Advances in Brief:

Expression of Cyclooxygenase-2 in Human Lung Carcinoma

Henrik Wolff, Kirsi Saukkonen, Sisko Anttila, Antti Karjalainen, Harri Vainio, and Ari Ristimäki
Cancer Res 1998 58: 4997-5001. [Abstract] [PDF]  

The Phosphoinositol Phosphatase Activity of PTEN Mediates a Serum-sensitive G₁ Growth Arrest in Glioma Cells

Frank B. Furnari, H-J. Su Huang, and Webster K. Cavenee
Cancer Res 1998 58: 5002-5008. [Abstract] [PDF]  

Gene Expression Profiling of Alveolar Rhabdomyosarcoma with cDNA Microarrays

Javed Khan, Richard Simon, Michael Bittner, Yidong Chen, Stephen B. Leighton, Thomas Pohida, Paul D. Smith, Yuan Jiang, Gerald C. Gooden, Jeffrey M. Trent, and Paul S. Meltzer
Cancer Res 1998 58: 5009-5013. [Abstract] [PDF]  

Cloning of the Human Aflatoxin B₁-Aldehyde Reductase Gene at 1p35-1p36.1 in a Region Frequently Altered in Human Tumor Cells

Christian Praml, Larissa Savelyeva, Patrizia Perri, and Manfred Schwab
Cancer Res 1998 58: 5014-5018. [Abstract] [PDF]  

Evidence of Cisplatin-induced Senescent-like Growth Arrest in Nasopharyngeal Carcinoma Cells

Xianghong Wang, Stephen C. H. Wong, Jie Pan, S. W. Tsao, Kevin H. Y. Fung, Dora L. W. Kwong, Jonathan S. T. Sham, and John M. Nicholls
Cancer Res 1998 58: 5019-5022. [Abstract] [PDF]  

Refined Chromosomal Localization of the Mismatch Repair and Hereditary Nonpolyposis Colorectal Cancer Genes hMSH2 and hMSH6

Christoph Schmutte, Rodica Catrinel Marinescu, Neal G. Copeland, Nancy A. Jenkins, Joan Overhauser, and Richard Fishel
Cancer Res 1998 58: 5023-5026. [Abstract] [PDF]  

Identification of a Human Gene Encoding a Homologue of Saccharomyces cerevisiae EXO1, an Exonuclease Implicated in Mismatch Repair and Recombination

Daniel X. Tishkoff, Neelam S. Amin, Carrie S. Viars, Karen C. Arden, and Richard D. Kolodner
Cancer Res 1998 58: 5027-5031. [Abstract] [PDF]  

Loss of FHIT Function in Lung Cancer and Preinvasive Bronchial Lesions

Gabriella Sozzi, Ugo Pastorino, Luisa Moiraghi, Elda Tagliabue, Francesco Pezzella, Cristina Ghirelli, Silvana Tornielli, Laura Sard, Kay Huebner, Marco A. Pierotti, Carlo M. Croce, and Silvana Pilotti
Cancer Res 1998 58: 5032-5037. [Abstract] [PDF]  

Association of Cytochrome P450 1B1 (CYP1B1) Polymorphism with Steroid Receptor Status in Breast Cancer

L. Renee Bailey, Nady Roodi, William D. Dupont, and Fritz F. Parl
Cancer Res 1998 58: 5038-5041. [Abstract] [PDF]  

Comparative Genomic Hybridization Analysis of Chromosomal Alterations Induced by the Development of Resistance to Thymidylate Synthase Inhibitors

Patrick H. Rooney, David A. J. Stevenson, Sharon Marsh, Patrick G. Johnston, Neva E. Haites, James Cassidy, and Howard L. McLeod
Cancer Res 1998 58: 5042-5045. [Abstract] [PDF]  

ETV6-NTRK3 Gene Fusions and Trisomy 11 Establish a Histogenetic Link between Mesoblastic Nephroma and Congenital Fibrosarcoma

Stevan R. Knezevich, Mathew J. Garnett, Theodore J. Pysher, J. Bruce Beckwith, Paul E. Grundy, and Poul H. B. Sorensen
Cancer Res 1998 58: 5046-5048. [Abstract] [PDF]  

The COOH-terminal Region of pRb2/p130 Binds to Histone Deacetylase 1 (HDAC1), Enhancing Transcriptional Repression of the E2F-dependent Cyclin A Promoter

Peter Stiegler, Antonio De Luca, Luigi Bagella, and Antonio Giordano
Cancer Res 1998 58: 5049-5052. [Abstract] [PDF]  

p21^WAF1/CIP1 Mutants Deficient in Inhibiting Cyclin-dependent Kinases (CDKs) Can Promote Assembly of Active Cyclin D/CDK4(6) Complexes in Human Tumor Cells

Markus Welcker, Jiri Lukas, Michael Strauss, and Jiri Bartek
Cancer Res 1998 58: 5053-5056. [Abstract] [PDF]  

Nuclear but not Cytoplasmic Phospholipase C ß₁ Inhibits Differentiation of Erythroleukemia Cells

Alessandro Matteucci, Irene Faenza, R. Stewart Gilmour, Lucia Manzoli, Anna Maria Billi, Daniela Peruzzi, Alberto Bavelloni, Sue-Goo Rhee, and Lucio Cocco
Cancer Res 1998 58: 5057-5060. [Abstract] [PDF]  

The Potential Tumor Suppressor p73 Differentially Regulates Cellular p53 Target Genes

Jianhui Zhu, Jieyuan Jiang, Wenjing Zhou, and Xinbin Chen
Cancer Res 1998 58: 5061-5065. [Abstract] [PDF]  

Naturally Processed Class II Epitope from the Tumor Antigen MUC1 Primes Human CD4⁺ T Cells

Elizabeth M. Hiltbold, Pawel Ciborowski, and Olivera J. Finn
Cancer Res 1998 58: 5066-5070. [Abstract] [PDF]  

Inhibition of Apoptosis by Survivin Predicts Shorter Survival Rates in Colorectal Cancer

Hiroshi Kawasaki, Dario C. Altieri, Cai-De Lu, Masao Toyoda, Toshiyuki Tenjo, and Nobuhiko Tanigawa
Cancer Res 1998 58: 5071-5074. [Abstract] [PDF]  

Functional Interactions of p53 with Poly(ADP-ribose) Polymerase (PARP) during Apoptosis following DNA Damage: Covalent Poly(ADP-ribosyl)ation of p53 by Exogenous PARP and Noncovalent Binding of p53 to the M_r 85,000 Proteolytic Fragment

Sunitha R. Kumari, Hilda Mendoza-Alvarez, and Rafael Alvarez-Gonzalez
Cancer Res 1998 58: 5075-5078. [Abstract] [PDF]  

Characterization of Alkaline Phosphatase Genes Expressed in Seminoma by cDNA Cloning

Atsuko Shigenari, Asako Ando, Tamami Baba, Tateki Yamamoto, Yoji Katsuoka, and Hidetoshi Inoko
Cancer Res 1998 58: 5079-5082. [Abstract] [PDF]  

Biochemistry and Biophysics:

Lactate Turnover in Rat Glioma Measured by in Vivo Nuclear Magnetic Resonance Spectroscopy

Melissa Terpstra, Rolf Gruetter, Wanda B. High, Marlene Mescher, Lance DelaBarre, Hellmut Merkle, and Michael Garwood
Cancer Res 1998 58: 5083-5088. [Abstract] [PDF]  

Carcinogenesis:

Reversion of the Neoplastic Phenotype of Human Glioblastoma Cells by Connexin 43 (cx43)

Ruo-Pan Huang, Yan Fan, Mohammad Z. Hossain, Ao Peng, Zi-Li Zeng, and Alton L. Boynton
Cancer Res 1998 58: 5089-5096. [Abstract] [PDF]  

Harvey ras Results in a Higher Frequency of Mammary Carcinomas than Kirsten ras after Direct Retroviral Transfer into the Rat Mammary Gland

Todd A. Thompson, Kwanghee Kim, and Michael N. Gould
Cancer Res 1998 58: 5097-5104. [Abstract] [PDF]  

Endocrinology:

Testing the Gonadal Regression-Cytoprotection Hypothesis

Bronwyn A. L. Crawford, Jenny A. Spaliviero, Julie M. Simpson, and David J. Handelsman
Cancer Res 1998 58: 5105-5109. [Abstract] [PDF]  

Estrogen Receptor Expression Activates the Transcriptional and Growth-inhibitory Response to Retinoids without Enhanced Retinoic Acid Receptor Expression

Angelika Rosenauer, Clara Nervi, Kelly Davison, William W. Lamph, Sylvie Mader, and Wilson H. Miller, Jr.
Cancer Res 1998 58: 5110-5116. [Abstract] [PDF]  

Epidemiology and Prevention:

A Prospective Study of Physical Activity and Prostate Cancer in Male Health Professionals

Edward Giovannucci, Michael Leitzmann, Donna Spiegelman, Eric B. Rimm, Graham A. Colditz, Meir J. Stampfer, and Walter C. Willett
Cancer Res 1998 58: 5117-5122. [Abstract] [PDF]  

NH₂-terminally Truncated HER-2/neu Protein: Relationship with Shedding of the Extracellular Domain and with Prognostic Factors in Breast Cancer

Tracy A. Christianson, Joni K. Doherty, Yuzhong J. Lin, Elizabeth E. Ramsey, Ron Holmes, Edward J. Keenan, and Gail M. Clinton
Cancer Res 1998 58: 5123-5129. [Abstract] [PDF]  

Characterization of Vincristine Transport by the M_r 190,000 Multidrug Resistance Protein (MRP): Evidence for Cotransport with Reduced Glutathione

Douglas W. Loe, Roger G. Deeley, and Susan P. C. Cole
Cancer Res 1998 58: 5130-5136. [Abstract] [PDF]  

Biliary Excretion Mechanism of CPT-11 and Its Metabolites in Humans: Involvement of Primary Active Transporters

Xiao-Yan Chu, Yukio Kato, Kaoru Ueda, Hiroshi Suzuki, Kayoko Niinuma, Charles A. Tyson, Valorie Weizer, Jack E. Dabbs, Ritchie Froehlich, Carol E. Green, and Yuichi Sugiyama
Cancer Res 1998 58: 5137-5143. [Abstract] [PDF]  

Immunology:

The Peptide Recognized by HLA-A68.2-restricted, Squamous Cell Carcinoma of the Lung-specific Cytotoxic T Lymphocytes Is Derived from a Mutated Elongation Factor 2 Gene

Kevin T. Hogan, Dominic P. Eisinger, Samuel B. Cupp, III, Kristen J. Lekstrom, Donna D. Deacon, Jeffrey Shabanowitz, Donald F. Hunt, Victor H. Engelhard, Craig L. Slingluff, Jr., and Mark M. Ross
Cancer Res 1998 58: 5144-5150. [Abstract] [PDF]  

The Anti-MUC1 Monoclonal Antibody BCP8 Can Be Used to Isolate and Identify Putative Major Histocompatibility Complex Class I Associated Amino Acid Sequences

Babita Agrawal, Mark A. Reddish, Brenda Christian, Anneke VanHeele, Leon Tang, R. Rao Koganty, and B. Michael Longenecker
Cancer Res 1998 58: 5151-5156. [Abstract] [PDF]  

Molecular Biology and Genetics:

c-Met Autocrine Activation Induces Development of Malignant Melanoma and Acquisition of the Metastatic Phenotype

Toshiyuki Otsuka, Hisashi Takayama, Richard Sharp, Giulia Celli, William J. LaRochelle, Donald P. Bottaro, Nelson Ellmore, Wilfred Vieira, Jennie W. Owens, Miriam Anver, and Glenn Merlino
Cancer Res 1998 58: 5157-5167. [Abstract] [PDF]  

c-Myb Down-Regulation Is Associated with Human Colon Cell Differentiation, Apoptosis, and Decreased Bcl-2 Expression

M. Anne Thompson, Mark A. Rosenthal, Sarah L. Ellis, Annabel J. Friend, Michelle I. Zorbas, Robert H. Whitehead, and Robert G. Ramsay
Cancer Res 1998 58: 5168-5175. [Abstract] [PDF]  

Identification of a Brain-specific APC Homologue, APCL, and Its Interaction with ß-Catenin

Hidewaki Nakagawa, Yoji Murata, Kumiko Koyama, Asao Fujiyama, Yasuo Miyoshi, Morito Monden, Tetsu Akiyama, and Yusuke Nakamura
Cancer Res 1998 58: 5176-5181. [Abstract] [PDF]  

Frequent Aberration of FHIT Gene Expression in Acute Leukemias

Toshiki Iwai, Shouhei Yokota, Makoto Nakao, Naozo Nakazawa, Masafumi Taniwaki, Takayuki Kimura, Yoshiaki Sonoda, Hiroto Kaneko, Tsukasa Okuda, Hiroshi Azuma, Toshiaki Oka, Takeo Takeda, Arata Watanabe, Atsushi Kikuta, Keiko Asami, Isao Sekine, Takeji Matsushita, Takayoshi Tsuchiya, Junichi Mimaya, Shoichi Koizumi, Shigeru Ohta, Munenori Miyake, Yoichi Takaue, Asayuki Iwai, Kenichi Nishikawa, Kazuhiro Matsumoto, Kiyoshi Kawakami, Nobuyuki Hyakuna, and Takeo Fujimoto
Cancer Res 1998 58: 5182-5187. [Abstract] [PDF]  

Failure to Complement Abnormal Phenotypes of Simian Virus 40-transformed Werner Syndrome Cells by Introduction of a Normal Human Chromosome 8

Seiji Kodama, Genro Kashino, Keiji Suzuki, Toshihiro Takatsuji, Yutaka Okumura, Mitsuo Oshimura, Masami Watanabe, and J. Carl Barrett
Cancer Res 1998 58: 5188-5195. [Abstract] [PDF]  

Nucleotide Excision Repair of Melphalan Monoadducts

David F. Grant, Tadayoshi Bessho, and Joyce T. Reardon
Cancer Res 1998 58: 5196-5200. [Abstract] [PDF]  

Identification and Characterization of Murine Caspase-14, a New Member of the Caspase Family

Manzoor Ahmad, Srinivasa M. Srinivasula, Ramesh Hegde, Rula Mukattash, Teresa Fernandes-Alnemri, and Emad S. Alnemri
Cancer Res 1998 58: 5201-5205. [Abstract] [PDF]  

Tumor Biology:

Distinct Roles of Osteopontin in Host Defense Activity and Tumor Survival during Squamous Cell Carcinoma Progression in Vivo

Howard C. Crawford, Lynn M. Matrisian, and Lucy Liaw
Cancer Res 1998 58: 5206-5215. [Abstract] [PDF]  

X-Ray-induced P-selectin Localization to the Lumen of Tumor Blood Vessels

Dennis E. Hallahan, Mary Jane Staba-Hogan, Subbu Virudachalam, and Alexander Kolchinsky
Cancer Res 1998 58: 5216-5220. [Abstract] [PDF]  

Role of the Plasminogen Activator and Matrix Metalloproteinase Systems in Epidermal Growth Factor- and Scatter Factor-stimulated Invasion of Carcinoma Cells

Eben L. Rosenthal, Timothy M. Johnson, Edward D. Allen, Ingrid J. Apel, Antonello Punturieri, and Stephen J. Weiss
Cancer Res 1998 58: 5221-5230. [Abstract] [PDF]  

Inhibition of Murine Bladder Tumorigenesis by Soy Isoflavones via Alterations in the Cell Cycle, Apoptosis, and Angiogenesis

Jin-Rong Zhou, Purna Mukherjee, Eric T. Gugger, Toshihide Tanaka, George L. Blackburn, and Steven K. Clinton
Cancer Res 1998 58: 5231-5238. [Abstract] [PDF]  

The Presence of a Constitutively Active Phosphoinositide 3-Kinase in Small Cell Lung Cancer Cells Mediates Anchorage-independent Proliferation via a Protein Kinase B and p70^s6k-dependent Pathway

Sarah M. Moore, Robert C. Rintoul, Trevor R. Walker, Edwin R. Chilvers, Christopher Haslett, and Tariq Sethi
Cancer Res 1998 58: 5239-5247. [Abstract] [PDF]  

Meeting Report:

A National Cancer Institute Workshop on Microsatellite Instability for Cancer Detection and Familial Predisposition: Development of International Criteria for the Determination of Microsatellite Instability in Colorectal Cancer

C. Richard Boland, Stephen N. Thibodeau, Stanley R. Hamilton, David Sidransky, James R. Eshleman, Randall W. Burt, Stephen J. Meltzer, Miguel A. Rodriguez-Bigas, Riccardo Fodde, G. Nadia Ranzani, and Sudhir Srivastava
Cancer Res 1998 58: 5248-5257. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1998 58: 5258-5260. [PDF]  

Erratum

Cancer Res 1998 58: 5260 [PDF]  

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