Advances in Brief:

Apoptosis Induced by Overexpression of hMSH2 or hMLH1

Hong Zhang, Burt Richards, Teresa Wilson, Michael Lloyd, Aaron Cranston, Andrew Thorburn, Richard Fishel, and Mark Meuth
Cancer Res 1999 59: 3021-3027. [Abstract] [Full Text] [PDF]  

Mammaglobin Expression in Primary, Metastatic, and Occult Breast Cancer

Mark A. Watson, Suzanne Dintzis, Christopher M. Darrow, Lora E. Voss, John DiPersio, Roy Jensen, and Timothy P. Fleming
Cancer Res 1999 59: 3028-3031. [Abstract] [Full Text] [PDF]  

Allelotype of Posterior Uveal Melanoma: Implications for a Bifurcated Tumor Progression Pathway

Paola Parrella, David Sidransky, and Shannath L. Merbs
Cancer Res 1999 59: 3032-3037. [Abstract] [Full Text] [PDF]  

N-acetyltransferase 2 Influences Cancer Prevalence in hMLH1/hMSH2 Mutation Carriers

Karl Heinimann, Rodney J. Scott, Pierre Chappuis, Walter Weber, Hansjakob Müller, Zuzana Dobbie, and Pierre Hutter
Cancer Res 1999 59: 3038-3040. [Abstract] [Full Text] [PDF]  

Clinical Implication of Expression of Platelet-derived Endothelial Cell Growth Factor (PD-ECGF) in Metastatic Lesions of Uterine Cervical Cancers

Jiro Fujimoto, Hideki Sakaguchi, Reiko Hirose, Hongwu Wen, and Teruhiko Tamaya
Cancer Res 1999 59: 3041-3044. [Abstract] [Full Text] [PDF]  

Association of the NAD(P)H:quinone Oxidoreductase ⁶⁰⁹CT Polymorphism with a Decreased Lung Cancer Risk

Hongwei Chen, Annette Lum, Ann Seifried, Lynne R. Wilkens, and Loïc Le Marchand
Cancer Res 1999 59: 3045-3048. [Abstract] [Full Text] [PDF]  

Enhanced Efficacy of Transcriptionally Targeted Suicide Gene/Prodrug Therapy for Thyroid Carcinoma with the Cre-loxP System

Yuji Nagayama, Eijun Nishihara, Makoto Iitaka, Hiroyuki Namba, Shunichi Yamashita, and Masami Niwa
Cancer Res 1999 59: 3049-3052. [Abstract] [Full Text] [PDF]  

Arsenic Induces Apoptosis through a c-Jun NH₂-Terminal Kinase-dependent, p53-independent Pathway

Chuanshu Huang, Wei-ya Ma, Jingxia Li, and Zigang Dong
Cancer Res 1999 59: 3053-3058. [Abstract] [Full Text] [PDF]  

Role of O⁶-Alkylguanine-DNA Alkyltransferase in Protecting against Cyclophosphamide-induced Toxicity and Mutagenicity

Yingna Cai, Michael H. Wu, Susan M. Ludeman, David J. Grdina, and M. Eileen Dolan
Cancer Res 1999 59: 3059-3063. [Abstract] [Full Text] [PDF]  

-Fetoprotein-specific Genetic Immunotherapy for Hepatocellular Carcinoma

Charles M. Vollmer, Jr., Fritz C. Eilber, Lisa H. Butterfield, Antoni Ribas, Vivian B. Dissette, Andrew Koh, Lara D. Montejo, Maggie C. Lee, Kahlil J. Andrews, William H. McBride, John A. Glaspy, and James S. Economou
Cancer Res 1999 59: 3064-3067. [Abstract] [Full Text] [PDF]  

Alterations of Fas (APO-1/CD95) Gene in Transitional Cell Carcinomas of Urinary Bladder

Sug Hyung Lee, Min Sun Shin, Won Sang Park, Su Young Kim, Seung Myung Dong, Jae Ho Pi, Hun Kyung Lee, Ho Sik Kim, Ja June Jang, Choo Soung Kim, Sang Ho Kim, Jung Young Lee, and Nam Jin Yoo
Cancer Res 1999 59: 3068-3072. [Abstract] [Full Text] [PDF]  

Radiation-induced Mutations at the Autosomal Thymidine Kinase Locus Are Not Elevated in p53-null Cells

Yao-Yu Eric Chuang, Qi Chen, and Howard L. Liber
Cancer Res 1999 59: 3073-3076. [Abstract] [Full Text] [PDF]  

Biochemistry:

Cisplatin-induced Apoptosis Proceeds by Caspase-3-dependent and -independent Pathways in Cisplatin-resistant and -sensitive Human Ovarian Cancer Cell Lines

Karen M. Henkels and John J. Turchi
Cancer Res 1999 59: 3077-3083. [Abstract] [Full Text] [PDF]  

Carcinogenesis:

Chemoprevention of Rat Prostate Carcinogenesis by Early and Delayed Administration of Dehydroepiandrosterone

K. V. N. Rao, William D. Johnson, Maarten C. Bosland, Ronald A. Lubet, Vernon E. Steele, Gary J. Kelloff, and David L. McCormick
Cancer Res 1999 59: 3084-3089. [Abstract] [Full Text] [PDF]  

Endocrinology:

Estrogen Receptor Activation via Activation Function 2 Predicts Agonism of Xenoestrogens in Normal and Neoplastic Cells of the Uterine Myometrium

Deborah S. Hunter, Leslie C. Hodges, Peter M. Vonier, Robin Fuchs-Young, Marco M. Gottardis, and Cheryl L. Walker
Cancer Res 1999 59: 3090-3099. [Abstract] [Full Text] [PDF]  

Experimental Therapeutics:

Use of the Glucose Starvation-inducible Glucose-regulated Protein 78 Promoter in Suicide Gene Therapy of Murine Fibrosarcoma

Gadi Gazit, Gene Hung, Xinke Chen, W. French Anderson, and Amy S. Lee
Cancer Res 1999 59: 3100-3106. [Abstract] [Full Text] [PDF]  

Fas-FasL-mediated CD4+ T-Cell Apoptosis following Stem Cell Transplantation

Rakesh K. Singh, Michelle L. Varney, Suleyman Buyukberber, Kazuhiko Ino, Ana G. Ageitos, Elizabeth Reed, Stefano Tarantolo, and James E. Talmadge
Cancer Res 1999 59: 3107-3111. [Abstract] [Full Text] [PDF]  

In Vivo Antitumor Activity of Choline Kinase Inhibitors: A Novel Target for Anticancer Drug Discovery

Rubén Hernández-Alcoceba, Félix Fernández, and Juan Carlos Lacal
Cancer Res 1999 59: 3112-3118. [Abstract] [Full Text] [PDF]  

Immunology:

GD3 Ganglioside Antibody Augments Tumoricidal Capacity of Canine Blood Mononuclear Cells by Induction of Interleukin 12

Stuart C. Helfand, Erin B. Dickerson, Keith L. Munson, and Marcia L. Padilla
Cancer Res 1999 59: 3119-3127. [Abstract] [Full Text] [PDF]  

Tumor Rejection by in Vivo Administration of Anti-CD25 (Interleukin-2 Receptor ) Monoclonal Antibody

Shozaburo Onizuka, Isao Tawara, Jun Shimizu, Shimon Sakaguchi, Teizo Fujita, and Eiichi Nakayama
Cancer Res 1999 59: 3128-3133. [Abstract] [Full Text] [PDF]  

Generation of Human T-cell Responses to an HLA-A2.1-restricted Peptide Epitope Derived from -Fetoprotein

Lisa H. Butterfield, Andrew Koh, Wilson Meng, Charles M. Vollmer, Antoni Ribas, Vivian Dissette, Eric Lee, John A. Glaspy, William H. McBride, and James S. Economou
Cancer Res 1999 59: 3134-3142. [Abstract] [Full Text] [PDF]  

Molecular Biology and Genetics:

The Cancer Antiapoptosis Mouse Survivin Gene: Characterization of Locus and Transcriptional Requirements of Basal and Cell Cycle-dependent Expression

Fengzhi Li and Dario C. Altieri
Cancer Res 1999 59: 3143-3151. [Abstract] [Full Text] [PDF]  

hSNF5/INI1 Inactivation Is Mainly Associated with Homozygous Deletions and Mitotic Recombinations in Rhabdoid Tumors

Marie-Françoise Rousseau-Merck, Isabella Versteege, Isabelle Legrand, Jérôme Couturier, Aline Mairal, Olivier Delattre, and Alain Aurias
Cancer Res 1999 59: 3152-3156. [Abstract] [Full Text] [PDF]  

Characterization of the GAGE Genes That Are Expressed in Various Human Cancers and in Normal Testis

Olivier De Backer, Karen C. Arden, Mauro Boretti, Valérie Vantomme, Charles De Smet, Suzanne Czekay, Carrie S. Viars, Etienne De Plaen, Francis Brasseur, Patrick Chomez, Benoît Van den Eynde, Thierry Boon, and Pierre van der Bruggen
Cancer Res 1999 59: 3157-3165. [Abstract] [Full Text] [PDF]  

Telomerase Activity and Human Telomerase Reverse Transcriptase mRNA Expression in Soft Tissue Tumors: Correlation with Grade, Histology, and Proliferative Activity

Pu Yan, Jean-Michel Coindre, Jean Benhattar, Fredrik T. Bosman, and Louis Guillou
Cancer Res 1999 59: 3166-3170. [Abstract] [Full Text] [PDF]  

LightCycler Technology for the Quantitation of bcr/abl Fusion Transcripts

Karl-Anton Kreuzer, Ulrich Lass, Alexander Bohn, Olfert Landt, and Christian Andreas Schmidt
Cancer Res 1999 59: 3171-3174. [Abstract] [Full Text] [PDF]  

The Human p53 Negative Regulatory Domain Mediates Inhibition of Reporter Gene Transactivation in Yeast Lacking Thioredoxin Reductase

Gary F. Merrill, Paul Dowell, and George D. Pearson
Cancer Res 1999 59: 3175-3179. [Abstract] [Full Text] [PDF]  

The SYT-SSX1 Variant of Synovial Sarcoma Is Associated with a High Rate of Tumor Cell Proliferation and Poor Clinical Outcome

Gunnar Nilsson, Björn Skytting, Yuntao Xie, Bertha Brodin, Roland Perfekt, Nils Mandahl, Joakim Lundeberg, Mathias Uhlén, and Olle Larsson
Cancer Res 1999 59: 3180-3184. [Abstract] [Full Text] [PDF]  

Tumor Biology:

Two Independent Mechanisms Essential for Tumor Angiogenesis: Inhibition of Human Melanoma Xenograft Growth by Interfering with either the Vascular Endothelial Growth Factor Receptor Pathway or the Tie-2 Pathway

Gerhard Siemeister, Michael Schirner, Karin Weindel, Petra Reusch, Andreas Menrad, Dieter Marmé, and Georg Martiny-Baron
Cancer Res 1999 59: 3185-3191. [Abstract] [Full Text] [PDF]  

Five Different Anti-Prostate-specific Membrane Antigen (PSMA) Antibodies Confirm PSMA Expression in Tumor-associated Neovasculature

Sam S. Chang, Victor E. Reuter, W. D. W. Heston, Neil H. Bander, Lana S. Grauer, and Paul B. Gaudin
Cancer Res 1999 59: 3192-3198. [Abstract] [Full Text] [PDF]  

Testisin, a New Human Serine Proteinase Expressed by Premeiotic Testicular Germ Cells and Lost in Testicular Germ Cell Tumors

John D. Hooper, David L. Nicol, Joanne L. Dickinson, Helen J. Eyre, Anthony L. Scarman, John F. Normyle, Melanie A. Stuttgen, Meaghan L. Douglas, Kate A. Lakoski Loveland, Grant R. Sutherland, and Toni M. Antalis
Cancer Res 1999 59: 3199-3205. [Abstract] [Full Text] [PDF]  

Contribution of c-erbB-2 and Topoisomerase II to Chemoresistance in Ovarian Cancer

Jan G. Hengstler, Jost Lange, Alexandra Kett, Nadja Dornhöfer, Rolf Meinert, Michael Arand, Paul G. Knapstein, Roger Becker, Franz Oesch, and Berno Tanner
Cancer Res 1999 59: 3206-3214. [Abstract] [Full Text] [PDF]  

Isolation of a Novel Gene, TSP50, by a Hypomethylated DNA Fragment in Human Breast Cancer

Liming Yuan, Jidong Shan, Dwight De Risi, John Broome, John Lovecchio, David Gal, Vincent Vinciguerra, and Hao-peng Xu
Cancer Res 1999 59: 3215-3221. [Abstract] [Full Text] [PDF]  

Progranulin Gene Expression Regulates Epithelial Cell Growth and Promotes Tumor Growth in Vivo

Zhiheng He and Andrew Bateman
Cancer Res 1999 59: 3222-3229. [Abstract] [Full Text] [PDF]  

Protein Kinase C Involvement in Mammary Tumor Cell Metastasis

Susan C. Kiley, Kimberly J. Clark, Michelle Goodnough, Danny R. Welch, and Susan Jaken
Cancer Res 1999 59: 3230-3238. [Abstract] [Full Text] [PDF]  

Nitric Oxide Is an Initiator of Intercellular Signal Transduction for Stress Response after Hyperthermia in Mutant p53 Cells of Human Glioblastoma

Hideki Matsumoto, Sachiko Hayashi, Masanori Hatashita, Ken Ohnishi, Toshio Ohtsubo, Ryuhei Kitai, Hiroki Shioura, Takeo Ohnishi, and Eiichi Kano
Cancer Res 1999 59: 3239-3244. [Abstract] [Full Text] [PDF]  

Loss of P27^Kip1 Expression Correlates with Tumor Grade and with Reduced Disease-free Survival in Primary Superficial Bladder Cancers

Alessandro Sgambato, Mario Migaldi, Beatrice Faraglia, Lorella Garagnani, Gianpiero Romano, Carmela De Gaetani, Paolo Ferrari, Giovanni Capelli, Gian Paolo Trentini, and Achille Cittadini
Cancer Res 1999 59: 3245-3250. [Abstract] [Full Text] [PDF]  

Presence of Tumor DNA in Plasma of Breast Cancer Patients: Clinicopathological Correlations

Jose M. Silva, Gemma Dominguez, Jose M. Garcia, Rocio Gonzalez, Maria J. Villanueva, Fatima Navarro, Mariano Provencio, Santiago San Martin, Pilar España, and Felix Bonilla
Cancer Res 1999 59: 3251-3256. [Abstract] [Full Text] [PDF]  

Overexpression of the Wild Type p73 Gene in Breast Cancer Tissues and Cell Lines

Alex I. Zaika, Sergey Kovalev, Natalie D. Marchenko, and Ute M. Moll
Cancer Res 1999 59: 3257-3263. [Abstract] [Full Text] [PDF]  

The Insulin-like Growth Factor 1 Receptor Induces Transformation and Tumorigenicity of Ovarian Mesothelial Cells and Down-Regulates Their Fas-Receptor Expression

Domenico Coppola, Beatrice Saunders, Ling Fu, Weiguang Mao, and Santo V. Nicosia
Cancer Res 1999 59: 3264-3270. [Abstract] [Full Text] [PDF]  

Meeting Report:

Tenth Annual Pezcoller Symposium: The Genetics of Cancer Susceptibility

Enrico Mihich, Louise Strong, and Richard Klausner
Cancer Res 1999 59: 3271 [PDF]  

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