Review:

Regulation of Angiogenesis via Vascular Endothelial Growth Factor Receptors

Tanja Veikkola, Marika Karkkainen, Lena Claesson-Welsh, and Kari Alitalo
Cancer Res 2000 60: 203-212. [Full Text] [PDF]  

Advances in Brief:

Malonyl-Coenzyme-A Is a Potential Mediator of Cytotoxicity Induced by Fatty-Acid Synthase Inhibition in Human Breast Cancer Cells and Xenografts

Ellen S. Pizer, Jagan Thupari, Wan Fang Han, Michael L. Pinn, Francis J. Chrest, Gojeb L. Frehywot, Craig A. Townsend, and Francis P. Kuhajda
Cancer Res 2000 60: 213-218. [Abstract] [Full Text] [PDF]  

Redox Regulation of Glutathione S-Transferase Induction by Benzyl Isothiocyanate: Correlation of Enzyme Induction with the Formation of Reactive Oxygen Intermediates

Yoshimasa Nakamura, Hajime Ohigashi, Seiji Masuda, Akira Murakami, Yasujiro Morimitsu, Yoshiyuki Kawamoto, Toshihiko Osawa, Masayoshi Imagawa, and Koji Uchida
Cancer Res 2000 60: 219-225. [Abstract] [Full Text] [PDF]  

Evidence That the Epidermal Targets of Carcinogen Action Are Found in the Interfollicular Epidermis or Infundibulum as well as in the Hair Follicles

Rebecca J. Morris, Kimberly A. Tryson, and Kai Q. Wu
Cancer Res 2000 60: 226-229. [Abstract] [Full Text] [PDF]  

Vascular Protection by Chloroquine during Brain Tumor Therapy with Tf-CRM107

Naoshi Hagihara, Stuart Walbridge, Alan W. Olson, Edward H. Oldfield, and Richard J. Youle
Cancer Res 2000 60: 230-234. [Abstract] [Full Text] [PDF]  

Induction of Uterine Adenocarcinoma in CD-1 Mice by Catechol Estrogens

Retha R. Newbold and Joachim G. Liehr
Cancer Res 2000 60: 235-237. [Abstract] [Full Text] [PDF]  

Nickel Compounds Are Novel Inhibitors of Histone H4 Acetylation

Limor Broday, Wu Peng, Min-Hao Kuo, Konstantin Salnikow, Maria Zoroddu, and Max Costa
Cancer Res 2000 60: 238-241. [Abstract] [Full Text] [PDF]  

Prognostic Significance of Cyclin E Overexpression in Resected Non-Small Cell Lung Cancer

Tatsuo Fukuse, Toshiki Hirata, Hironobu Naiki, Shigeki Hitomi, and Hiromi Wada
Cancer Res 2000 60: 242-244. [Abstract] [Full Text] [PDF]  

Selective Loss of Estrogen Receptor ß in Malignant Human Colon

Eugene F. Foley, Amir A. Jazaeri, Margaret A. Shupnik, Omid Jazaeri, and Laurel W. Rice
Cancer Res 2000 60: 245-248. [Abstract] [Full Text] [PDF]  

Effects of Cyclin D1 Polymorphism on Age of Onset of Hereditary Nonpolyposis Colorectal Cancer

Shouming Kong, Christopher I. Amos, Rajyalakshmi Luthra, Patrick M. Lynch, Bernard Levin, and Marsha L. Frazier
Cancer Res 2000 60: 249-252. [Abstract] [Full Text] [PDF]  

Genetic Vaccination with "Self" Tyrosinase-related Protein 2 Causes Melanoma Eradication but not Vitiligo

Vincenzo Bronte, Elisa Apolloni, Roberto Ronca, Paola Zamboni, Willem W. Overwijk, Deborah R. Surman, Nicholas P. Restifo, and Paola Zanovello
Cancer Res 2000 60: 253-258. [Abstract] [Full Text] [PDF]  

The HRAS1 Minisatellite Locus and Risk of Ovarian Cancer

Jeffrey N. Weitzel, Shaofeng Ding, Garry P. Larson, Rebecca A. Nelson, Annekathryn Goodman, Edward C. Grendys, Harrison G. Ball, and Theodore G. Krontiris
Cancer Res 2000 60: 259-261. [Abstract] [Full Text] [PDF]  

Mechanism for Inactivation of the KIP Family Cyclin-dependent Kinase Inhibitor Genes in Gastric Cancer Cells

Jong-Yeon Shin, Hyun-Seok Kim, Jinseu Park, Jae-Bong Park, and Jae-Yong Lee
Cancer Res 2000 60: 262-265. [Abstract] [Full Text] [PDF]  

Prostate Mutations in Rats Induced by the Suspected Human Carcinogen 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

Gregory R. Stuart, James Holcroft, Johan G. de Boer, and Barry W. Glickman
Cancer Res 2000 60: 266-268. [Abstract] [Full Text] [PDF]  

The Angiogenic Factor Interleukin 8 Is Induced in Non-Small Cell Lung Cancer/Pulmonary Fibroblast Cocultures

Ian C. Anderson, Silvie E. Mari, Ryan J. Broderick, Bernard P. Mari, and Margaret A. Shipp
Cancer Res 2000 60: 269-272. [Abstract] [Full Text] [PDF]  

Tamoxifen Chemoprevention of a Hormone-independent Tumor in the Proto-neu Transgenic Mice Model

Sylvie Ménard, Piera Aiello, Elda Tagliabue, Cristiano Rumio, Pier Luigi Lollini, Maria I. Colnaghi, and Andrea Balsari
Cancer Res 2000 60: 273-275. [Abstract] [Full Text] [PDF]  

Heregulin Induces Expression, DNA Binding Activity, and Transactivating Functions of Basic Leucine Zipper Activating Transcription Factor 4

Amjad H. Talukder, Ratna Vadlamudi, Mahitosh Mandal, and Rakesh Kumar
Cancer Res 2000 60: 276-281. [Abstract] [Full Text] [PDF]  

Protein Phosphorylation Is a Regulatory Mechanism for O⁶-Alkylguanine-DNA Alkyltransferase in Human Brain Tumor Cells

Kalkunte S. Srivenugopal, Srinivas R. S. Mullapudi, Jiang Shou, Tapas K. Hazra, and Francis Ali-Osman
Cancer Res 2000 60: 282-287. [Abstract] [Full Text] [PDF]  

Biochemistry:

Nuclear Matrix Proteins Associated with DNA in Situ in Hormone-dependent and Hormone-independent Human Breast Cancer Cell Lines

Virginia A. Spencer, Shanti K. Samuel, and James R. Davie
Cancer Res 2000 60: 288-292. [Abstract] [Full Text] [PDF]  

Carcinogenesis:

Chemoprevention of Colon Cancer by Specific Cyclooxygenase-2 Inhibitor, Celecoxib, Administered during Different Stages of Carcinogenesis

Bandaru S. Reddy, Yoshinobu Hirose, Ronald Lubet, Vernon Steele, Gary Kelloff, Susan Paulson, Karen Seibert, and Chinthalapally V. Rao
Cancer Res 2000 60: 293-297. [Abstract] [Full Text] [PDF]  

Clinical Investigations:

Separating Favorable from Unfavorable Prognostic Markers in Breast Cancer: The Role of E-Cadherin

Ruth Heimann, Fusheng Lan, Russell McBride, and Samuel Hellman
Cancer Res 2000 60: 298-304. [Abstract] [Full Text] [PDF]  

Epidemiology and Prevention:

Association of Vitamin D Receptor Gene Polymorphism with Prostate Cancer and Benign Prostatic Hyperplasia in a Japanese Population

Tomonori Habuchi, Takehiro Suzuki, Ryusei Sasaki, Lizhong Wang, Kazunari Sato, Shigeru Satoh, Toshiya Akao, Norihiko Tsuchiya, Naotake Shimoda, Yasuhiko Wada, Akio Koizumi, Junichi Chihara, Osamu Ogawa, and Tetsuro Kato
Cancer Res 2000 60: 305-308. [Abstract] [Full Text] [PDF]  

Experimental Therapeutics:

Anti-invasive, Antitumorigenic, and Antimetastatic Activities of the PHSCN Sequence in Prostate Carcinoma

Donna L. Livant, R. Kaye Brabec, Kenneth J. Pienta, David L. Allen, Kotoku Kurachi, Sonja Markwart, and Ameet Upadhyaya
Cancer Res 2000 60: 309-320. [Abstract] [Full Text] [PDF]  

Radiation-induced Apoptosis of Endothelial Cells in the Murine Central Nervous System: Protection by Fibroblast Growth Factor and Sphingomyelinase Deficiency

Louis A. Peña, Zvi Fuks, and Richard N. Kolesnick
Cancer Res 2000 60: 321-327. [Abstract] [Full Text] [PDF]  

Differential Toxicities of Anticancer Agents among DNA Repair and Checkpoint Mutants of Saccharomyces cerevisiae

Julian A. Simon, Philippe Szankasi, Di K. Nguyen, Catherine Ludlow, Heather M. Dunstan, Christopher J. Roberts, Elizabeth L. Jensen, Leland H. Hartwell, and Stephen H. Friend
Cancer Res 2000 60: 328-333. [Abstract] [Full Text] [PDF]  

Prostate-specific Antigen Promoter/Enhancer Driven Gene Therapy for Prostate Cancer: Construction and Testing of a Tissue-specific Adenovirus Vector

James P. F. Latham, Peter F. Searle, Vivien Mautner, and Nicholas D. James
Cancer Res 2000 60: 334-341. [Abstract] [Full Text] [PDF]  

The Geldanamycins Are Potent Inhibitors of the Hepatocyte Growth Factor/Scatter Factor-Met-Urokinase Plasminogen Activator-Plasmin Proteolytic Network

Craig P. Webb, Curtis D. Hose, Shahriar Koochekpour, Michael Jeffers, Marianne Oskarsson, Edward Sausville, Anne Monks, and George F. Vande Woude
Cancer Res 2000 60: 342-349. [Abstract] [Full Text] [PDF]  

Effective Elimination of Lung Metastases Induced by Tumor Cells Treated with Hydrostatic Pressure and N-Acetyl-L-Cysteine

Yechiel Goldman, Alpha Peled, and Meir Shinitzky
Cancer Res 2000 60: 350-358. [Abstract] [Full Text] [PDF]  

Immunology:

Ability of Systemic Interleukin-12 to Hamper Progressive Stages of Mammary Carcinogenesis in HER2/neu Transgenic Mice

Katia Boggio, Emma Di Carlo, Stefania Rovero, Federica Cavallo, Elena Quaglino, Pier Luigi Lollini, Patrizia Nanni, Giordano Nicoletti, Stanley Wolf, Piero Musiani, and Guido Forni
Cancer Res 2000 60: 359-364. [Abstract] [Full Text] [PDF]  

Use of Fluorogenic Histocompatibility Leukocyte Antigen-A*0201/HPV 16 E7 Peptide Complexes to Isolate Rare Human Cytotoxic T-Lymphocyte- recognizing Endogenous Human Papillomavirus Antigens

Sarah J. Youde, P. R. Rod Dunbar, Eve M. L. Evans, Alison N. Fiander, Leszek K. Borysiewicz, Vincenzo Cerundolo, and Stephen Man
Cancer Res 2000 60: 365-371. [Abstract] [Full Text] [PDF]  

Molecular Biology and Genetics:

Mutations in the Retinoblastoma-related Gene RB2/p130 in Lung Tumors and Suppression of Tumor Growth in Vivo by Retrovirus-mediated Gene Transfer

Pier Paolo Claudio, Candace M. Howard, Carmen Pacilio, Caterina Cinti, Gaetano Romano, Corrado Minimo, Nadir M. Maraldi, John D. Minna, Larry Gelbert, Lorenzo Leoncini, Gian Marco Tosi, Pietro Hicheli, Mario Caputi, Giovan Giacomo Giordano, and Antonio Giordano
Cancer Res 2000 60: 372-382. [Abstract] [Full Text] [PDF]  

Genetic Alterations Disrupting the Nuclear Localization of the Retinoblastoma-related Gene RB2/p130 in Human Tumor Cell Lines and Primary Tumors

Caterina Cinti, Pier Paolo Claudio, Candace M. Howard, Luca Maria Neri, Yan Fu, Lorenzo Leoncini, Gian Marco Tosi, Nadir Mario Maraldi, and Antonio Giordano
Cancer Res 2000 60: 383-389. [Abstract] [Full Text] [PDF]  

Induced Micronucleus Frequencies in Peripheral Lymphocytes as a Screening Test for Carriers of a BRCA1 Mutation in Breast Cancer Families

Andreas Rothfuss, Petra Schütz, Sylvia Bochum, Tanja Volm, Elke Eberhardt, Rolf Kreienberg, Walther Vogel, and Günter Speit
Cancer Res 2000 60: 390-394. [Abstract] [Full Text] [PDF]  

Atm Deficiency Causes an Increased Frequency of Intrachromosomal Homologous Recombination in Mice

Alexander J. R. Bishop, Carrolee Barlow, Anthony J. Wynshaw-Boris, and Robert H. Schiestl
Cancer Res 2000 60: 395-399. [Abstract] [Full Text] [PDF]  

A Dominant Role for the c-Jun NH₂-Terminal Kinase in Oncogenic Ras-induced Morphologic Transformation of Human Lung Carcinoma Cells

Lei Xiao and Wenhua Lang
Cancer Res 2000 60: 400-408. [Abstract] [Full Text] [PDF]  

Inherited Predisposition to Pancreatic Adenocarcinoma: Role of Family History and Germ-Line p16, BRCA1, and BRCA2 Mutations

Geeta Lal, Geoffrey Liu, Beverley Schmocker, Pardeep Kaurah, Hilmi Ozcelik, Steven A. Narod, Mark Redston, and Steven Gallinger
Cancer Res 2000 60: 409-416. [Abstract] [Full Text] [PDF]  

Deregulation of the p14^ARF/MDM2/p53 Pathway Is a Prerequisite for Human Astrocytic Gliomas with G₁-S Transition Control Gene Abnormalities

Koichi Ichimura, Maria Bondesson Bolin, Helena M. Goike, Esther E. Schmidt, Ahmad Moshref, and V. Peter Collins
Cancer Res 2000 60: 417-424. [Abstract] [Full Text] [PDF]  

ZK7, a Novel Zinc Finger Gene, Is Induced by Vascular Endothelial Growth Factor and Inhibits Apoptotic Death in Hematopoietic Cells

Ken Kuramoto, Toshihiro Uesaka, Akiro Kimura, Masao Kobayashi, Hiromitsu Watanabe, and Osamu Katoh
Cancer Res 2000 60: 425-430. [Abstract] [Full Text] [PDF]  

The Cancer-free Phenotype in Trichothiodystrophy Is Unrelated to Its Repair Defect

Mark Berneburg, Peter H. Clingen, Susan A. Harcourt, Jillian E. Lowe, Elaine M. Taylor, Michael H. L. Green, Jean Krutmann, Colin F. Arlett, and Alan R. Lehmann
Cancer Res 2000 60: 431-438. [Abstract] [Full Text] [PDF]  

Tumor Biology:

Interaction with Endothelial Cells Is a Prerequisite for Branching Ductal-Alveolar Morphogenesis and Hyperplasia of Preneoplastic Human Breast Epithelial Cells: Regulation by Estrogen

Malathy P. V. Shekhar, Jill Werdell, and Larry Tait
Cancer Res 2000 60: 439-449. [Abstract] [Full Text] [PDF]  

A Peptide Mimic of E-Selectin Ligand Inhibits Sialyl Lewis X-dependent Lung Colonization of Tumor Cells

Michiko N. Fukuda, Chikara Ohyama, Kevin Lowitz, Osamu Matsuo, Renata Pasqualini, Erkki Ruoslahti, and Minoru Fukuda
Cancer Res 2000 60: 450-456. [Abstract] [Full Text] [PDF]  

Thrombospondin-1 Promotes 3ß1 Integrin-mediated Adhesion and Neurite-like Outgrowth and Inhibits Proliferation of Small Cell Lung Carcinoma Cells

Neng-hua Guo, Nancy Smyth Templeton, Hebah Al-Barazi, JoAnne Cashel, John M. Sipes, Henry C. Krutzsch, and David D. Roberts
Cancer Res 2000 60: 457-466. [Abstract] [Full Text] [PDF]  

A Specific Sequence of the Noncollagenous Domain of the 3(IV) Chain of Type IV Collagen Inhibits Expression and Activation of Matrix Metalloproteinases by Tumor Cells

Sylvie Pasco, Jing Han, Philippe Gillery, Georges Bellon, François-Xavier Maquart, Jacques P. Borel, Nicholas A. Kefalides, and Jean Claude Monboisse
Cancer Res 2000 60: 467-473. [Abstract] [Full Text] [PDF]  

Heregulin Regulation of Autocrine Motility Factor Expression in Human Tumor Cells

Amjad H. Talukder, Liana Adam, Avraham Raz, and Rakesh Kumar
Cancer Res 2000 60: 474-480. [Abstract] [Full Text] [PDF]  

Processing of Cyclin E Differs between Normal and Tumor Breast Cells

Richard M. Harwell, Donald C. Porter, Christopher Danes, and Khandan Keyomarsi
Cancer Res 2000 60: 481-489. [Abstract] [Full Text] [PDF]  

Oncogenes and Tumor Angiogenesis: Differential Modes of Vascular Endothelial Growth Factor Up-Regulation in ras-transformed Epithelial Cells and Fibroblasts

Janusz Rak, Yoshihiro Mitsuhashi, Cap Sheehan, Ami Tamir, Alicia Viloria-Petit, Jorge Filmus, Sam J. Mansour, Natalie G. Ahn, and Robert S. Kerbel
Cancer Res 2000 60: 490-498. [Abstract] [Full Text] [PDF]  

Letter to the Editor:

Correspondence re: J. L. Stanford et al., Polymorphic Receptor in the Androgen Receptor Gene: Molecular Markers of Prostate Cancer Risk. Cancer Res., 57: 1194–1198, 1997.

Takahiro Yasui
Cancer Res 2000 60: 499 [Full Text] [PDF]  

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