Advances in Brief:

A Proapoptotic Peptide for the Treatment of Solid Tumors

Jeffrey C. Mai, Zhibao Mi, Seon-Hee Kim, Bobby Ng, and Paul D. Robbins
Cancer Res 2001 61: 7709-7712. [Abstract] [Full Text] [PDF]  

Identification of a -Tubulin-binding Domain in BRCA1

Lih-Ching Hsu, Thao P. Doan, and Raymond L. White
Cancer Res 2001 61: 7713-7718. [Abstract] [Full Text] [PDF]  

Phenotypic Analysis of hMSH2 Mutations in Mouse Cells Carrying Human Chromosomes

Giancarlo Marra, Stefania D’Atri, Hai Yan, Claudia Perrera, Elda Cannavo’, Bert Vogelstein, and Josef Jiricny
Cancer Res 2001 61: 7719-7721. [Abstract] [Full Text] [PDF]  

Up-Regulation of the Ectodermal-Neural Cortex 1 (ENC1) Gene, a Downstream Target of the ß-Catenin/T-Cell Factor Complex, in Colorectal Carcinomas

Manabu Fujita, Yoichi Furukawa, Tatsuhiko Tsunoda, Toshihiro Tanaka, Michio Ogawa, and Yusuke Nakamura
Cancer Res 2001 61: 7722-7726. [Abstract] [Full Text] [PDF]  

Somatic Mutations in the DNA Damage-Response Genes ATR and CHK1 in Sporadic Stomach Tumors with Microsatellite Instability

Anna Menoyo, Hafid Alazzouzi, Eloi Espín, Manel Armengol, Hiroyuki Yamamoto, and Simó Schwartz, Jr.
Cancer Res 2001 61: 7727-7730. [Abstract] [Full Text] [PDF]  

Prognostic Impacts of Cytogenetic Findings in Clear Cell Renal Cell Carcinoma: Gain of 5q31–qter Predicts a Distinct Clinical Phenotype with Favorable Prognosis

Bastian Gunawan, Wolfgang Huber, Meike Holtrup, Anja von Heydebreck, Thomas Efferth, Annemarie Poustka, Rolf-Hermann Ringert, Gerhard Jakse, and László Füzesi
Cancer Res 2001 61: 7731-7738. [Abstract] [Full Text] [PDF]  

The Presence of Single Nucleotide Instability in Human Breast Cancer Cell Lines

Naoko Watanabe, Eriko Okochi, Masataka Mochizuki, Takashi Sugimura, and Toshikazu Ushijima
Cancer Res 2001 61: 7739-7742. [Abstract] [Full Text] [PDF]  

High Frequency of Low-Level Microsatellite Instability in Early Colorectal Cancer

Takeshi Kambara, Nagahide Matsubara, Hitoshi Nakagawa, Kenji Notohara, Takeshi Nagasaka, Tadashi Yoshino, Hiroshi Isozaki, Gerald B. Sharp, Kenji Shimizu, Jeremy Jass, and Noriaki Tanaka
Cancer Res 2001 61: 7743-7746. [Abstract] [Full Text] [PDF]  

Biochemistry and Biophysics:

Quantitative T₁ Magnetic Resonance Imaging of RIF-1 Tumors in Vivo: Detection of Early Response to Cyclophosphamide Therapy

Umamaheswar Duvvuri, Harish Poptani, Michael Feldman, Lydie Nadal-Desbarats, Michael S. Gee, William M. F. Lee, Ravinder Reddy, John S. Leigh, and Jerry D. Glickson
Cancer Res 2001 61: 7747-7753. [Abstract] [Full Text] [PDF]  

Polyamine Depletion in Human Melanoma Cells Leads to G₁ Arrest Associated with Induction of p21^{WAF1/CIP1/SDI1}, Changes in the Expression of p21-regulated Genes, and a Senescence-like Phenotype

Debora L. Kramer, Bey-Dih Chang, Ying Chen, Paula Diegelman, Kersti Alm, Adrian R. Black, Igor B. Roninson, and Carl W. Porter
Cancer Res 2001 61: 7754-7762. [Abstract] [Full Text] [PDF]  

P-Glycoprotein Does Not Reduce Substrate Concentration from the Extracellular Leaflet of the Plasma Membrane in Living Cells

Yu Chen, Alok C. Pant, and Sanford M. Simon
Cancer Res 2001 61: 7763-7769. [Abstract] [Full Text] [PDF]  

Reversal of Mitomycin C Resistance by Overexpression of Bioreductive Enzymes in Chinese Hamster Ovary Cells

Raymond P. Baumann, William F. Hodnick, Helen A. Seow, Michael F. Belcourt, Sara Rockwell, David H. Sherman, and Alan C. Sartorelli
Cancer Res 2001 61: 7770-7776. [Abstract] [Full Text] [PDF]  

Pro-oxidant and Antioxidant Mechanisms of Etoposide in HL-60 Cells: Role of Myeloperoxidase

Valerian E. Kagan, Alexander I. Kuzmenko, Yulia Y. Tyurina, Anna A. Shvedova, Tatsuya Matsura, and Jack C. Yalowich
Cancer Res 2001 61: 7777-7784. [Abstract] [Full Text] [PDF]  

Activation of Nuclear Factor B through the IKK Complex by the Topoisomerase Poisons SN38 and Doxorubicin: A Brake to Apoptosis in HeLa Human Carcinoma Cells

Virginie Bottero, Valère Busuttil, Agnès Loubat, Nicolas Magné, Jean-Louis Fischel, Gérard Milano, and Jean-François Peyron
Cancer Res 2001 61: 7785-7791. [Abstract] [Full Text] [PDF]  

Carcinogenesis:

Identification of Tumor Markers in Models of Human Colorectal Cancer Using a 19,200-Element Complementary DNA Microarray

Priti Hegde, Rong Qi, Renee Gaspard, Kristie Abernathy, Sonia Dharap, Julie Earle-Hughes, Cheryl Gay, Nnenna U. Nwokekeh, Tingan Chen, Alexander I. Saeed, Vasily Sharov, Norman H. Lee, Timothy J. Yeatman, and John Quackenbush
Cancer Res 2001 61: 7792-7797. [Abstract] [Full Text] [PDF]  

The Role of hPMS1 and hPMS2 in Predisposing to Colorectal Cancer

Tao Liu, Hai Yan, Shannon Kuismanen, Antonio Percesepe, Marie-Louise Bisgaard, Monica Pedroni, Piero Benatti, Kenneth W. Kinzler, Bert Vogelstein, Maurizio Ponz de Leon, Päivi Peltomäki, and Annika Lindblom
Cancer Res 2001 61: 7798-7802. [Abstract] [Full Text] [PDF]  

Biological Impact of Natural COOH-Terminal Deletions of Hepatitis B Virus X Protein in Hepatocellular Carcinoma Tissues

Hong Tu, Celestino Bonura, Carlo Giannini, Héléne Mouly, Patrick Soussan, Michael Kew, Patrizia Paterlini-Bréchot, Christian Bréchot, and Dina Kremsdorf
Cancer Res 2001 61: 7803-7810. [Abstract] [Full Text] [PDF]  

Clinical Investigations:

Quantitative Expression of the Human Kallikrein Gene 9 (KLK9) in Ovarian Cancer: A New Independent and Favorable Prognostic Marker

George M. Yousef, Lianna G. Kyriakopoulou, Andreas Scorilas, Stefano Fracchioli, Bruno Ghiringhello, Maryam Zarghooni, Albert Chang, Maria Diamandis, Giorgio Giardina, Warren J. Hartwick, Giovanni Richiardi, Marco Massobrio, Eleftherios P. Diamandis, and Dionyssios Katsaros
Cancer Res 2001 61: 7811-7818. [Abstract] [Full Text] [PDF]  

Epidemiology and Prevention:

-Radiation-induced G₂ Delay, Apoptosis, and p53 Response as Potential Susceptibility Markers For Lung Cancer

Hua Zhao, Margaret R. Spitz, Gail E. Tomlinson, Huifeng Zhang, John D. Minna, and Xifeng Wu
Cancer Res 2001 61: 7819-7824. [Abstract] [Full Text] [PDF]  

A Single Nucleotide Polymorphism in the Matrix Metalloproteinase-1 Promoter Enhances Lung Cancer Susceptibility

Yong Zhu, Margaret R. Spitz, Lei Lei, Gordon B. Mills, and Xifeng Wu
Cancer Res 2001 61: 7825-7829. [Abstract] [Full Text] [PDF]  

Experimental Therapeutics:

Thrombospondin-1 Type 1 Repeat Recombinant Proteins Inhibit Tumor Growth through Transforming Growth Factor-ß-dependent and -independent Mechanisms

Wei-Min Miao, Wen Lin Seng, Mark Duquette, Patrick Lawler, Christiane Laus, and Jack Lawler
Cancer Res 2001 61: 7830-7839. [Abstract] [Full Text] [PDF]  

sFlt-1 Gene-transfected Fibroblasts: A Wound-specific Gene Therapy Inhibits Local Cancer Recurrence

Weige Yang, Shigeki Arii, Akira Mori, Katsuyoshi Furumoto, Teizou Nakao, Naoki Isobe, Toru Murata, Hisashi Onodera, and Masayuki Imamura
Cancer Res 2001 61: 7840-7845. [Abstract] [Full Text] [PDF]  

Antiangiogenic Therapy of Established Tumors in Human Skin/Severe Combined Immunodeficiency Mouse Chimeras by Anti-Endoglin (CD105) Monoclonal Antibodies, and Synergy between Anti-Endoglin Antibody and Cyclophosphamide

Norihiko Takahashi, Akinao Haba, Fumihiko Matsuno, and Ben K. Seon
Cancer Res 2001 61: 7846-7854. [Abstract] [Full Text] [PDF]  

Antisense-mediated Suppression of Human Heparanase Gene Expression Inhibits Pleural Dissemination of Human Cancer Cells

Futoshi Uno, Toshiyoshi Fujiwara, Yoshiko Takata, Shoichiro Ohtani, Kou Katsuda, Munenori Takaoka, Takaomi Ohkawa, Yoshio Naomoto, Motowo Nakajima, and Noriaki Tanaka
Cancer Res 2001 61: 7855-7860. [Abstract] [Full Text] [PDF]  

Eradication of Established Tumors by Vaccination with Venezuelan Equine Encephalitis Virus Replicon Particles Delivering Human Papillomavirus 16 E7 RNA

Markwin P. Velders, Sue McElhiney, Maria Cristina Cassetti, Gretchen L. Eiben, Terry Higgins, Gerald R. Kovacs, Amira G. Elmishad, W. Martin Kast, and Larry R. Smith
Cancer Res 2001 61: 7861-7867. [Abstract] [Full Text] [PDF]  

Therapeutic Efficacy of Aortic Administration of N-Acetylcysteine as a Chemoprotectant against Bone Marrow Toxicity after Intracarotid Administration of Alkylators, with or without Glutathione Depletion in a Rat Model

Edward A. Neuwelt, Michael A. Pagel, Brant P. Hasler, Thomas G. Deloughery, and Leslie L. Muldoon
Cancer Res 2001 61: 7868-7874. [Abstract] [Full Text] [PDF]  

Prevention and Inhibition of Nasopharyngeal Carcinoma Growth by Antiviral Phosphonated Nucleoside Analogs

Shigeyuki Murono, Nancy Raab-Traub, and Joseph S. Pagano
Cancer Res 2001 61: 7875-7877. [Abstract] [Full Text] [PDF]  

Expression of Clostridium Perfringens Enterotoxin Receptors Claudin-3 and Claudin-4 in Prostate Cancer Epithelium

Haiyan Long, Colin D. Crean, Wei-Hua Lee, O. William Cummings, and Theodore G. Gabig
Cancer Res 2001 61: 7878-7881. [Abstract] [Full Text] [PDF]  

A Midkine Promoter-based Conditionally Replicative Adenovirus for Treatment of Pediatric Solid Tumors and Bone Marrow Tumor Purging

Yasuo Adachi, Paul N. Reynolds, Masato Yamamoto, Minghui Wang, Koichi Takayama, Shyuichiro Matsubara, Takashi Muramatsu, and David T. Curiel
Cancer Res 2001 61: 7882-7888. [Abstract] [Full Text] [PDF]  

Immunology:

Evidence for an Antigen-driven Humoral Immune Response in Medullary Ductal Breast Cancer

J. A. Coronella, P. Telleman, G. A. Kingsbury, T. D. Truong, S. Hays, and R. P. Junghans
Cancer Res 2001 61: 7889-7899. [Abstract] [Full Text] [PDF]  

Tumor Antigens Isolated from a Patient with Vitiligo and T-Cell-infiltrated Melanoma

Yukiko Kiniwa, Tomonobu Fujita, Masanori Akada, Keiichi Ito, Tomoko Shofuda, Yuriko Suzuki, Akifumi Yamamoto, Toshiaki Saida, and Yutaka Kawakami
Cancer Res 2001 61: 7900-7907. [Abstract] [Full Text] [PDF]  

Proteomics-based Identification of Protein Gene Product 9.5 as a Tumor Antigen That Induces a Humoral Immune Response in Lung Cancer

Franck Brichory, David Beer, Francois LeNaour, Thomas Giordano, and Samir Hanash
Cancer Res 2001 61: 7908-7912. [Abstract] [Full Text] [PDF]  

Efficient Antigen Gene Transduction Using Arg-Gly-Asp Fiber-Mutant Adenovirus Vectors Can Potentiate Antitumor Vaccine Efficacy and Maturation of Murine Dendritic Cells

Naoki Okada, Tomomi Saito, Yasushige Masunaga, Yukiko Tsukada, Shinsaku Nakagawa, Hiroyuki Mizuguchi, Kohei Mori, Yuka Okada, Takuya Fujita, Takao Hayakawa, Tadanori Mayumi, and Akira Yamamoto
Cancer Res 2001 61: 7913-7919. [Abstract] [Full Text] [PDF]  

Immunization against Endogenous Retroviral Tumor-associated Antigens

Michael H. Kershaw, Cary Hsu, Wallace Mondesire, Libbie L. Parker, Gang Wang, Willem W. Overwijk, Rejean Lapointe, James C. Yang, Rong-Fu Wang, Nicholas P. Restifo, and Patrick Hwu
Cancer Res 2001 61: 7920-7924. [Abstract] [Full Text] [PDF]  

Molecular Biology and Genetics:

Induction of G250-targeted and T-Cell-mediated Antitumor Activity against Renal Cell Carcinoma Using a Chimeric Fusion Protein Consisting of G250 and Granulocyte/Monocyte-Colony Stimulating Factor

Cho-Lea Tso, Amnon Zisman, Allan Pantuck, Randy Calilliw, Jose M. Hernandez, Sun Paik, David Nguyen, Barbara Gitlitz, Peter I. Shintaku, Jean de Kernion, Robert Figlin, and Arie Belldegrun
Cancer Res 2001 61: 7925-7933. [Abstract] [Full Text] [PDF]  

The Distinct Spectra of Tumor-associated Apc Mutations in Mismatch Repair-deficient Apc^1638N Mice Define the Roles of MSH3 and MSH6 in DNA Repair and Intestinal Tumorigenesis

Mari Kuraguchi, Kan Yang, Edmund Wong, Elena Avdievich, Kunhua Fan, Richard D. Kolodner, Martin Lipkin, Anthony M. C. Brown, Raju Kucherlapati, and Winfried Edelmann
Cancer Res 2001 61: 7934-7942. [Abstract] [Full Text] [PDF]  

Inactivation of Human SRBC, Located within the 11p15.5-p15.4 Tumor Suppressor Region, in Breast and Lung Cancers

Xie L. Xu, Leeju C. Wu, Fenghe Du, Arthur Davis, Michael Peyton, Yoshio Tomizawa, Anirban Maitra, Gail Tomlinson, Adi F. Gazdar, Bernard E. Weissman, Anne M. Bowcock, Richard Baer, and John D. Minna
Cancer Res 2001 61: 7943-7949. [Abstract] [Full Text] [PDF]  

Accumulation of Losses of Heterozygosity and Multistep Carcinogenesis in Pulmonary Adenocarcinoma

Yasuyuki Aoyagi, Tomoyuki Yokose, Yuko Minami, Atsushi Ochiai, Tatsuo Iijima, Yukio Morishita, Tatsuya Oda, Katashi Fukao, and Masayuki Noguchi
Cancer Res 2001 61: 7950-7954. [Abstract] [Full Text] [PDF]  

Absence of Genetic Abnormalities in Fibroadenomas of the Breast Determined at p53 Gene Mutations and Microsatellite Alterations

Noreli Franco, Samy-Félix Picard, Florence Mege, Laurent Arnould, and Sarab Lizard-Nacol
Cancer Res 2001 61: 7955-7958. [Abstract] [Full Text] [PDF]  

Tumor Biology:

Activation of Melanoma Antigen Tumor Antigens Occurs Early in Lung Carcinogenesis

Se J. Jang, Jean-Charles Soria, Luo Wang, Khaled A. Hassan, Rodolfo C. Morice, Garrett L. Walsh, Waun Ki Hong, and Li Mao
Cancer Res 2001 61: 7959-7963. [Abstract] [Full Text] [PDF]  

Urea as a Recovery Marker for Quantitative Assessment of Tumor Interstitial Solutes with Microdialysis

Susan N. Ettinger, Christiane C. Poellmann, Natalie A. Wisniewski, Amanda A. Gaskin, Jennifer S. Shoemaker, Jean M. Poulson, Mark W. Dewhirst, and Bruce Klitzman
Cancer Res 2001 61: 7964-7970. [Abstract] [Full Text] [PDF]  

Fluorodeoxyuridine Improves Imaging of Human Glioblastoma Xenografts with Radiolabeled Iododeoxyuridine

Yves M. Dupertuis, Maria Vazquez, Jean-Pierre Mach, Nicolas De Tribolet, Claude Pichard, Daniel O. Slosman, and Franz Buchegger
Cancer Res 2001 61: 7971-7977. [Abstract] [Full Text] [PDF]  

Human APC2 Localization and Allelic Imbalance

Christy Rothwell Jarrett, Jan Blancato, Tin Cao, D. S. Bressette, M. Cepeda, Paul E. Young, C. Richter King, and Stephen W. Byers
Cancer Res 2001 61: 7978-7984. [Abstract] [Full Text] [PDF]  

Expression of Dominant-negative Form of Ets-1 Suppresses Fibronectin-stimulated Cell Adhesion and Migration Through Down-Regulation of Integrin 5 Expression in U251 Glioma Cell Line

Daisuke Kita, Takahisa Takino, Mitsutoshi Nakada, Tomoya Takahashi, Junkoh Yamashita, and Hiroshi Sato
Cancer Res 2001 61: 7985-7991. [Abstract] [Full Text] [PDF]  

Expression of Hypoxia-inducible Carbonic Anhydrase-9 Relates to Angiogenic Pathways and Independently to Poor Outcome in Non-Small Cell Lung Cancer

Alexandra Giatromanolaki, Michael I. Koukourakis, Efthimios Sivridis, Jaromir Pastorek, Charles C. Wykoff, Kevin C. Gatter, and Adrian L. Harris
Cancer Res 2001 61: 7992-7998. [Abstract] [Full Text] [PDF]  

Diminished Expression of S100A2, a Putative Tumor Suppressor, at Early Stage of Human Lung Carcinogenesis

Gang Feng, Xiao-chun Xu, Emile M. Youssef, and Reuben Lotan
Cancer Res 2001 61: 7999-8004. [Abstract] [Full Text] [PDF]  

Direct Relation between BCR-ABL Tyrosine Kinase Activity and Cyclin D2 Expression in Lymphoblasts

Michael W. N. Deininger, Sara A. D. Vieira, Yelena Parada, Lolita Banerji, Eric W-F. Lam, Gordon Peters, François-Xavier Mahon, Thomas Köhler, John M. Goldman, and Junia V. Melo
Cancer Res 2001 61: 8005-8013. [Abstract] [Full Text] [PDF]  

CpG Methylation as a Basis for Breast Tumor-specific Loss of NES1/Kallikrein 10 Expression

Biao Li, Jaya Goyal, Sanjay Dhar, Goberdhan Dimri, Ella Evron, Saraswati Sukumar, David E. Wazer, and Vimla Band
Cancer Res 2001 61: 8014-8021. [Abstract] [Full Text] [PDF]  

Altered Gene Expression Pattern in Cultured Human Breast Cancer Cells Treated with Hepatocyte Growth Factor/Scatter Factor in the Setting of DNA Damage

Ren-qi Yuan, Saijun Fan, Mohan Achary, Donn M. Stewart, Itzhak D. Goldberg, and Eliot M. Rosen
Cancer Res 2001 61: 8022-8031. [Abstract] [Full Text] [PDF]  

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Announcements

Cancer Res 2001 61: 8032 [Full Text] [PDF]  

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