Perspectives in Cancer Research:

Is 2-Methoxyestradiol an Endogenous Estrogen Metabolite That Inhibits Mammary Carcinogenesis?

Bao Ting Zhu and Allan H. Conney
Cancer Res 1998 58: 2269-2277. [Abstract] [PDF]  

Advances in Brief:

Genomic Changes in Endometrial Polyps Associated with Tamoxifen Show No Evidence for Its Action as an External Carcinogen

Paola Dal Cin, Dirk Timmerman, Ivo Van den Berghe, Sylke Wanschura, Bernd Kazmierczak, Ignace Vergote, Jan Deprest, Patrick Neven, Philippe Moerman, Jörn Bullerdiek, and Herman Van den Berghe
Cancer Res 1998 58: 2278-2281. [Abstract] [PDF]  

Prostate-specific Amplification of Expanded Polyglutamine Expression: A Novel Approach for Cancer Gene Therapy

Takehiko Segawa, Hirohide Takebayashi, Yoshiyuki Kakehi, Osamu Yoshida, Shuh Narumiya, and Akira Kakizuka
Cancer Res 1998 58: 2282-2287. [Abstract] [PDF]  

Adenovirus-mediated Wild-Type p53 Gene Transfer Down-Regulates Vascular Endothelial Growth Factor Expression and Inhibits Angiogenesis in Human Colon Cancer

Michael Bouvet, Lee M. Ellis, Masahiko Nishizaki, Toshiyoshi Fujiwara, Wenbiao Liu, Corazon D. Bucana, Bingliang Fang, J. Jack Lee, and Jack A. Roth
Cancer Res 1998 58: 2288-2292. [Abstract] [PDF]  

Ataxia-telangiectasia and T-Cell Leukemias: No Evidence for Somatic ATM Mutation in Sporadic T-ALL or for Hypermethylation of the ATM-NPAT/E14 Bidirectional Promoter in T-PLL

Liping Luo, Feng-min Lu, Steve Hart, Letizia Foroni, Hodjattallah Rabbani, Lennart Hammarström, A. David B. Webster, and Igor Vorechovsky
Cancer Res 1998 58: 2293-2297. [Abstract] [PDF]  

Germ-Line Deletion Involving the INK4 Locus in Familial Proneness to Melanoma and Nervous System Tumors

Michel Bahuau, Dominique Vidaud, Robert B. Jenkins, Ivan Bièche, David W. Kimmel, Brigitte Assouline, Justin S. Smith, Benjamin Alderete, Jean-Michel Cayuela, Jean-Paul Harpey, Bernard Caille, and Michel Vidaud
Cancer Res 1998 58: 2298-2303. [Abstract] [PDF]  

Intratumoral Heterogeneity of Von Hippel-Lindau Gene Deletions in Renal Cell Carcinoma Detected by Fluorescence in Situ Hybridization

Holger Moch, Peter Schraml, Lukas Bubendorf, Jan Richter, Thomas C. Gasser, Michael J. Mihatsch, and Guido Sauter
Cancer Res 1998 58: 2304-2309. [Abstract] [PDF]  

Adenovirus-mediated Gene Delivery of Tissue Inhibitor of Metalloproteinases-3 Inhibits Invasion and Induces Apoptosis in Melanoma Cells

Matti Ahonen, Andrew H. Baker, and Veli-Matti Kähäri
Cancer Res 1998 58: 2310-2315. [Abstract] [PDF]  

Characterization of Cell Cycle Checkpoint Responses after Ionizing Radiation in Nijmegen Breakage Syndrome Cells

Vikky Yamazaki, Rolf-Dieter Wegner, and Cordula U. Kirchgessner
Cancer Res 1998 58: 2316-2322. [Abstract] [PDF]  

Antioxidants Reduce Cyclooxygenase-2 Expression, Prostaglandin Production, and Proliferation in Colorectal Cancer Cells

Rebecca Chinery, R. Daniel Beauchamp, Yu Shyr, Susan C. Kirkland, Robert J. Coffey, and Jason D. Morrow
Cancer Res 1998 58: 2323-2327. [Abstract] [PDF]  

Evidence for the Multifocal Origin of Bilateral and Advanced Human Serous Borderline Ovarian Tumors

Karen H. Lu, Debra A. Bell, William R. Welch, Ross S. Berkowitz, and Samuel C. Mok
Cancer Res 1998 58: 2328-2330. [Abstract] [PDF]  

Suppression of Tumorigenicity of Glioblastoma Cells by Adenovirus-mediated MMAC1/PTEN Gene Transfer

I. Wayne Cheney, Duane E. Johnson, Mei-Ting Vaillancourt, Jenny Avanzini, Alyssa Morimoto, G. William Demers, Ken N. Wills, Paul W. Shabram, Joseph B. Bolen, Sean V. Tavtigian, and Robert Bookstein
Cancer Res 1998 58: 2331-2334. [Abstract] [PDF]  

Activation of Nuclear Factor B: Potential Role in Metallothionein-mediated Mitogenic Response

Asim B. Abdel-Mageed and Krishna C. Agrawal
Cancer Res 1998 58: 2335-2338. [Abstract] [PDF]  

Alterations in Pancreatic, Biliary, and Breast Carcinomas Support MKK4 as a Genetically Targeted Tumor Suppressor Gene

Gloria H. Su, Werner Hilgers, Manu C. Shekher, David J. Tang, Charles J. Yeo, Ralph H. Hruban, and Scott E. Kern
Cancer Res 1998 58: 2339-2342. [Abstract] [PDF]  

Apoptosis and Tumor Angiogenesis in Cervical Cancer after Preoperative Chemotherapy

Masatsugu Ueda, Ken Ueki, Koji Kumagai, Yoshito Terai, Yoshiaki Okamoto, Minoru Ueki, and Yoshinori Otsuki
Cancer Res 1998 58: 2343-2346. [Abstract] [PDF]  

Activation of p73 Silent Allel in Lung Cancer

Ming Mai, Akira Yokomizo, Chiping Qian, Ping Yang, Donald J. Tindall, David I. Smith, and Wanguo Liu
Cancer Res 1998 58: 2347-2349. [Abstract] [PDF]  

Metastasis Suppression by the Standard CD44 Isoform Does Not Require the Binding of Prostate Cancer Cells to Hyaluronate

Allen C. Gao, Wei Lou, Jonathan P. Sleeman, and John T. Isaacs
Cancer Res 1998 58: 2350-2352. [Abstract] [PDF]  

Biochemistry and Biophysics:

Purification and Characterization of a Tumor Lipid-mobilizing Factor

Penio T. Todorov, Trudi M. McDevitt, David J. Meyer, Hisao Ueyama, Iwao Ohkubo, and Michael J. Tisdale
Cancer Res 1998 58: 2353-2358. [Abstract] [PDF]  

Biological Evaluation of a Lipid-mobilizing Factor Isolated from the Urine of Cancer Patients

Kouzo Hirai, Helen J. Hussey, Matthew D. Barber, Sarah A. Price, and Michael J. Tisdale
Cancer Res 1998 58: 2359-2365. [Abstract] [PDF]  

Carcinogenesis:

Characterization of CYP1B1 and CYP1A1 Expression in Human Mammary Epithelial Cells: Role of the Aryl Hydrocarbon Receptor in Polycyclic Aromatic Hydrocarbon Metabolism

Michele Campaigne Larsen, William G. R. Angus, Paul B. Brake, Sakina E. Eltom, Kristine A. Sukow, and Colin R. Jefcoate
Cancer Res 1998 58: 2366-2374. [Abstract] [PDF]  

Clinical Investigations:

Determination of Somatostatin Receptor Subtype 2 in Carcinoid Tumors by Immunohistochemical Investigation with Somatostatin Receptor Subtype 2 Antibodies

Eva Tiensuu Janson, Mats Stridsberg, Anders Gobl, Jan-Erik Westlin, and Kjell Öberg
Cancer Res 1998 58: 2375-2378. [Abstract] [PDF]  

Endocrinology:

Increased UDP-glucuronosyltransferase Activity and Decreased Prostate Specific Antigen Production by Biochanin A in Prostate Cancer Cells

Xiao-Ya Sun, Cathie A. Plouzek, James P. Henry, Thomas T. Y. Wang, and James M. Phang
Cancer Res 1998 58: 2379-2384. [Abstract] [PDF]  

Experimental Therapeutics:

Metabolism of 17-(Allylamino)-17-demethoxygeldanamycin (NSC 330507) by Murine and Human Hepatic Preparations

Merrill J. Egorin, D. Marc Rosen, Jordan H. Wolff, Patrick S. Callery, Steven M. Musser, and Julie L. Eiseman
Cancer Res 1998 58: 2385-2396. [Abstract] [PDF]  

Tyrphostin 4-Nitrobenzylidene Malononitrile Reduces Chemotherapy Toxicity without Impairing Efficacy

Abraham Novogrodsky, Michael Weisspapir, Miriam Patya, Asher Meshorer, and Alexey Vanichkin
Cancer Res 1998 58: 2397-2403. [Abstract] [PDF]  

Complete Regression of Well-established Tumors Using a Novel Water-soluble Poly(L-Glutamic Acid)-Paclitaxel Conjugate

Chun Li, Dong-Fang Yu, Robert A. Newman, Fernando Cabral, L. Clifton Stephens, Nancy Hunter, Luka Milas, and Sidney Wallace
Cancer Res 1998 58: 2404-2409. [Abstract] [PDF]  

Comparative Pharmacology of the Novel Cyclopropylpyrroloindole-Prodrug Carzelesin in Mice, Rats, and Humans

Olaf van Tellingen, Willem J. Nooijen, Larry J. Schaaf, Martin van der Valk, Judith van Asperen, Roland E. C. Henrar, and Jos H. Beijnen
Cancer Res 1998 58: 2410-2416. [Abstract] [PDF]  

Immunology:

Characterization of Human Anti-High Molecular Weight-Melanoma-associated Antigen Single-Chain Fv Fragments Isolated from a Phage Display Antibody Library

Smruti A. Desai, Xinhui Wang, Elvyra J. Noronha, Toshiro Kageshita, and Soldano Ferrone
Cancer Res 1998 58: 2417-2425. [Abstract] [PDF]  

Multiple Roles of Interferon- in the Mediation of Interleukin 12-induced Tumor Regression

Makoto Ogawa, Wen-Gong Yu, Kazunari Umehara, Masayuki Iwasaki, Rishani Wijesuriya, Takahiro Tsujimura, Takeshi Kubo, Hiromi Fujiwara, and Toshiyuki Hamaoka
Cancer Res 1998 58: 2426-2432. [Abstract] [PDF]  

Peptides Derived from Self-Proteins as Partial Agonists and Antagonists of Human CD8⁺ T-Cell Clones Reactive to Melanoma/Melanocyte Epitope MART1_27–35

Douglas J. Loftus, Paola Squarcina, Mai-Britt Nielsen, Carsten Geisler, Chiara Castelli, Niels Ødum, Ettore Appella, Giorgio Parmiani, and Licia Rivoltini
Cancer Res 1998 58: 2433-2439. [Abstract] [PDF]  

Molecular Biology and Genetics:

Identification of a Novel Gene Marker Specific for Epithelial Cells by Utilizing a 3'-directed cDNA Library

Tadashi Ohnishi, Naohiro Tomita, Yasuo Miyoshi, Nobutoshi Shinoki, Tatsuya Tanaka, Yuichi Kawabata, Mitsugu Sekimoto, Takushi Monden, Kousaku Okubo, Kenichi Matsubara, and Morito Monden
Cancer Res 1998 58: 2440-2444. [Abstract] [PDF]  

Defective Bypass Replication of a Leading Strand Cyclobutane Thymine Dimer in Xeroderma Pigmentosum Variant Cell Extracts

Daniel L. Svoboda, Linda P. Briley, and Jean-Michel H. Vos
Cancer Res 1998 58: 2445-2448. [Abstract] [PDF]  

Clones of Normal Keratinocytes and a Variety of Simultaneously Present Epidermal Neoplastic Lesions Contain a Multitude of p53 Gene Mutations in a Xeroderma Pigmentosum Patient

Cecilia Williams, Fredrik Pontén, Afshin Ahmadian, Zhi-Ping Ren, Gao Ling, Ola Rollman, Anders Ljung, Nicholaas G. J. Jaspers, Mathias Uhlén, Joakim Lundeberg, and Jan Pontén
Cancer Res 1998 58: 2449-2455. [Abstract] [PDF]  

Identification of Two Common Regions of Allelic Loss in Chromosome Arm 12q in Human Pancreatic Cancer

Mitsuhiro Kimura, Toru Furukawa, Tadayoshi Abe, Toshimasa Yatsuoka, Emile M. Youssef, Tadaaki Yokoyama, Hong Ouyang, Yasuyuki Ohnishi, Makoto Sunamura, Masao Kobari, Seiki Matsuno, and Akira Horii
Cancer Res 1998 58: 2456-2460. [Abstract] [PDF]  

Expression of Early Growth Response Genes in Human Prostate Cancer

Manal A. Eid, M. Vijay Kumar, Kenneth A. Iczkowski, David G. Bostwick, and Donald J. Tindall
Cancer Res 1998 58: 2461-2468. [Abstract] [PDF]  

Tumor Biology:

The Ewing Tumor Family of Peripheral Primitive Neuroectodermal Tumors Expresses Human Gastrin-releasing Peptide

Elizabeth R. Lawlor, Jerian F. Lim, Wen Tao, Christopher Poremba, Clinton J. Chow, Ingrid V. Kalousek, Heinrich Kovar, Tom J. MacDonald, and Poul H. B. Sorensen
Cancer Res 1998 58: 2469-2476. [Abstract] [PDF]  

Inhibition of Tumorigenesis and Induction of Apoptosis in Human Tumor Cells by the Stable Expression of a Myristylated COOH Terminus of the Insulin-like Growth Factor I Receptor

Atsushi Hongo, Gladys Yumet, Mariana Resnicoff, Gaetano Romano, Rosemary O'Connor, and Renato Baserga
Cancer Res 1998 58: 2477-2484. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1998 58: 2485-2487. [PDF]  

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