Advances in Brief:

1,N²-Propanodeoxyguanosine Adducts: Potential New Biomarkers of Smoking-induced DNA Damage in Human Oral Tissue

Raghu G. Nath, Joseph E. Ocando, Joseph B. Guttenplan, and Fung-Lung Chung
Cancer Res 1998 58: 581-584. [Abstract] [PDF]  

Cytochrome P450c17 Gene (CYP17) Polymorphism Is Associated with Serum Estrogen and Progesterone Concentrations

Heather Spencer Feigelson, Lisa S. Shames, Malcolm C. Pike, Gerhard A. Coetzee, Frank Z. Stanczyk, and Brian E. Henderson
Cancer Res 1998 58: 585-587. [Abstract] [PDF]  

An Inverse Relation between cagA⁺ Strains of Helicobacter pylori Infection and Risk of Esophageal and Gastric Cardia Adenocarcinoma

Wong-Ho Chow, Martin J. Blaser, William J. Blot, Marilie D. Gammon, Thomas L. Vaughan, Harvey A. Risch, Guillermo I. Perez-Perez, Janet B. Schoenberg, Janet L. Stanford, Heidi Rotterdam, A. Brian West, and Joseph F. Fraumeni,, Jr.
Cancer Res 1998 58: 588-590. [Abstract] [PDF]  

Hypermethylation Can Selectively Silence Individual p16^ink4A Alleles in Neoplasia

Sanna K. Myöhänen, Stephen B. Baylin, and James G. Herman
Cancer Res 1998 58: 591-593. [Abstract] [PDF]  

Close Correlation between Mutations of E2F4 and hMSH3 Genes in Colorectal Cancers with Microsatellite Instability

Masahiko Ikeda, Hideo Orimo, Hiroki Moriyama, Eiitsu Nakajima, Nagahide Matsubara, Ryuichi Mibu, Noriaki Tanaka, Takashi Shimada, Akinori Kimura, and Kenji Shimizu
Cancer Res 1998 58: 594-598. [Abstract] [PDF]  

Human Fibroblasts Expressing the Human Papillomavirus E6 Gene Are Deficient in Global Genomic Nucleotide Excision Repair and Sensitive to Ultraviolet Irradiation

James M. Ford, Elinor L. Baron, and Philip C. Hanawalt
Cancer Res 1998 58: 599-603. [Abstract] [PDF]  

Nonconservative Amino Acid Substitution Variants Exist at Polymorphic Frequency in DNA Repair Genes in Healthy Humans

M. Richard Shen, Irene M. Jones, and Harvey Mohrenweiser
Cancer Res 1998 58: 604-608. [Abstract] [PDF]  

Short Alternative Splice Transcripts of the mdm2 Oncogene Correlate to Malignancy in Human Astrocytic Neoplasms

Ryoji Matsumoto, Mitsuhiro Tada, Michimasa Nozaki, Chang-Liang Zhang, Yutaka Sawamura, and Hiroshi Abe
Cancer Res 1998 58: 609-613. [Abstract] [PDF]  

BCNU Is a Caspase-mediated Inhibitor of Drug-induced Apoptosis

István Peták, Rudolf Mihalik, Pál I. Bauer, Helga Süli-Vargha, Anna Sebestyén, and László Kopper
Cancer Res 1998 58: 614-618. [Abstract] [PDF]  

Telomerase Activity in Prostate Cancer, Prostatic Intraepithelial Neoplasia, and Benign Prostatic Epithelium

Weiben Zhang, Linda R. Kapusta, Joyce M. Slingerland, and Laurence H. Klotz
Cancer Res 1998 58: 619-621. [Abstract] [PDF]  

Expression Profile of the Putative Catalytic Subunit of the Telomerase Gene

Shyam Ramakrishnan, Urs Eppenberger, Heinz Mueller, Youichi Shinkai, and Ramaswamy Narayanan
Cancer Res 1998 58: 622-625. [Abstract] [PDF]  

Characterization of MAST9/Hevin, a SPARC-like Protein, That is Down-Regulated in Non-Small Cell Lung Cancer

Igor Bendik, Peter Schraml, and Christian U. Ludwig
Cancer Res 1998 58: 626-629. [Abstract] [PDF]  

Differences in Latency and Inducibility of Mouse Skin Melanomas Depending on the Age and Anatomic Site of the Skin

Willys K. Silvers and Beatrice Mintz
Cancer Res 1998 58: 630-632. [Abstract] [PDF]  

Biochemistry and Biophysics:

1,25-Dihydroxyvitamin D₃ Protects Human Leukemic Cells from Tumor Necrosis Factor-induced Apoptosis via Inactivation of Cytosolic Phospholipase A₂

Yu-Ling Wu, Xu-Rong Jiang, Deborah M. Lillington, Paul D. Allen, Adrian C. Newland, and Stephen M. Kelsey
Cancer Res 1998 58: 633-640. [Abstract] [PDF]  

Carcinogenesis:

Strand Specificity and Absence of Hot Spots for p53 Mutations in Ultraviolet B-induced Skin Tumors of XPA-deficient Mice

Seiji Takeuchi, Yoshimichi Nakatsu, Hironobu Nakane, Hiroaki Murai, Seiichi Hirota, Yukihiko Kitamura, Akihiko Okuyama, and Kiyoji Tanaka
Cancer Res 1998 58: 641-646. [Abstract] [PDF]  

-Hydroxytamoxifen Is a Substrate of Hydroxysteroid (Alcohol) Sulfotransferase, Resulting in Tamoxifen DNA Adducts

Shinya Shibutani, Lakkaraju Dasaradhi, Isamu Terashima, Erden Banoglu, and Michael W. Duffel
Cancer Res 1998 58: 647-653. [Abstract] [PDF]  

Endocrinology:

Consumption of a High-Fat Diet Alters Estrogen Receptor Content, Protein Kinase C Activity, and Mammary Gland Morphology in Virgin and Pregnant Mice and Female Offspring

Leena Hilakivi-Clarke, Adriana Stoica, Margarita Raygada, and MaryBeth Martin
Cancer Res 1998 58: 654-660. [Abstract] [PDF]  

Epidemiology and Prevention:

Plasma Tocopherol and Prevalence of Colorectal Adenomas in a Multiethnic Population

Sue Ann Ingles, Cristy L. Bird, James M. Shikany, Harold D. Frankl, Eric R. Lee, and Robert W. Haile
Cancer Res 1998 58: 661-666. [Abstract] [PDF]  

Cigarette Smoking, Cytochrome P450 1A1 Polymorphisms, and Breast Cancer Risk in the Nurses' Health Study

Naoko Ishibe, Susan E. Hankinson, Graham A. Colditz, Donna Spiegelman, Walter C. Willett, Frank E. Speizer, Karl T. Kelsey, and David J. Hunter
Cancer Res 1998 58: 667-671. [Abstract] [PDF]  

Experimental Therapeutics:

Pharmacokinetics of Interstitial Delivery of Carmustine, 4-Hydroperoxycyclophosphamide, and Paclitaxel from a Biodegradable Polymer Implant in the Monkey Brain

Lawrence K. Fung, Matthew G. Ewend, Allen Sills, Eric P. Sipos, Reid Thompson, Mark Watts, O. Michael Colvin, Henry Brem, and W. Mark Saltzman
Cancer Res 1998 58: 672-684. [Abstract] [PDF]  

Positive Correlation between the Efficacy of Capecitabine and Doxifluridine and the Ratio of Thymidine Phosphorylase to Dihydropyrimidine Dehydrogenase Activities in Tumors in Human Cancer Xenografts

Tohru Ishikawa, Fumiko Sekiguchi, Yu Fukase, Noriaki Sawada, and Hideo Ishitsuka
Cancer Res 1998 58: 685-690. [Abstract] [PDF]  

Cancer Dormancy: Role of Cyclin-dependent Kinase Inhibitors in Induction of Cell Cycle Arrest Mediated via Membrane IgM

Radu Marches, Richard H. Scheuermann, and Jonathan W. Uhr
Cancer Res 1998 58: 691-697. [Abstract] [PDF]  

Independent Pathways of p53 Induction by Cisplatin and X-Rays in a Cisplatin-resistant Ovarian Tumor Cell Line

Zahid H. Siddik, Betsy Mims, Guillermina Lozano, and Gerald Thai
Cancer Res 1998 58: 698-703. [Abstract] [PDF]  

Inhibition of Cyclin D1 Expression and Phosphorylation of Retinoblastoma Protein by Phosmidosine, a Nucleotide Antibiotic

Hideaki Kakeya, Rie Onose, Phillip C.-C. Liu, Chizuko Onozawa, Fumio Matsumura, and Hiroyuki Osada
Cancer Res 1998 58: 704-710. [Abstract] [PDF]  

Inhibitory Effects of Perillyl Alcohol on UVB-induced Murine Skin Cancer and AP-1 Transactivation

Margaret Barthelman, Weixing Chen, Helen L. Gensler, Chuanshu Huang, Zigang Dong, and G. Tim Bowden
Cancer Res 1998 58: 711-716. [Abstract] [PDF]  

Immunology:

Novel Triterpenoids Suppress Inducible Nitric Oxide Synthase (iNOS) and Inducible Cyclooxygenase (COX-2) in Mouse Macrophages

Najoo Suh, Tadashi Honda, Heather J. Finlay, Aaron Barchowsky, Charlotte Williams, Nicole E. Benoit, Qiao-wen Xie, Carl Nathan, Gordon W. Gribble, and Michael B. Sporn
Cancer Res 1998 58: 717-723. [Abstract] [PDF]  

Immunization with Human Papillomavirus Type 16 (HPV16) Oncoprotein-loaded Dendritic Cells as well as Protein in Adjuvant Induces MHC Class I-restricted Protection to HPV16-induced Tumor Cells

Marloes L. H. De Bruijn, Danita H. Schuurhuis, Michel P. M. Vierboom, Hans Vermeulen, Karin A. J. de Cock, Marlies E. Ooms, Maaike E. Ressing, Mireille Toebes, Kees L. M. C. Franken, Jan-Wouter Drijfhout, Tom H. M. Ottenhoff, Rienk Offringa, and Cornelis J. M. Melief
Cancer Res 1998 58: 724-731. [Abstract] [PDF]  

Her-2/neu-derived Peptides Are Tumor-associated Antigens Expressed by Human Renal Cell and Colon Carcinoma Lines and Are Recognized by in Vitro Induced Specific Cytotoxic T Lymphocytes

Peter Brossart, Gernot Stuhler, Thomas Flad, Stefan Stevanovic, Hans-Georg Rammensee, Lothar Kanz, and Wolfram Brugger
Cancer Res 1998 58: 732-736. [Abstract] [PDF]  

HLA Class I Antigen and Transporter Associated with Antigen Processing (TAP1 and TAP2) Down-Regulation in High-Grade Primary Breast Carcinoma Lesions

Marco Vitale, Rita Rezzani, Luigi Rodella, Giorgio Zauli, Piergiovanni Grigolato, Moris Cadei, Daniel J. Hicklin, and Soldano Ferrone
Cancer Res 1998 58: 737-742. [Abstract] [PDF]  

Molecular Biology and Genetics:

Identification of a New MAGE Gene with Tumor-specific Expression by Representational Difference Analysis

Sophie Lucas, Charles De Smet, Karen C. Arden, Carrie S. Viars, Bernard Lethé, Christophe Lurquin, and Thierry Boon
Cancer Res 1998 58: 743-752. [Abstract] [PDF]  

KAI1 Is Unchanged in Metastatic and Nonmetastatic Esophageal and Gastric Cancers

Xiao-Zhong Guo, Helmut Friess, Christoph Maurer, Pascal Berberat, Wen-Hao Tang, Arthur Zimmermann, Markus Naef, Hans U. Graber, Murray Korc, and Markus W. Büchler
Cancer Res 1998 58: 753-758. [Abstract] [PDF]  

A Molecular Cytogenetic Analysis of 7q31 in Prostate Cancer

Robert B. Jenkins, Junqi Qian, Hyun K. Lee, Haojie Huang, Kiyoshi Hirasawa, David G. Bostwick, John Proffitt, Kim Wilber, Michael M. Lieber, Wanguo Liu, and David I. Smith
Cancer Res 1998 58: 759-766. [Abstract] [PDF]  

Defective Expression of the DNA Mismatch Repair Protein, MLH1, Alters G₂-M Cell Cycle Checkpoint Arrest following Ionizing Radiation

Thomas W. Davis, Carmell Wilson-Van Patten, Mark Meyers, Keith A. Kunugi, Scott Cuthill, Catherine Reznikoff, Christopher Garces, C. Richard Boland, Timothy J. Kinsella, Richard Fishel, and David A. Boothman
Cancer Res 1998 58: 767-778. [Abstract] [PDF]  

Polysialic Acid on the Neural Cell Adhesion Molecule Correlates with Expression of Polysialyltransferases and Promotes Neuroblastoma Cell Growth

Herbert Hildebrandt, Christoph Becker, Sylvia Glüer, Harald Rösner, Rita Gerardy-Schahn, and Hinrich Rahmann
Cancer Res 1998 58: 779-784. [Abstract] [PDF]  

p53 Mutations in Mammary Ductal Carcinoma in Situ but not in Epithelial Hyperplasias

Susan J. Done, Nona C. R. Arneson, Hilmi Özçelik, Mark Redston, and Irene L. Andrulis
Cancer Res 1998 58: 785-789. [Abstract] [PDF]  

Detection of Unique ALL1 (MLL) Fusion Transcripts in Normal Human Bone Marrow and Blood: Distinct Origin of Normal versus Leukemic ALL1 Fusion Transcripts

Guido Marcucci, Matthew P. Strout, Clara D. Bloomfield, and Michael A. Caligiuri
Cancer Res 1998 58: 790-793. [Abstract] [PDF]  

Tumor Biology:

Expression of Granulocyte Colony-stimulating Factor Receptor Correlates with Prognosis in Oral and Mesopharyngeal Carcinoma

Hideaki Tsuzuki, Shigeharu Fujieda, Hiroshi Sunaga, Ichiro Noda, and Hitoshi Saito
Cancer Res 1998 58: 794-800. [Abstract] [PDF]  

Impairment of Survival Factor Function Potentiates Chemotherapy-induced Apoptosis in Tumor Cells

Gábor M. Lamm and Gerhard Christofori
Cancer Res 1998 58: 801-807. [Abstract] [PDF]  

Inhibition of Basic Fibroblast Growth Factor Expression, Angiogenesis, and Growth of Human Bladder Carcinoma in Mice by Systemic Interferon- Administration

Colin P. N. Dinney, Diane R. Bielenberg, Paul Perrotte, Reuven Reich, Beryl Y. Eve, Corazon D. Bucana, and Isaiah J. Fidler
Cancer Res 1998 58: 808-814. [Abstract] [PDF]  

herg Encodes a K⁺ Current Highly Conserved in Tumors of Different Histogenesis: A Selective Advantage for Cancer Cells?

Laura Bianchi, Barbara Wible, Annarosa Arcangeli, Maurizio Taglialatela, Ferdinando Morra, Pasqualina Castaldo, Olivia Crociani, Barbara Rosati, Laura Faravelli, Massimo Olivotto, and Enzo Wanke
Cancer Res 1998 58: 815-822. [Abstract] [PDF]  

Thymosin ß-10 Gene Overexpression Correlated with the Highly Malignant Neoplastic Phenotype of Transformed Thyroid Cells in Vivo and in Vitro

Daniela Califano, Carmen Monaco, Giovanni Santelli, Ada Giuliano, Maria Luisa Veronese, Maria Teresa Berlingieri, Vittorio de Franciscis, Nicole Berger, Francesco Trapasso, Massimo Santoro, Giuseppe Viglietto, and Alfredo Fusco
Cancer Res 1998 58: 823-828. [Abstract] [PDF]  

Human Papillomavirus 16 E6 Variants Are More Prevalent in Invasive Cervical Carcinoma than the Prototype

Ingeborg Zehbe, Erik Wilander, Hajo Delius, and Massimo Tommasino
Cancer Res 1998 58: 829-833. [Abstract] [PDF]  

Inhibition of Caspases by Cytokine Response Modifier A Blocks Androgen Ablation-mediated Prostate Cancer Cell Death in Vivo

Sampathkumar Srikanth and Andrew S. Kraft
Cancer Res 1998 58: 834-839. [Abstract] [PDF]  

Human Malignant Mesothelioma Cell Growth: Activation of Janus Kinase 2 and Signal Transducer and Activator of Transcription 1 for Inhibition by Interferon-

Annie Buard, Claire Vivo, Isabelle Monnet, Christian Boutin, Yannick Pilatte, and Marie-Claude Jaurand
Cancer Res 1998 58: 840-847. [Abstract] [PDF]  

A Test of the Role of 5 Integrin/Fibronectin Interactions in Tumorigenesis

Daniela Taverna, Mollie Ullman-Culleré, Helen Rayburn, Roderick T. Bronson, and Richard O. Hynes
Cancer Res 1998 58: 848-853. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1998 58: 854-856. [PDF]  

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