Special Lecture:

The Hypoxic Cell: A Target for Selective Cancer Therapy—Eighteenth Bruce F. Cain Memorial Award Lecture

J. Martin Brown
Cancer Res 1999 59: 5863-5870. [Abstract] [Full Text] [PDF]  

Advances in Brief:

Amelioration of Radiation-induced Liver Damage in Partially Hepatectomized Rats by Hepatocyte Transplantation

Chandan Guha, Anand Sharma, Sanjeev Gupta, Alan Alfieri, Giridhar R. Gorla, Singh Gagandeep, Rana Sokhi, Namita Roy-Chowdhury, Kathryn E. Tanaka, Bhadrasain Vikram, and Jayanta Roy-Chowdhury
Cancer Res 1999 59: 5871-5874. [Abstract] [Full Text] [PDF]  

Endothelial Progenitor Cells as Putative Targets for Angiostatin

Hideaki Ito, Ilsa I. Rovira, Michael L. Bloom, Kazuyo Takeda, Victor J. Ferrans, Arshed A. Quyyumi, and Toren Finkel
Cancer Res 1999 59: 5875-5877. [Abstract] [Full Text] [PDF]  

The V89L Polymorphism in the 5-Reductase Type 2 Gene and Risk of Prostate Cancer

Phillip G. Febbo, Philip W. Kantoff, Elizabeth A. Platz, Daniel Casey, Steve Batter, Edward Giovannucci, Charles H. Hennekens, and Meir J. Stampfer
Cancer Res 1999 59: 5878-581. [Abstract] [Full Text] [PDF]  

Spontaneous and Mutagen-induced Transformation of Primary Cultures of Msh2-/- p53-/- Colonocytes

Cinzia Sevignani, Aaron Cranston, Renato V. Iozzo, Richard Fishel, and Bruno Calabretta
Cancer Res 1999 59: 5882-5886. [Abstract] [Full Text] [PDF]  

Sensitization of Cancer Cells to DNA Damage-induced Cell Death by Specific Cell Cycle G₂ Checkpoint Abrogation

Masashi Suganuma, Takumi Kawabe, Haruna Hori, Takahiko Funabiki, and Takashi Okamoto
Cancer Res 1999 59: 5887-5891. [Abstract] [Full Text] [PDF]  

Resveratrol Inhibits the Expression and Function of the Androgen Receptor in LNCaP Prostate Cancer Cells

Susan H. Mitchell, Wen Zhu, and Charles Y. F. Young
Cancer Res 1999 59: 5892-5895. [Abstract] [Full Text] [PDF]  

Combination Therapy with the Farnesyl Protein Transferase Inhibitor SCH66336 and SCH58500 (p53 Adenovirus) in Preclinical Cancer Models

Loretta L. Nielsen, Bin Shi, Gerald Hajian, Bohden Yaremko, Philip Lipari, Eric Ferrari, Maya Gurnani, Michael Malkowski, Jiaping Chen, W. Robert Bishop, and Ming Liu
Cancer Res 1999 59: 5896-5901. [Abstract] [Full Text] [PDF]  

Deletion of the COOH-Terminal Region of p73 Enhances Both Its Transactivation Function and DNA-binding Activity but Inhibits Induction of Apoptosis in Mammalian Cells

Toshinori Ozaki, Masahiko Naka, Naoyuki Takada, Mitsuhiro Tada, Shigeru Sakiyama, and Akira Nakagawara
Cancer Res 1999 59: 5902-5907. [Abstract] [Full Text] [PDF]  

Effects of p51/p63 Missense Mutations on Transcriptional Activities of p53 Downstream Gene Promoters

Shunsuke Kato, Akira Shimada, Motonobu Osada, Shuntaro Ikawa, Masuo Obinata, Akira Nakagawara, Ryunosuke Kanamaru, and Chikashi Ishioka
Cancer Res 1999 59: 5908-5911. [Abstract] [Full Text] [PDF]  

The Bromodeoxyuridine Comet Assay: Detection of Maturation of Recently Replicated DNA in Individual Cells

Angela P. McGlynn, Gillian Wasson, Jacqueline O’Connor, Valerie J. McKelvey-Martin, and C. Stephen Downes
Cancer Res 1999 59: 5912-5916. [Abstract] [Full Text] [PDF]  

Estrogen Activates Telomerase

Satoru Kyo, Masahiro Takakura, Taro Kanaya, Wang Zhuo, Kohtaro Fujimoto, Yukihito Nishio, Akira Orimo, and Masaki Inoue
Cancer Res 1999 59: 5917-5921. [Abstract] [Full Text] [PDF]  

Carcinogenesis:

Role of Oxyradicals in Mutagenicity and DNA Damage Induced by Crocidolite Asbestos in Mammalian Cells

An Xu, Li-Jun Wu, Regina M. Santella, and Tom K. Hei
Cancer Res 1999 59: 5922-5926. [Abstract] [Full Text] [PDF]  

Interferon-inducible Gene Family 1-8U Expression in Colitis-associated Colon Cancer and Severely Inflamed Mucosa in Ulcerative Colitis

Tadakazu Hisamatsu, Mamoru Watanabe, Haruhiko Ogata, Toshihiko Ezaki, Shigenari Hozawa, Hiromasa Ishii, Takanori Kanai, and Toshifumi Hibi
Cancer Res 1999 59: 5927-5931. [Abstract] [Full Text] [PDF]  

Epidemiology and Prevention:

Occupational Exposures and Risk of Gastric Cancer in a Population-basedCase-Control Study

Anna Mia Ekström, Mikael Eriksson, Lars-Erik Hansson, Anders Lindgren, Lisa Beth Signorello, Olof Nyrén, and Lennart Hardell
Cancer Res 1999 59: 5932-5937. [Abstract] [Full Text] [PDF]  

Experimental Therapeutics:

Camptothecin Resistance: Role of the ATP-binding Cassette (ABC), Mitoxantrone-resistance Half-Transporter (MXR), and Potential for Glucuronidation in MXR-expressing Cells

Mariafiorella Brangi, Thomas Litman, Marco Ciotti, Kenryu Nishiyama, Glenda Kohlhagen, Chris Takimoto, Robert Robey, Yves Pommier, Tito Fojo, and Susan E. Bates
Cancer Res 1999 59: 5938-5946. [Abstract] [Full Text] [PDF]  

Retinoid Metabolism in the Prostate: Effects of Administration of the Synthetic Retinoid N-(4-Hydroxyphenyl)retinamide

Kevin C. Lewis and James F. Hochadel
Cancer Res 1999 59: 5947-5955. [Abstract] [Full Text] [PDF]  

Molecular and Biochemical Mechanisms of Fludarabine and Cladribine Resistance in a Human Promyelocytic Cell Line

Emma Månsson, Tatiana Spasokoukotskaja, Jan Sällström, Staffan Eriksson, and Freidoun Albertioni
Cancer Res 1999 59: 5956-5963. [Abstract] [Full Text] [PDF]  

Expression of Multidrug Resistance Protein-3 (Multispecific Organic Anion Transporter-D) in Human Embryonic Kidney 293 Cells Confers Resistance to Anticancer Agents

Hao Zeng, Lisa J. Bain, Martin G. Belinsky, and Gary D. Kruh
Cancer Res 1999 59: 5964-5967. [Abstract] [Full Text] [PDF]  

Immunology:

Autologous T Cells Control B-Chronic Lymphocytic Leukemia Tumor Progression in HumanMouse Radiation Chimera

Avichai Shimoni, Hadar Marcus, Benjamin Dekel, Rachel Shkarchi, Fabian Arditti, Lev Shvidel, Mordechai Shtalrid, Wulf Bucher, Allon Canaan, David Ergas, Alain Berrebi, and Yair Reisner
Cancer Res 1999 59: 5968-5974. [Abstract] [Full Text] [PDF]  

Molecular Biology and Genetics:

DD3::A New Prostate-specific Gene, Highly Overexpressed in Prostate Cancer

Marion J. G. Bussemakers, Adrie van Bokhoven, Gerald W. Verhaegh, Frank P. Smit, Herbert F. M. Karthaus, Jack A. Schalken, Frans M. J. Debruyne, Ning Ru, and William B. Isaacs
Cancer Res 1999 59: 5975-5979. [Abstract] [Full Text] [PDF]  

The CCAAT Displacement Protein/cut Homeodomain Protein Represses Osteocalcin Gene Transcription and Forms Complexes with the Retinoblastoma Protein-related Protein p107 and Cyclin A

Maria F. van Gurp, Jitesh Pratap, Mai Luong, Amjad Javed, Heidi Hoffmann, Antonio Giordano, Janet L. Stein, Ellis J. Neufeld, Jane B. Lian, Gary S. Stein, and André J. van Wijnen
Cancer Res 1999 59: 5980-5988. [Abstract] [Full Text] [PDF]  

Egr-1 Mediates Transcriptional Activation of IGF-II Gene in Response to Hypoxia

Soo-Kyung Bae, Myung-Ho Bae, Mee-Young Ahn, Myung Jin Son, You Mie Lee, Moon-Kyoung Bae, Ok-Hee Lee, Byung Chae Park, and Kyu-Won Kim
Cancer Res 1999 59: 5989-5994. [Abstract] [Full Text] [PDF]  

Tight Association of Loss of Merlin Expression with Loss of Heterozygosity at Chromosome 22q in Sporadic Meningiomas

Keisuke Ueki, Chen Wen-Bin, Yoshitaka Narita, Akio Asai, and Takaaki Kirino
Cancer Res 1999 59: 5995-5998. [Abstract] [Full Text] [PDF]  

Tumor Biology:

bcl-X_s-induced Cell Death in 3T3 Cells Does Not Require or Induce Caspase Activation

Jordan S. Fridman, Mary A. Benedict, and Jonathan Maybaum
Cancer Res 1999 59: 5999-6004. [Abstract] [Full Text] [PDF]  

Short-Chain Fatty Acid Metabolism, Apoptosis, and Apc-initiated Tumorigenesis in the Mouse Gastrointestinal Mucosa

Leonard H. Augenlicht, Gillian M. Anthony, Trudi L. Church, Winfried Edelmann, Raju Kucherlapati, Kan Yang, Martin Lipkin, and Barbara G. Heerdt
Cancer Res 1999 59: 6005-6009. [Abstract] [Full Text] [PDF]  

Inhibitory Effects of Antisense Cathepsin B cDNA Transfection on Invasion and Motility in a Human Osteosarcoma Cell Line

Sabine Krueger, Carsten Haeckel, Frank Buehling, and Albert Roessner
Cancer Res 1999 59: 6010-6014. [Abstract] [Full Text] [PDF]  

Parathyroid Hormone-related Protein as a Growth Regulator of Prostate Carcinoma

Kristiann M. Dougherty, Eric A. G. Blomme, Amy J. Koh, Janet E. Henderson, Kenneth J. Pienta, Thomas J. Rosol, and Laurie K. McCauley
Cancer Res 1999 59: 6015-6022. [Abstract] [Full Text] [PDF]  

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