcam-Rudloff, M. Sörby, A. Östman, M. Nistér, and B. Westermark
Cancer Res 1997 57: 5598-5604. [Abstract] [PDF]  

Telomerase Activity in the Normal and Neoplastic Rat Mammary Gland

Debora Varon, Cheng Jiang, Catigan Hedican, Jeffrey S. Dome, Christopher B. Umbricht, Lisa A. Carey, Henry J. Thompson, and Saraswati Sukumar
Cancer Res 1997 57: 5605-5609. [Abstract] [PDF]  

Letters to the Editor:

Correspondence re: G. Palumbo et al., The tyrphostin AG17 induces apoptosis and inhibition of cdk2 activity in a lymphoma cell line that overexpresses bcl-2. Cancer Res., 57: 2434–2439, 1997: Letter

Edward A. Sausville
Cancer Res 1997 57: 5610 [PDF]  

Correspondence re: G. Palumbo et al., The tyrphostin AG17 induces apoptosis and inhibition of cdk2 activity in a lymphoma cell line that overexpresses bcl-2. Cancer Res., 57: 2434–2439, 1997—Reply

Alexander Levitzki and Dina Ben-Yehuda
Cancer Res 1997 57: 5610 [PDF]  

Articles:

Announcements

Cancer Res 1997 57: 5611-5613. [PDF]  

Errata

Cancer Res 1997 57: 5613 [PDF]  

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