Advances in Brief:

Gene Therapy with Dominant-negative Stat3 Suppresses Growth of the Murine Melanoma B16 Tumor in Vivo

Guilian Niu, Richard Heller, Robyn Catlett-Falcone, Domenico Coppola, Mark Jaroszeski, William Dalton, Richard Jove, and Hua Yu
Cancer Res 1999 59: 5059-5063. [Abstract] [Full Text] [PDF]  

Fusion of the EWS-related Gene TAF2N to TEC in Extraskeletal Myxoid Chondrosarcoma

Helene Sjögren, Jeanne Meis-Kindblom, Lars-Gunnar Kindblom, Pierre Åman, and Göran Stenman
Cancer Res 1999 59: 5064-5067. [Abstract] [Full Text] [PDF]  

Germ-line msh6 Mutations in Colorectal Cancer Families

Richard D. Kolodner, Jessica D. Tytell, James L. Schmeits, Michael F. Kane, Ruchira Das Gupta, John Weger, Siobhan Wahlberg, Edward A. Fox, David Peel, Argyrios Ziogas, Judy E. Garber, Sapna Syngal, Hoda Anton-Culver, and Frederick P. Li
Cancer Res 1999 59: 5068-5074. [Abstract] [Full Text] [PDF]  

MDM2 and MDMX Inhibit the Transcriptional Activity of Ectopically Expressed SMAD Proteins

Cain H. Yam, Wai Yi Siu, Talha Arooz, Clarissa H. S. Chiu, Anita Lau, Xiao Qi Wang, and Randy Y. C. Poon
Cancer Res 1999 59: 5075-5078. [Abstract] [Full Text] [PDF]  

A Novel Human Xenograft Model of Inflammatory Breast Cancer

Mary L. Alpaugh, James S. Tomlinson, Zhi-Ming Shao, and Sanford H. Barsky
Cancer Res 1999 59: 5079-5084. [Abstract] [Full Text] [PDF]  

Inhibition of Homologue of Slimb (HOS) Function Sensitizes Human Melanoma Cells for Apoptosis

Viatcheslav A. Soldatenkov, Anatoly Dritschilo, Ze’ev Ronai, and Serge Y. Fuchs
Cancer Res 1999 59: 5085-5088. [Abstract] [Full Text] [PDF]  

Compensatory Lung Growth after Partial Pneumonectomy Enhances Lung Tumorigenesis Induced by 3-Methylcholanthrene

Lynn M. Brown, Alvin M. Malkinson, D. Eugene Rannels, and Stephen R. Rannels
Cancer Res 1999 59: 5089-5092. [Abstract] [Full Text] [PDF]  

Role of the Prostaglandin E Receptor Subtype EP₁ in Colon Carcinogenesis

Kouji Watanabe, Toshihiko Kawamori, Seiichi Nakatsugi, Toshihisa Ohta, Shuichi Ohuchida, Hiroshi Yamamoto, Takayuki Maruyama, Kigen Kondo, Fumitaka Ushikubi, Shuh Narumiya, Takashi Sugimura, and Keiji Wakabayashi
Cancer Res 1999 59: 5093-5096. [Abstract] [Full Text] [PDF]  

Cell Cycle Regulation of Menin Expression

Hiroshi Kaji, Lucie Canaff, David Goltzman, and Geoffrey N. Hendy
Cancer Res 1999 59: 5097-5101. [Abstract] [Full Text] [PDF]  

Antitumor Cytotoxicity Mediated by Ligand-activated Human V24 NKT Cells

Tetsu Kawano, Toshinori Nakayama, Noriaki Kamada, Yoshikatsu Kaneko, Michishige Harada, Nobutaka Ogura, Yasunori Akutsu, Shinichiro Motohashi, Toshihiko Iizasa, Hideharu Endo, Takehiko Fujisawa, Hiroshi Shinkai, and Masaru Taniguchi
Cancer Res 1999 59: 5102-5105. [Abstract] [Full Text] [PDF]  

Comparative Studies of a Retrovirus versus a Poxvirus Vector in Whole Tumor-Cell Vaccines

James W. Hodge and Jeffrey Schlom
Cancer Res 1999 59: 5106-5111. [Abstract] [Full Text] [PDF]  

p57^KIP2 Expression and Loss of Heterozygosity during Immortal Conversion of Cultured Human Mammary Epithelial Cells

Tarlochan Nijjar, Don Wigington, James C. Garbe, Andreas Waha, Martha R. Stampfer, and Paul Yaswen
Cancer Res 1999 59: 5112-5118. [Abstract] [Full Text] [PDF]  

Classification of Small Cell Lung Cancer and Pulmonary Carcinoid by Gene Expression Profiles

Ramaswamy Anbazhagan, Tarik Tihan, Daniel M. Bornman, James C. Johnston, Joel H. Saltz, Anthony Weigering, Steven Piantadosi, and Edward Gabrielson
Cancer Res 1999 59: 5119-5122. [Abstract] [Full Text] [PDF]  

Arginine Vasopressin Promoter Regulation Is Mediated by a Neuron-restrictive Silencer Element in Small Cell Lung Cancer

Judy M. Coulson, Carolyn E. Fiskerstrand, Penella J. Woll, and John P. Quinn
Cancer Res 1999 59: 5123-5127. [Abstract] [Full Text] [PDF]  

Angiogenic Activity of Human Soluble Intercellular Adhesion Molecule-1

Yong Song Gho, Hynda K. Kleinman, and Gabriel Sosne
Cancer Res 1999 59: 5128-5132. [Abstract] [Full Text] [PDF]  

Biochemistry:

Role of Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase Cascade in Gonadotropin-releasing Hormone-induced Growth Inhibition of a Human Ovarian Cancer Cell Line

Akiko Kimura, Masahide Ohmichi, Hirohisa Kurachi, Hiromasa Ikegami, Jun Hayakawa, Keiichi Tasaka, Yuki Kanda, Yukihiro Nishio, Hiroaki Jikihara, Nariaki Matsuura, and Yuji Murata
Cancer Res 1999 59: 5133-5142. [Abstract] [Full Text] [PDF]  

Carcinogenesis:

Polyethylene-glycol Suppresses Colon Cancer and Causes Dose-dependent Regression of Azoxymethane-induced Aberrant Crypt Foci in Rats

Géraldine Parnaud, Sylviane Taché, Ginette Peiffer, and Denis E. Corpet
Cancer Res 1999 59: 5143-5147. [Abstract] [Full Text] [PDF]  

Pancolonic Chromosomal Instability Precedes Dysplasia and Cancer in Ulcerative Colitis

Peter S. Rabinovitch, Shawna Dziadon, Teresa A. Brentnall, Mary J. Emond, David A. Crispin, Rodger C. Haggitt, and Mary P. Bronner
Cancer Res 1999 59: 5148-5153. [Abstract] [Full Text] [PDF]  

N-Oxidative Metabolism of 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in Humans Excretion of the N^2-Glucuronide Conjugate of 2-Hydroxyamino-MeIQx in Urine

W. G. Stillwell, Robert J. Turesky, Rashmi Sinha, and Steven R. Tannenbaum
Cancer Res 1999 59: 5154-5159. [Abstract] [Full Text] [PDF]  

Clinical Investigations:

Induction of Immunity to Prostate Cancer Antigens: Results of a Clinical Trial of Vaccination with Irradiated Autologous Prostate Tumor Cells Engineered to Secrete Granulocyte-Macrophage Colony-stimulating Factor Using ex Vivo Gene Transfer

Jonathan W. Simons, Bahar Mikhak, Ju-Fay Chang, Angelo M. DeMarzo, Michael A. Carducci, Michael Lim, Christine E. Weber, Angelo A. Baccala, Marti A. Goemann, Shirley M. Clift, Dale G. Ando, Hyam I. Levitsky, Lawrence K. Cohen, Martin G. Sanda, Richard C. Mulligan, Alan W. Partin, H. Ballentine Carter, Steven Piantadosi, Fray F. Marshall, and William G. Nelson
Cancer Res 1999 59: 5160-5168. [Abstract] [Full Text] [PDF]  

Sensitive Detection of K-ras Mutations Augments Diagnosis of Colorectal Cancer Metastases in the Liver

Carl C. Schimanski, Ulrich Linnemann, and Martin R. Berger
Cancer Res 1999 59: 5169-5175. [Abstract] [Full Text] [PDF]  

Endocrinology:

Effects of the Antiestrogen EM-800 (SCH 57050) and Cyclophosphamide Alone and in Combination on Growth of Human ZR-75-1 Breast Cancer Xenografts in Nude Mice

Matthieu Gutman, Steeve Couillard, Fernand Labrie, Bernard Candas, and Claude Labrie
Cancer Res 1999 59: 5176-5180. [Abstract] [Full Text] [PDF]  

Epidemiology and Prevention:

Risk Factors for Ki-ras Protooncogene Mutation in Sporadic Colorectal Adenomas

María Elena Martínez, Terese Maltzman, James R. Marshall, Janine Einspahr, Mary E. Reid, Richard Sampliner, Dennis J. Ahnen, Stanley R. Hamilton, and David S. Alberts
Cancer Res 1999 59: 5181-5185. [Abstract] [Full Text] [PDF]  

Experimental Therapeutics:

Imaging Adenoviral-mediated Herpes Virus Thymidine Kinase Gene Transfer and Expression In Vivo

Juri G. Tjuvajev, Shu Hsia Chen, Arjun Joshi, Revathi Joshi, Zong Sheng Guo, Julius Balatoni, Douglas Ballon, Jason Koutcher, Ronald Finn, Savio L. Woo, and Ronald G. Blasberg
Cancer Res 1999 59: 5186-5193. [Abstract] [Full Text] [PDF]  

Reversal of Radiation Resistance in LNCaP Cells by Targeting Apoptosis through Ceramide Synthase

Mark Garzotto, Adriana Haimovitz-Friedman, Wen-Chieh Liao, Margaret White-Jones, Robert Huryk, Warren D. W. Heston, Carlos Cardon-Cardo, Richard Kolesnick, and Zvi Fuks
Cancer Res 1999 59: 5194-5201. [Abstract] [Full Text] [PDF]  

Eradication of Primary Murine Fibrosarcomas and Induction of Systemic Immunity by Adenovirus-mediated Interferon Gene Therapy

Weixin Lu, Isaiah J. Fidler, and Zhongyun Dong
Cancer Res 1999 59: 5202-5208. [Abstract] [Full Text] [PDF]  

Antivascular Endothelial Growth Factor Receptor (Fetal Liver Kinase 1) Monoclonal Antibody Inhibits Tumor Angiogenesis and Growth of Several Mouse and Human Tumors

Marie Prewett, James Huber, Yiwen Li, Angel Santiago, William O’Connor, Karen King, Jay Overholser, Andrea Hooper, Bronislaw Pytowski, Larry Witte, Peter Bohlen, and Daniel J. Hicklin
Cancer Res 1999 59: 5209-5218. [Abstract] [Full Text] [PDF]  

The Ribonucleoside Diphosphate Reductase Inhibitor (E)-2'-Deoxy-(fluoromethylene)cytidine as a Cytotoxic Radiosensitizer in Vitro

Philippe A. Coucke, Laurent A. Decosterd, Ye-Xiong Li, Eliane Cottin, Xiaoguang Chen, Lin-Quan Sun, Sabine Stern, Nicolas Paschoud, and Juliana Denekamp
Cancer Res 1999 59: 5219-5226. [Abstract] [Full Text] [PDF]  

Shock Wave Permeabilization with Ribosome Inactivating Proteins: A New Approach to Tumor Therapy

Michael Delius and Gerhard Adams
Cancer Res 1999 59: 5227-5232. [Abstract] [Full Text] [PDF]  

Enzyme Prodrug Gene Therapy: Synergistic Use of the Herpes Simplex Virus-Cellular Thymidine Kinase/Ganciclovir System and Thymidylate Synthase Inhibitors for the Treatment of Colon Cancer

Oliver Wildner, R. Michael Blaese, and Fabio Candotti
Cancer Res 1999 59: 5233-5238. [Abstract] [Full Text] [PDF]  

Radiosensitization of Human Tumor Cell Lines Induced by the Adenovirus-mediated Expression of an Anti-Ras Single-Chain Antibody Fragment

Jeffery S. Russell, Frederick F. Lang, Thierry Huet, Michel Janicot, Sunil Chada, Deborah R. Wilson, and Philip J. Tofilon
Cancer Res 1999 59: 5239-5244. [Abstract] [Full Text] [PDF]  

Immunology:

Infiltration of Tumors by Systemically Transferred Tumor-Reactive T Lymphocytes Is Required for Antitumor Efficacy

Shigehiko Mukai, Jørgen Kjærgaard, Suyu Shu, and Gregory E. Plautz
Cancer Res 1999 59: 5245-5249. [Abstract] [Full Text] [PDF]  

Successful Immunotherapy of an Intraocular Tumor in Mice

Luc R. H. M. Schurmans, Annemieke Th. den Boer, Linda Diehl, Ellen I. H. van der Voort, W. Martin Kast, Cornelis J. M. Melief, René E. M. Toes, and Martine J. Jager
Cancer Res 1999 59: 5250-5254. [Abstract] [Full Text] [PDF]  

A Chimeric Cell Adhesion Molecule Mediates Homing of Lymphocytes to Vascularized Tumors

Guido Wiedle, Caroline Johnson-Léger, and Beat A. Imhof
Cancer Res 1999 59: 5255-5263. [Abstract] [Full Text] [PDF]  

Regression of Established B16F10 Melanoma with a Recombinant Listeria monocytogenes Vaccine

Zhen-Kun Pan, Larry M. Weiskirch, and Yvonne Paterson
Cancer Res 1999 59: 5264-5269. [Abstract] [Full Text] [PDF]  

Molecular Biology and Genetics:

Abnormal Fhit Expression in Malignant and Premalignant Lesions of the Cervix

Michael J. Birrer, Denver Hendricks, John Farley, Michael J. Sundborg, Tomas Bonome, Michael J. Walts, and Joseph Geradts
Cancer Res 1999 59: 5270-5274. [Abstract] [Full Text] [PDF]  

Structure-Function Studies of the BTB/POZ Transcriptional Repression Domain from the Promyelocytic Leukemia Zinc Finger Oncoprotein

Xinmin Li, Hongzhuang Peng, David C. Schultz, Jesus M. Lopez-Guisa, Frank J. Rauscher, III, and Ronen Marmorstein
Cancer Res 1999 59: 5275-5282. [Abstract] [Full Text] [PDF]  

The Relationship of DNA Ploidy to Chromosomal Instability in Primary Human Colorectal Cancers

Mutsuko Miyazaki, Tomoko Furuya, Akiko Shiraki, Toshihiko Sato, Atsunori Oga, and Kohsuke Sasaki
Cancer Res 1999 59: 5283-5285. [Abstract] [Full Text] [PDF]  

Regulation by p38 Mitogen-activated Protein Kinase of Adenylate- and Uridylate-Rich Element-mediated Urokinase-Type Plasminogen Activator (uPA) Messenger RNA Stability and uPA-dependent in Vitro Cell Invasion

Lilian Montero and Yoshikuni Nagamine
Cancer Res 1999 59: 5286-5293. [Abstract] [Full Text] [PDF]  

Ataxia Telangiectasia Mutated Deficiency Affects Astrocyte Growth but not Radiosensitivity

Eric C. Gosink, Miriam J. Chong, and Peter J. McKinnon
Cancer Res 1999 59: 5294-5298. [Abstract] [Full Text] [PDF]  

Tumor Biology:

Characterization of Glycosylphosphatidylinositol-linked Molecule CD55/Decay-accelerating Factor as the Receptor for Antibody SC-1-induced Apoptosis

Frank Hensel, Ralph Hermann, Christian Schubert, Nico Abé, Karsten Schmidt, Axel Franke, Andrej Shevchenko, Matthias Mann, Hans Konrad Müller-Hermelink, and H. Peter Vollmers
Cancer Res 1999 59: 5299-5306. [Abstract] [Full Text] [PDF]  

Urokinase Receptor Interacts with _v5 Vitronectin Receptor, Promoting Urokinase-dependent Cell Migration in Breast Cancer

Maria V. Carriero, Silvana Del Vecchio, Monica Capozzoli, Paola Franco, Laura Fontana, Antonella Zannetti, Gerardo Botti, Giuseppe D’Aiuto, Marco Salvatore, and M. Patrizia Stoppelli
Cancer Res 1999 59: 5307-5314. [Abstract] [Full Text] [PDF]  

Ribozyme-mediated Down-Regulation of ErbB-4 in Estrogen Receptor-positive Breast Cancer Cells Inhibits Proliferation Both in Vitro and in Vivo

Careen K. Tang, Xiao-Zheng Wu Concepcion, Melissa Milan, Xiaoqi Gong, Elizabeth Montgomery, and Marc E. Lippman
Cancer Res 1999 59: 5315-5322. [Abstract] [Full Text] [PDF]  

Apoptosis Induction of Human Lung Cancer Cell Line in Multicellular Heterospheroids with Humanized Antiganglioside GM2 Monoclonal Antibody

Kazuyasu Nakamura, Masaki Hanibuchi, Seiji Yano, Yuko Tanaka, Ikuko Fujino, Miho Inoue, Toshiaki Takezawa, Kenya Shitara, Saburo Sone, and Nobuo Hanai
Cancer Res 1999 59: 5323-5330. [Abstract] [Full Text] [PDF]  

Biological Activities and Signaling Pathways of the Granulin/Epithelin Precursor

Tommaso Zanocco-Marani, Andrew Bateman, Gaetano Romano, Barbara Valentinis, Zhi-Heng He, and Renato Baserga
Cancer Res 1999 59: 5331-5340. [Abstract] [Full Text] [PDF]  

Microinjection of Anti-p21 Antibodies Induces Senescent Hs68 Human Fibroblasts to Synthesize DNA but not To Divide

Yuliang Ma, Sally A. Prigent, Teresa L. Born, Craig R. Monell, James R. Feramisco, and Bonnie L. Bertolaet
Cancer Res 1999 59: 5341-5348. [Abstract] [Full Text] [PDF]  

A Mammalian Severin Replaces Gelsolin in Transformed Epithelial Cells

Paula A. Folger, William J. Berg, Zoraida DeJesus, Yuman Fong, and Joel D. Pardee
Cancer Res 1999 59: 5349-5355. [Abstract] [Full Text] [PDF]  

Fas Ligand Is Expressed on Human Squamous Cell Carcinomas of the Head and Neck, and It Promotes Apoptosis of T Lymphocytes

Brian R. Gastman, Yoshinari Atarashi, Torsten E. Reichert, Takao Saito, Levent Balkir, Hannah Rabinowich, and Theresa L. Whiteside
Cancer Res 1999 59: 5356-5364. [Abstract] [Full Text] [PDF]  

Response of Human Tumor Cells of Varying Radiosensitivity and Radiocurability to Fractionated Irradiation

William K. Dahlberg, Edouard I. Azzam, Yongjia Yu, and John B. Little
Cancer Res 1999 59: 5365-5369. [Abstract] [Full Text] [PDF]  

Distinctive Expression and Functions of the Type 4 Endothelial Differentiation Gene-encoded G Protein-coupled Receptor for Lysophosphatidic Acid in Ovarian Cancer

Edward J. Goetzl, Hana Dolezalova, Yvonne Kong, Yu-Long Hu, Robert B. Jaffe, Kimberly R. Kalli, and Cheryl A. Conover
Cancer Res 1999 59: 5370-5375. [Abstract] [Full Text] [PDF]  

Signaling Pathways and Structural Domains Required for Phosphorylation of EMS1/Cortactin

Douglas H. Campbell, Robert L. Sutherland, and Roger J. Daly
Cancer Res 1999 59: 5376-5385. [Abstract] [Full Text] [PDF]  

Immunohistochemical Localization of Caspase-3 Correlates with Clinical Outcome in B-Cell Diffuse Large-Cell Lymphoma

Stephen Donoghue, Hussein S. Baden, Ian Lauder, Stanislaw Sobolewski, and James Howard Pringle
Cancer Res 1999 59: 5386-5391. [Abstract] [Full Text] [PDF]  

Gangliosides Influence Angiogenesis in an Experimental Mouse Brain Tumor

Mark G. Manfredi, Sangmook Lim, Kevin P. Claffey, and Thomas N. Seyfried
Cancer Res 1999 59: 5392-5397. [Abstract] [Full Text] [PDF]  

Correction:

Y-Y. E. Chuang et al., 59: 3073–3076, 1999

Cancer Res 1999 59: 5400 [Full Text]  

Errata:

R. W. Kozak et. al., 49: 2639–2644, 1999

Cancer Res 1999 59: 5400 [Full Text]  

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