Advances in Brief:

Asbestos Increases Mammalian AP-Endonuclease Gene Expression, Protein Levels, and Enzyme Activity in Mesothelial Cells

Hua Fung, Yoke W. Kow, Bennett Van Houten, Douglas J. Taatjes, Zafer Hatahet, Yvonne M. W. Janssen, Pam Vacek, Stephen P. Faux, and Brooke T. Mossman
Cancer Res 1998 58: 189-194. [Abstract] [PDF]  

Use of Cardiac Troponin T Levels as an Indicator of Doxorubicin-induced Cardiotoxicity

Eugene H. Herman, Steven E. Lipshultz, Nader Rifai, Jun Zhang, Thomas Papoian, Zu-Xi Yu, Kazuyo Takeda, and Victor J. Ferrans
Cancer Res 1998 58: 195-197. [Abstract] [PDF]  

Detection of a Novel Type of RET Rearrangement (PTC5) in Thyroid Carcinomas after Chernobyl and Analysis of the Involved RET-fused Gene RFG5

Sabine Klugbauer, Evgenij P. Demidchik, Edmund Lengfelder, and Hartmut M. Rabes
Cancer Res 1998 58: 198-203. [Abstract] [PDF]  

Interfocal Heterogeneity of PTEN/MMAC1 Gene Alterations in Multiple Metastatic Prostate Cancer Tissues

Hiroyoshi Suzuki, Diha Freije, Deborah R. Nusskern, Kenji Okami, Paul Cairns, David Sidransky, William B. Isaacs, and G. Steven Bova
Cancer Res 1998 58: 204-209. [Abstract] [PDF]  

Expression of Estrogen Receptor ß Messenger RNA Variant in Breast Cancer

Esteban A. Vladusic, Ann E. Hornby, Fabiana K. Guerra-Vladusic, and Ruth Lupu
Cancer Res 1998 58: 210-214. [Abstract] [PDF]  

Reduction of Ventral Prostate Weight by Finasteride Is Associated with Suppression of Insulin-like Growth Factor I (IGF-I) and IGF-I Receptor Genes and with an Increase in IGF Binding Protein 3

Hung Huynh, Raouf M. Seyam, and Gerald B. Brock
Cancer Res 1998 58: 215-218. [Abstract] [PDF]  

In Vivo Transfection of Melanoma Cells by Lithotripter Shock Waves

Shiping Bao, Brian D. Thrall, Richard A. Gies, and Douglas L. Miller
Cancer Res 1998 58: 219-221. [Abstract] [PDF]  

Highly Sensitive Apurinic/Apyrimidinic Site Assay Can Detect Spontaneous and Chemically Induced Depurination under Physiological Conditions

Jun Nakamura, Vernon E. Walker, Patricia B. Upton, Su-Yin Chiang, Yoke W. Kow, and James A. Swenberg
Cancer Res 1998 58: 222-225. [Abstract] [PDF]  

Transforming Growth Factor Is a Target for the Von Hippel-Lindau Tumor Suppressor

Bertrand Knebelmann, Subbian Ananth, Herbert T. Cohen, and Vikas P. Sukhatme
Cancer Res 1998 58: 226-231. [Abstract] [PDF]  

Hevin, an Antiadhesive Extracellular Matrix Protein, Is Down-Regulated in Metastatic Prostate Adenocarcinoma

Peter S. Nelson, Stephen R. Plymate, Kai Wang, Lawrence D. True, Joy L. Ware, Lu Gan, Alvin Y. Liu, and Leroy Hood
Cancer Res 1998 58: 232-236. [Abstract] [PDF]  

Genetic Alterations in Gastrinomas and Nonfunctioning Pancreatic Neuroendocrine Tumors: An Analysis of p16/MTS1 Tumor Suppressor Gene Inactivation

Peter Muscarella, W. Scott Melvin, William E. Fisher, John Foor, E. Christopher Ellison, James G. Herman, William J. Schirmer, Charles L. Hitchcock, Barry R. DeYoung, and Christopher M. Weghorst
Cancer Res 1998 58: 237-240. [Abstract] [PDF]  

Biochemistry and Biophysics:

Transient Stimulation of the c-Jun-NH₂-Terminal Kinase/Activator Protein 1 Pathway and Inhibition of Extracellular Signal-regulated Kinase Are Early Effects in Paclitaxel-mediated Apoptosis in Human B Lymphoblasts

Stephen F. Amato, Jennifer M. Swart, Melissa Berg, Harold J. Wanebo, Shashi R. Mehta, and Thomas C. Chiles
Cancer Res 1998 58: 241-247. [Abstract] [PDF]  

Carcinogenesis:

Mouse Models for Hereditary Nonpolyposis Colorectal Cancer

Niels de Wind, Marleen Dekker, Agnes van Rossum, Martin van der Valk, and Hein te Riele
Cancer Res 1998 58: 248-255. [Abstract] [PDF]  

Clinical Investigations:

BCL-X Expression in Multiple Myeloma: Possible Indicator of Chemoresistance

Yiping Tu, Steven Renner, Feng-hao Xu, Alex Fleishman, Jeremy Taylor, Jeffrey Weisz, Robert Vescio, Matthew Rettig, James Berenson, Stanislaw Krajewski, John C. Reed, and Alan Lichtenstein
Cancer Res 1998 58: 256-262. [Abstract] [PDF]  

Endocrinology:

Partial Antagonism between Steroidal and Nonsteroidal Antiestrogens in Human Breast Cancer Cell Lines

Volkmar Müller, Elwood V. Jensen, and Cornelius Knabbe
Cancer Res 1998 58: 263-267. [Abstract] [PDF]  

Experimental Therapeutics:

Cross-Resistance to Methotrexate and Metals in Human Cisplatin-resistant Cell Lines Results from a Pleiotropic Defect in Accumulation of These Compounds Associated with Reduced Plasma Membrane Binding Proteins

Ding-wu Shen, Ira Pastan, and Michael M. Gottesman
Cancer Res 1998 58: 268-275. [Abstract] [PDF]  

Characterization of P-Glycoprotein Transport and Inhibition in Vivo

Eva Barbarics, James F. Kronauge, Dalia Cohen, Alan Davison, Alun G. Jones, and James M. Croop
Cancer Res 1998 58: 276-282. [Abstract] [PDF]  

c-myc Antisense Oligodeoxynucleotides Enhance the Efficacy of Cisplatin in Melanoma Chemotherapy in Vitro and in Nude Mice

Gennaro Citro, Igea D'Agnano, Carlo Leonetti, Roberto Perini, Barbara Bucci, Gerald Zon, Bruno Calabretta, and Gabriella Zupi
Cancer Res 1998 58: 283-289. [Abstract] [PDF]  

Antitumor Activity of Tumor Necrosis Factor Conjugated with Divinyl Ether and Maleic Anhydride Copolymer on Solid Tumors in Mice

Yoshihisa Kaneda, Yoko Yamamoto, Haruhiko Kamada, Shin-ichi Tsunoda, Yasuo Tsutsumi, Takashi Hirano, and Tadanori Mayumi
Cancer Res 1998 58: 290-295. [Abstract] [PDF]  

Immunology:

CD4⁺ T Cells from Peripheral Blood of a Melanoma Patient Recognize Peptides Derived from Nonmutated Tyrosinase

Hiroya Kobayashi, Taku Kokubo, Keisuke Sato, Shoji Kimura, Kazuhiro Asano, Hidetoshi Takahashi, Hajime Iizuka, Naoyuki Miyokawa, and Makoto Katagiri
Cancer Res 1998 58: 296-301. [Abstract] [PDF]  

Endogenous Expression of Transforming Growth Factor ß1 Inhibits Growth and Tumorigenicity and Enhances Fas-mediated Apoptosis in a Murine High-Grade Glioma Model

David M. Ashley, Feng M. Kong, Darell D. Bigner, and Laura P. Hale
Cancer Res 1998 58: 302-309. [Abstract] [PDF]  

Molecular Characterization of Antigen-processing Function in Nasopharyngeal Carcinoma (NPC): Evidence for Efficient Presentation of Epstein-Barr Virus Cytotoxic T-Cell Epitopes by NPC Cells

Rajiv Khanna, Pierre Busson, Scott R. Burrows, Colette Raffoux, Denis J. Moss, John M. Nicholls, and Leanne Cooper
Cancer Res 1998 58: 310-314. [Abstract] [PDF]  

Tolerance and Immunity to MUC1 in a Human MUC1 Transgenic Murine Model

Gerald J. Rowse, Richard M. Tempero, Michelle L. VanLith, Michael A. Hollingsworth, and Sandra J. Gendler
Cancer Res 1998 58: 315-321. [Abstract] [PDF]  

Molecular Biology and Genetics:

Frequent Loss of Gelsolin Expression in Non-Small Cell Lung Cancers of Heavy Smokers

Hirotoshi Dosaka-Akita, Fumihiro Hommura, Hisakazu Fujita, Ichiro Kinoshita, Motoi Nishi, Toshiaki Morikawa, Hiroyuki Katoh, Yoshikazu Kawakami, and Noboru Kuzumaki
Cancer Res 1998 58: 322-327. [Abstract] [PDF]  

High Frequency of Deletion mutations in p53 Gene from Squamous Cell Lung Cancer Patients in Taiwan

Yi-Ching Wang, Chih-Yi Chen, Shin-Kuang Chen, Shur-Hueih Cherng, William L. Ho, and Huei Lee
Cancer Res 1998 58: 328-333. [PDF]  

Tumor Biology:

Frequent Nitric Oxide Synthase-2 Expression in Human Colon Adenomas: Implication for Tumor Angiogenesis and Colon Cancer Progression

Stefan Ambs, William G. Merriam, William P. Bennett, Emanuela Felley-Bosco, Mofolusara O. Ogunfusika, Sean M. Oser, Shawn Klein, Peter G. Shields, Timothy R. Billiar, and Curtis C. Harris
Cancer Res 1998 58: 334-341. [Abstract] [PDF]  

Tumor Cell-associated Hyaluronan as an Unfavorable Prognostic Factor in Colorectal Cancer

Kirsi Ropponen, Markku Tammi, Jyrki Parkkinen, Matti Eskelinen, Raija Tammi, Pertti Lipponen, Ulla Ågren, Esko Alhava, and Veli-Matti Kosma
Cancer Res 1998 58: 342-347. [Abstract] [PDF]  

Insulin-like Growth Factor II Induced by Hypoxia May Contribute to Angiogenesis of Human Hepatocellular Carcinoma

Kyu-Won Kim, Soo-Kyung Bae, Ok-Hee Lee, Myung-Ho Bae, Myoung-Jin Lee, and Byung Chae Park
Cancer Res 1998 58: 348-351. [Abstract] [PDF]  

Both Autocrine and Paracrine Effects of Transfected Acidic Fibroblast Growth Factor Are Involved in the Estrogen-independent and Antiestrogen-resistant Growth of MCF-7 Breast Cancer Cells

Lurong Zhang, Samir Kharbanda, John Hanfelt, and Francis G. Kern
Cancer Res 1998 58: 352-361. [Abstract] [PDF]  

Modulation of Apoptosis and Bcl-2 Expression by Prostaglandin E₂ in Human Colon Cancer Cells

Hongmiao Sheng, Jinyi Shao, Jason D. Morrow, R. Daniel Beauchamp, and Raymond N. DuBois
Cancer Res 1998 58: 362-366. [Abstract] [PDF]  

Virology:

Persistent Human Cytomegalovirus Infection Induces Drug Resistance and Alteration of Programmed Cell Death in Human Neuroblastoma Cells

Jindrich Cinatl, Jr., Jaroslav Cinatl, Jens-Uwe Vogel, Ruslan Kotchetkov, Pablo Hernáiz Driever, Hana Kabickova, Bernhard Kornhuber, Dirk Schwabe, and Hans Wilhelm Doerr
Cancer Res 1998 58: 367-372. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1998 58: 373-374. [PDF]  

Corrections

Rafik Hanna, Gaik Lin Ong, and M. Jules Mattes
Cancer Res 1998 58: 375 [PDF]  

Corrections

Patricia L. M. Dahia and Charis Eng
Cancer Res 1998 58: 375 [PDF]  

Corrections

Giske Ursin, Brian Henderson, Robert W. Haile, Malcolm C. Pike, and Leslie Bernstein
Cancer Res 1998 58: 375 [PDF]  

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