Advances in Brief:

A Phosphatidylinositol 3-Kinase Inhibitor Induces a Senescent-like Growth Arrest in Human Diploid Fibroblasts

Maria Tresini, Madhumalti Mawal-Dewan, Vincent J. Cristofalo, and Christian Sell
Cancer Res 1998 58: 1-4. [Abstract] [PDF]  

Etiological Involvement of Oncogenic Human Papillomavirus in Tonsillar Squamous Cell Carcinomas Lacking Retinoblastoma Cell Cycle Control

Thomas Andl, Tomas Kahn, Andreas Pfuhl, Teodora Nicola, Ralf Erber, Christian Conradt, Wolfgang Klein, Matthias Helbig, Andreas Dietz, Hagen Weidauer, and Franz X. Bosch
Cancer Res 1998 58: 5-12. [Abstract] [PDF]  

High-Efficiency Gene Transfer and Selection of Human Hematopoietic Progenitor Cells with a Hybrid EBV/Retroviral Vector Expressing the Green Fluorescence Protein

Francesco Grignani, Todd Kinsella, Amedea Mencarelli, Mauro Valtieri, Daniela Riganelli, Fausto Grignani, Luisa Lanfrancone, Cesare Peschle, Garry P. Nolan, and Pier Giuseppe Pelicci
Cancer Res 1998 58: 14-19. [Abstract] [PDF]  

Overexpression of a Rabbit Liver Carboxylesterase Sensitizes Human Tumor Cells to CPT-11

Mary K. Danks, Christopher L. Morton, Cynthia A. Pawlik, and Philip M. Potter
Cancer Res 1998 58: 20-22. [Abstract] [PDF]  

Precise Microdissection of Human Prostate Cancers Reveals Genotypic Heterogeneity

Catherine A. Macintosh, Michael Stower, Nick Reid, and Norman J. Maitland
Cancer Res 1998 58: 23-28. [Abstract] [PDF]  

Mutation of the PTEN (MMAC1) Tumor Suppressor Gene in a Subset of Glioblastomas but not in Meningiomas with Loss of Chromosome Arm 10q

Jan Boström, J. M. J. Ludwig Cobbers, Marietta Wolter, Ghazaleh Tabatabai, Ruthild G. Weber, Peter Lichter, V. Peter Collins, and Guido Reifenberger
Cancer Res 1998 58: 29-33. [Abstract] [PDF]  

Consistent Genetic Alterations in Xenografts of Proximal Stomach and Gastro-Esophageal Junction Adenocarcinomas

Wa'el El-Rifai, Jeffrey C. Harper, Oscar W. Cummings, Eija-Riitta Hyytinen, Henry F. Frierson, Jr., Sakari Knuutila, and Steven M. Powell
Cancer Res 1998 58: 34-37. [Abstract] [PDF]  

DNA Adducts in Human Pancreatic Tissues and Their Potential Role in Carcinogenesis

Mianying Wang, James L. Abbruzzese, Helmut Friess, Walter N. Hittelman, Douglas B. Evans, Marie C. Abbruzzese, Paul Chiao, and Donghui Li
Cancer Res 1998 58: 38-41. [Abstract] [PDF]  

ß-Catenin Is Frequently Mutated and Demonstrates Altered Cellular Location in Azoxymethane-induced Rat Colon Tumors

Mami Takahashi, Kazunori Fukuda, Takashi Sugimura, and Keiji Wakabayashi
Cancer Res 1998 58: 42-46. [Abstract] [PDF]  

Carcinogenesis:

Activation of the Cyclic AMP Pathway by -Melanotropin Mediates the Response of Human Melanocytes to Ultraviolet B Radiation

Sungbin Im, Osamu Moro, Fuping Peng, Estela E. Medrano, James Cornelius, George Babcock, James J. Nordlund, and Zalfa A. Abdel-Malek
Cancer Res 1998 58: 47-54. [Abstract] [PDF]  

Clinical Investigations:

Rearrangement of ALL1 (MLL) in Acute Myeloid Leukemia with Normal Cytogenetics

Michael A. Caligiuri, Matthew P. Strout, David Lawrence, Diane C. Arthur, Maria R. Baer, Feng Yu, Sakari Knuutila, Krzysztof Mrózek, Adam R. Oberkircher, Guido Marcucci, Albert de la Chapelle, Erkki Elonen, AnneMarie W. Block, P. Nagesh Rao, Geoffrey P. Herzig, Bayard L. Powell, Tapani Ruutu, Charles A. Schiffer, and Clara D. Bloomfield
Cancer Res 1998 58: 55-59. [Abstract] [PDF]  

Endocrinology:

Comparison of the Effects of the Antiestrogens EM-800 and Tamoxifen on the Growth of Human Breast ZR-75-1 Cancer Xenografts in Nude Mice

Steeve Couillard, Matthieu Gutman, Claude Labrie, Alain Bélanger, Bernard Candas, and Fernand Labrie
Cancer Res 1998 58: 60-64. [Abstract] [PDF]  

Epidemiology and Prevention:

Breast Cancer and CYPIA1, GSTM1, and GSTT1 Polymorphisms: Evidence of a Lack of Association in Caucasians and African Americans

L. Renee Bailey, Nady Roodi, Carmel S. Verrier, Cindy J. Yee, William D. Dupont, and Fritz F. Parl
Cancer Res 1998 58: 65-70. [Abstract] [PDF]  

Experimental Therapeutics:

Photoactivation Enhances the Mitochondrial Toxicity of the Cationic Rhoadcyanine MKT-077

Josephine S. Modica-Napolitano, Brian T. Brunelli, Keizo Koya, and Lan Bo Chen
Cancer Res 1998 58: 71-75. [Abstract] [PDF]  

Caspase-7 Is Activated during Lovastatin-induced Apoptosis of the Prostate Cancer Cell Line LNCaP

Marco Marcelli, Glenn R. Cunningham, S. Joe Haidacher, Sebastian J. Padayatty, Lydia Sturgis, Carolina Kagan, and Larry Denner
Cancer Res 1998 58: 76-83. [Abstract] [PDF]  

Molecular Biology and Genetics:

The Radiosensitive Cell Line 180BR Is Not Defective in the Major DNA Damage-sensing Proteins

Hong Lu, Qizhong Song, Colin Arlett, and Martin F. Lavin
Cancer Res 1998 58: 84-88. [Abstract] [PDF]  

Disruption of the Mouse Xeroderma Pigmentosum Group D DNA Repair/Basal Transcription Gene Results in Preimplantation Lethality

Jan de Boer, Ingrid Donker, Jan de Wit, Jan H. J. Hoeijmakers, and Geert Weeda
Cancer Res 1998 58: 89-94. [Abstract] [PDF]  

Inhibition of DNA Methylation by 5-Aza-2'-deoxycytidine Suppresses the Growth of Human Tumor Cell Lines

Christina M. Bender, Martha M. Pao, and Peter A. Jones
Cancer Res 1998 58: 95-101. [Abstract] [PDF]  

Cyclobutane Pyrimidine Dimers are the Main Mutagenic DNA Photoproducts in DNA Repair-deficient Trichothiodystrophy Cells

Claire Marionnet, Jacques Armier, Alain Sarasin, and Anne Stary
Cancer Res 1998 58: 102-108. [Abstract] [PDF]  

Novel Mutations in the p16/CDKN2A Binding Region of the Cyclin-dependent Kinase-4 Gene

Hensin Tsao, Eric Benoit, Arthur J. Sober, Carol Thiele, and Frank G. Haluska
Cancer Res 1998 58: 109-113. [Abstract] [PDF]  

Localization and Expression of p27^KIP1 in Multistage Colorectal Carcinogenesis

Marco Ciaparrone, Hirofumi Yamamoto, Yao Yao, Alessandro Sgambato, Giorgio Cattoretti, Naohiro Tomita, Takushi Monden, Heidrun Rotterdam, and I. Bernard Weinstein
Cancer Res 1998 58: 114-122. [Abstract] [PDF]  

Disruption of the pRb/E2F Pathway and Inhibition of Apoptosis Are Major Oncogenic Events in Liver Constitutively Expressing c-myc and Transforming Growth Factor

Eric Santoni-Rugiu, Michael Rugaard Jensen, and Snorri S. Thorgeirsson
Cancer Res 1998 58: 123-134. [Abstract] [PDF]  

Tumor Biology:

N-(2-Chloroethyl)-N'-cyclohexyl-N-nitrosourea Sensitivity in Mismatch Repair-defective Human Cells

Gabriele Aquilina, Sabrina Ceccotti, Simone Martinelli, Richard Hampson, and Marherita Bignami
Cancer Res 1998 58: 135-141. [Abstract] [PDF]  

Retinoic Acid Receptor ß Induces Terminal Differentiation of Squamous Cell Carcinoma Lines in the Absence of Cyclin-dependent Kinase Inhibitor Expression

David L. Crowe
Cancer Res 1998 58: 142-148. [Abstract] [PDF]  

Spreading and Migration of Human Glioma and Rat C6 Cells on Central Nervous System Myelin in Vitro Is Correlated with Tumor Malignancy and Involves a Metalloproteolytic Activity

Verena R. Amberger, Tamara Hensel, Nobuyoshi Ogata, and Martin E. Schwab
Cancer Res 1998 58: 149-158. [Abstract] [PDF]  

Modulation of Enhanced Vascular Permeability in Tumors by a Bradykinin Antagonist, a Cyclooxygenase Inhibitor, and a Nitric Oxide Scavenger

Jun Wu, Takaaki Akaike, and Hiroshi Maeda
Cancer Res 1998 58: 159-165. [Abstract] [PDF]  

Metabolism of all-trans-Retinol in Normal Human Cell Strains and Squamous Cell Carcinoma (SCC) Lines from the Oral Cavity and Skin: Reduced Esterification of Retinol in SCC Lines

Xiaojia Guo and Lorraine J. Gudas
Cancer Res 1998 58: 166-176. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1998 58: 177 [PDF]  

Recent Death

Cancer Res 1998 58: 177 [PDF]  

Calendar of Events

Cancer Res 1998 58: 178-179. [PDF]  

Materials and Methods

Cancer Res 1998 58: 179 [PDF]  

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