Perspectives in Cancer Research:

Immunoprevention of Cancer: Is the Time Ripe?

Guido Forni, Pier Luigi Lollini, Piero Musiani, and Mario P. Colombo
Cancer Res 2000 60: 2571-2575. [Abstract] [Full Text] [PDF]  

Advances in Brief:

Effects of the Multidrug Transporter P-Glycoprotein on Cellular Responses to Ionizing Radiation

Adam C. Ruth and Igor B. Roninson
Cancer Res 2000 60: 2576-2578. [Abstract] [Full Text] [PDF]  

Influence of Nitric Oxide Synthase II Gene Disruption on Tumor Growth and Metastasis

Qian Shi, Qinghua Xiong, Bailiang Wang, Xiangdong Le, Nasim A. Khan, and Keping Xie
Cancer Res 2000 60: 2579-2583. [Abstract] [Full Text] [PDF]  

Effects of Thomsen-Friedenreich Antigen-specific Peptide P-30 on ß-Galactoside-mediated Homotypic Aggregation and Adhesion to the Endothelium of MDA-MB-435 Human Breast Carcinoma Cells

Vladislav V. Glinsky, Margaret E. Huflejt, Gennadi V. Glinsky, Susan L. Deutscher, and Thomas P. Quinn
Cancer Res 2000 60: 2584-2588. [Abstract] [Full Text] [PDF]  

Breast Cancer Resistance Protein Is Localized at the Plasma Membrane in Mitoxantrone- and Topotecan-resistant Cell Lines

George L. Scheffer, Marc Maliepaard, Adriana C. L. M. Pijnenborg, Margôt A. van Gastelen, Mariska C. de Jong, Anouk B. Schroeijers, Dorina M. van der Kolk, John D. Allen, Douglas D. Ross, Paul van der Valk, William S. Dalton, Jan H. M. Schellens, and Rik J. Scheper
Cancer Res 2000 60: 2589-2593. [Abstract] [Full Text] [PDF]  

Estradiol Induces Functional Inactivation of p53 by Intracellular Redistribution

Anna Maria Molinari, Paola Bontempo, Ettore M. Schiavone, Vincenzo Tortora, M. Antonietta Verdicchio, Massimo Napolitano, Ernesto Nola, Bruno Moncharmont, Nicola Medici, Vincenzo Nigro, Ignazio Armetta, Ciro Abbondanza, and Giovanni A. Puca
Cancer Res 2000 60: 2594-2597. [Abstract] [Full Text] [PDF]  

Monoallelic Amplification of Estrogen Receptor- Expression in Breast Cancer

Eric R. Schuur and Ronald J. Weigel
Cancer Res 2000 60: 2598-2601. [Abstract] [Full Text] [PDF]  

A Novel Transmembrane Serine Protease (TMPRSS3) Overexpressed in Pancreatic Cancer^1,2

Christine Wallrapp, Susanne Hähnel, Friederike Müller-Pillasch, Beata Burghardt, Takeshi Iwamura, Manuel Ruthenbürger, Markus M. Lerch, Guido Adler, and Thomas M. Gress
Cancer Res 2000 60: 2602-2606. [Abstract] [Full Text] [PDF]  

Excision of Tamoxifen-DNA Adducts by the Human Nucleotide Excision Repair System

Shinya Shibutani, Joyce T. Reardon, Naomi Suzuki, and Aziz Sancar
Cancer Res 2000 60: 2607-2610. [Abstract] [Full Text] [PDF]  

Radiation and the Apo2L/TRAIL Apoptotic Pathway Preferentially Inhibit the Colonization of Premalignant Human Breast Cells Overexpressing Cyclin D1

Qun Zhou, Paula Fukushima, William DeGraff, James B. Mitchell, Maryalice Stetler-Stevenson, Avi Ashkenazi, and Patricia S. Steeg
Cancer Res 2000 60: 2611-2615. [Abstract] [Full Text] [PDF]  

Biochemistry and Biophysics:

p16^INK4A Mediates Cyclin Dependent Kinase 4 and 6 Inhibition in Senescent Prostatic Epithelial Cells

Charanjit Sandhu, Donna M. Peehl, and Joyce Slingerland
Cancer Res 2000 60: 2616-2622. [Abstract] [Full Text] [PDF]  

High and Low Fluences of -Particles Induce a G₁ Checkpoint in Human Diploid Fibroblasts

Edouard I. Azzam, Sonia M. de Toledo, Anthony J. Waker, and John B. Little
Cancer Res 2000 60: 2623-2631. [Abstract] [Full Text] [PDF]  

Clinical Investigations:

Clinical Implications of Expression of Interleukin 8 Related to Angiogenesis in Uterine Cervical Cancers

Jiro Fujimoto, Hideki Sakaguchi, Ikumi Aoki, and Teruhiko Tamaya
Cancer Res 2000 60: 2632-2635. [Abstract] [Full Text] [PDF]  

Experimental Therapeutics:

Depletion of Tumor Oxygenation during Photodynamic Therapy: Detection by the Hypoxia Marker EF3 [2-(2-Nitroimidazol-1[H]-yl)-N-(3,3,3-trifluoropropyl)acetamide]

Theresa M. Busch, Stephen M. Hahn, Sydney M. Evans, and Cameron J. Koch
Cancer Res 2000 60: 2636-2642. [Abstract] [Full Text] [PDF]  

Fas-dependent and -independent Mechanisms of Cell Death following DNA Damage in Human Colon Carcinoma Cells

Istvan Petak, David M. Tillman, Franklin G. Harwood, Rudolf Mihalik, and Janet A. Houghton
Cancer Res 2000 60: 2643-2650. [Abstract] [Full Text] [PDF]  

Induction of Apoptosis in Leukemic Cells by the Reversible Microtubule-disrupting Agent 2-Methoxy-5-(2',3',4'-trimethoxyphenyl)-2,4,6-cycloheptatrien-1-one: Protection by Bcl-2 and Bcl-X_L and Cell Cycle Arrest

Consuelo Gajate, Isabel Barasoain, José M. Andreu, and Faustino Mollinedo
Cancer Res 2000 60: 2651-2659. [Abstract] [Full Text] [PDF]  

Liposome-delivered Angiostatin Strongly Inhibits Tumor Growth and Metastatization in a Transgenic Model of Spontaneous Breast Cancer

Maria Grazia Sacco, Mario Caniatti, Enrica Mira Catò, Annalisa Frattini, Giulia Chiesa, Roberta Ceruti, Fulvio Adorni, Luigi Zecca, Eugenio Scanziani, and Paolo Vezzoni
Cancer Res 2000 60: 2660-2665. [Abstract] [Full Text] [PDF]  

Efficient Induction of Cell Death by Adenoviruses Requires Binding of E1B55k and p53

Brett R. Dix, Simon J. O’Carroll, Colleen J. Myers, Sara J. Edwards, and Antony W. Braithwaite
Cancer Res 2000 60: 2666-2672. [Abstract] [Full Text] [PDF]  

Two Novel 14-Epi-Analogues of 1,25-Dihydroxyvitamin D₃ Inhibit the Growth of Human Breast Cancer Cells in Vitro and in Vivo

Lieve Verlinden, Annemieke Verstuyf, Mark Van Camp, Suzanne Marcelis, Katrien Sabbe, Xu-Yang Zhao, Pierre De Clercq, Maurits Vandewalle, and Roger Bouillon
Cancer Res 2000 60: 2673-2679. [Abstract] [Full Text] [PDF]  

Mouse Mammary Tumor Virus-Ki-rasB Transgenic Mice Develop Mammary Carcinomas That Can Be Growth-inhibited by a Farnesyl:Protein Transferase Inhibitor

Charles A. Omer, Zunxuan Chen, Ronald E. Diehl, Michael W. Conner, Howard Y. Chen, Myrna E. Trumbauer, Shobhna Gopal-Truter, Gina Seeburger, Hema Bhimnathwala, Marc T. Abrams, Joseph P. Davide, Michelle S. Ellis, Jackson B. Gibbs, Ian Greenberg, Kelly Hamilton, Kenneth S. Koblan, Astrid M. Kral, Dongming Liu, Robert B. Lobell, Patricia J. Miller, Scott D. Mosser, Timothy J. O’Neill, Elaine Rands, Michael D. Schaber, Edith T. Senderak, Allen Oliff, and Nancy E. Kohl
Cancer Res 2000 60: 2680-2688. [Abstract] [Full Text] [PDF]  

Recombinant Adenovirus Vaccine Encoding a Chimeric T-Cell Antigen Receptor Induces Protective Immunity against a T-Cell Lymphoma

Carmen P. Wong and Ronald Levy
Cancer Res 2000 60: 2689-2695. [Abstract] [Full Text] [PDF]  

Methioninase Gene Therapy of Human Cancer Cells Is Synergistic with Recombinant Methioninase Treatment

Kenji Miki, Waddah Al-Refaie, Mingxu Xu, Ping Jiang, Yuying Tan, Michael Bouvet, Ming Zhao, Anshu Gupta, Takashi Chishima, Hiroshi Shimada, Masatoshi Makuuchi, A. R. Moossa, and Robert M. Hoffman
Cancer Res 2000 60: 2696-2702. [Abstract] [Full Text] [PDF]  

Immunology:

Endogenous Interleukin-18 Modulates Immune Escape of Murine Melanoma Cells by Regulating the Expression of Fas Ligand and Reactive Oxygen Intermediates

Daeho Cho, Hyunkeun Song, Yong Man Kim, Dong Houh, Dae Young Hur, Hyunjeong Park, Doyoung Yoon, Kwang Ho Pyun, Wang Jae Lee, Masashi Kurimoto, Yoon Berm Kim, Young Sang Kim, and Inpyo Choi
Cancer Res 2000 60: 2703-2709. [Abstract] [Full Text] [PDF]  

Cooperativity of Staphylococcal aureus Enterotoxin B Superantigen, Major Histocompatibility Complex Class II, and CD80 for Immunotherapy of Advanced Spontaneous Metastases in a Clinically Relevant Postoperative Mouse Breast Cancer Model

Beth A. Pulaski, David S. Terman, Saleem Khan, Eric Muller, and Suzanne Ostrand-Rosenberg
Cancer Res 2000 60: 2710-2715. [Abstract] [Full Text] [PDF]  

Molecular Biology and Genetics:

Comparison of TP53 Mutations Identified by Oligonucleotide Microarray and Conventional DNA Sequence Analysis

Wen-Hsiang Wen, Leslie Bernstein, Jennifer Lescallett, Yasmin Beazer-Barclay, Jane Sullivan-Halley, Marga White, and Michael F. Press
Cancer Res 2000 60: 2716-2722. [Abstract] [Full Text] [PDF]  

Cytoplasmic Sequestration and Functional Repression of p53 in the Mammary Epithelium Is Reversed by Hormonal Treatment

Charlotte Kuperwasser, Jan Pinkas, Gregory D. Hurlbut, Stephen P. Naber, and D. Joseph Jerry
Cancer Res 2000 60: 2723-2729. [Abstract] [Full Text] [PDF]  

Tumor Biology:

Small Cell Lung Carcinoma Exhibits Greater Phospholipase C-ß1 Expression and Edelfosine Resistance Compared with Non-Small Cell Lung Carcinoma

Derek Strassheim, Shulamith H. Shafer, Scott H. Phelps, and Carol L. Williams
Cancer Res 2000 60: 2730-2736. [Abstract] [Full Text] [PDF]  

Inducible pRb2/p130 Expression and Growth-suppressive Mechanisms: Evidence of a pRb2/p130, p27^Kip1, and Cyclin E Negative Feedback Regulatory Loop

Candace M. Howard, Pier Paolo Claudio, Antonio De Luca, Peter Stiegler, Francesco Paolo Jori, Nabile M. Safdar, Mario Caputi, Kamel Khalili, and Antonio Giordano
Cancer Res 2000 60: 2737-2744. [Abstract] [Full Text] [PDF]  

Virology:

Unique Transcription Pattern of Epstein-Barr Virus (EBV) in EBV-carrying Gastric Adenocarcinomas: Expression of the Transforming BARF1 Gene

Axel zur Hausen, Antoinette A. T. P. Brink, Mikael E. Craanen, Jaap M. Middeldorp, Chris J. L. M. Meijer, and Adriaan J. C. van den Brule
Cancer Res 2000 60: 2745-2748. [Abstract] [Full Text] [PDF]  

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