Advances in Brief:

Inhibition of Histone Deacetylase Activity by Trichostatin A Modulates Gene Expression during Mouse Embryogenesis without Apparent Toxicity

Clara Nervi, Ugo Borello, Francesco Fazi, Viviana Buffa, Pier Giuseppe Pelicci, and Giulio Cossu
Cancer Res 2001 61: 1247-1249. [Abstract] [Full Text] [PDF]  

The ZNF217 Gene Amplified in Breast Cancers Promotes Immortalization of Human Mammary Epithelial Cells

Genevieve H. Nonet, Martha R. Stampfer, Koei Chin, Joe W. Gray, Colin C. Collins, and Paul Yaswen
Cancer Res 2001 61: 1250-1254. [Abstract] [Full Text] [PDF]  

The Effects of Angiopoietin-1 and -2 on Tumor Growth and Angiogenesis in Human Colon Cancer

Syed A. Ahmad, Wenbiao Liu, Young D. Jung, Fan Fan, Michael Wilson, Niels Reinmuth, Raymond M. Shaheen, Corazon D. Bucana, and Lee M. Ellis
Cancer Res 2001 61: 1255-1259. [Abstract] [Full Text] [PDF]  

Apoptosis Induction by the Photosensitizer Verteporfin: Identification of Mitochondrial Adenine Nucleotide Translocator as a Critical Target

Anne-Sophie Belzacq, Etienne Jacotot, Helena L. A. Vieira, Dominique Mistro, David J. Granville, Zhihua Xie, John C. Reed, Guido Kroemer, and Catherine Brenner
Cancer Res 2001 61: 1260-1264. [Abstract] [Full Text] [PDF]  

The Fibroblast Growth Factor Receptor 3 (FGFR3) Mutation Is a Strong Indicator of Superficial Bladder Cancer with Low Recurrence Rate

Bas W. G. van Rhijn, Irene Lurkin, François Radvanyi, Wim J. Kirkels, Theodorus H. van der Kwast, and Ellen C. Zwarthoff
Cancer Res 2001 61: 1265-1268. [Abstract] [Full Text] [PDF]  

Age-associated Risk of Cancer among Individuals with N-Acetyltransferase 2 (NAT2) Mutations and Mutations in DNA Mismatch Repair Genes

Marsha L. Frazier, Frederick T. O’Donnell, Shouming Kong, Xiangjun Gu, Imelda Campos, Rajyalakshmi Luthra, Patrick M. Lynch, and Christopher I. Amos
Cancer Res 2001 61: 1269-1271. [Abstract] [Full Text] [PDF]  

Hydroxamate-Type Matrix Metalloproteinase Inhibitor Batimastat Promotes Liver Metastasis

Achim Krüger, Rita Soeltl, Igor Sopov, Charlotte Kopitz, Matthias Arlt, Viktor Magdolen, Nadia Harbeck, Bernd Gänsbacher, and Manfred Schmitt
Cancer Res 2001 61: 1272-1275. [Abstract] [Full Text] [PDF]  

Coexpression of the Partial Androgen Receptor Enhances the Efficacy of Prostate-specific Antigen Promoter-driven Suicide Gene Therapy for Prostate Cancer Cells at Low Testosterone Concentrations

Satoshi Suzuki, Takushi Tadakuma, Tomohiko Asano, and Masamichi Hayakawa
Cancer Res 2001 61: 1276-1279. [Abstract] [Full Text] [PDF]  

CEP1612, a Dipeptidyl Proteasome Inhibitor, Induces p21^WAF1 and p27^KIP1 Expression and Apoptosis and Inhibits the Growth of the Human Lung Adenocarcinoma A-549 in Nude Mice

Jiazhi Sun, Sangkil Nam, Chang-Sun Lee, Benyi Li, Domenico Coppola, Andrew D. Hamilton, Q. Ping Dou, and Saïd M. Sebti
Cancer Res 2001 61: 1280-1284. [Abstract] [Full Text] [PDF]  

Cytokine Gene Expression in Neoplastic B Cells from Human Mantle Cell, Follicular, and Marginal Zone Lymphomas and in Their Postulated Normal Counterparts

Irma Airoldi, Roberta Guglielmino, Fabio Ghiotto, Anna Corcione, Paola Facchetti, Mauro Truini, and Vito Pistoia
Cancer Res 2001 61: 1285-1290. [Abstract] [Full Text] [PDF]  

Ovarian Epithelial Cell Lineage-specific Gene Expression Using the Promoter of a Retrovirus-like Element

Muthu Selvakumaran, Rudi Bao, Anne P. G. Crijns, Denise C. Connolly, Jillian K. Weinstein, and Thomas C. Hamilton
Cancer Res 2001 61: 1291-1295. [Abstract] [Full Text] [PDF]  

Invasiveness of Cutaneous Malignant Melanoma Is Influenced by Matrix Metalloproteinase 1 Gene Polymorphism

Shu Ye, Sahar Dhillon, Steven J. Turner, Adrian C. Bateman, Jeffrey M. Theaker, Ruth M. Pickering, Ian Day, and W. Martin Howell
Cancer Res 2001 61: 1296-1298. [Abstract] [Full Text] [PDF]  

Detection of Mitochondrial DNA Mutations in Pancreatic Cancer Offers a "Mass"-ive Advantage over Detection of Nuclear DNA Mutations

Jessa B. Jones, Jason J. Song, Paula M. Hempen, Giovanni Parmigiani, Ralph H. Hruban, and Scott E. Kern
Cancer Res 2001 61: 1299-1304. [Abstract] [Full Text] [PDF]  

Epistatic Interactions between Skin Tumor Modifier Loci in Interspecific (spretus/musculus) Backcross Mice

Hiroki Nagase, Jian-Hua Mao, John P. de Koning, Tomoe Minami, and Allan Balmain
Cancer Res 2001 61: 1305-1308. [Abstract] [Full Text] [PDF]  

Chromosomal Alterations in Lung Adenocarcinoma from Smokers and Nonsmokers

Montserrat Sanchez-Cespedes, Steven A. Ahrendt, Steven Piantadosi, Rafael Rosell, Maria Monzo, Li Wu, William H. Westra, Steven C. Yang, Jin Jen, and David Sidransky
Cancer Res 2001 61: 1309-1313. [Abstract] [Full Text] [PDF]  

Resistance to Tumor Necrosis Factor-related Apoptosis-inducing Ligand-induced Apoptosis in Neuroblastoma Cells Correlates with a Loss of Caspase-8 Expression

Angelika Eggert, Michael A. Grotzer, Tycho J. Zuzak, Barbara R. Wiewrodt, Ruth Ho, Naohiko Ikegaki, and Garrett M. Brodeur
Cancer Res 2001 61: 1314-1319. [Abstract] [Full Text] [PDF]  

Breast Stroma Plays a Dominant Regulatory Role in Breast Epithelial Growth and Differentiation: Implications for Tumor Development and Progression

Malathy P. V. Shekhar, Jill Werdell, Steve J. Santner, Robert J. Pauley, and Larry Tait
Cancer Res 2001 61: 1320-1326. [Abstract] [Full Text] [PDF]  

DNA Methyltransferase Inhibition Enhances Apoptosis Induced by Histone Deacetylase Inhibitors

Wei-Guo Zhu, Romola R. Lakshmanan, Matthew D. Beal, and Gregory A. Otterson
Cancer Res 2001 61: 1327-1333. [Abstract] [Full Text] [PDF]  

Global Effects of Anchorage on Gene Expression during Mammary Carcinoma Cell Growth Reveal Role of Tumor Necrosis Factor-related Apoptosis-inducing Ligand in Anoikis

Gary S. Goldberg, Zhaoyu Jin, Hitoshi Ichikawa, Akihiro Naito, Misao Ohki, Wafik S. El-Deiry, and Hiroyuki Tsuda
Cancer Res 2001 61: 1334-1337. [Abstract] [Full Text] [PDF]  

Down-Regulation of Promoter I.3 Activity of the Human Aromatase Gene in Breast Tissue by Zinc-finger Protein, Snail (SnaH)

Tomoharu Okubo, Thong K. Truong, Bin Yu, Toru Itoh, Jin Zhao, Baiba Grube, Dujin Zhou, and Shiuan Chen
Cancer Res 2001 61: 1338-1346. [Abstract] [Full Text] [PDF]  

Phosphorylation- and SKP1-independent in Vitro Ubiquitination of E2F1 by Multiple ROC-Cullin Ligases

Tomohiko Ohta and Yue Xiong
Cancer Res 2001 61: 1347-1353. [Abstract] [Full Text] [PDF]  

Modulation of Nucleotide Excision Repair Capacity by XPD Polymorphisms in Lung Cancer Patients

Margaret R. Spitz, Xifeng Wu, Yunfei Wang, Li-E Wang, Sanjay Shete, Christopher I. Amos, Zhaozheng Guo, Lei Lei, Harvey Mohrenweiser, and Qingyi Wei
Cancer Res 2001 61: 1354-1357. [Abstract] [Full Text] [PDF]  

Erythropoietin Restores the Anemia-induced Reduction in Cyclophosphamide Cytotoxicity in Rat Tumors

Oliver Thews, Debra K. Kelleher, and Peter Vaupel
Cancer Res 2001 61: 1358-1361. [Abstract] [Full Text] [PDF]  

Biochemistry and Biophysics:

Altered Profiles in Nuclear Matrix Proteins Associated with DNA in Situ during Progression of Breast Cancer Cells

Virginia A. Spencer, Shanti K. Samuel, and James R. Davie
Cancer Res 2001 61: 1362-1366. [Abstract] [Full Text] [PDF]  

Up-Regulation of Urokinase-Type Plasminogen Activator by Insulin-like Growth Factor-I Depends upon Phosphatidylinositol-3 Kinase and Mitogen-activated Protein Kinase Kinase

Sandra E. Dunn, Johann V. Torres, Jennifer S. Oh, David M. Cykert, and J. Carl Barrett
Cancer Res 2001 61: 1367-1374. [Abstract] [Full Text] [PDF]  

Carcinogenesis:

Elevated Protein Kinase C ßII Is an Early Promotive Event in Colon Carcinogenesis

Yesim Gökmen-Polar, Nicole R. Murray, Marco A. Velasco, Zoran Gatalica, and Alan P. Fields
Cancer Res 2001 61: 1375-1381. [Abstract] [Full Text] [PDF]  

Frequent Mutations of Fas Gene in Thyroid Lymphoma

Tetsuya Takakuwa, Zhiming Dong, Hitoshi Takayama, Fumio Matsuzuka, Shigekazu Nagata, and Katsuyuki Aozasa
Cancer Res 2001 61: 1382-1385. [Abstract] [Full Text] [PDF]  

Suppression of Tumor Cell Growth Both in Nude Mice and in Culture by n-3 Polyunsaturated Fatty Acids: Mediation through Cyclooxygenase-independent Pathways

Mary D. Boudreau, Kyung Hee Sohn, Sang Hoon Rhee, Sam W. Lee, Jay D. Hunt, and Daniel H. Hwang
Cancer Res 2001 61: 1386-1391. [Abstract] [Full Text] [PDF]  

Involvement of Mammalian MLH1 in the Apoptotic Response to Peroxide-induced Oxidative Stress

Rebecca A. Hardman, Cynthia A. Afshari, and J. Carl Barrett
Cancer Res 2001 61: 1392-1397. [Abstract] [Full Text] [PDF]  

Crkl Enhances Leukemogenesis in BCR/ABL P190 Transgenic Mice

Bianca Hemmeryckx, Arnoud van Wijk, Anja Reichert, Vesa Kaartinen, Ron de Jong, Paul K. Pattengale, Ignacio Gonzalez-Gomez, John Groffen, and Nora Heisterkamp
Cancer Res 2001 61: 1398-1405. [Abstract] [Full Text] [PDF]  

Clinical Investigations:

Increased Gastric Epithelial Cell Apoptosis Associated with Colonization with cagA+ Helicobacter pylori Strains

Steven F. Moss, Emilia Mia Sordillo, Abdalrahman M. Abdalla, Vladimir Makarov, Zoltan Hanzely, Guillermo I. Perez-Perez, Martin J. Blaser, and Peter R. Holt
Cancer Res 2001 61: 1406-1411. [Abstract] [Full Text] [PDF]  

P-Glycoprotein and Multidrug Resistance-related Protein Expressions in Relation to Technetium-99m Methoxyisobutylisonitrile Scintimammography Findings

Chia-Hung Kao, Shih-Chuan Tsai, Tse-Jia Liu, Yung-Jen Ho, Jhi-Joung Wang, Shung-Tai Ho, and Sheng-Ping ChangLai
Cancer Res 2001 61: 1412-1414. [Abstract] [Full Text] [PDF]  

The COOH-Terminal Src Kinase Csk Is a Tumor Antigen in Human Carcinoma

Christine Bénistant, Jean-François Bourgaux, Heliette Chapuis, Nicolas Mottet, Serge Roche, and Jean-Pierre Bali
Cancer Res 2001 61: 1415-1420. [Abstract] [Full Text] [PDF]  

Thymidine Kinase and Thymidylate Synthase in Advanced Breast Cancer: Response to Tamoxifen and Chemotherapy

John A. Foekens, Sylvie Romain, Maxime P. Look, Pierre-Marie Martin, and Jan G. M. Klijn
Cancer Res 2001 61: 1421-1425. [Abstract] [Full Text] [PDF]  

Endocrinology:

Increased in Vivo Phosphorylation of Ret Tyrosine 1062 Is a Potential Pathogenetic Mechanism of Multiple Endocrine Neoplasia Type 2B

Domenico Salvatore, Rosa Marina Melillo, Carmen Monaco, Roberta Visconti, Gianfranco Fenzi, Giancarlo Vecchio, Alfredo Fusco, and Massimo Santoro
Cancer Res 2001 61: 1426-1431. [Abstract] [Full Text] [PDF]  

Role of the Central Melanocortin System in Cachexia

Daniel L. Marks, Nicholas Ling, and Roger D. Cone
Cancer Res 2001 61: 1432-1438. [Abstract] [Full Text] [PDF]  

Vitamin D Is a Prooxidant in Breast Cancer Cells

Ruth Koren, Irit Hadari-Naor, Efrat Zuck, Carmela Rotem, Uri A. Liberman, and Amiram Ravid
Cancer Res 2001 61: 1439-1444. [Abstract] [Full Text] [PDF]  

Epidemiology and Prevention:

Sensitivity to DNA Damage Induced by Benzo(a)pyrene Diol Epoxide and Risk of Lung Cancer: A Case-Control Analysis

Donghui Li, Pervez F. Firozi, Li-E Wang, Carol H. Bosken, Margaret R. Spitz, Waun Ki Hong, and Qingyi Wei
Cancer Res 2001 61: 1445-1450. [Abstract] [Full Text] [PDF]  

Increased Expression of Cyclooxygenase-2 Protein in 4-Nitroquinoline-1-oxide-induced Rat Tongue Carcinomas and Chemopreventive Efficacy of a Specific Inhibitor, Nimesulide

Hiroshi Shiotani, Ayumi Denda, Kazuhiko Yamamoto, Wakashi Kitayama, Takehiro Endoh, Yasutaka Sasaki, Masahiro Tsutsumi, Masahito Sugimura, and Yoichi Konishi
Cancer Res 2001 61: 1451-1456. [Abstract] [Full Text] [PDF]  

Randomized Trial of Supplemental ß-Carotene to Prevent Second Head and Neck Cancer

Susan T. Mayne, Brenda Cartmel, Marianna Baum, Gail Shor-Posner, Barbara G. Fallon, Kenneth Briskin, Judy Bean, Tongzhang Zheng, Dennis Cooper, Craig Friedman, and W. Jarrard Goodwin, Jr.
Cancer Res 2001 61: 1457-1463. [Abstract] [Full Text] [PDF]  

Experimental Therapeutics:

Tyrosine Kinase Inhibition of Multiple Angiogenic Growth Factor Receptors Improves Survival in Mice Bearing Colon Cancer Liver Metastases by Inhibition of Endothelial Cell Survival Mechanisms

Raymond M. Shaheen, William W. Tseng, Darren W. Davis, Wenbiao Liu, Niels Reinmuth, Roberto Vellagas, Andrew A. Wieczorek, Yasuhiro Ogura, David J. McConkey, Kenneth E. Drazan, Corazon D. Bucana, Gerald McMahon, and Lee M. Ellis
Cancer Res 2001 61: 1464-1468. [Abstract] [Full Text] [PDF]  

The Pharmacological Phenotype of Combined Multidrug-Resistance mdr1a/1b- and mrp1-deficient Mice

Dennis R. Johnson, Rick A. Finch, Z. Ping Lin, Caroline J. Zeiss, and Alan C. Sartorelli
Cancer Res 2001 61: 1469-1476. [Abstract] [Full Text] [PDF]  

Combination of Phenylbutyrate and 13-cis Retinoic Acid Inhibits Prostate Tumor Growth and Angiogenesis

Roberto Pili, Mark P. Kruszewski, Brant W. Hager, Julie Lantz, and Michael A. Carducci
Cancer Res 2001 61: 1477-1485. [Abstract] [Full Text] [PDF]  

Identification and Characterization of A-105972, an Antineoplastic Agent

Jinshyun R. Wu-Wong, Jeffery D. Alder, Lisa Alder, David J. Burns, Edward K-H. Han, Bruce Credo, Stephen K. Tahir, Brian D. Dayton, Patricia J. Ewing, and William J. Chiou
Cancer Res 2001 61: 1486-1492. [Abstract] [Full Text] [PDF]  

Pharmacological Inhibition of Fatty Acid Synthase Activity Produces Both Cytostatic and Cytotoxic Effects Modulated by p53

Ji-Nong Li, Myriam Gorospe, Francis J. Chrest, Tirukalikundram S. Kumaravel, Michele K. Evans, Wan Fang Han, and Ellen S. Pizer
Cancer Res 2001 61: 1493-1499. [Abstract] [Full Text] [PDF]  

The Level of MHC Class I Expression on Murine Adenocarcinoma Can Change the Antitumor Effector Mechanism of Immunocytokine Therapy

Michael Imboden, Kristopher R. Murphy, Alexander L. Rakhmilevich, Zane C. Neal, Rong Xiang, Ralph A. Reisfeld, Stephen D. Gillies, and Paul M. Sondel
Cancer Res 2001 61: 1500-1507. [Abstract] [Full Text] [PDF]  

p53 Modulates the Effect of Loss of DNA Mismatch Repair on the Sensitivity of Human Colon Cancer Cells to the Cytotoxic and Mutagenic Effects of Cisplatin

Xinjian Lin, Krishnan Ramamurthi, Misako Mishima, Akira Kondo, Randolph D. Christen, and Stephen B. Howell
Cancer Res 2001 61: 1508-1516. [Abstract] [Full Text] [PDF]  

Interferon-inducible Protein 10 Induction and Inhibition of Angiogenesis in Vivo by the Antitumor Agent 5,6-Dimethylxanthenone-4-acetic Acid (DMXAA)

Zhihui Cao, Bruce C Baguley, and Lai-Ming Ching
Cancer Res 2001 61: 1517-1521. [Abstract] [Full Text] [PDF]  

Methotrexate Accumulates to Similar Levels in Animals Transplanted with Normal versus Drug-resistant Transgenic Marrow

Lalitha R. Belur, Debra Boelk-Galvan, Miechaleen D. Diers, R. Scott McIvor, and Cheryl L. Zimmerman
Cancer Res 2001 61: 1522-1526. [Abstract] [Full Text] [PDF]  

Antitumor Activity of the Rapamycin Analog CCI-779 in Human Primitive Neuroectodermal Tumor/Medulloblastoma Models as Single Agent and in Combination Chemotherapy

Birgit Geoerger, Karol Kerr, Cheng-Bi Tang, Kar-Ming Fung, Bruce Powell, Leslie N. Sutton, Peter C. Phillips, and Anna J. Janss
Cancer Res 2001 61: 1527-1532. [Abstract] [Full Text] [PDF]  

Inhibition of Extracellular Signal-regulated Kinase (ERK) Mediates Cell Cycle Phase Independent Apoptosis in Vinblastine-treated ML-1 Cells

Terrance A. Stadheim, Helen Xiao, and Alan Eastman
Cancer Res 2001 61: 1533-1540. [Abstract] [Full Text] [PDF]  

Inhibition of Extracellular Signal-regulated Kinase 1/2 Phosphorylation and Induction of Apoptosis by Sulindac Metabolites

Pamela L. Rice, Ryan J. Goldberg, Evan C. Ray, Linda J. Driggers, and Dennis J. Ahnen
Cancer Res 2001 61: 1541-1547. [Abstract] [Full Text] [PDF]  

Targeting a Genetically Engineered Elastin-like Polypeptide to Solid Tumors by Local Hyperthermia

Dan E. Meyer, Garheng A. Kong, Mark W. Dewhirst, Michael R. Zalutsky, and Ashutosh Chilkoti
Cancer Res 2001 61: 1548-1554. [Abstract] [Full Text] [PDF]  

Antibodies Elicited by Naked DNA Vaccination against the Complementary-determining Region 3 Hypervariable Region of Immunoglobulin Heavy Chain Idiotypic Determinants of B-lymphoproliferative Disorders Specifically React with Patients’ Tumor Cells

Monica Rinaldi, Francesco Ria, Paola Parrella, Emanuela Signori, Anna Serra, Silvia A. Ciafrè, Isabella Vespignani, Marzia Lazzari, Maria Giulia Farace, Giuseppe Saglio, and Vito M. Fazio
Cancer Res 2001 61: 1555-1562. [Abstract] [Full Text] [PDF]  

Molecular Biology and Genetics:

Identification and Characterization of Prostein, a Novel Prostate-specific Protein

Jiangchun Xu, Michael Kalos, John A. Stolk, Eden J. Zasloff, Xinqun Zhang, Raymond L. Houghton, Aristides Maltez Filho, Marcos Nolasco, Roberto Badaró, and Steven G. Reed
Cancer Res 2001 61: 1563-1568. [Abstract] [Full Text] [PDF]  

Gene Expression Patterns Associated with the Metastatic Phenotype in Rodent and Human Tumors

Andrea Nestl, Oliver D. Von Stein, Kurt Zatloukal, Wolf-Gerolf Thies, Peter Herrlich, Martin Hofmann, and Jonathan P. Sleeman
Cancer Res 2001 61: 1569-1577. [Abstract] [Full Text] [PDF]  

Effect of Adenoviral Transduction of the Fragile Histidine Triad Gene into Esophageal Cancer Cells

Hideshi Ishii, Kristoffel R. Dumon, Andrea Vecchione, Francesco Trapasso, Koshi Mimori, Hansjuerg Alder, Masaki Mori, Gabriella Sozzi, Raffaele Baffa, Kay Huebner, and Carlo M. Croce
Cancer Res 2001 61: 1578-1584. [Abstract] [Full Text] [PDF]  

End-joining Deficiency and Radiosensitization Induced by Gemcitabine

John W. G. van Putten, Harry J. M. Groen, Kees Smid, Godefridus J. Peters, and Harm H. Kampinga
Cancer Res 2001 61: 1585-1591. [Abstract] [Full Text] [PDF]  

Transcriptional Activation of the Human HMG1 Gene in Cisplatin-resistant Human Cancer Cells

Gunji Nagatani, Minoru Nomoto, Hiroshi Takano, Tomoko Ise, Ken Kato, Toshihiro Imamura, Hiroto Izumi, Kazumi Makishima, and Kimitoshi Kohno
Cancer Res 2001 61: 1592-1597. [Abstract] [Full Text] [PDF]  

A Possible Role of p73 on the Modulation of p53 Level through MDM2

Xiao Qi Wang, Weg M. Ongkeko, Anita W. S. Lau, Ka Man Leung, and Randy Y. C. Poon
Cancer Res 2001 61: 1598-1603. [Abstract] [Full Text] [PDF]  

Resveratrol-induced Activation of p53 and Apoptosis Is Mediated by Extracellular- Signal-regulated Protein Kinases and p38 Kinase

Qing-Bai She, Ann M. Bode, Wei-Ya Ma, Nan-Yue Chen, and Zigang Dong
Cancer Res 2001 61: 1604-1610. [Abstract] [Full Text] [PDF]  

Prostate Short-Chain Dehydrogenase Reductase 1 (PSDR1): A New Member of the Short-Chain Steroid Dehydrogenase/Reductase Family Highly Expressed in Normal and Neoplastic Prostate Epithelium

Biaoyang Lin, James T. White, Camari Ferguson, Shunyou Wang, Robert Vessella, Roger Bumgarner, Lawrence D. True, Leroy Hood, and Peter S. Nelson
Cancer Res 2001 61: 1611-1618. [Abstract] [Full Text] [PDF]  

MSH6 and MSH3 Are Rarely Involved in Genetic Predisposition to Nonpolypotic Colon Cancer

Jiaqi Huang, Shannon A. Kuismanen, Tao Liu, Robert B. Chadwick, Cheryl K. Johnson, Michael W. Stevens, Samuel K. Richards, Julie E. Meek, Xin Gao, Fred A. Wright, Jukka-Pekka Mecklin, Heikki J. Järvinen, Henrik Grönberg, Marie Luise Bisgaard, Annika Lindblom, and Päivi Peltomäki
Cancer Res 2001 61: 1619-1623. [Abstract] [Full Text] [PDF]  

Cancer-specific Genomic Instability in Bronchial Lavage: A Molecular Tool for Lung Cancer Detection

Triantafillos Liloglou, Paul Maloney, George Xinarianos, Melanie Hulbert, Martin J. Walshaw, John R. Gosney, Lesley Turnbull, and John K. Field
Cancer Res 2001 61: 1624-1628. [Abstract] [Full Text] [PDF]  

Templated Nucleotide Addition and Immunoglobulin J_H-Gene Utilization in t(11;14) Junctions: Implications for the Mechanism of Translocation and the Origin of Mantle Cell Lymphoma

Natascha Welzel, Trang Le, Rodrig Marculescu, Gerlinde Mitterbauer, Andreas Chott, Christiane Pott, Michael Kneba, Ming-Qing Du, Rajko Kusec, Johannes Drach, Markus Raderer, Christine Mannhalter, Klaus Lechner, Bertrand Nadel, and Ulrich Jaeger
Cancer Res 2001 61: 1629-1636. [Abstract] [Full Text] [PDF]  

Tumor Biology:

Receptor Activator of Nuclear Factor B Ligand (RANKL) Is a Key Molecule of Osteoclast Formation for Bone Metastasis in a Newly Developed Model of Human Neuroblastoma

Toshimi Michigami, Miyuki Ihara-Watanabe, Miwa Yamazaki, and Keiichi Ozono
Cancer Res 2001 61: 1637-1644. [Abstract] [Full Text] [PDF]  

Anticancer Agents Sensitize Tumor Cells to Tumor Necrosis Factor-related Apoptosis-inducing Ligand-mediated Caspase-8 Activation and Apoptosis

Sandrine Lacour, Arlette Hammann, Anne Wotawa, Laurent Corcos, Eric Solary, and Marie-Thérèse Dimanche-Boitrel
Cancer Res 2001 61: 1645-1651. [Abstract] [Full Text] [PDF]  

Identification of CGA as a Novel Estrogen Receptor-responsive Gene in Breast Cancer: An Outstanding Candidate Marker to Predict the Response to Endocrine Therapy

Ivan Bièche, Béatrice Parfait, Vivianne Le Doussal, Martine Olivi, Marie-Christine Rio, Rosette Lidereau, and Michel Vidaud
Cancer Res 2001 61: 1652-1658. [Abstract] [Full Text] [PDF]  

DNA Fragments in the Blood Plasma of Cancer Patients: Quantitations and Evidence for Their Origin from Apoptotic and Necrotic Cells

Sabine Jahr, Hannes Hentze, Sabine Englisch, Dieter Hardt, Frank O. Fackelmayer, Rolf-Dieter Hesch, and Rolf Knippers
Cancer Res 2001 61: 1659-1665. [Abstract] [Full Text] [PDF]  

Prognostic Significance of Polysialic Acid Expression in Resected Non-Small Cell Lung Cancer

Fumihiro Tanaka, Yosuke Otake, Tatsuo Nakagawa, Yozo Kawano, Ryo Miyahara, Mio Li, Kazuhiro Yanagihara, Kenji Inui, Hiroki Oyanagi, Tomoko Yamada, Jun Nakayama, Ichiro Fujimoto, Kazuhiro Ikenaka, and Hiromi Wada
Cancer Res 2001 61: 1666-1670. [Abstract] [Full Text] [PDF]  

Geldanamycin Abrogates ErbB2 Association with Proteasome-resistant ß-Catenin in Melanoma Cells, Increases ß-Catenin-E-Cadherin Association, and Decreases ß-Catenin-sensitive Transcription

Paolo Bonvini, Won G. An, Angelo Rosolen, Phongmai Nguyen, Jane Trepel, Antonio Garcia de Herreros, Mireia Dunach, and Leonard M. Neckers
Cancer Res 2001 61: 1671-1677. [Abstract] [Full Text] [PDF]  

Identification of Genes Involved in Human Urothelial Cell-Matrix Interactions: Implications for the Progression Pathways of Malignant Urothelium

Barbara A. Smith, Wendy J. Kennedy, Patricia Harnden, Peter J. Selby, Ludwik K. Trejdosiewicz, and Jennifer Southgate
Cancer Res 2001 61: 1678-1685. [Abstract] [Full Text] [PDF]  

Catalytic Cleavage of the Androgen-regulated TMPRSS2 Protease Results in Its Secretion by Prostate and Prostate Cancer Epithelia

Daniel E. H. Afar, Igor Vivanco, Rene S. Hubert, James Kuo, Emily Chen, Douglas C. Saffran, Arthur B. Raitano, and Aya Jakobovits
Cancer Res 2001 61: 1686-1692. [Abstract] [Full Text] [PDF]  

Drug Resistance Induced by Ouabain via the Stimulation of MDR1 Gene Expression in Human Carcinomatous Pulmonary Cells

Franck Brouillard, Danielle Tondelier, Aleksander Edelman, and Maryvonne Baudouin-Legros
Cancer Res 2001 61: 1693-1698. [Abstract] [Full Text] [PDF]  

Overexpression of BCL-X_L Underlies the Molecular Basis for Resistance to Staurosporine-induced Apoptosis in PC-3 Cells

XiaoYing Li, Michela Marani, Roberta Mannucci, Berma Kinsey, Francesca Andriani, Ildo Nicoletti, Larry Denner, and Marco Marcelli
Cancer Res 2001 61: 1699-1706. [Abstract] [Full Text] [PDF]  

Anoikis and Metastatic Potential of Cloudman S91 Melanoma Cells

Zhenyu Zhu, Otto Sanchez-Sweatman, Xiaojun Huang, Robert Wiltrout, Rama Khokha, Qun Zhao, and Elieser Gorelik
Cancer Res 2001 61: 1707-1716. [Abstract] [Full Text] [PDF]  

Inhibition of Fibroblast Growth Factor/Fibroblast Growth Factor Receptor Activity in Glioma Cells Impedes Tumor Growth by Both Angiogenesis-dependent and -independent Mechanisms

Patrick Auguste, Demirkan B. Gürsel, Sylvie Lemière, Diana Reimers, Pedro Cuevas, Fernando Carceller, James P. Di Santo, and Andreas Bikfalvi
Cancer Res 2001 61: 1717-1726. [Abstract] [Full Text] [PDF]  

Up-Regulation of Vascular Endothelial Growth Factor in Breast Cancer Cells by the Heregulin-ß1-activated p38 Signaling Pathway Enhances Endothelial Cell Migration

Shunbin Xiong, Rebecca Grijalva, Lianglin Zhang, Nina T. Nguyen, Peter W. Pisters, Raphael E. Pollock, and Dihua Yu
Cancer Res 2001 61: 1727-1732. [Abstract] [Full Text] [PDF]  

Chemoprevention of Intestinal Polyposis in the Apc⁷¹⁶ Mouse by Rofecoxib, a Specific Cyclooxygenase-2 Inhibitor

Masanobu Oshima, Naomi Murai, Stacia Kargman, Meztli Arguello, Pauline Luk, Elizabeth Kwong, Makoto M. Taketo, and Jilly F. Evans
Cancer Res 2001 61: 1733-1740. [Abstract] [Full Text] [PDF]  

Mechanism of Functional Inactivation of a Li-Fraumeni Syndrome p53 That Has a Mutation Outside of the DNA-binding Domain

Jijie Gu, Hidehiko Kawai, Dmitri Wiederschain, and Zhi-Min Yuan
Cancer Res 2001 61: 1741-1746. [Abstract] [Full Text] [PDF]  

A Novel Serine-dependent Proteolytic Activity Is Responsible for Truncated Signal Transducer and Activator of Transcription Proteins in Acute Myeloid Leukemia Blasts

Zheng Xia, Robert R. Salzler, Daniel P. Kunz, Maria R. Baer, Latif Kazim, Heinz Baumann, and Meir Wetzler
Cancer Res 2001 61: 1747-1753. [Abstract] [Full Text] [PDF]  

Virology:

Identification of a Proviral Structure in Human Breast Cancer

Bingren Liu, Yue Wang, Stella M. Melana, Isabelle Pelisson, Vesna Najfeld, James F. Holland, and Beatriz G-T. Pogo
Cancer Res 2001 61: 1754-1759. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.