Advances in Brief:

Cyclooxygenase-2 Expression Is Up-Regulated in Human Pancreatic Cancer

Olga N. Tucker, Andrew J. Dannenberg, Eun K. Yang, Fan Zhang, Lisong Teng, John M. Daly, Robert A. Soslow, Jaime L. Masferrer, Bryan M. Woerner, Alane T. Koki, and Thomas J. Fahey, III
Cancer Res 1999 59: 987-990. [Abstract] [Full Text] [PDF]  

Cyclooxygenase-2 Expression Is Up-Regulated in Squamous Cell Carcinoma of the Head and Neck

Georgette Chan, Jay O. Boyle, Eun K. Yang, Fan Zhang, Peter G. Sacks, Jatin P. Shah, David Edelstein, Robert A. Soslow, Alane T. Koki, Bryan M. Woerner, Jaime L. Masferrer, and Andrew J. Dannenberg
Cancer Res 1999 59: 991-994. [Abstract] [Full Text] [PDF]  

High Frequency of Germ-Line BRCA2 Mutations among Hungarian Male Breast Cancer Patients without Family History

Bela Csokay, Nora Udvarhelyi, Zoltan Sulyok, Istvan Besznyak, Susan Ramus, Bruce Ponder, and Edith Olah
Cancer Res 1999 59: 995-998. [Abstract] [Full Text] [PDF]  

Identification of an Endogenous Dominant-Negative Short Isoform of Caspase-9 That Can Regulate Apoptosis

Srinivasa M. Srinivasula, Manzoor Ahmad, Yin Guo, Yi Zhan, Yuri Lazebnik, Teresa Fernandes-Alnemri, and Emad S. Alnemri
Cancer Res 1999 59: 999-1002. [Abstract] [Full Text] [PDF]  

Carcinogenesis:

Intestinal Metaplasia of Human Stomach Displays Distinct Patterns of Mucin (MUC1, MUC2, MUC5AC, and MUC6) Expression

Celso A. Reis, Leonor David, Pelayo Correa, Fatima Carneiro, Carme de Bolós, Elsa Garcia, Ulla Mandel, Henrik Clausen, and Manuel Sobrinho-Simões
Cancer Res 1999 59: 1003-1007. [Abstract] [Full Text] [PDF]  

Loss of Normal G₁ Checkpoint Control Is an Early Step in Carcinogenesis, Independent of p53 Status

Randi G. Syljuåsen, Bozena Krolewski, and John B. Little
Cancer Res 1999 59: 1008-1014. [Abstract] [Full Text] [PDF]  

Epidemiology and Prevention:

The Relationship between a Polymorphism in CYP17 with Plasma Hormone Levels and Breast Cancer

Christopher A. Haiman, Susan E. Hankinson, Donna Spiegelman, Graham A. Colditz, Walter C. Willett, Frank E. Speizer, Karl T. Kelsey, and David J. Hunter
Cancer Res 1999 59: 1015-1020. [Abstract] [Full Text] [PDF]  

Experimental Therapeutics:

Multiple Mechanisms Confer Drug Resistance to Mitoxantrone in the Human 8226 Myeloma Cell Line

Lori A. Hazlehurst, Nils E. Foley, Mary C. Gleason-Guzman, Miles P. Hacker, Anne E. Cress, Lee W. Greenberger, Mariska C. De Jong, and William S. Dalton
Cancer Res 1999 59: 1021-1028. [Abstract] [Full Text] [PDF]  

Antitumor and Immunotherapeutic Effects of Activated Invasive T Lymphoma Cells That Display Short-Term Interleukin 1 Expression

Elena Voronov, Yacob Weinstein, Daniel Benharroch, Emanuela Cagnano, Rivka Ofir, Maria Dobkin, Rosalyn M. White, Margot Zoller, Vivian Barak, Shraga Segal, and Ron N. Apte
Cancer Res 1999 59: 1029-1035. [Abstract] [Full Text] [PDF]  

A Novel Taxane with Improved Tolerability and Therapeutic Activity in a Panel of Human Tumor Xenografts

Donatella Polizzi, Graziella Pratesi, Monica Tortoreto, Rosanna Supino, Antonella Riva, Ezio Bombardelli, and Franco Zunino
Cancer Res 1999 59: 1036-1040. [Abstract] [Full Text] [PDF]  

Arsenic Trioxide and Melarsoprol Induce Apoptosis in Plasma Cell Lines and in Plasma Cells from Myeloma Patients

Philippe Rousselot, Sylvaine Labaume, Jean-Pierre Marolleau, Jérôme Larghero, Maria-Héléna Noguera, Jean-Claude Brouet, and Jean-Paul Fermand
Cancer Res 1999 59: 1041-1048. [Abstract] [Full Text] [PDF]  

Enhanced Antitumor Activity of 6-Hydroxymethylacylfulvene in Combination with Irinotecan and 5-Fluorouracil in the HT29 Human Colon Tumor Xenograft Model

Carolyn D. Britten, Susan G. Hilsenbeck, S. Gail Eckhardt, Jennifer Marty, Gina Mangold, John R. MacDonald, Eric K. Rowinsky, Daniel D. Von Hoff, and Steve Weitman
Cancer Res 1999 59: 1049-1053. [Abstract] [Full Text] [PDF]  

Altered Pharmacokinetics of a Novel Anticancer Drug, UCN-01, Caused by Specific High Affinity Binding to ₁-Acid Glycoprotein in Humans

Eiichi Fuse, Hiromi Tanii, Katsumi Takai, Kazuki Asanome, Noriaki Kurata, Hiroyuki Kobayashi, Takashi Kuwabara, Satoshi Kobayashi, and Yuichi Sugiyama
Cancer Res 1999 59: 1054-1060. [Abstract] [Full Text] [PDF]  

Immunology:

Human Colon Adenocarcinomas Express a MUC1-associated Novel Carbohydrate Epitope on Core Mucin Glycans Defined by a Monoclonal Antibody (A10) Raised against Murine Ehrlich Tumor Cells

Maite Medina, Desireé Vélez, José A. Asenjo, Gustavo Egea, Francisco X. Real, Juana Gil, and José L. Subiza
Cancer Res 1999 59: 1061-1070. [Abstract] [Full Text] [PDF]  

T-Cell Receptor Transgenic Analysis of Tumor-specific CD8 and CD4 Responses in the Eradication of Solid Tumors

Amanda L. Marzo, Richard A. Lake, Bruce W. S. Robinson, and Bernadette Scott
Cancer Res 1999 59: 1071-1079. [Abstract] [Full Text] [PDF]  

Evidence for Involvement of B Lymphocytes in the Surveillance of Lung Metastasis in the Rat

Ning Quan, Zhao-bin Zhang, Melissa K. Demetrikopoulos, Richard P. Kitson, William H. Chambers, Ronald H. Goldfarb, and Jay M. Weiss
Cancer Res 1999 59: 1080-1089. [Abstract] [Full Text] [PDF]  

Molecular Biology and Genetics:

Hypermethylation of the hMLH1 Gene Promoter in Human Gastric Cancers with Microsatellite Instability

A. Steven Fleisher, Manel Esteller, Suna Wang, Gen Tamura, Hiroyuki Suzuki, Jing Yin, Tong-Tong Zou, John M. Abraham, Dehe Kong, Kara N. Smolinski, Ying-Qiang Shi, Mun-Gan Rhyu, Steven M. Powell, Stephen P. James, Keith T. Wilson, James G. Herman, and Stephen J. Meltzer
Cancer Res 1999 59: 1090-1095. [Abstract] [Full Text] [PDF]  

G-Protein 7 Is Down-Regulated in Cancers and Associated with P 27^kip1-induced Growth Arrest

Kohei Shibata, Shinji Tanaka, Takeshi Shiraishi, Seigo Kitano, and Masaki Mori
Cancer Res 1999 59: 1096-1101. [Abstract] [Full Text] [PDF]  

Increased Ultraviolet Sensitivity and Chromosomal Instability Related to P53 Function in the Xeroderma Pigmentosum Variant

James E. Cleaver, Veena Afzal, Luzviminda Feeney, Mindy McDowell, Walt Sadinski, John P. G. Volpe, David B. Busch, Donna M. Coleman, Deborah W. Ziffer, Yongjia Yu, Hatsumi Nagasawa, and John B. Little
Cancer Res 1999 59: 1102-1108. [Abstract] [Full Text] [PDF]  

Ethylnitrosourea-induced Development of Malignant Schwannomas in the Rat: Two Distinct Loci on Chromosome 10 Involved in Tumor Susceptibility and Oncogenesis

Andrea Kindler-Röhrborn, Bernd U. Kölsch, Christine Fischer, Sabine Held, and Manfred F. Rajewsky
Cancer Res 1999 59: 1109-1114. [Abstract] [Full Text] [PDF]  

Tumor Biology:

Use of A Novel Fibronectin Receptor for Liver Infiltration by a Mouse Lymphoma Cell Line RL-1

Mozammel Haque Gazi and Masafumi Ito
Cancer Res 1999 59: 1115-1119. [Abstract] [Full Text] [PDF]  

Ret-mediated Mitogenesis Requires Src Kinase Activity

Rosa Marina Melillo, Maria Vittoria Barone, Gelsy Lupoli, Anna Maria Cirafici, Francesca Carlomagno, Roberta Visconti, Brona Matoskova, Pier Paolo Di Fiore, Giancarlo Vecchio, Alfredo Fusco, and Massimo Santoro
Cancer Res 1999 59: 1120-1126. [Abstract] [Full Text] [PDF]  

Nonpolarized Secretion of Human Meprin in Colorectal Cancer Generates an Increased Proteolytic Potential in the Stroma

Daniel Lottaz, Christoph A. Maurer, Dagmar Hahn, Markus W. Büchler, and Erwin E. Sterchi
Cancer Res 1999 59: 1127-1133. [Abstract] [Full Text] [PDF]  

Cyclin D1 Overexpression Enhances Radiation-induced Apoptosis and Radiosensitivity in a Breast Tumor Cell Line

José M. Coco Martin, Astrid Balkenende, Tom Verschoor, Francois Lallemand, and Rob Michalides
Cancer Res 1999 59: 1134-1140. [Abstract] [Full Text] [PDF]  

Overproduction of Hyaluronan by Expression of the Hyaluronan Synthase Has2 Enhances Anchorage-independent Growth and Tumorigenicity

Rika Kosaki, Ken Watanabe, and Yu Yamaguchi
Cancer Res 1999 59: 1141-1145. [Abstract] [Full Text] [PDF]  

Nuclear Matrix Targeting of the Protein Kinase CK2 Signal as a Common Downstream Response to Androgen or Growth Factor Stimulation of Prostate Cancer Cells

Chuanhai Guo, Shihui Yu, Alan T. Davis, and Khalil Ahmed
Cancer Res 1999 59: 1146-1151. [Abstract] [Full Text] [PDF]  

Gastrin-releasing Peptide Receptors in the Human Prostate: Relation to Neoplastic Transformation

Regula Markwalder and Jean Claude Reubi
Cancer Res 1999 59: 1152-1159. [Abstract] [Full Text] [PDF]  

Virology:

A Possible Contributory Role of BK Virus Infection in Neuroblastoma Development

Trond Flægstad, Per Arne Andresen, John Inge Johnsen, Samuel Kofi Asomani, Gunn-Eli Jørgensen, Somasuntharam Vignarajan, Anita Kjuul, Per Kogner, and Terje Traavik
Cancer Res 1999 59: 1160-1163. [Abstract] [Full Text] [PDF]  

Errata:

M.A. Davies et al., Cancer Res., 58: 5285–5290, 1998

Cancer Res 1999 59: 1167 [Full Text] [PDF]  

M. E. Burrow et al., Cancer Res., 58: 4940–4946, 1998

Cancer Res 1999 59: 1167 [Full Text] [PDF]  

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