Advances in Brief:

Enhanced Intestinal Adenomatous Polyp Formation in Pms2^-/-;Min Mice

Sean M. Baker, Allie C. Harris, Jen-Lan Tsao, Tom J. Flath, C. Eric Bronner, Melissa Gordon, Darryl Shibata, and R. Michael Liskay
Cancer Res 1998 58: 1087-1089. [Abstract] [PDF]  

Elevated and Absent pRb Expression Is Associated with Bladder Cancer Progression and Has Cooperative Effects with p53

Richard J. Cote, Matthew D. Dunn, Sunanda J. Chatterjee, John P. Stein, Shan-Rong Shi, Quoc-Chau Tran, Shi Xue Hu, Hong Ji Xu, Susan Groshen, Clive R. Taylor, Donald G. Skinner, and William F. Benedict
Cancer Res 1998 58: 1090-1094. [Abstract] [PDF]  

T-Loop Deletion of CDC2 from Breast Cancer Tissues Eliminates Binding to Cyclin B1 and Cyclin-dependent Kinase Inhibitor p21

Tomohiko Ohta, Kazuki Okamoto, Fumihide Isohashi, Kiyotaka Shibata, Mamoru Fukuda, Susumu Yamaguchi, and Yue Xiong
Cancer Res 1998 58: 1095-1098. [Abstract] [PDF]  

Heparan/Chondroitin/Dermatan Sulfate Primer 2-(6-Hydroxynaphthyl)-O-ß-D-Xylopyranoside Preferentially Inhibits Growth of Transformed Cells

Katrin Mani, Birgitta Havsmark, Susanne Persson, Yuji Kaneda, Hisao Yamamoto, Katsukiyo Sakurai, Satoko Ashikari, Hiroko Habuchi, Sakaru Suzuki, Koji Kimata, Anders Malmström, Gunilla Westergren-Thorsson, and Lars-Åke Fransson
Cancer Res 1998 58: 1099-1104. [Abstract] [PDF]  

Frequent p53 Mutations at Dipyrimidine Sites in Patients with Pyothorax-associated Lymphoma

Tadashi Hongyo, Masayuki Kurooka, Eiji Taniguchi, Keiji Iuchi, Yutsuki Nakajima, Katsuyuki Aozasa, and Taisei Nomura
Cancer Res 1998 58: 1105-1107. [Abstract] [PDF]  

Expression of CD44 Variant Exon 6 in Stage I Non-Small Cell Lung Carcinoma as a Prognostic Factor

Toshiki Hirata, Tatsuo Fukuse, Hironobu Naiki, Shigeki Hitomi, and Hiromi Wada
Cancer Res 1998 58: 1108-1110. [Abstract] [PDF]  

Eleutherobin, a Novel Cytotoxic Agent That Induces Tubulin Polymerization, Is Similar to Paclitaxel (Taxol®)

Byron H. Long, Joan M. Carboni, Arthur J. Wasserman, Laurie A. Cornell, Anna Maria Casazza, Paul R. Jensen, Thomas Lindel, William Fenical, and Craig R. Fairchild
Cancer Res 1998 58: 1111-1115. [Abstract] [PDF]  

An Anti-CD30 Chimeric Receptor That Mediates CD3--independent T-Cell Activation against Hodgkin's Lymphoma Cells in the Presence of Soluble CD30

Andreas Hombach, Claudia Heuser, Ranjan Sircar, Thorsten Tillmann, Volker Diehl, Christoph Pohl, and Hinrich Abken
Cancer Res 1998 58: 1116-1119. [Abstract] [PDF]  

BRCA1 Up-Regulation Is Associated with Repair-mediated Resistance to cis-Diamminedichloroplatinum(II)

Amreen Husain, Guoshun He, Ennapadam S. Venkatraman, and David R. Spriggs
Cancer Res 1998 58: 1120-1123. [Abstract] [PDF]  

Mutations of the DPC4/Smad4 Gene in Biliary Tract Carcinoma

Stephan A. Hahn, Detlef Bartsch, Anja Schroers, Hamid Galehdari, Matthias Becker, Annette Ramaswamy, Irmgard Schwarte-Waldhoff, Hansjörg Maschek, and Wolff Schmiegel
Cancer Res 1998 58: 1124-1126. [Abstract] [PDF]  

High Frequency of ß-Catenin (Ctnnb1) Mutations in the Colon Tumors Induced by Two Heterocyclic Amines in the F344 Rat

Roderick H. Dashwood, Masumi Suzui, Hitoshi Nakagama, Takashi Sugimura, and Minako Nagao
Cancer Res 1998 58: 1127-1129. [Abstract] [PDF]  

Mutational Analysis of the APC/ß-Catenin/Tcf Pathway in Colorectal Cancer

Andrew B. Sparks, Patrice J. Morin, Bert Vogelstein, and Kenneth W. Kinzler
Cancer Res 1998 58: 1130-1134. [Abstract] [PDF]  

Inhibition of the p38 Mitogen-activated Protein Kinase by SB 203580 Blocks PMA-induced M_r 92,000 Type IV Collagenase Secretion and in Vitro Invasion

Christian Simon, Helmuth Goepfert, and Douglas Boyd
Cancer Res 1998 58: 1135-1139. [Abstract] [PDF]  

A Distinct Region of Chromosome 19p13.3 Associated with the Sporadic Form of Adenoma Malignum of the Uterine Cervix

Jung Young Lee, Seung Myung Dong, Hy Sook Kim, Su Young Kim, Eun Young Na, Min Sun Shin, Sug Hyung Lee, Won Sang Park, Kyoung Mee Kim, Youn Soo Lee, Ja June Jang, and Nam Jin Yoo
Cancer Res 1998 58: 1140-1143. [Abstract] [PDF]  

Biochemistry and Biophysics:

Participation of Iron and Nitric Oxide in the Mutagenicity of Asbestos in hgprt^-, gpt⁺ Chinese Hamster V79 Cells

Sun-Hee Park and Ann E. Aust
Cancer Res 1998 58: 1144-1148. [Abstract] [PDF]  

Clinical Investigations:

Ki-ras Mutation and p53 Overexpression Predict the Clinical Behavior of Colorectal Cancer: A Southwest Oncology Group Study

Dennis J. Ahnen, Polly Feigl, Gang Quan, Cecelia Fenoglio-Preiser, Laura C. Lovato, Paul A. Bunn, Jr., Grant Stemmerman, John D. Wells, John S. Macdonald, and Frank L. Meyskens, Jr.
Cancer Res 1998 58: 1149-1158. [Abstract] [PDF]  

Endocrinology:

Elevated Insulin-like Growth Factor I Receptor Autophosphorylation and Kinase Activity in Human Breast Cancer

Jamie L. Resnik, Donna B. Reichart, Kim Huey, Nicholas J. G. Webster, and B. Lynn Seely
Cancer Res 1998 58: 1159-1164. [Abstract] [PDF]  

Experimental Therapeutics:

The Antiproliferative Activity of DMDC Is Modulated by Inhibition of Cytidine Deaminase

Hiroyuki Eda, Masako Ura, Kaori F.-Ouchi, Yutaka Tanaka, Masanori Miwa, and Hideo Ishitsuka
Cancer Res 1998 58: 1165-1169. [Abstract] [PDF]  

Intracellular Expression of an Antibody Fragment-neutralizing p21 Ras Promotes Tumor Regression

Olivier Cochet, Mireille Kenigsberg, Isabelle Delumeau, Angela Virone-Oddos, Marie-Christine Multon, Wolf Herman Fridman, Fabien Schweighoffer, Jean-Luc Teillaud, and Bruno Tocqué
Cancer Res 1998 58: 1170-1176. [Abstract] [PDF]  

Low Potency of Taxol at Microtubule Minus Ends: Implications for its Antimitotic and Therapeutic Mechanism

W. Brent Derry, Leslie Wilson, and Mary Ann Jordan
Cancer Res 1998 58: 1177-1184. [Abstract] [PDF]  

Carbogen Breathing Increases 5-Fluorouracil Uptake and Cytotoxicity in Hypoxic Murine RIF-1 Tumors: A Magnetic Resonance Study in Vivo

Paul M. J. McSheehy, Simon P. Robinson, Agatha S. E. Ojugo, Eric O. Aboagye, Mark B. Cannell, Martin O. Leach, Ian R. Judson, and John R. Griffiths
Cancer Res 1998 58: 1185-1194. [Abstract] [PDF]  

Elucidation of the Mechanism Enabling Tumor Selective Prodrug Monotherapy

Klaus Bosslet, Rainer Straub, Matthias Blumrich, Joerg Czech, Manfred Gerken, Bernhard Sperker, Heyo K. Kroemer, Jean-Pierre Gesson, Michel Koch, and Claude Monneret
Cancer Res 1998 58: 1195-1201. [Abstract] [PDF]  

Treatment of hepatic metastasis of the Colon26 adenocarcinoma with an -Galactosylceramide, KRN7000

Ryusuke Nakagawa, Kazuhiro Motoki, Hitomi Ueno, Rieko Iijima, Hiromi Nakamura, Eiichi Kobayashi, Akihiro Shimosaka, and Yasuhiko Koezuka
Cancer Res 1998 58: 1202-1207. [Abstract] [PDF]  

Immunology:

Non-Small Cell Lung Cancer Cyclooxygenase-2-dependent Regulation of Cytokine Balance in Lymphocytes and Macrophages: Up-Regulation of Interleukin 10 and Down-Regulation of Interleukin 12 Production

Min Huang, Marina Stolina, Sherven Sharma, Jenny T. Mao, Li Zhu, Patrice W. Miller, Jerome Wollman, Harvey Herschman, and Steven M. Dubinett
Cancer Res 1998 58: 1208-1216. [Abstract] [PDF]  

Molecular Mimicry of Carcinoembryonic Antigen by Peptides Derived from the Structure of an Anti-Idiotype Antibody

Sunil K. Chatterjee, Pulak K. Tripathi, Mala Chakraborty, John Yannelli, Haito Wang, Kenneth A. Foon, Curtis C. Maier, J. Edwin Blalock, and Malaya Bhattacharya-Chatterjee
Cancer Res 1998 58: 1217-1224. [Abstract] [PDF]  

Interleukin 12 Gene Therapy of MHC-negative Murine Melanoma Metastases

Patrizia Nanni, Ilaria Rossi, Carla De Giovanni, Lorena Landuzzi, Giordano Nicoletti, Antonella Stoppacciaro, Mariella Parenza, Mario P. Colombo, and Pier-Luigi Lollini
Cancer Res 1998 58: 1225-1230. [Abstract] [PDF]  

Molecular Biology and Genetics:

Frequent Deletion and 5' CpG Island Methylation of the p16 Gene in Primary Malignant Lymphoma of the Brain

Shu-Jing Zhang, Sumio Endo, Tomio Ichikawa, Kazuo Washiyama, and Toshiro Kumanishi
Cancer Res 1998 58: 1231-1237. [Abstract] [PDF]  

Transcription of a Novel Mouse Semaphorin Gene, M-semaH, Correlates with the Metastatic Ability of Mouse Tumor Cell Lines

Claus R. L. Christensen, Jörg Klingelhöfer, Svetlana Tarabykina, Egil F. Hulgaard, Dmitri Kramerov, and Eugene Lukanidin
Cancer Res 1998 58: 1238-1244. [Abstract] [PDF]  

The Role of DNA Methylation in Expression of the p19/p16 Locus in Human Bladder Cancer Cell Lines

Mark L. Gonzalgo, Toshiro Hayashida, Christina M. Bender, Martha M. Pao, Yvonne C. Tsai, Felicidad A. Gonzales, Hung D. Nguyen, TuDung T. Nguyen, and Peter A. Jones
Cancer Res 1998 58: 1245-1252. [Abstract] [PDF]  

Antitumor Effect of a Farnesyl Protein Transferase Inhibitor in Mammary and Lymphoid Tumors Overexpressing N-ras in Transgenic Mice

Ramon Mangues, Teresa Corral, Nancy E. Kohl, W. Fraser Symmans, Suying Lu, Marcos Malumbres, Jackson B. Gibbs, Allen Oliff, and Angel Pellicer
Cancer Res 1998 58: 1253-1259. [Abstract] [PDF]  

Mutations of the Bacteriophage T4 Type II DNA Topoisomerase That Alter Sensitivity to Antitumor Agent 4'-(9-Acridinylamino)methanesulfon-m-anisidide and an Antibacterial Quinolone

Catherine H. Freudenreich, Christine Chang, and Kenneth N. Kreuzer
Cancer Res 1998 58: 1260-1267. [Abstract] [PDF]  

Mutational Spectra of a 100-Base Pair Mitochondrial DNA Target Sequence in Bronchial Epithelial Cells: A Comparison of Smoking and Nonsmoking Twins

Hilary A. Coller, Konstantin Khrapko, Alfonso Torres, Mark W. Frampton, Mark J. Utell, and William G. Thilly
Cancer Res 1998 58: 1268-1277. [Abstract] [PDF]  

Vascular Permeability Factor/Vascular Endothelial Growth Factor-mediated Signaling In Mouse Mesentery Vascular Endothelium

Debabrata Mukhopadhyay, Janice A. Nagy, Eleanor J. Manseau, and Harold F. Dvorak
Cancer Res 1998 58: 1278-1284. [Abstract] [PDF]  

Tumor Biology:

Reduced Lysyl Oxidase Messenger RNA Levels in Experimental and Human Prostate Cancer

Chengzhen Ren, Guang Yang, Terry L. Timme, Thomas M. Wheeler, and Timothy C. Thompson
Cancer Res 1998 58: 1285-1290. [Abstract] [PDF]  

Uroplakin II Gene Is Expressed in Transitional Cell Carcinoma But Not in Bilharzial Bladder Squamous Cell Carcinoma: Alternative Pathways of Bladder Epithelial Differentiation and Tumor Formation

Ren-Long Wu, Iman Osman, Xue-Ru Wu, Ming-Lan Lu, Zuo-Feng Zhang, Feng-Xia Liang, Reda Hamza, Howard Scher, Carlos Cordon-Cardo, and Tung-Tien Sun
Cancer Res 1998 58: 1291-1297. [Abstract] [PDF]  

Molecular Mediators of Angiogenesis in Bladder Cancer

Steven C. Campbell, Olga V. Volpert, Marina Ivanovich, and Noël P. Bouck
Cancer Res 1998 58: 1298-1304. [Abstract] [PDF]  

Differential Regulation of Cyclin-dependent Kinase Inhibitors in Monolayer and Spheroid Cultures of Tumorigenic and Nontumorigenic Fibroblasts

Karen E. A. LaRue, E. Morton Bradbury, and James P. Freyer
Cancer Res 1998 58: 1305-1314. [Abstract] [PDF]  

Differential Expression of a Truncated Form of the Urokinase-type Plasminogen-Activator Receptor in Normal and Tumor Thyroid Cells

Pia Ragno, Nunzia Montuori, Bianca Covelli, Gunilla Hoyer-Hansen, and Guido Rossi
Cancer Res 1998 58: 1315-1319. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1998 58: 1320-1322. [PDF]  

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