Advances in Brief:

No Association of the I1307K APC Allele with Ovarian Cancer Risk in Ashkenazi Jews

John Abrahamson, Roxana Moslehi, Danny Vesprini, Beth Karlan, David Fishman, David Smotkin, Yehuda Ben David, Haim Biran, Abbie Fields, Jean-Sebastien Brunet, and Steven A. Narod
Cancer Res 1998 58: 2919-2922. [Abstract] [PDF]  

The APC Gene I1307K Variant Is Rare in Norwegian Patients with Familial and Sporadic Colorectal or Breast Cancer

Ragnhild A. Lothe, Merete Hektoen, Hilde Johnsen, Gunn Iren Meling, Tone Ikdahl Andersen, Torleiv O. Rognum, Annika Lindblom, and Anne-Lise Børresen-Dale
Cancer Res 1998 58: 2923-2924. [Abstract] [PDF]  

Targeted Therapy with a Novel Enediyene Antibiotic Calicheamicin ^I₁ Effectively Suppresses Growth and Dissemination of Liver Metastases in a Syngeneic Model of Murine Neuroblastoma

Holger N. Lode, Ralph A. Reisfeld, Rupert Handgretinger, Kyriacos C. Nicolaou, Gerhard Gaedicke, and Wolfgang Wrasidlo
Cancer Res 1998 58: 2925-2928. [Abstract] [PDF]  

Increased Expression of Inducible Nitric Oxide Synthase and Cyclooxygenase-2 in Barrett's Esophagus and Associated Adenocarcinomas

Keith T. Wilson, Sidong Fu, Kalathur S. Ramanujam, and Stephen J. Meltzer
Cancer Res 1998 58: 2929-2934. [Abstract] [PDF]  

A Novel Model of Glioma Cell Invasion Using Organotypic Brain Slice Culture

Takanori Ohnishi, Hirotaka Matsumura, Shuichi Izumoto, Shoju Hiraga, and Toru Hayakawa
Cancer Res 1998 58: 2935-2940. [Abstract] [PDF]  

Differential Cell Cycle Regulation by Low- and High-Risk Human Papillomaviruses in Low-Grade Squamous Intraepithelial Lesions of the Cervix

Shirley A. Southern and C. Simon Herrington
Cancer Res 1998 58: 2941-2945. [Abstract] [PDF]  

Absence or Reduction of Fhit Expression in Most Clear Cell Renal Carcinomas

Piotr Hadaczek, Zurab Siprashvili, Maciej Markiewski, Wenancjusz Domagala, Teresa Druck, Peter A. McCue, Yuri Pekarsky, Masataka Ohta, Kay Huebner, and Jan Lubinski
Cancer Res 1998 58: 2946-2951. [Abstract] [PDF]  

Receptor-mediated Folate Uptake Is Positively Regulated by Disruption of the Actin Cytoskeleton

Cheryl M. Lewis, Angela K. Smith, and Barton A. Kamen
Cancer Res 1998 58: 2952-2956. [Abstract] [PDF]  

Tissue Inhibitor of Metalloproteinase-2 Protection of Matrix Metalloproteinase-2 from Degradation by Plasmin Is Reversed by Divalent Cation Chelator EDTA and the Bisphosphonate Alendronate

Antonietta R. Farina, Antonella Tacconelli, Anna Teti, Alberto Gulino, and Andrew R. Mackay
Cancer Res 1998 58: 2957-2960. [Abstract] [PDF]  

Ultraviolet B-induced DNA Damage in Human Skin and Its Modulation by a Sunscreen

Vladimir J. Bykov, Jan A. Marcusson, and Kari Hemminki
Cancer Res 1998 58: 2961-2964. [Abstract] [PDF]  

Optimization of the Sequence of Antigen Loading and CD40-Ligand-induced Maturation of Dendritic Cells

Michael A. Morse, H. Kim Lyerly, Eli Gilboa, Elaine Thomas, and Smita K. Nair
Cancer Res 1998 58: 2965-2968. [Abstract] [PDF]  

The DAM Gene Family Encodes a New Group of Tumor-specific Antigens Recognized by Human Leukocyte Antigen A2-restricted Cytotoxic T Lymphocytes

Katharina Fleischhauer, Luca Gattinoni, Piero Dalerba, Grégoire Lauvau, Elena Zanaria, Branca Dabovic, Peter M. van Endert, Claudio Bordignon, and Catia Traversari
Cancer Res 1998 58: 2969-2972. [Abstract] [PDF]  

AKT2, a Member of the Protein Kinase B Family, Is Activated by Growth Factors, v-Ha-ras, and v-src through Phosphatidylinositol 3-Kinase in Human Ovarian Epithelial Cancer Cells

Ai-xue Liu, Joseph R. Testa, Thomas C. Hamilton, Richard Jove, Santo V. Nicosia, and Jin Q. Cheng
Cancer Res 1998 58: 2973-2977. [Abstract] [PDF]  

Single Gene Complementation of the hPMS2 Defect in HEC-1-A Endometrial Carcinoma Cells

John I. Risinger, Asad Umar, Warren E. Glaab, Kenneth R. Tindall, Thomas A. Kunkel, and J. Carl Barrett
Cancer Res 1998 58: 2978-2981. [Abstract] [PDF]  

Interstitial Methotrexate Kinetics in Primary Breast Cancer Lesions

Markus Müller, Martin Brunner, Rainer Schmid, Robert M. Mader, Julia Bockenheimer, Günther G. Steger, Birgit Steiner, Hans G. Eichler, and Brigitte Blöchl-Daum
Cancer Res 1998 58: 2982-2985. [Abstract] [PDF]  

Interaction between the Protein Kinase B-Raf and the -Subunit of the 11S Proteasome Regulator

Andreas Kalmes, Carsten Hagemann, Christoph K. Weber, Ludmilla Wixler, Tillman Schuster, and Ulf R. Rapp
Cancer Res 1998 58: 2986-2990. [Abstract] [PDF]  

Presence of Streptococcus anginosus DNA in Esophageal Cancer, Dysplasia of Esophagus, and Gastric Cancer

Hiroki Sasaki, Tomoki Ishizuka, Manabu Muto, Masahiko Nezu, Yukihiro Nakanishi, Yoshishige Inagaki, Haruo Watanabe, Hiroshi Watanabe, and Masaaki Terada
Cancer Res 1998 58: 2991-2995. [Abstract] [PDF]  

Biochemistry and Biophysics:

11ß-Hydroxysteroid Dehydrogenase Responsible for Carbonyl Reduction of the Tobacco-specific Nitrosamine 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone in Mouse Lung Microsomes

Edmund Maser
Cancer Res 1998 58: 2996-3003. [Abstract] [PDF]  

In Situ Cross-Linking by Cisplatin of Nuclear Matrix-bound Transcription Factors to Nuclear DNA of Human Breast Cancer Cells

Shanti K. Samuel, Virginia A. Spencer, Lydia Bajno, Jian-Min Sun, Laurel T. Holth, Steffi Oesterreich, and James R. Davie
Cancer Res 1998 58: 3004-3008. [Abstract] [PDF]  

Clinical Investigations:

Positron Emission Tomography of a Human Prostate Cancer Xenograft: Association of Changes in Deoxyglucose Accumulation with Other Measures of Outcome following Androgen Withdrawal

David B. Agus, David W. Golde, George Sgouros, Ase Ballangrud, Carlos Cordon-Cardo, and Howard I. Scher
Cancer Res 1998 58: 3009-3014. [Abstract] [PDF]  

Endocrinology:

Galectin-3 Is a Presurgical Marker of Human Thyroid Carcinoma

Fabio Orlandi, Enrico Saggiorato, Giovanni Pivano, Barbara Puligheddu, Angela Termine, Susanna Cappia, Paolo De Giuli, and Alberto Angeli
Cancer Res 1998 58: 3015-3020. [Abstract] [PDF]  

Stimulation of Tumor Growth by Recombinant Human Insulin-like Growth Factor-I (IGF-I) Is Dependent on the Dose and the Level of IGF-I Receptor Expression

Andrew A. Butler, Vicky A. Blakesley, Maria Tsokos, Vasiliki Pouliki, Teresa L. Wood, and Derek LeRoith
Cancer Res 1998 58: 3021-3027. [Abstract] [PDF]  

Epidemiology and Prevention:

Chemopreventive Effects of Nimesulide, a Selective Cyclooxygenase-2 Inhibitor, on the Development of Rat Urinary Bladder Carcinomas Initiated by N-Butyl-N-(4-hydroxybutyl)nitrosamine

Eijiro Okajima, Ayumi Denda, Seiichiro Ozono, Makoto Takahama, Hiroyuki Akai, Yasutaka Sasaki, Wakashi Kitayama, Keiji Wakabayashi, and Yoichi Konishi
Cancer Res 1998 58: 3028-3031. [Abstract] [PDF]  

Increased Risk of Hepatoblastoma among Immature Children with a Lower Birth Weight

Masako Tanimura, Ichiro Matsui, Jun Abe, Hitoshi Ikeda, Noboru Kobayashi, Mutsuro Ohira, Masaru Yokoyama, and Michio Kaneko
Cancer Res 1998 58: 3032-3035. [Abstract] [PDF]  

Experimental Therapeutics:

Super in Vitro Synergy between Inhibitors of Dihydrofolate Reductase and Inhibitors of Other Folate-requiring Enzymes: The Critical Role of Polyglutamylation

Hélène M. Faessel, Harry K. Slocum, Robert C. Jackson, Theodore J. Boritzki, Youcef M. Rustum, M. G. Nair, and William R. Greco
Cancer Res 1998 58: 3036-3050. [Abstract] [PDF]  

Evaluating Antibodies for Their Capacity to Induce Cell-mediated Lysis of Malignant B Cells

Dieter Würflein, Michael Dechant, Bernhard Stockmeyer, Alison L. Tutt, Peisheng Hu, Roland Repp, Joachim R. Kalden, Jan G. J. van de Winkel, Alan L. Epstein, Thomas Valerius, Martin Glennie, and Martin Gramatzki
Cancer Res 1998 58: 3051-3058. [Abstract] [PDF]  

Prevention of Brefeldin A-induced Resistance to Teniposide by the Proteasome Inhibitor MG-132: Involvement of NF-B Activation in Drug Resistance

Z. Ping Lin, Yoonkyung C. Boller, Suad M. Amer, Rosalind L. Russell, Karen A. Pacelli, Steven R. Patierno, and Katherine A. Kennedy
Cancer Res 1998 58: 3059-3065. [Abstract] [PDF]  

Distinct Steps in DNA Fragmentation Pathway during Camptothecin-induced Apoptosis Involved Caspase-, Benzyloxycarbonyl- and N-Tosyl-L-Phenylalanylchloromethyl Ketone-sensitive Activities

Alain-Théophile Sané and Richard Bertrand
Cancer Res 1998 58: 3066-3072. [Abstract] [PDF]  

Immunology:

Role of the Endogenous Production of Interleukin 12 in Immunotherapy

Mamoru Harada, Koji Tamada, Koichiro Abe, Kosei Yasumoto, Genki Kimura, and Kikuo Nomoto
Cancer Res 1998 58: 3073-3077. [Abstract] [PDF]  

Human Renal Cell Carcinoma Antigen-specific CTLs: Antigen-driven Selection and Long-Term Persistence in Vivo

Petra Jantzer and Dolores J. Schendel
Cancer Res 1998 58: 3078-3086. [Abstract] [PDF]  

Cryptic Open Reading Frames in Plasmid Vector Backbone Sequences Can Provide Highly Immunogenic Cytotoxic T-Lymphocyte Epitopes

Thorbald van Hall, Nastasja E. van de Rhee, Stephen P. Schoenberger, Michel P. M. Vierboom, Frank A. W. Verreck, Cornelis J. M. Melief, and Rienk Offringa
Cancer Res 1998 58: 3087-3093. [Abstract] [PDF]  

Efficient Direct Priming of Tumor-specific Cytotoxic T Lymphocyte in Vivo by an Engineered APC

Stephen P. Schoenberger, Liesbeth E. Jonges, Rob J. D. Mooijaart, Franca Hartgers, Rene E. M. Toes, W. Martin Kast, Cornelius J. M. Melief, and Rienk Offringa
Cancer Res 1998 58: 3094-3100. [Abstract] [PDF]  

Molecular Biology and Genetics:

Mutation of the Type II Transforming Growth Factor-ß Receptor Is Coincident with the Transformation of Human Colon Adenomas to Malignant Carcinomas

William M. Grady, Ashwani Rajput, Lois Myeroff, Dong F. Liu, KiHo Kwon, Joseph Willis, and Sanford Markowitz
Cancer Res 1998 58: 3101-3104. [Abstract] [PDF]  

Genetic Analysis of Ovarian Germ Cell Tumors by Comparative Genomic Hybridization

Maureen A. Riopel, Amy Spellerberg, Constance A. Griffin, and Elizabeth J. Perlman
Cancer Res 1998 58: 3105-3110. [Abstract] [PDF]  

DNA Double-Strand Breaks, p53, and Apoptosis during Lymphomagenesis in scid/scid Mice

Kay E. Gurley, Khoa Vo, and Christopher J. Kemp
Cancer Res 1998 58: 3111-3115. [Abstract] [PDF]  

Expression and Location of Hsp70/Hsc-Binding Anti-Apoptotic Protein BAG-1 and Its Variants in Normal Tissues and Tumor Cell Lines

Shinichi Takayama, Stanislaw Krajewski, Maryla Krajewska, Shinichi Kitada, Juan M. Zapata, Kristine Kochel, Deborah Knee, Dominic Scudiero, Gabriella Tudor, Gary J. Miller, Toshiyuki Miyashita, Masao Yamada, and John C. Reed
Cancer Res 1998 58: 3116-3131. [Abstract] [PDF]  

Tumor Biology:

Variable Expression of Cytokines in Human Head and Neck Squamous Cell Carcinoma Cell Lines and Consistent Expression in Surgical Specimens

Kendra V. Woods, Adel El-Naggar, Gary L. Clayman, and Elizabeth A. Grimm
Cancer Res 1998 58: 3132-3141. [Abstract] [PDF]  

Interleukin-1 Regulates Interleukin-6 Secretion in Human Oral Squamous Cell Carcinoma in Vitro: Possible Influence of p53 but not Human Papillomavirus E6/E7

Kendra V. Woods, Karen Adler-Storthz, Gary L. Clayman, Gail M. Francis, and Elizabeth A. Grimm
Cancer Res 1998 58: 3142-3149. [Abstract] [PDF]  

Differential Expression and Androgen Regulation of the Human Selenium-binding Protein Gene hSP56 in Prostate Cancer Cells

Meiheng Yang and Arthur J. Sytkowski
Cancer Res 1998 58: 3150-3153. [Abstract] [PDF]  

Differential Roles of Protein Kinase C and Pertussis Toxin-sensitive G-binding Proteins in Modulation of Melanoma Cell Proliferation and Motility by Thrombospondin 1

Neng-hua Guo, Vivian S. Zabrenetzky, Lakshmi Chandrasekaran, John M. Sipes, Jack Lawler, Henry C. Krutzsch, and David D. Roberts
Cancer Res 1998 58: 3154-3162. [Abstract] [PDF]  

Retinoic Acid Induced Mitogen-activated Protein (MAP)/Extracellular Signal-regulated Kinase (ERK) Kinase-dependent MAP Kinase Activation Needed to Elicit HL-60 Cell Differentiation and Growth Arrest

Andrew Yen, Mark S. Roberson, Susi Varvayanis, and Amy T. Lee
Cancer Res 1998 58: 3163-3172. [Abstract] [PDF]  

Expression of Signal Transducers and Activators of Transcription Proteins in Acute Myeloid Leukemia Blasts

Zheng Xia, Maria R. Baer, AnneMarie W. Block, Heinz Baumann, and Meir Wetzler
Cancer Res 1998 58: 3173-3180. [Abstract] [PDF]  

Adenosine and Other Low Molecular Weight Factors Released by Muscle Cells Inhibit Tumor Cell Growth

Pnina Fishman, Sara Bar-Yehuda, and Limor Vagman
Cancer Res 1998 58: 3181-3187. [Abstract] [PDF]  

Letters to the Editor:

Correspondence re: L. G. Boros et al., Oxythiamine and Dehydroepiandrosterone Inhibit the Nonoxidative Synthesis of Ribose and Tumor Cell Proliferation. Cancer Res., 57: 4242–4248, 1997: Letter

G. Kenneth Haines, III
Cancer Res 1998 58: 3188 [PDF]  

Correspondence re: L. G. Boros et al., Oxythiamine and Dehydroepiandrosterone Inhibit the Nonoxidative Synthesis of Ribose and Tumor Cell Proliferation. Cancer Res., 57: 4242–4248, 1997: Reply

Laszlo G. Boros
Cancer Res 1998 58: 3188 [PDF]  

Articles:

Announcements

Cancer Res 1998 58: 3189-3191. [PDF]  

Corrections

Vinata B. Lokeshwar
Cancer Res 1998 58: 3191 [PDF]  

Corrections

William Isaacs
Cancer Res 1998 58: 3191 [PDF]  

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