Advances in Brief:

Frequent Abnormalities of the Putative Tumor Suppressor Gene FHIT at 3p14.2 in Pancreatic Carcinoma Cell Lines

Babette Simon, Detlef Bartsch, Peter Barth, Nicole Prasnikar, Karin Münch, Andreas Blum, Rudolf Arnold, and Burkhard Göke
Cancer Res 1998 58: 1583-1587. [Abstract] [PDF]  

Mutations at BRCA1: The Medullary Breast Carcinoma Revisited

François Eisinger, Jocelyne Jacquemier, Colette Charpin, Dominique Stoppa-Lyonnet, Brigitte Bressac-de Paillerets, Jean-Philippe Peyrat, Michel Longy, Jean-Marc Guinebretière, Richard Sauvan, Tetsuro Noguchi, Daniel Birnbaum, and Hagay Sobol
Cancer Res 1998 58: 1588-1592. [Abstract] [PDF]  

p53-dependent and -independent Regulation of the Death Receptor KILLER/DR5 Gene Expression in Response to Genotoxic Stress and Tumor Necrosis Factor

M. Saeed Sheikh, Timothy F. Burns, Ying Huang, Gen Sheng Wu, Sally Amundson, Kia S. Brooks, Albert J. Fornace, Jr., and Wafik S. El-Deiry
Cancer Res 1998 58: 1593-1598. [Abstract] [PDF]  

Lymphatic Endothelium and Kaposi's Sarcoma Spindle Cells Detected by Antibodies against the Vascular Endothelial Growth Factor Receptor-3

Lotta Jussila, Reija Valtola, Taina A. Partanen, Petri Salven, Päivi Heikkilä, Marja-Terttu Matikainen, Risto Renkonen, Arja Kaipainen, Michael Detmar, Erwin Tschachler, Riitta Alitalo, and Kari Alitalo
Cancer Res 1998 58: 1599-1604. [Abstract] [PDF]  

Benzo[a]pyrene Diol Epoxide-induced 3p21.3 Aberrations and Genetic Predisposition to Lung Cancer

Xifeng Wu, Ying Zhao, Susan E. Honn, Gail E. Tomlinson, John D. Minna, Waun Ki Hong, and Margaret R. Spitz
Cancer Res 1998 58: 1605-1608. [Abstract] [PDF]  

Serine-70 Is One of the Critical Sites for Drug-induced Bcl2 Phosphorylation in Cancer Cells

Subrata Haldar, Aruna Basu, and Carlo M. Croce
Cancer Res 1998 58: 1609-1615. [Abstract] [PDF]  

Association of Elevated Mutagenesis in the Spleen with Genetic Susceptibility to Induced Plasmacytoma Development in Mice

Klaus Felix, Kevin Kelliher, Georg-Wilhelm Bornkamm, and Siegfried Janz
Cancer Res 1998 58: 1616-1619. [Abstract] [PDF]  

Association of Prostate Cancer with Vitamin D Receptor Haplotypes in African-Americans

Sue Ann Ingles, Gerhard A. Coetzee, Ronald K. Ross, Brian E. Henderson, Lawrence N. Kolonel, Laura Crocitto, Wei Wang, and Robert W. Haile
Cancer Res 1998 58: 1620-1623. [Abstract] [PDF]  

Cathepsin L2, a Novel Human Cysteine Proteinase Produced by Breast and Colorectal Carcinomas

Iñigo Santamaría, Gloria Velasco, Maite Cazorla, Antonio Fueyo, Elías Campo, and Carlos López-Otín
Cancer Res 1998 58: 1624-1630. [Abstract] [PDF]  

Increased ß-Actin Expression in an Invasive Moloney Sarcoma Virus-transformed MDCK Cell Variant Concentrates to the Tips of Multiple Pseudopodia

Phuong U. Le, Trung N. Nguyen, Patrick Drolet-Savoie, Nicole Leclerc, and Ivan R. Nabi
Cancer Res 1998 58: 1631-1635. [Abstract] [PDF]  

High-intensity Raf Signals Convert Mitotic Cell Cycling into Cellular Growth

Eugen Kerkhoff and Ulf R. Rapp
Cancer Res 1998 58: 1636-1640. [Abstract] [PDF]  

Protein Kinase C Activation Increases Transepithelial Transport of Biologically Active Insulin

James M. Mullin, Nicole Ginanni, and Kathleen V. Laughlin
Cancer Res 1998 58: 1641-1645. [Abstract] [PDF]  

E2F1 Messenger RNA Is Destabilized in Response to a Growth Inhibitor in Normal Human Keratinocytes but not in a Squamous Carcinoma Cell Line

Nicholas A. Saunders, Anthony J. Dicker, Susan J. Jones, and Alison L. Dahler
Cancer Res 1998 58: 1646-1649. [Abstract] [PDF]  

The Mammalian Ribonucleotide Reductase R2 Component Cooperates with a Variety of Oncogenes in Mechanisms of Cellular Transformation

Huizhou Fan, Cristy Villegas, Aiping Huang, and Jim A. Wright
Cancer Res 1998 58: 1650-1653. [Abstract] [PDF]  

Carcinogenesis:

Polyamines Regulate Expression of the Neoplastic Phenotype in Mouse Skin

Alejandro Peralta Soler, Gwendolyn Gilliard, Louis Megosh, Kenneth George, and Thomas G. O'Brien
Cancer Res 1998 58: 1654-1659. [Abstract] [PDF]  

Quantitative Trait Loci Affecting 4-Nitroquinoline 1-oxide-induced Tongue Carcinogenesis in the Rat

Jun-ichi Tanuma, Hayase Shisa, Hiroshi Hiai, Shin Higashi, Yoshihiro Yamada, Toshiyuki Kamoto, Yoshikazu Hirayama, Hiroaki Matsuuchi, and Motoo Kitano
Cancer Res 1998 58: 1660-1664. [Abstract] [PDF]  

Mechanism of the Paradoxical, Inhibitory Effect of Phenobarbital on Hepatocarcinogenesis Initiated in Infant B6C3F₁ Mice with Diethylnitrosamine

Gang-Hong Lee, Takao Ooasa, and Makoto Osanai
Cancer Res 1998 58: 1665-1669. [Abstract] [PDF]  

Endocrinology:

Expression of Insulin-like Growth Factor-binding Protein 6 Complementary DNA Alters Neuroblastoma Cell Growth

Pascale Grellier, Brigitte De Galle, and Sylvie Babajko
Cancer Res 1998 58: 1670-1676. [Abstract] [PDF]  

Experimental Therapeutics:

An Apoptosis-inducing Gene Therapy for Pancreatic Cancer with a Combination of 55-kDa Tumor Necrosis Factor (TNF) Receptor Gene Transfection and Mutein TNF Administration

Tsutomu Sato, Naofumi Yamauchi, Hiroyoshi Sasaki, Minoru Takahashi, Tetsuro Okamoto, Sumio Sakamaki, Naoki Watanabe, and Yoshiro Niitsu
Cancer Res 1998 58: 1677-1683. [Abstract] [PDF]  

Enrichment of the More Hydrophilic Bile Acid Ursodeoxycholic Acid in the Fecal Water-soluble Fraction after Feeding to Rats with Colon Polyps

Ashok K. Batta, Gerald Salen, Henna Holubec, Thomas A. Brasitus, David Alberts, and David L. Earnest
Cancer Res 1998 58: 1684-1687. [Abstract] [PDF]  

Regional Pharmacokinetics of 5-Fluorouracil in Dogs: Role of the Liver, Gastrointestinal Tract, and Lungs

Han-Yi Kuan, David E. Smith, William D. Ensminger, James A. Knol, Susan J. DeRemer, Zhaomin Yang, and Philip L. Stetson
Cancer Res 1998 58: 1688-1694. [Abstract] [PDF]  

Interleukin 15 Protects against Toxicity and Potentiates Antitumor Activity of 5-Fluorouracil Alone and in Combination with Leucovorin in Rats Bearing Colorectal Cancer

Shousong Cao, Anthony B. Troutt, and Youcef M. Rustum
Cancer Res 1998 58: 1695-1699. [Abstract] [PDF]  

Immunology:

Differential T Helper Cell Responses to Human Papillomavirus Type 16 E7 Related to Viral Clearance or Persistence in Patients with Cervical Neoplasia: A Longitudinal Study

Tanja D. de Gruijl, Hetty J. Bontkes, Jan M. M. Walboomers, Marij J. Stukart, Fania S. Doekhie, Ans J. Remmink, Theo J. M. Helmerhorst, René H. M. Verheijen, Margaret F. Duggan-Keen, Peter L. Stern, Chris J. L. M. Meijer, and Rik J. Scheper
Cancer Res 1998 58: 1700-1706. [Abstract] [PDF]  

Molecular Biology and Genetics:

Allelotyping of Endometriosis with Adjacent Ovarian Carcinoma Reveals Evidence of a Common Lineage

Xiuxian Jiang, Sarah J. Morland, Andrew Hitchcock, Eric J. Thomas, and Ian G. Campbell
Cancer Res 1998 58: 1707-1712. [Abstract] [PDF]  

Microsatellite Instability in Colorectal Cancer: Different Mutator Phenotypes and the Principal Involvement of hMLH1

Stephen N. Thibodeau, Amy J. French, Julie M. Cunningham, David Tester, Lawrence J. Burgart, Patrick C. Roche, Shannon K. McDonnell, Daniel J. Schaid, Catherine Walsh Vockley, Virginia V. Michels, Gist H. Farr, Jr., and Michael J. O'Connell
Cancer Res 1998 58: 1713-1718. [Abstract] [PDF]  

Two North American Families with Hereditary Papillary Renal Carcinoma and Identical Novel Mutations in the MET Proto-Oncogene

Laura Schmidt, Kerstin Junker, Gregor Weirich, Gladys Glenn, Peter Choyke, Irina Lubensky, Zhengping Zhuang, Michael Jeffers, George Vande Woude, Hartmutt Neumann, McClellan Walther, W. Marston Linehan, and Berton Zbar
Cancer Res 1998 58: 1719-1722. [Abstract] [PDF]  

Antioxidant Action via p53-mediated Apoptosis

Ming Liu, Jill C. Pelling, Jingfang Ju, Edward Chu, and Douglas E. Brash
Cancer Res 1998 58: 1723-1729. [Abstract] [PDF]  

Loss or Altered Subcellular Localization of p27 in Barrett's Associated Adenocarcinoma

Surendra P. Singh, Jennifer Lipman, Harvey Goldman, F. Henry Ellis, Jr., Laura Aizenman, M. Giulia Cangi, Sabina Signoretti, Dah S. Chiaur, Michele Pagano, and Massimo Loda
Cancer Res 1998 58: 1730-1735. [Abstract] [PDF]  

Molecular Cytogenetic Analysis in Splenic Lymphoma with Villous Lymphocytes: Frequent Allelic Imbalance of the RB1 Gene but not the D13S25 Locus on Chromosome 13q14

José A. García-Marco, Amara Nouel, Blanca Navarro, Estella Matutes, David Oscier, Cathy M. Price, and Daniel Catovsky
Cancer Res 1998 58: 1736-1740. [Abstract] [PDF]  

Tumor Biology:

Human Pancreatic Adenocarcinomas Express Fas and Fas Ligand Yet Are Resistant to Fas-mediated Apoptosis

Hendrik Ungefroren, Martina Voss, Martina Jansen, Christian Roeder, Doris Henne-Bruns, Bernd Kremer, and Holger Kalthoff
Cancer Res 1998 58: 1741-1749. [Abstract] [PDF]  

Size-dependent Increase in Prostanoid Levels in Adenomas of Patients with Familial Adenomatous Polyposis

Vincent W. Yang, Janiel M. Shields, Stanley R. Hamilton, Ernst W. Spannhake, Walter C. Hubbard, Linda M. Hylind, C. Rahj Robinson, and Francis M. Giardiello
Cancer Res 1998 58: 1750-1753. [Abstract] [PDF]  

Inhibiting Ras Prenylation Increases the Radiosensitivity of Human Tumor Cell Lines with Activating Mutations of ras Oncogenes

Eric J. Bernhard, W. Gillies McKenna, Andrew D. Hamilton, Said M. Sebti, Yimin Qian, JunMin Wu, and Ruth J. Muschel
Cancer Res 1998 58: 1754-1761. [Abstract] [PDF]  

cdc25 Cell Cycle-activating Phosphatases and c-myc Expression in Human Non-Hodgkin's Lymphomas

Silvia Hernández, Luis Hernández, Sílvia Beà, Maite Cazorla, Pedro L. Fernández, Alfons Nadal, Jaume Muntané, Carme Mallofré, Emilio Montserrat, Antonio Cardesa, and Elías Campo
Cancer Res 1998 58: 1762-1767. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1998 58: 1768-1770. [PDF]  

Correction

Irwin H. Gelman
Cancer Res 1998 58: 1770 [PDF]  

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