Advances in Brief:

Angiogenesis in the Hollow Fiber Tumor Model Influences Drug Delivery to Tumor Cells: Implications for Anticancer Drug Screening Programs

Roger M. Phillips, Jennifer Pearce, Paul M. Loadman, Michael C. Bibby, Patricia A. Cooper, David J. Swaine, and John A. Double
Cancer Res 1998 58: 5263-5266. [Abstract] [PDF]  

Pathogenesis of Adenocarcinoma in Peutz-Jeghers Syndrome

Stephen B. Gruber, Mark M. Entius, Gloria M. Petersen, Steven J. Laken, Patti A. Longo, Rebecca Boyer, Albert M. Levin, Urvi J. Mujumdar, Jeffrey M. Trent, Kenneth W. Kinzler, Bert Vogelstein, Stanley R. Hamilton, Mihael H. Polymeropoulos, G. Johan Offerhaus, and Francis M. Giardiello
Cancer Res 1998 58: 5267-5270. [Abstract] [PDF]  

Propagation of Genetically Altered Tumor Cells Derived from Fine-Needle Aspirates of Primary Breast Carcinoma

Zheng Li, Valerie Bustos, Joshua Miner, Eileen Paulo, Zhen Hang Meng, Galina Zlotnikov, Britt-Marie Ljung, and Shanaz H. Dairkee
Cancer Res 1998 58: 5271-5274. [Abstract] [PDF]  

Induction of Brain Tumors in Mice Using a Recombinant Platelet-derived Growth Factor B-Chain Retrovirus

Lene Uhrbom, Göran Hesselager, Monica Nistér, and Bengt Westermark
Cancer Res 1998 58: 5275-5279. [Abstract] [PDF]  

Increased Expression of Hypoxia Inducible Factor-1 in Rat and Human Prostate Cancer

Hua Zhong, Faton Agani, Angelo A. Baccala, Erik Laughner, Natalia Rioseco-Camacho, William B. Isaacs, Jonathan W. Simons, and Gregg L. Semenza
Cancer Res 1998 58: 5280-5284. [Abstract] [PDF]  

Adenoviral Transgene Expression of MMAC/PTEN in Human Glioma Cells Inhibits Akt Activation and Induces Anoikis

Michael A. Davies, Yiling Lu, Tetsuro Sano, Xianjun Fang, Ping Tang, Ruth LaPushin, Dimpy Koul, Robert Bookstein, David Stokoe, W. K. Alfred Yung, Gordon B. Mills, and Peter A. Steck
Cancer Res 1998 58: 5285-5290. [Abstract] [PDF]  

Association between Lung Cancer and Microsomal Epoxide Hydrolase Genotypes

Simone Benhamou, Maria Reinikainen, Christine Bouchardy, Pierre Dayer, and Ari Hirvonen
Cancer Res 1998 58: 5291-5293. [Abstract] [PDF]  

The Bisphosphonate Incadronate (YM175) Causes Apoptosis of Human Myeloma Cells in Vitro by Inhibiting the Mevalonate Pathway

Claire M. Shipman, Peter I. Croucher, R. Graham, G. Russell, Miep H. Helfrich, and Michael J. Rogers
Cancer Res 1998 58: 5294-5297. [Abstract] [PDF]  

Absence of Topoisomerase IIß in an Amsacrine-resistant Human Leukemia Cell Line with Mutant Topoisomerase II

Cynthia E. Herzog, Katherine A. Holmes, Laura M. Tuschong, Ram Ganapathi, and Leonard A. Zwelling
Cancer Res 1998 58: 5298-5300. [Abstract] [PDF]  

Realization of the Therapeutic Potential of CTLA-4 Blockade in Low-Dose Chemotherapy-treated Tumor-bearing Mice

Margalit B. Mokyr, Tatiana Kalinichenko, Leonid Gorelik, and Jeffrey A. Bluestone
Cancer Res 1998 58: 5301-5304. [Abstract] [PDF]  

Generation of CD8⁺ and CD4⁺ T-Cell Response to Dendritic Cells Genetically Engineered to Express the MART-1/Melan-A Gene

Ainhoa Pérez-Díez, Lisa H. Butterfield, Li Li, Nitya G. Chakraborty, James S. Economou, and Bijay Mukherji
Cancer Res 1998 58: 5305-5309. [Abstract] [PDF]  

Methylation of the Androgen Receptor Promoter CpG Island Is Associated with Loss of Androgen Receptor Expression in Prostate Cancer Cells

David F. Jarrard, Hidefumi Kinoshita, Yan Shi, Carol Sandefur, Douglas Hoff, Lorraine F. Meisner, Chawnshang Chang, James G. Herman, William B. Isaacs, and Nadine Nassif
Cancer Res 1998 58: 5310-5314. [Abstract] [PDF]  

IAP-Family Protein Survivin Inhibits Caspase Activity and Apoptosis Induced by Fas (CD95), Bax, Caspases, and Anticancer Drugs

Ingo Tamm, Yan Wang, Ed Sausville, Dominic A. Scudiero, Nicole Vigna, Tilman Oltersdorf, and John C. Reed
Cancer Res 1998 58: 5315-5320. [Abstract] [PDF]  

A Single Nucleotide Polymorphism in the Matrix Metalloproteinase-1 Promoter Creates an Ets Binding Site and Augments Transcription

Joni L. Rutter, Teresa I. Mitchell, Giovanna Butticè, Jennifer Meyers, James F. Gusella, Laurie J. Ozelius, and Constance E. Brinckerhoff
Cancer Res 1998 58: 5321-5325. [Abstract] [PDF]  

An Improved Method for Construction of Directionally Cloned cDNA Libraries from Microdissected Cells

Lisa A. Peterson, Monica R. Brown, Alex J. Carlisle, Elise C. Kohn, Lance A. Liotta, Michael R. Emmert-Buck, and David B. Krizman
Cancer Res 1998 58: 5326-5328. [Abstract] [PDF]  

Genetic Alterations of the Transforming Growth Factor ß Receptor Genes in Pancreatic and Biliary Adenocarcinomas

Michael Goggins, Manu Shekher, Kenan Turnacioglu, Charles J. Yeo, Ralph H. Hruban, and Scott E. Kern
Cancer Res 1998 58: 5329-5332. [Abstract] [PDF]  

Inactivation of the p53 Tumor Suppressor Gene via a Novel Alu Rearrangement

Robbert J. C. Slebos, Michael A. Resnick, and Jack A. Taylor
Cancer Res 1998 58: 5333-5336. [Abstract] [PDF]  

A Human Placenta-specific ATP-Binding Cassette Gene (ABCP) on Chromosome 4q22 That Is Involved in Multidrug Resistance

Rando Allikmets, Lynn M. Schriml, Amy Hutchinson, Vincenzo Romano-Spica, and Michael Dean
Cancer Res 1998 58: 5337-5339. [Abstract] [PDF]  

Catalytic Efficiencies of Allelic Variants of Human Glutathione S-transferase P1-1 toward Carcinogenic anti-Diol Epoxides of Benzo[c]phenanthrene and Benzo[g]chrysene

Xun Hu, Hong Xia, Sanjay K. Srivastava, Ajai Pal, Yogesh C. Awasthi, Piotr Zimniak, and Shivendra V. Singh
Cancer Res 1998 58: 5340-5343. [Abstract] [PDF]  

Absent or Low Expression of the Chain in T Cells at the Tumor Site Correlates with Poor Survival in Patients with Oral Carcinoma

Torsten E. Reichert, Roger Day, Eva M. Wagner, and Theresa L. Whiteside
Cancer Res 1998 58: 5344-5347. [Abstract] [PDF]  

Presence and Location of TP53 Mutation Determines Pattern of CDKN2A/ARF Pathway Inactivation in Bladder Cancer

Isabel D. C. Markl and Peter A. Jones
Cancer Res 1998 58: 5348-5353. [Abstract] [PDF]  

Carcinogenesis:

Prevention of NNK-induced Lung Tumorigenesis in A/J Mice by Acetylsalicylic Acid and NS-398

Nathalie Rioux and Andre Castonguay
Cancer Res 1998 58: 5354-5360. [Abstract] [PDF]  

The Augmentation of Melanocytic Nevi in Guinea Pigs by Solar-simulated Light: An Animal Model for Human Melanocytic Nevi

Scott Menzies, Mamdouh Khalil, Kerry Crotty, and Antonio Bonin
Cancer Res 1998 58: 5361-5366. [Abstract] [PDF]  

Differential Expression of Estrogen Receptor- and -ß Messenger RNAs as a Potential Marker of Ovarian Carcinogenesis

Pascal Pujol, Jean-Marc Rey, Philippe Nirde, Pascal Roger, Marguerite Gastaldi, François Laffargue, Henri Rochefort, and Thierry Maudelonde
Cancer Res 1998 58: 5367-5373. [Abstract] [PDF]  

Clinical Investigations:

Protection of Metabolic and Exercise Capacity in Unselected Weight-losing Cancer Patients following Treatment with Recombinant Erythropoietin: A Randomized Prospective Study

Peter Daneryd, Elisabeth Svanberg, Ulla Körner, Elisabeth Lindholm, Rolf Sandström, Hans Brevinge, Cecilia Pettersson, Ingvar Bosaeus, and Kent Lundholm
Cancer Res 1998 58: 5374-5379. [Abstract] [PDF]  

Epidemiology and Prevention:

-Difluoromethylornithine Inhibits N-Nitrosomethylbenzylamine-induced Esophageal Carcinogenesis in Zinc-deficient Rats: Effects on Esophageal Cell Proliferation and Apoptosis

Louise Y. Y. Fong, Anthony E. Pegg, and Peter N. Magee
Cancer Res 1998 58: 5380-5388. [Abstract] [PDF]  

Experimental Therapeutics:

3-(Iodoacetamido)-benzoylurea: A Novel Cancericidal Tubulin Ligand that Inhibits Microtubule Polymerization, Phosphorylates bcl-2, and Induces Apoptosis in Tumor Cells

Jian-Dong Jiang, Ashley S. Davis, Kim Middleton, Yi-He Ling, Roman Perez-Soler, James F. Holland, and J. George Bekesi
Cancer Res 1998 58: 5389-5395. [Abstract] [PDF]  

Drug Resistance Patterns of Human Neuroblastoma Cell Lines Derived from Patients at Different Phases of Therapy

Nino Keshelava, Robert C. Seeger, Susan Groshen, and C. Patrick Reynolds
Cancer Res 1998 58: 5396-5405. [Abstract] [PDF]  

Attenuation of Telomerase Activity by a Hammerhead Ribozyme Targeting the Template Region of Telomerase RNA in Endometrial Carcinoma Cells

Yasuhiro Yokoyama, Yuichiro Takahashi, Ariyoshi Shinohara, Zenglin Lian, Xiaoyun Wan, Kenji Niwa, and Teruhiko Tamaya
Cancer Res 1998 58: 5406-5410. [Abstract] [PDF]  

(E)-2'-Deoxy-2'-(fluoromethylene) Cytidine Potentiates Radioresponse of Two Human Solid Tumor Xenografts

Lin-Quan Sun, Ye-Xiong Li, Louis Guillou, and Philippe A. Coucke
Cancer Res 1998 58: 5411-5417. [Abstract] [PDF]  

Expression, Characterization, and Detection of Human Uridine Phosphorylase and Identification of Variant Uridine Phosphorolytic Activity in Selected Human Tumors

Mengping Liu, Deliang Cao, Rosalind Russell, Robert E. Handschumacher, and Giuseppe Pizzorno
Cancer Res 1998 58: 5418-5424. [Abstract] [PDF]  

Photodynamic Therapy of Orthotopic Prostate Cancer with Benzoporphyrin Derivative: Local Control and Distant Metastasis

Tetsuo Momma, Michael R. Hamblin, Horace C. Wu, and Tayyaba Hasan
Cancer Res 1998 58: 5425-5431. [Abstract] [PDF]  

Inhibition of Insulin-like Growth Factor I Receptor Expression in Neuroblastoma Cells Induces the Regression of Established Tumors in Mice

Xiangdang Liu, Thomas Turbyville, Anne Fritz, and Luke Whitesell
Cancer Res 1998 58: 5432-5438. [Abstract] [PDF]  

Immunology:

EblacZ Tumor Dormancy in Bone Marrow and Lymph Nodes: Active Control of Proliferating Tumor Cells by CD8⁺ Immune T Cells

Markus Müller, Fotini Gounari, Sophia Prifti, Hans Jörg Hacker, Volker Schirrmacher, and Khashayarsha Khazaie
Cancer Res 1998 58: 5439-5446. [Abstract] [PDF]  

Immunity to p53 Induced by an Idiotypic Network of Anti-p53 Antibodies: Generation of Sequence-specific Anti-DNA Antibodies and Protection from Tumor Metastasis

Neta Erez-Alon, Johannes Herkel, Roland Wolkowicz, Pedro J. Ruiz, Ari Waisman, Varda Rotter, and Irun R. Cohen
Cancer Res 1998 58: 5447-5452. [Abstract] [PDF]  

Molecular Biology and Genetics:

The Relationships between p53-dependent Apoptosis, Inhibition of Proliferation, and 5-Fluorouracil-induced Histopathology in Murine Intestinal Epithelia

D. Mark Pritchard, Christopher S. Potten, and John A. Hickman
Cancer Res 1998 58: 5453-5465. [Abstract] [PDF]  

Expression of AP-2 Transcription Factors in Human Breast Cancer Correlates with the Regulation of Multiple Growth Factor Signalling Pathways

Bruce C. Turner, Jian Zhang, Andrew A. Gumbs, Mary G. Maher, Leni Kaplan, Darryl Carter, Peter M. Glazer, Helen C. Hurst, Bruce G. Haffty, and Trevor Williams
Cancer Res 1998 58: 5466-5472. [Abstract] [PDF]  

Reduced COX-2 Protein in Colorectal Cancer with Defective Mismatch Repair

William E. Karnes, Jr., Rebecca Shattuck-Brandt, Lawrence J. Burgart, Raymond N. DuBois, David J. Tester, Julie M. Cunningham, Cheong-Yong Kim, Shannon K. McDonnell, Daniel J. Schaid, and Stephen N. Thibodeau
Cancer Res 1998 58: 5473-5477. [Abstract] [PDF]  

Clinicopathological Significance of Fhit Protein Expression in Stage I Non-Small Cell Lung Carcinoma

Yoshio Tomizawa, Takashi Nakajima, Takashi Kohno, Ryusei Saito, Naohito Yamaguchi, and Jun Yokota
Cancer Res 1998 58: 5478-5483. [Abstract] [PDF]  

Nuclear Factor B Dominant Negative Genetic Constructs Inhibit X-ray Induction of Cell Adhesion Molecules in the Vascular Endothelium

Dennis E. Hallahan, Subbulakshmi Virudachalam, and Jaya Kuchibhotla
Cancer Res 1998 58: 5484-5488. [Abstract] [PDF]  

Aging and DNA Methylation in Colorectal Mucosa and Cancer

Nita Ahuja, Qing Li, Avinash L. Mohan, Stephen B. Baylin, and Jean-Pierre J. Issa
Cancer Res 1998 58: 5489-5494. [Abstract] [PDF]  

Tumor Biology:

Heat Shock Protein 27 Enhances the Tumorigenicity of Immunogenic Rat Colon Carcinoma Cell Clones

Carmen Garrido, Annie Fromentin, Bernard Bonnotte, Nathalie Favre, Monique Moutet, André-Patrick Arrigo, Patrick Mehlen, and Eric Solary
Cancer Res 1998 58: 5495-5499. [Abstract] [PDF]  

The Matrix Metalloproteinase Matrilysin Influences Early-Stage Mammary Tumorigenesis

Laura A. Rudolph-Owen, Richard Chan, William J. Muller, and Lynn M. Matrisian
Cancer Res 1998 58: 5500-5506. [Abstract] [PDF]  

Abundance of Heat Shock Proteins (hsp89, hsp60, and hsp27) in Malignant Cells of Hodgkin's Disease

Pei-Ling Hsu and Su-Ming Hsu
Cancer Res 1998 58: 5507-5513. [Abstract] [PDF]  

Generation of Hepatocytes from Oval Cell Precursors in Culture

Catherine A. Lázaro, Jonathan A. Rhim, Yasuhiro Yamada, and Nelson Fausto
Cancer Res 1998 58: 5514-5522. [Abstract] [PDF]  

The RET/PTC3 Oncogene: Metastatic Solid-Type Papillary Carcinomas in Murine Thyroids

Daniel J. Powell, Jr., John Russell, Ken-ichi Nibu, Guoqi Li, Ed Rhee, Mickey Liao, Michael Goldstein, William M. Keane, Massimo Santoro, Alfredo Fusco, and Jay L. Rothstein
Cancer Res 1998 58: 5523-5528. [Abstract] [PDF]  

SPARC/Osteonectin Induces Matrix Metalloproteinase 2 Activation in Human Breast Cancer Cell Lines

Christine Gilles, James A. Bassuk, Helena Pulyaeva, E. Helene Sage, Jean-Michel Foidart, and Erik W. Thompson
Cancer Res 1998 58: 5529-5536. [Abstract] [PDF]  

Association of the Decreased Expression of 3ß1 Integrin with the Altered Cell: Environmental Interactions and Enhanced Soft Agar Cloning Ability of c-myc-overexpressing Small Cell Lung Cancer Cells

Linda F. Barr, Susan E. Campbell, Bruce S. Bochner, and Chi V. Dang
Cancer Res 1998 58: 5537-5545. [Abstract] [PDF]  

Mucin Gene Expression in Ovarian Cancers

Robert L. Giuntoli, II, Gustavo C. Rodriguez, Regina S. Whitaker, Richard Dodge, and Judith A. Voynow
Cancer Res 1998 58: 5546-5550. [Abstract] [PDF]  

Retinoic Acid and Interferon Act Synergistically as Antiangiogenic and Antitumor Agents against Human Head and Neck Squamous Cell Carcinoma

Mark W. Lingen, Peter J. Polverini, and Noël P. Bouck
Cancer Res 1998 58: 5551-5558. [Abstract] [PDF]  

Prognostic Value of ß1,6-Branched Oligosaccharides in Human Colorectal Carcinoma

Walter K. F. Seelentag, Wei-Ping Li, Shu-Fang Hsu Schmitz, Urs Metzger, Peter Aeberhard, Philipp U. Heitz, and Jürgen Roth
Cancer Res 1998 58: 5559-5564. [Abstract] [PDF]  

Vascular Endothelial Growth Factor Inhibits Apoptotic Death in Hematopoietic Cells after Exposure to Chemotherapeutic Drugs by Inducing MCL1 Acting as an Antiapoptotic Factor

Osamu Katoh, Toshiaki Takahashi, Tetsuya Oguri, Ken Kuramoto, Keiichiro Mihara, Masao Kobayashi, Shitau Hirata, and Hiromitsu Watanabe
Cancer Res 1998 58: 5565-5569. [Abstract] [PDF]  

Bcl-2-mediated Resistance to Apoptosis Is Associated with Glutathione-induced Inhibition of AP24 Activation of Nuclear DNA Fragmentation

Susan C. Wright, Hong Wang, Qi Sheng Wei, David H. Kinder, and James W. Larrick
Cancer Res 1998 58: 5570-5576. [Abstract] [PDF]  

MUC1 Synthetic Peptide Inhibition of Intercellular Adhesion Molecule-1 and MUC1 Binding Requires Six Tandem Repeats

Janice L. Kam, Lyle H. Regimbald, Joseph H. M. Hilgers, Pat Hoffman, Mark J. Krantz, B. Michael Longenecker, and Judith C. Hugh
Cancer Res 1998 58: 5577-5581. [Abstract] [PDF]  

MUC1 Is A Novel Marker for the Type II Pneumocyte Lineage during Lung Carcinogenesis

Julia A. Jarrard, R. Ilona Linnoila, HyeRan Lee, Seth M. Steinberg, Hanspeter Witschi, and Eva Szabo
Cancer Res 1998 58: 5582-5589. [Abstract] [PDF]  

Research Task Force Report:

Report from THE MARCH Research Task Force: Commissioned by THE MARCH—Coming Together to Conquer Cancer September 25–26, 1998

Ellen V. Sigal and Anna D. Barker
Cancer Res 1998 58: 5590-5627. [PDF]  

Articles:

Announcements

Cancer Res 1998 58: 5628-5629. [PDF]  

Erratum

Cancer Res 1998 58: 5630 [PDF]  

Announcement:

Recent Death

Cancer Res 1998 58: 5629 [PDF]  

Announcements:

Calendar of Events

Cancer Res 1998 58: 5629-5630. [PDF]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.