Review:

p53 Antibodies in the Sera of Patients with Various Types of Cancer: A Review

Thierry Soussi
Cancer Res 2000 60: 1777-1788. [Abstract] [Full Text] [PDF]  

Advances in Brief:

Acute Doxorubicin Cardiotoxicity Involves Cardiomyocyte Apoptosis

Olli J. Arola, Antti Saraste, Kari Pulkki, Markku Kallajoki, Martti Parvinen, and Liisa-Maria Voipio-Pulkki
Cancer Res 2000 60: 1789-1792. [Abstract] [Full Text] [PDF]  

Antitumor Activity of Endostatin against Carcinogen-induced Rat Primary Mammary Tumors

Gianpaolo Perletti, Paola Concari, Roberto Giardini, Emanuela Marras, Francesco Piccinini, Judah Folkman, and Longchuan Chen
Cancer Res 2000 60: 1793-1796. [Abstract] [Full Text] [PDF]  

Gene Transfer into Brain Parenchyma Elicits Antitumor Effects

Hassan M. Fathallah-Shaykh, Abdallah I. Kafrouni, Li-Juan Zhao, George M. Smith, and James Forman
Cancer Res 2000 60: 1797-1799. [Abstract] [Full Text] [PDF]  

Relative Reciprocity of NRAS and PTEN/MMAC1 Alterations in Cutaneous Melanoma Cell Lines

Hensin Tsao, Xue Zhang, Kianna Fowlkes, and Frank G. Haluska
Cancer Res 2000 60: 1800-1804. [Abstract] [Full Text] [PDF]  

Cyclooxygenase-2, a Colorectal Cancer Nonsteroidal Anti-inflammatory Drug Target, Is Regulated by c-MYB

Robert G. Ramsay, Annabel Friend, Yotta Vizantios, Ruth Freeman, Catherine Sicurella, Fleur Hammett, Jane Armes, and Deon Venter
Cancer Res 2000 60: 1805-1809. [Abstract] [Full Text] [PDF]  

Estrogen Receptor Protects p53 from Deactivation by Human Double Minute-2

Guozhen Liu, Janice A. Schwartz, and Sam C. Brooks
Cancer Res 2000 60: 1810-1814. [Abstract] [Full Text] [PDF]  

Antibody Response to the Tumor-associated Inhibitor of Apoptosis Protein Survivin in Cancer Patients

Jacques Rohayem, Petra Diestelkoetter, Bernd Weigle, Antje Oehmichen, Marc Schmitz, Juergen Mehlhorn, Karsten Conrad, and Ernst Peter Rieber
Cancer Res 2000 60: 1815-1817. [Abstract] [Full Text] [PDF]  

Inhibitor of Apoptosis Protein hILP Undergoes Caspase-mediated Cleavage during T Lymphocyte Apoptosis

Daniel E. Johnson, Brian R. Gastman, Eva Wieckowski, Gui-Qiang Wang, Andrew Amoscato, Scott M. Delach, and Hannah Rabinowich
Cancer Res 2000 60: 1818-1823. [Abstract] [Full Text] [PDF]  

Identification of B94 (TNFAIP2) as a Potential Retinoic Acid Target Gene in Acute Promyelocytic Leukemia

Michael E. Rusiniak, Min Yu, Douglas T. Ross, Erin C. Tolhurst, and James L. Slack
Cancer Res 2000 60: 1824-1829. [Abstract] [Full Text] [PDF]  

Oncogenic Base Substitution Mutations in Circulating Leukocytes of Normal Individuals

Vincent L. Wilson, Xiuqin Yin, Barbara Thompson, Kerry R. Wade, Jeremy P. Watkins, Qi Wei, and William R. Lee
Cancer Res 2000 60: 1830-1834. [Abstract] [Full Text] [PDF]  

Hypermethylation of Multiple Genes in Pancreatic Adenocarcinoma

Takashi Ueki, Minoru Toyota, Taylor Sohn, Charles J. Yeo, Jean-Pierre J. Issa, Ralph H. Hruban, and Michael Goggins
Cancer Res 2000 60: 1835-1839. [Abstract] [Full Text] [PDF]  

A Splice Variant of the Neuron-restrictive Silencer Factor Repressor Is Expressed in Small Cell Lung Cancer: A Potential Role in Derepression of Neuroendocrine Genes and a Useful Clinical Marker

Judy M. Coulson, Jodie L. Edgson, Penella J. Woll, and John P. Quinn
Cancer Res 2000 60: 1840-1844. [Abstract] [Full Text] [PDF]  

Nuclear Factor-B Activation Is Involved in LMP1-mediated Transformation and Tumorigenesis of Rat-1 Fibroblasts

Zhimin He, Baozhong Xin, Xinhai Yang, Ching-ping Chan, and Liang Cao
Cancer Res 2000 60: 1845-1848. [Abstract] [Full Text] [PDF]  

Biochemistry and Biophysics:

Unrepaired Fjord Region Polycyclic Aromatic Hydrocarbon-DNA Adducts in ras Codon 61 Mutational Hot Spots

Tonko Buterin, Martin T. Hess, Natalia Luneva, Nicholas E. Geacintov, Shantu Amin, Heiko Kroth, Albrecht Seidel, and Hanspeter Naegeli
Cancer Res 2000 60: 1849-1856. [Abstract] [Full Text] [PDF]  

Carcinogenesis:

Spontaneous and Nitrosourea-induced Primary Tumors of the Central Nervous System in Fischer 344 Rats Exposed to Frequency-modulated Microwave Fields

W. Ross Adey, Craig V. Byus, Christopher D. Cain, Robert J. Higgins, Robert A. Jones, Charles J. Kean, Niels Kuster, Anne MacMurray, Robert B. Stagg, and Grenith Zimmerman
Cancer Res 2000 60: 1857-1863. [Abstract] [Full Text] [PDF]  

Chemopreventive Efficacy of Combined Piroxicam and Difluoromethylornithine Treatment of Apc Mutant Min Mouse Adenomas, and Selective Toxicity against Apc Mutant Embryos

Russell F. Jacoby, Carolyn E. Cole, Kendra Tutsch, Michael A. Newton, Gary Kelloff, Ernest T. Hawk, and Ronald A. Lubet
Cancer Res 2000 60: 1864-1870. [Abstract] [Full Text] [PDF]  

Clinical Investigations:

A Phase I Trial of the Farnesyl Transferase Inhibitor SCH66336: Evidence for Biological and Clinical Activity

Alex A. Adjei, Charles Erlichman, Jenny N. Davis, David L. Cutler, Jeff A. Sloan, Randolph S. Marks, Lorelei J. Hanson, Phyllis A. Svingen, Pamela Atherton, W. Robert Bishop, Paul Kirschmeier, and Scott H. Kaufmann
Cancer Res 2000 60: 1871-1877. [Abstract] [Full Text] [PDF]  

Experimental Therapeutics:

Antiangiogenic Scheduling of Chemotherapy Improves Efficacy against Experimental Drug-resistant Cancer

Timothy Browder, Catherine E. Butterfield, Birgit M. Kräling, Bin Shi, Blair Marshall, Michael S. O’Reilly, and Judah Folkman
Cancer Res 2000 60: 1878-1886. [Abstract] [Full Text] [PDF]  

Adenosine-mediated Killing of Cultured Epithelial Cancer Cells

Catherine P. Barry and Stuart E. Lind
Cancer Res 2000 60: 1887-1894. [Abstract] [Full Text] [PDF]  

Antileukemic Activity of Flt3 Ligand in Murine Leukemia

Abing Wang, Stephen E. Braun, Guru Sonpavde, and Kenneth Cornetta
Cancer Res 2000 60: 1895-1900. [Abstract] [Full Text] [PDF]  

Immunology:

Anthracyclines Trigger Apoptosis of Both G₀-G₁ and Cycling Peripheral Blood Lymphocytes and Induce Massive Deletion of Mature T and B Cells

Carole Ferraro, Laurence Quemeneur, Annie-France Prigent, Catherine Taverne, Jean-Pierre Revillard, and Nathalie Bonnefoy-Berard
Cancer Res 2000 60: 1901-1907. [Abstract] [Full Text] [PDF]  

Lysis of MYCN-amplified Neuroblastoma Cells by MYCN Peptide-specific Cytotoxic T Lymphocytes

Asis K. Sarkar and Jed G. Nuchtern
Cancer Res 2000 60: 1908-1913. [Abstract] [Full Text] [PDF]  

Aberrant Expression of Photoreceptor-specific Calcium-binding Protein (Recoverin) in Cancer Cell Lines

Akiko Maeda, Hiroshi Ohguro, Tadao Maeda, Ikuo Wada, Noriyuki Sato, Yoshio Kuroki, and Takashi Nakagawa
Cancer Res 2000 60: 1914-1920. [Abstract] [Full Text] [PDF]  

The Human Antimouse Immunoglobulin Response and the Anti-idiotypic Network Have No Influence on Clinical Outcome in Patients with Minimal Residual Colorectal Cancer Treated with Monoclonal Antibody CO17–1A

Rudolf Gruber, Leonardus J. M. van Haarlem, Sven O. Warnaar, Elena Holz, and Gert Riethmüller
Cancer Res 2000 60: 1921-1926. [Abstract] [Full Text] [PDF]  

Resistance to Lysis by Cytotoxic T Cells: A Dominant Effect in Metastatic Mouse Prostate Cancer Cells

Hon-Man Lee, Terry L. Timme, and Timothy C. Thompson
Cancer Res 2000 60: 1927-1933. [Abstract] [Full Text] [PDF]  

Granulocyte Macrophage Colony-stimulating Factor and Interleukin 4 Enhance the Number and Antigen-presenting Activity of Circulating CD14⁺ and CD83⁺ Cells in Cancer Patients

Michael D. Roth, Barbara J. Gitlitz, Sylvia M. Kiertscher, Alice N. Park, Marcy Mendenhall, Nancy Moldawer, and Robert A. Figlin
Cancer Res 2000 60: 1934-1941. [Abstract] [Full Text] [PDF]  

Molecular Biology and Genetics:

VHL Alterations in Human Clear Cell Renal Cell Carcinoma: Association with Advanced Tumor Stage and a Novel Hot Spot Mutation

Hiltrud Brauch, Gregor Weirich, Jürgen Brieger, Damjan Glavac, Heinz Rödl, Mariola Eichinger, Matthias Feurer, Eberhardt Weidt, Chutintorn Puranakanitstha, Christine Neuhaus, Sigmund Pomer, Walburgis Brenner, Peter Schirmacher, Stephan Störkel, Michael Rotter, Andrej Masera, Nadja Gugeler, and Hans-Joachim Decker
Cancer Res 2000 60: 1942-1948. [Abstract] [Full Text] [PDF]  

High Resolution Chromosome 3p Allelotyping of Human Lung Cancer and Preneoplastic/Preinvasive Bronchial Epithelium Reveals Multiple, Discontinuous Sites of 3p Allele Loss and Three Regions of Frequent Breakpoints

Ignacio I. Wistuba, Carmen Behrens, Arvind K. Virmani, Gina Mele, Sara Milchgrub, Luc Girard, John W. Fondon, III, Harold R. Garner, Bruce McKay, Farida Latif, Michael I. Lerman, Stephen Lam, Adi F. Gazdar, and John D. Minna
Cancer Res 2000 60: 1949-1960. [Abstract] [Full Text] [PDF]  

LRP-DIT, a Putative Endocytic Receptor Gene, Is Frequently Inactivated in Non-Small Cell Lung Cancer Cell Lines

Chun-Xiang Liu, Simone Musco, Natalia M. Lisitsina, Eva Forgacs, John D. Minna, and Nikolai A. Lisitsyn
Cancer Res 2000 60: 1961-1967. [Abstract] [Full Text] [PDF]  

Gene Amplifications Characterize Acral Melanoma and Permit the Detection of Occult Tumor Cells in the Surrounding Skin

Boris C. Bastian, Mohammed Kashani-Sabet, Henning Hamm, Tony Godfrey, Dan H. Moore, II, Eva-B. Bröcker, Philip E. LeBoit, and Dan Pinkel
Cancer Res 2000 60: 1968-1973. [Abstract] [Full Text] [PDF]  

Mutations in the XPC Gene in Families with Xeroderma Pigmentosum and Consequences at the Cell, Protein, and Transcript Levels

Franz Chavanne, Bernard C. Broughton, Daniela Pietra, Tiziana Nardo, Alison Browitt, Alan R. Lehmann, and Miria Stefanini
Cancer Res 2000 60: 1974-1982. [Abstract] [Full Text] [PDF]  

Molecular Determinants of Apoptosis Induced by the Cytotoxic Ribonuclease Onconase: Evidence for Cytotoxic Mechanisms Different from Inhibition of Protein Synthesis

Mihail S. Iordanov, Olga P. Ryabinina, John Wong, Thanh-Hoai Dinh, Dianne L. Newton, Susanna M. Rybak, and Bruce E. Magun
Cancer Res 2000 60: 1983-1994. [Abstract] [Full Text] [PDF]  

Tumor Biology:

Expression of Metallothionein II in Intestinal Metaplasia, Dysplasia, and Gastric Cancer

Matthias P. A. Ebert, Thomas Günther, Juliane Hoffmann, Jun Yu, Stephan Miehlke, Hans U. Schulz, Albert Roessner, Murray Korc, and Peter Malfertheiner
Cancer Res 2000 60: 1995-2001. [Abstract] [Full Text] [PDF]  

Loss of Expression of Dpc4 in Pancreatic Intraepithelial Neoplasia: Evidence That DPC4 Inactivation Occurs Late in Neoplastic Progression

Robb E. Wilentz, Christine A. Iacobuzio-Donahue, Pedram Argani, Denis M. McCarthy, Jennifer L. Parsons, Charles J. Yeo, Scott E. Kern, and Ralph H. Hruban
Cancer Res 2000 60: 2002-2006. [Abstract] [Full Text] [PDF]  

Insulin-like Growth Factor-I Protects Colon Cancer Cells from Death Factor-induced Apoptosis by Potentiating Tumor Necrosis Factor -induced Mitogen-activated Protein Kinase and Nuclear Factor B Signaling Pathways

Maryse M. Remacle-Bonnet, Françoise L. Garrouste, Sara Heller, Frédéric André, Jacques L. Marvaldi, and Gilbert J. Pommier
Cancer Res 2000 60: 2007-2017. [Abstract] [Full Text] [PDF]  

Detection of Hypoxia in Human Squamous Cell Carcinoma by EF5 Binding

Sydney M. Evans, Stephen Hahn, Deirdre R. Pook, W. Timothy Jenkins, Ara A. Chalian, Paul Zhang, Craig Stevens, Randall Weber, Gregory Weinstein, Ivor Benjamin, Natasha Mirza, Mark Morgan, Steven Rubin, W. Gillies McKenna, Edith M. Lord, and Cameron J. Koch
Cancer Res 2000 60: 2018-2024. [Abstract] [Full Text] [PDF]  

S-phase Arrest and Apoptosis Induced in Normal Mammary Epithelial Cells by a Novel Retinoid

Yuxiang Zhang, Arun K. Rishi, Marcia I. Dawson, Rainbow Tschang, Lulu Farhana, Madanamohan Boyanapalli, Uwe Reichert, Braham Shroot, Eric C. Van Buren, and Joseph A. Fontana
Cancer Res 2000 60: 2025-2032. [Abstract] [Full Text] [PDF]  

Fibrinogen Assembly, Secretion, and Deposition into Extracellular Matrix by MCF-7 Human Breast Carcinoma Cells

Brian J. Rybarczyk and Patricia J. Simpson-Haidaris
Cancer Res 2000 60: 2033-2039. [Abstract] [Full Text] [PDF]  

1,25-Dihydroxyvitamin D₃ and All-trans-Retinoic Acid Sensitize Breast Cancer Cells to Chemotherapy-induced Cell Death

Qin Wang, Wen Yang, Myrna S. Uytingco, Sylvia Christakos, and Robert Wieder
Cancer Res 2000 60: 2040-2048. [Abstract] [Full Text] [PDF]  

BCR-ABL Tyrosine Kinase Activity Regulates the Expression of Multiple Genes Implicated in the Pathogenesis of Chronic Myeloid Leukemia

Michael W. N. Deininger, Sara Vieira, Rezzeline Mendiola, Beate Schultheis, John M. Goldman, and Junia V. Melo
Cancer Res 2000 60: 2049-2055. [Abstract] [Full Text] [PDF]  

Glucocorticoid Receptor Gene Mutations in Leukemic Cells Acquired in Vitro and in Vivo

Andrew G. Hillmann, Jyoti Ramdas, Kirsi Multanen, Michael R. Norman, and Jeffrey M. Harmon
Cancer Res 2000 60: 2056-2062. [Abstract] [Full Text] [PDF]  

Erratum:

J. Jongsma et al., Cancer Res., 60: 741–748, 2000

Cancer Res 2000 60: 2064 [Full Text] [PDF]  

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