Advances in Brief:

Quantitation of MYC Gene Expression in Sporadic Breast Tumors with a Real-Time Reverse Transcription-PCR Assay

Ivan Bièche, Ingrid Laurendeau, Sengül Tozlu, Martine Olivi, Dominique Vidaud, Rosette Lidereau, and Michel Vidaud
Cancer Res 1999 59: 2759-2765. [Abstract] [Full Text] [PDF]  

Inhibitors of Histone Deacetylase Relieve ETO-mediated Repression and Induce Differentiation of AML1-ETO Leukemia Cells

Jianxiang Wang, Yogen Saunthararajah, Robert L. Redner, and Johnson M. Liu
Cancer Res 1999 59: 2766-2769. [Abstract] [Full Text] [PDF]  

Molecular Cloning and Functional Analysis of the Mouse Homologue of the KILLER/DR5 Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Death Receptor

Gen Sheng Wu, Timothy F. Burns, Yi Zhan, Emad S. Alnemri, and Wafik S. El-Deiry
Cancer Res 1999 59: 2770-2775. [Abstract] [Full Text] [PDF]  

Recurrent Involvement of 2p23 in Inflammatory Myofibroblastic Tumors

Constance A. Griffin, Anita L. Hawkins, Cecily Dvorak, Carol Henkle, Tara Ellingham, and Elizabeth J. Perlman
Cancer Res 1999 59: 2776-2780. [Abstract] [Full Text] [PDF]  

The Transcriptional Activities of p53 and Its Homologue p51/p63: Similaritiesand Differences

Akira Shimada, Shunsuke Kato, Kentaro Enjo, Motonobu Osada, Yoji Ikawa, Kenji Kohno, Masuo Obinata, Ryunosuke Kanamaru, Shuntaro Ikawa, and Chikashi Ishioka
Cancer Res 1999 59: 2781-2786. [Abstract] [Full Text] [PDF]  

Human Prostate Cancer Expresses the Low Affinity Insulin-like Growth Factor Binding Protein IGFBP-rP1

Armelle Degeorges, Fuan Wang, Henry F. Frierson, Jr., Arun Seth, Leland W. K. Chung, and Robert A. Sikes
Cancer Res 1999 59: 2787-2790. [Abstract] [Full Text] [PDF]  

Elevated and Biallelic Expression of p73 Is Associated with Progression of Human Bladder Cancer

Sung-Gil Chi, Sung-Goo Chang, Sun-Ju Lee, Choong-Hyun Lee, Jin Il Kim, and Jae-Hoon Park
Cancer Res 1999 59: 2791-2793. [Abstract] [Full Text] [PDF]  

Prognostic Significance of Polo-like Kinase (PLK) Expression in Squamous Cell Carcinomas of the Head and Neck

Rainald Knecht, Robert Elez, Martin Oechler, Christine Solbach, Christoph von Ilberg, and Klaus Strebhardt
Cancer Res 1999 59: 2794-2797. [Abstract] [Full Text] [PDF]  

Eponemycin Exerts Its Antitumor Effect through the Inhibition of Proteasome Function

Lihao Meng, Benjamin H. B. Kwok, Ny Sin, and Craig M. Crews
Cancer Res 1999 59: 2798-2801. [Abstract] [Full Text] [PDF]  

Adoptive Transfer of Immature Dendritic Cells with Autologous or Allogeneic Tumor Cells Generates Systemic Antitumor Immunity

Alan Melcher, Stephen Todryk, Andrew Bateman, Heung Chong, Nicholas R Lemoine, and Richard G Vile
Cancer Res 1999 59: 2802-2805. [Abstract] [Full Text] [PDF]  

Identification of a Region of Frequent Loss of Heterozygosity at 11q24 in Colorectal Cancer

Kate C. Connolly, Hani Gabra, Christopher J. Millwater, Karen J. Taylor, Genevieve J. Rabiasz, J. E. Vivienne Watson, John F. Smyth, Andrew H. Wyllie, and Duncan I. Jodrell
Cancer Res 1999 59: 2806-2809. [Abstract] [Full Text] [PDF]  

Identification of a Transactivation Activity in the COOH-Terminal Region of p73 Which Is Impaired in the Naturally Occurring Mutants Found inHuman Neuroblastomas

Naoyuki Takada, Toshinori Ozaki, Shingo Ichimiya, Satoru Todo, and Akira Nakagawara
Cancer Res 1999 59: 2810-2814. [Abstract] [Full Text] [PDF]  

Activation of Mitochondrial Raf-1 Is Involved in the Antiapoptotic Effects of Akt

Miroslaw Majewski, Malgorzata Nieborowska-Skorska, Paolo Salomoni, Artur Slupianek, Krzysztof Reiss, Rossana Trotta, Bruno Calabretta, and Tomasz Skorski
Cancer Res 1999 59: 2815-2819. [Abstract] [Full Text] [PDF]  

Molecular Cloning and Expression of an Alternative hKLK3 Transcript Coding for a Variant Protein of Prostate-specific Antigen

Nathalie Heuzé, Sophie Olayat, Ninette Gutman, Marie-Louise Zani, and Yves Courty
Cancer Res 1999 59: 2820-2824. [Abstract] [Full Text] [PDF]  

CYP17 and Breast Cancer Risk: The Polymorphism in the 5' Flanking Area of the Gene Does Not Influence Binding to Sp-1

Vessela Nedelcheva Kristensen, Ellen K. Haraldsen, Kristin B. Anderson, P. E. Lønning, Bjørn Erikstein, Rolf Kåresen, Odd S. Gabrielsen, and Anne-Lise Børresen-Dale
Cancer Res 1999 59: 2825-2828. [Abstract] [Full Text] [PDF]  

Implication of p53 in Growth Arrest and Apoptosis Induced by the Synthetic Retinoid CD437 in Human Lung Cancer Cells

Shi-Yong Sun, Ping Yue, Gen Sheng Wu, Wafik S. El-Deiry, Braham Shroot, Waun K. Hong, and Reuben Lotan
Cancer Res 1999 59: 2829-2833. [Abstract] [Full Text] [PDF]  

Optimizing Syngeneic Orthotopic Murine Bladder Cancer (MB49)

Jan H. Günther, Andreas Jurczok, Tina Wulf, Sven Brandau, Irina Deinert, Dieter Jocham, and Andreas Böhle
Cancer Res 1999 59: 2834-2837. [Abstract] [Full Text] [PDF]  

Dead or Dying: Necrosis versus Apoptosis in Caspase-deficient Human RenalCell Carcinoma

Vladimir Kolenko, Robert G. Uzzo, Ronald Bukowski, Neil H. Bander, Andrew C. Novick, Eric D. Hsi, and James H. Finke
Cancer Res 1999 59: 2838-2842. [Abstract] [Full Text] [PDF]  

Transcriptional Up-Regulation of Paxillin Expression by Heregulin in Human Breast Cancer Cells

Ratna Vadlamudi, Liana Adam, Ben Tseng, Louis Costa, and Rakesh Kumar
Cancer Res 1999 59: 2843-2846. [Abstract] [Full Text] [PDF]  

Biochemistry:

Antagonism of p53-dependent Apoptosis by Mitogen Signals

Mira Hong, Ming-Derg Lai, Young-Sun Lin, and Ming-Zong Lai
Cancer Res 1999 59: 2847-2852. [Abstract] [Full Text] [PDF]  

Intercalation into DNA Is Not Required for Inhibition of Topoisomerase I by Indolocarbazole Antitumor Agents

Christian Bailly, Laurent Dassonneville, Pierre Colson, Claude Houssier, Kazuhiro Fukasawa, Susumu Nishimura, and Tomoko Yoshinari
Cancer Res 1999 59: 2853-2860. [Abstract] [Full Text] [PDF]  

Carcinogenesis:

Blocking Transforming Growth Factor ß Signaling in Transgenic Epidermis Accelerates Chemical Carcinogenesis: A Mechanism Associated with Increased Angiogenesis

Cindy Go, Ping Li, and Xiao-Jing Wang
Cancer Res 1999 59: 2861-2868. [Abstract] [Full Text] [PDF]  

NG2 Proteoglycan-binding Peptides Target Tumor Neovasculature

Michael A. Burg, Renata Pasqualini, Wadih Arap, Erkki Ruoslahti, and William B. Stallcup
Cancer Res 1999 59: 2869-2874. [Abstract] [Full Text] [PDF]  

Effects of Chronic Low-Dose Ultraviolet B Radiation on DNA Damage and Repair in Mouse Skin

David L. Mitchell, Rüdiger Greinert, Frank R. de Gruijl, Kees L. H. Guikers, Eckhard W. Breitbart, Michelle Byrom, Michelle M. Gallmeier, Megan G. Lowery, and Beate Volkmer
Cancer Res 1999 59: 2875-2884. [Abstract] [Full Text] [PDF]  

Clinical Investigations:

Expression of Cyclin A in Soft Tissue Sarcomas Correlates with Tumor Aggressiveness

Riikka Leena Huuhtanen, Carl Peter Blomqvist, Tom Ove Böhling, Tom Anders Wiklund, Erkki Juhani Tukiainen, Martti Virolainen, Bernhard Tribukait, and Leif Christer Andersson
Cancer Res 1999 59: 2885-2890. [Abstract] [Full Text] [PDF]  

Endocrinology:

The Phosphatidylinositol 3'-kinase Pathway Is a Dominant Growth Factor-activated Cell Survival Pathway in LNCaP Human Prostate Carcinoma Cells

Jianqing Lin, Rosalyn M. Adam, Eric Santiestevan, and Michael R. Freeman
Cancer Res 1999 59: 2891-2897. [Abstract] [Full Text] [PDF]  

N-myc Regulation of Type I Insulin-like Growth Factor Receptor in a Human Neuroblastoma Cell Line

Daniel Chambéry, Sarah Mohseni-Zadeh, Brigitte de Gallé, and Sylvie Babajko
Cancer Res 1999 59: 2898-2902. [Abstract] [Full Text] [PDF]  

Epidemiology and Prevention:

Candidate Genetic Modifiers of Individual Susceptibility to Renal Cell Carcinoma: A Study of Polymorphic Human Xenobiotic-metabolizing Enzymes

Sandrine Longuemaux, Claudine Deloménie, Catherine Gallou, Arnaud Méjean, Monique Vincent-Viry, Raymonde Bouvier, Dominique Droz, Rajagopal Krishnamoorthy, Marie-Madeleine Galteau, Claudine Junien, Christophe Béroud, and Jean-Marie Dupret
Cancer Res 1999 59: 2903-2908. [Abstract] [Full Text] [PDF]  

Experimental Therapeutics:

Carcinoembryonic Antigen (CEA)-specific T-Cell Activation in Colon Carcinoma Induced by Anti-CD3xAnti-CEA Bispecific Diabodies and B7xAnti-CEA Bispecific Fusion Proteins

Philipp Holliger, Oliver Manzke, Mary Span, Robert Hawkins, Bernd Fleischmann, Liu Qinghua, Jürgen Wolf, Volker Diehl, Olivier Cochet, Greg Winter, and Heribert Bohlen
Cancer Res 1999 59: 2909-2916. [Abstract] [Full Text] [PDF]  

Tumor Pretargeting with Avidin Improves the Therapeutic Index of Biotinylated Tumor Necrosis Factor in Mouse Models

Anna Gasparri, Monica Moro, Flavio Curnis, Angelina Sacchi, Stefano Pagano, Fabrizio Veglia, Giulia Casorati, Antonio G. Siccardi, Paolo Dellabona, and Angelo Corti
Cancer Res 1999 59: 2917-2923. [Abstract] [Full Text] [PDF]  

Differential Effects of a Stem Cell Factor-Immunoglobulin Fusion Protein on Malignant and Normal Hematopoietic Cells

Ulrike Erben, Eckhard Thiel, and Michael Notter
Cancer Res 1999 59: 2924-2930. [Abstract] [Full Text] [PDF]  

KF25706, a Novel Oxime Derivative of Radicicol, Exhibits in Vivo Antitumor Activity via Selective Depletion of Hsp90 Binding Signaling Molecules

Shiro Soga, Leonard M. Neckers, Theodor W. Schulte, Yukimasa Shiotsu, Kazuhito Akasaka, Hiroaki Narumi, Tsutomu Agatsuma, Yoji Ikuina, Chikara Murakata, Tatsuya Tamaoki, and Shiro Akinaga
Cancer Res 1999 59: 2931-2938. [Abstract] [Full Text] [PDF]  

Homocamptothecin, an E-Ring Modified Camptothecin with Enhanced Lactone Stability, Retains Topoisomerase I-targeted Activity andAntitumor Properties

Laurence Lesueur-Ginot, Danièle Demarquay, Robert Kiss, Philip G. Kasprzyk, Laurent Dassonneville, Christian Bailly, José Camara, Olivier Lavergne, and Dennis C. H. Bigg
Cancer Res 1999 59: 2939-2943. [Abstract] [Full Text] [PDF]  

Antitumor Activity of P-4055 (Elaidic Acid-Cytarabine) Compared to Cytarabine in Metastatic and s.c. Human Tumor Xenograft Models

Knut Breistøl, Jan Balzarini, Marit Liland Sandvold, Finn Myhren, Marita Martinsen, Erik De Clercq, and Øystein Fodstad
Cancer Res 1999 59: 2944-2949. [Abstract] [Full Text] [PDF]  

Immunology:

Primary Chemically Induced Tumors Induce Profound Immunosuppression Concomitant with Apoptosis and Alterations in Signal Transduction in T Cells and NK Cells

Shigetoshi Horiguchi, Max Petersson, Tsutomu Nakazawa, Minoru Kanda, Arnold H. Zea, Augusto C. Ochoa, and Rolf Kiessling
Cancer Res 1999 59: 2950-2956. [Abstract] [Full Text] [PDF]  

Molecular Biology and Genetics:

p16/pRb Pathway Alterations Are Required for Bypassing Senescence in Human Prostate Epithelial Cells

David F. Jarrard, Somdatta Sarkar, Yan Shi, Thomas R. Yeager, Gregg Magrane, Hidefumi Kinoshita, Nadine Nassif, Lorraine Meisner, Michael A. Newton, Frederic M. Waldman, and Catherine A. Reznikoff
Cancer Res 1999 59: 2957-2964. [Abstract] [Full Text] [PDF]  

Colonic Hamartoma Development by Anomalous Duplication in Cdx2Knockout Mice

Yoshitaka Tamai, Reiko Nakajima, Tomo-o Ishikawa, Kazuaki Takaku, Michael F. Seldin, and Makoto M. Taketo
Cancer Res 1999 59: 2965-2970. [Abstract] [Full Text] [PDF]  

Autocrine Interleukin-1ß Production in Leukemia: Evidence for the Involvement of Mutated RAS6

Darrin M. Beaupre, Moshe Talpaz, Frank C. Marini, III, Richard J. Cristiano, Jack A. Roth, Zeev Estrov, Maher Albitar, Melvin H. Freedman, and Razelle Kurzrock
Cancer Res 1999 59: 2971-2980. [Abstract] [Full Text] [PDF]  

Carboxypeptidase A3 (CPA3): A Novel Gene Highly Induced by Histone Deacetylase Inhibitors during Differentiation of Prostate Epithelial Cancer Cells

Haojie Huang, Christopher P. Reed, Jin-San Zhang, Viji Shridhar, Liang Wang, and David I. Smith
Cancer Res 1999 59: 2981-2988. [Abstract] [Full Text] [PDF]  

Heparin/Heparan Sulfate Interacting Protein Gene Expression Is Up-regulated in Human Colorectal Carcinoma and Correlated with Differentiation Status and Metastasis

Yuxun Wang, Denis Cheong, Steven Chan, and Shing Chuan Hooi
Cancer Res 1999 59: 2989-2994. [Abstract] [Full Text] [PDF]  

Frameshift Mutations at Mononucleotide Repeats in caspase-5 and Other Target Genes in Endometrial and Gastrointestinal Cancer of the Microsatellite Mutator Phenotype

Simó Schwartz, Jr., Hiroyuki Yamamoto, Manuel Navarro, Marisa Maestro, Jaume Reventós, and Manuel Perucho
Cancer Res 1999 59: 2995-3002. [Abstract] [Full Text] [PDF]  

Tumor Biology:

Proteomics and Immunohistochemistry Define Some of the Steps Involved in the Squamous Differentiation of the Bladder Transitional Epithelium: A Novel Strategy for Identifying Metaplastic Lesions

Julio E. Celis, Pamela Celis, Morten Østergaard, Bodil Basse, Jette B. Lauridsen, Gitte Ratz, Hanne H. Rasmussen, Torben F. Ørntoft, Bente Hein, Hans Wolf, and Ariana Celis
Cancer Res 1999 59: 3003-3009. [Abstract] [Full Text] [PDF]  

The Viral Protein Apoptin Induces Apoptosis in UV-C-irradiated Cells from Individuals with Various Hereditary Cancer-prone Syndromes

Ying-Hui Zhang, Peter J. Abrahams, Alex J. van der Eb, and Mathieu H. M. Noteborn
Cancer Res 1999 59: 3010-3015. [Abstract] [Full Text] [PDF]  

Correction:

C. Praml et al., Cancer Res., 58: 5014–5018, 1998

Cancer Res 1999 59: 3019 [Full Text] [PDF]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.