Advances in Brief:

Induction of Apoptotic Cell Death and in Vivo Growth Inhibition of Human Cancer Cells by a Saturated Branched-Chain Fatty Acid, 13-Methyltetradecanoic Acid

Zhenhua Yang, Shangpei Liu, Xudong Chen, Hang Chen, Mei Huang, and Jianping Zheng
Cancer Res 2000 60: 505-509. [Abstract] [Full Text] [PDF]  

Expression of a Highly Conserved Protein, p27^BBP, during the Progression of Human Colorectal Cancer

Francesca Sanvito, Federica Vivoli, Stefania Gambini, Graziella Santambrogio, Marco Catena, Edi Viale, Fabrizio Veglia, Alessandra Donadini, Stefano Biffo, and Pier Carlo Marchisio
Cancer Res 2000 60: 510-516. [Abstract] [Full Text] [PDF]  

p53-dependent Global Genomic Repair of Benzo[a]pyrene-7,8-diol-9,10-epoxide Adducts in Human Cells

Daniel R. Lloyd and Philip C. Hanawalt
Cancer Res 2000 60: 517-521. [Abstract] [Full Text] [PDF]  

High Frequency of K-ras Mutations in Biliary Duct Carcinomas of Cases with a Long Common Channel in the Papilla of Vater

Eiji Hidaka, Akio Yanagisawa, Makoto Seki, Kouichi Takano, Toshiaki Setoguchi, and Yo Kato
Cancer Res 2000 60: 522-524. [Abstract] [Full Text] [PDF]  

Photofrin Photodynamic Therapy Can Significantly Deplete or Preserve Oxygenation in Human Basal Cell Carcinomas during Treatment, Depending on Fluence Rate

Barbara W. Henderson, Theresa M. Busch, Lurine A. Vaughan, Noreen P. Frawley, Debra Babich, Tara A. Sosa, Joseph D. Zollo, Anthony S. Dee, Michele T. Cooper, David A. Bellnier, William R. Greco, and Allan R. Oseroff
Cancer Res 2000 60: 525-529. [Abstract] [Full Text] [PDF]  

Differences in Estrogen Receptor Variant Messenger RNAs between Normal Human Breast Tissue and Primary Breast Carcinomas

Mariska A. J. van Dijk, Augustinus A. M. Hart, and Laura J. van’t Veer
Cancer Res 2000 60: 530-533. [Abstract] [Full Text] [PDF]  

High-Activity Microsomal Epoxide Hydrolase Genotypes and the Risk of Oral, Pharynx, and Larynx Cancers

Nadejda Jourenkova-Mironova, Katja Mitrunen, Christine Bouchardy, Pierre Dayer, Simone Benhamou, and Ari Hirvonen
Cancer Res 2000 60: 534-536. [Abstract] [Full Text] [PDF]  

Methylation of the Human Telomerase Gene CpG Island

Scott K. Dessain, Hua-yin Yu, Roger R. Reddel, Roderick L. Beijersbergen, and Robert A. Weinberg
Cancer Res 2000 60: 537-541. [Abstract] [Full Text] [PDF]  

Constitutive Activation of Cyclin B1-associated cdc2 Kinase Overrides p53-mediated G₂-M Arrest

Misoon Park, Hee-Don Chae, Jeanho Yun, Moonsu Jung, Yeon-Soo Kim, Sung-Ho Kim, Moon Hi Han, and Deug Y. Shin
Cancer Res 2000 60: 542-545. [Abstract] [Full Text] [PDF]  

No Evidence of Peutz-Jeghers Syndrome Gene LKB1 Involvement in Left-sided Colorectal Carcinomas

Virpi Launonen, Egle Avizienyte, Anu Loukola, Päivi Laiho, Reijo Salovaara, Heikki Järvinen, Jukka-Pekka Mecklin, Asuka Oku, Miyuki Shimane, Hee C. Kim, Jin C. Kim, Jun-ichi Nezu, and Lauri A. Aaltonen
Cancer Res 2000 60: 546-548. [Abstract] [Full Text] [PDF]  

Genomic Imbalances Including Amplification of the Tyrosine Kinase Gene JAK2 in CD30⁺ Hodgkin Cells

Stefan Joos, Manfred Küpper, Sibylle Ohl, Frederike von Bonin, Gunhild Mechtersheimer, Martin Bentz, Peter Marynen, Peter Möller, Michael Pfreundschuh, Lorenz Trümper, and Peter Lichter
Cancer Res 2000 60: 549-552. [Abstract] [Full Text] [PDF]  

Regulation of Tumor Necrosis Factor-related Apoptosis-inducing Ligand Sensitivity in Primary and Transformed Human Keratinocytes

Martin Leverkus, Manfred Neumann, Thilo Mengling, Charles T. Rauch, Eva-Bettina Bröcker, Peter H. Krammer, and Henning Walczak
Cancer Res 2000 60: 553-559. [Abstract] [Full Text] [PDF]  

Down-Regulation of HER2/neu Expression Induces Apoptosis in Human Cancer Cells That Overexpress HER2/neu

Haeri Roh, James Pippin, and Jeffrey A. Drebin
Cancer Res 2000 60: 560-565. [Abstract] [Full Text] [PDF]  

Biochemistry:

An Indolocarbazole Inhibitor of Human Checkpoint Kinase (Chk1) Abrogates Cell Cycle Arrest Caused by DNA Damage

Jeffrey R. Jackson, Aidan Gilmartin, Christina Imburgia, James D. Winkler, Lisa A. Marshall, and Amy Roshak
Cancer Res 2000 60: 566-572. [Abstract] [Full Text] [PDF]  

Quantitative Analysis of Interindividual Variation of Glutathione S-Transferase Expression in Human Pancreas and the Ambiguity of Correlating Genotype with Phenotype

Brian F. Coles, Kristin E. Anderson, Daniel R. Doerge, Mona I. Churchwell, Nicholas P. Lang, and Fred F. Kadlubar
Cancer Res 2000 60: 573-579. [Abstract] [Full Text] [PDF]  

Carcinogenesis:

Differentiation of Rat Oval Cells after Activation of Peroxisome Proliferator-activated Receptor 43

Catherine Kaplanski, Cindy J. Pauley, Thomas G. Griffiths, Thomas T. Kawabata, and Brian J. Ledwith
Cancer Res 2000 60: 580-587. [Abstract] [Full Text] [PDF]  

Single-Site Methylation within the p53 Promoter Region Reduces Gene Expression in a Reporter Gene Construct: Possible in Vivo Relevance during Tumorigenesis

Igor P. Pogribny, Marta Pogribna, Judith K. Christman, and S. Jill James
Cancer Res 2000 60: 588-594. [Abstract] [Full Text] [PDF]  

Transgenic Mice Overexpressing Protein Kinase C in Their Epidermis Exhibit Reduced Papilloma Burden but Enhanced Carcinoma Formation after Tumor Promotion

Peter J. Reddig, Nancy E. Dreckschmidt, Jun Zou, Sarah E. Bourguignon, Terry D. Oberley, and Ajit K. Verma
Cancer Res 2000 60: 595-602. [Abstract] [Full Text] [PDF]  

Cell Proliferation Induced by Triiodothyronine in Rat Liver Is Associated with Nodule Regression and Reduction of Hepatocellular Carcinomas

Giovanna M. Ledda-Columbano, Andrea Perra, Roberto Loi, Hisashi Shinozuka, and Amedeo Columbano
Cancer Res 2000 60: 603-609. [Abstract] [Full Text] [PDF]  

Clinical Investigations:

Telomerase Activity and Telomere Length in Acute and Chronic Leukemia, Pre- and Post-ex Vivo Culture

Monika Engelhardt, Karen Mackenzie, Pamela Drullinsky, Richard T. Silver, and Malcolm A. S. Moore
Cancer Res 2000 60: 610-617. [Abstract] [Full Text] [PDF]  

Altered Hepatic Gluconeogenesis during L-Alanine Infusion in Weight-losing Lung Cancer Patients as Observed by Phosphorus Magnetic Resonance Spectroscopy and Turnover Measurements

Susanne Leij-Halfwerk, J. Willem O. van den Berg, Paul E. Sijens, J. H. Paul Wilson, Matthijs Oudkerk, and Pieter C. Dagnelie
Cancer Res 2000 60: 618-623. [Abstract] [Full Text] [PDF]  

Imaging Brain Tumor Proliferative Activity with [¹²⁴I]Iododeoxyuridine

Ronald G. Blasberg, Ulrich Roelcke, Regin Weinreich, Bradley Beattie, Klaus von Ammon, Yasuhiro Yonekawa, Hans Landolt, Ilonka Guenther, Nigel E. A. Crompton, Peter Vontobel, John Missimer, Ralph P. Maguire, Jacek Koziorowski, E. Joachim Knust, Ronald D. Finn, and Klaus L. Leenders
Cancer Res 2000 60: 624-635. [Abstract] [Full Text] [PDF]  

The Urokinase System of Plasminogen Activation and Prognosis in 2780 Breast Cancer Patients

John A. Foekens, Harry A. Peters, Maxime P. Look, Henk Portengen, Manfred Schmitt, Michael D. Kramer, Nils Brünner, Fritz Jänicke, Marion E. Meijer-van Gelder, Sonja C. Henzen-Logmans, Wim L. J. van Putten, and Jan G. M. Klijn
Cancer Res 2000 60: 636-643. [Abstract] [Full Text] [PDF]  

Epidemiology and Prevention:

Substantially Reduced Risk of Cancer of the Aerodigestive Tract in Subjects with Variant -463A of the Myeloperoxidase Gene

Ingolf Cascorbi, Stefan Henning, Jürgen Brockmöller, Jürgen Gephart, Christian Meisel, Joachim M. Müller, Robert Loddenkemper, and Ivar Roots
Cancer Res 2000 60: 644-649. [Abstract] [Full Text] [PDF]  

Experimental Therapeutics:

Manumycin Enhances the Cytotoxic Effect of Paclitaxel on Anaplastic Thyroid Carcinoma Cells

Sai-Ching Jim Yeung, Guangpu Xu, Jingxuan Pan, Michelle Christgen, and Alexander Bamiagis
Cancer Res 2000 60: 650-656. [Abstract] [Full Text] [PDF]  

Expression of Endogenously Activated Secreted or Cell Surface Carboxypeptidase A Sensitizes Tumor Cells to Methotrexate--Peptide Prodrugs

Daniel A. Hamstra, Michel Pagé, Jonathan Maybaum, and Alnawaz Rehemtulla
Cancer Res 2000 60: 657-665. [Abstract] [Full Text] [PDF]  

Tumor-targeting Chemotherapy by a Xanthine Oxidase-Polymer Conjugate That Generates Oxygen-free Radicals in Tumor Tissue

Tomohiro Sawa, Jun Wu, Takaaki Akaike, and Hiroshi Maeda
Cancer Res 2000 60: 666-671. [Abstract] [Full Text] [PDF]  

Functional Interactions between Bile Acids, All-Trans Retinoic Acid, and 1,25-Dihydroxy-Vitamin D₃ on Monocytic Differentiation and Myeloblastin Gene Down-Regulation in HL60 and THP-1 Human Leukemia Cells

Amazia Zimber, Annick Chedeville, Jean-Pierre Abita, Veronique Barbu, and Christian Gespach
Cancer Res 2000 60: 672-678. [Abstract] [Full Text] [PDF]  

p21^WAF1/CIP1 Antisense Therapy Radiosensitizes Human Colon Cancer by Converting Growth Arrest to Apoptosis

Hui Tian, Ellen K. Wittmack, and Timothy J. Jorgensen
Cancer Res 2000 60: 679-684. [Abstract] [Full Text] [PDF]  

Immunology:

Interleukin-7/B7.1-encoding Adenoviruses Induce Rejection of Transplanted but not Nontransplanted Tumors

Gerald Willimsky and Thomas Blankenstein
Cancer Res 2000 60: 685-692. [Abstract] [Full Text] [PDF]  

Targeting of Human p53-overexpressing Tumor Cells by an HLA A*0201-restricted Murine T-Cell Receptor Expressed in Jurkat T Cells

Xiping Liu, Elizabeth A. Peralta, Joshua D. I. Ellenhorn, and Don J. Diamond
Cancer Res 2000 60: 693-701. [Abstract] [Full Text] [PDF]  

Molecular Biology & Genetics:

Frequent Methylation of Estrogen Receptor in Prostate Cancer: Correlation with Tumor Progression

Long-Cheng Li, Richard Chui, Koichi Nakajima, Bong Ryoul Oh, Harry C. Au, and Rajvir Dahiya
Cancer Res 2000 60: 702-706. [Abstract] [Full Text] [PDF]  

Detection of Plasma Tumor DNA in Head and Neck Squamous Cell Carcinoma by Microsatellite Typing and p53 Mutation Analysis

Florence Coulet, Helene Blons, Arnauld Cabelguenne, Thierry Lecomte, Olivier Laccourreye, Daniel Brasnu, Philippe Beaune, Jessica Zucman, and Pierre Laurent-Puig
Cancer Res 2000 60: 707-711. [Abstract] [Full Text] [PDF]  

Tumor Biology:

Integrins _vß₃ and _vß₅ Are Expressed by Endothelium of High-Risk Neuroblastoma and Their Inhibition Is Associated with Increased Endogenous Ceramide

Anat Erdreich-Epstein, Hiroyuki Shimada, Susan Groshen, Ming Liu, Leonid S. Metelitsa, Kwang Sik Kim, Monique F. Stins, Robert C. Seeger, and Donald L. Durden
Cancer Res 2000 60: 712-721. [Abstract] [Full Text] [PDF]  

Aminopeptidase N Is a Receptor for Tumor-homing Peptides and a Target for Inhibiting Angiogenesis

Renata Pasqualini, Erkki Koivunen, Renate Kain, Johanna Lahdenranta, Michiie Sakamoto, Anette Stryhn, Richard A. Ashmun, Linda H. Shapiro, Wadih Arap, and Erkki Ruoslahti
Cancer Res 2000 60: 722-727. [Abstract] [Full Text] [PDF]  

Selective Expression and Constitutive Phosphorylation of SHC Proteins in the CD34⁺ Fraction of Chronic Myelogenous Leukemias

Antonio Bonati, Carmelo Carlo-Stella, Paolo Lunghi, Roberto Albertini, Silvana Pinelli, Enrica Migliaccio, Gabriella Sammarelli, Barbara Savoldo, Antonio Tabilio, Pier Paolo Dall’Aglio, and Pier Giuseppe Pelicci
Cancer Res 2000 60: 728-732. [Abstract] [Full Text] [PDF]  

Basic Fibroblast Growth Factor Confers a Less Malignant Phenotype in MDA-MB-231 Human Breast Cancer Cells

Reju M. Korah, Vilayvanh Sysounthone, Yosef Golowa, and Robert Wieder
Cancer Res 2000 60: 733-740. [Abstract] [Full Text] [PDF]  

Androgen Deprivation of the Prohormone Convertase-310 Human Prostate Cancer Model System Induces Neuroendocrine Differentiation

Johan Jongsma, Monique H. Oomen, Marinus A. Noordzij, Wytske M. Van Weerden, Gerard J. M. Martens, Theodorus H. van der Kwast, Fritz H. Schröder, and Gert J. van Steenbrugge
Cancer Res 2000 60: 741-748. [Abstract] [Full Text] [PDF]  

Drg-1 as a Differentiation-related, Putative Metastatic Suppressor Gene in Human Colon Cancer

Rong J. Guan, Heide L. Ford, Yineng Fu, Youzhi Li, Leslie M. Shaw, and Arthur B. Pardee
Cancer Res 2000 60: 749-755. [Abstract] [Full Text] [PDF]  

A Precursor Form of Prostate-specific Antigen Is More Highly Elevated in Prostate Cancer Compared with Benign Transition Zone Prostate Tissue

Stephen D. Mikolajczyk, Lisa S. Millar, Tang J. Wang, Harry G. Rittenhouse, Leonard S. Marks, Weitao Song, Thomas M. Wheeler, and Kevin M. Slawin
Cancer Res 2000 60: 756-759. [Abstract] [Full Text] [PDF]  

Down-Regulation of the Insulin-like Growth Factor I Receptor by Antisense RNA Can Reverse the Transformed Phenotype of Human Cervical Cancer Cell Lines

Keiichiro Nakamura, Atsushi Hongo, Junichi Kodama, Yasunari Miyagi, Mitsuo Yoshinouchi, and Takafumi Kudo
Cancer Res 2000 60: 760-765. [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Correspondence re: S. Shintani et al., Intragenic Mutation Analysis of the Human Epidermal Growth Factor Receptor (EGFR) Gene in Malignant Human Oral Keratinocytes. Cancer Res., 59: 4142–4147, 1999.

Jill L. Reiter, Greg Eley, C. David James, Nita J. Maihle, and David Wong
Cancer Res 2001 60: 766 [Full Text] [PDF]  

Meeting Report:

Eleventh Annual Pezcoller Symposium: Molecular Horizons in Cancer Therapeutics

Enrico Mihich and David Livingston
Cancer Res 2000 60: 768-773. [Full Text] [PDF]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.