Advances in Brief:

Breast Cancer Metastatic Potential Correlates with a Breakdown in Homospecific and Heterospecific Gap Junctional Intercellular Communication

Marnie M. Saunders, M. Jabed Seraj, Zhongyong Li, Zhiyi Zhou, Cathy R. Winter, Danny R. Welch, and Henry J. Donahue
Cancer Res 2001 61: 1765-1767. [Abstract] [Full Text] [PDF]  

The 104–123 Amino Acid Sequence of the ß-domain of von Hippel-Lindau Gene Product Is Sufficient to Inhibit Renal Tumor Growth and Invasion

Kaustubh Datta, Christian Sundberg, S. Ananth Karumanchi, and Debabrata Mukhopadhyay
Cancer Res 2001 61: 1768-1775. [Abstract] [Full Text] [PDF]  

Suppression of a Squamous Cell Carcinoma (SCC)-related Serpin, SCC Antigen, Inhibits Tumor Growth with Increased Intratumor Infiltration of Natural Killer Cells

Yoshinori Suminami, Shigeki Nagashima, Akihiro Murakami, Shugo Nawata, Toshikazu Gondo, Hiroshi Hirakawa, Fumitaka Numa, Gary A. Silverman, and Hiroshi Kato
Cancer Res 2001 61: 1776-1780. [Abstract] [Full Text] [PDF]  

Noninvasive Imaging of _vß₃ Integrin Expression Using ¹⁸F-labeled RGD-containing Glycopeptide and Positron Emission Tomography

Roland Haubner, Hans-Jürgen Wester, Wolfgang A. Weber, Christian Mang, Sibylle I. Ziegler, Simon L. Goodman, Reingard Senekowitsch-Schmidtke, Horst Kessler, and Markus Schwaiger
Cancer Res 2001 61: 1781-1785. [Abstract] [Full Text] [PDF]  

Vascular Endothelial Growth Factor C Promotes Tumor Lymphangiogenesis and Intralymphatic Tumor Growth

Terhi Karpanen, Mikala Egeblad, Marika J. Karkkainen, Hajime Kubo, Seppo Ylä-Herttuala, Marja Jäättelä, and Kari Alitalo
Cancer Res 2001 61: 1786-1790. [Abstract] [Full Text] [PDF]  

Silica-induced Activation of c-Jun-NH₂-Terminal Amino Kinases, Protracted Expression of the Activator Protein-1 Proto-Oncogene, fra-1, and S-Phase Alterations Are Mediated via Oxidative Stress

Arti Shukla, Cynthia R. Timblin, Andrea K. Hubbard, Jonathan Bravman, and Brooke T. Mossman
Cancer Res 2001 61: 1791-1795. [Abstract] [Full Text] [PDF]  

Adenovirus Expressing RIZ1 in Tumor Suppressor Gene Therapy of Microsatellite-unstable Colorectal Cancers

Guang-Liang Jiang and Shi Huang
Cancer Res 2001 61: 1796-1798. [Abstract] [Full Text] [PDF]  

Geldanamycin and Its Analogue 17-Allylamino-17-demethoxygeldanamycin Lowers Bcr-Abl Levels and Induces Apoptosis and Differentiation of Bcr-Abl-positive Human Leukemic Blasts

Ramadevi Nimmanapalli, Erica O’Bryan, and Kapil Bhalla
Cancer Res 2001 61: 1799-1804. [Abstract] [Full Text] [PDF]  

Protease Pretreatment Increases the Efficacy of Adenovirus-mediated Gene Therapy for the Treatment of an Experimental Glioblastoma Model

Nagato Kuriyama, Hiroko Kuriyama, Carol M. Julin, Kathleen R. Lamborn, and Mark A. Israel
Cancer Res 2001 61: 1805-1809. [Abstract] [Full Text] [PDF]  

Proline Oxidase, Encoded by p53-induced Gene-6, Catalyzes the Generation of Proline-dependent Reactive Oxygen Species

Steven P. Donald, Xiao-Ya Sun, Chien-An A. Hu, Jian Yu, Jay M. Mei, David Valle, and James M. Phang
Cancer Res 2001 61: 1810-1815. [Abstract] [Full Text] [PDF]  

Tumorigenic Effect of Nonfunctional p53 or p21 in Mice Mutant in the Werner Syndrome Helicase

Michel Lebel, Robert D. Cardiff, and Philip Leder
Cancer Res 2001 61: 1816-1819. [Abstract] [Full Text] [PDF]  

Elevated Breast Cancer Risk in Irradiated BALB/c Mice Associates with Unique Functional Polymorphism of the Prkdc (DNA-dependent Protein Kinase Catalytic Subunit) Gene

Yongjia Yu, Ryuichi Okayasu, Michael M. Weil, Andy Silver, Maureen McCarthy, Ryan Zabriskie, Scott Long, Roger Cox, and Robert L. Ullrich
Cancer Res 2001 61: 1820-1824. [Abstract] [Full Text] [PDF]  

Gene Expression Profiling with Oligonucleotide Microarrays Distinguishes World Health Organization Grade of Oligodendrogliomas

Mark A. Watson, Arie Perry, Vikram Budhjara, Chindo Hicks, William D. Shannon, and Keith M. Rich
Cancer Res 2001 61: 1825-1829. [Abstract] [Full Text] [PDF]  

Hypoxia Inducible Factor (HIF-1a and HIF-2a) Expression in Early Esophageal Cancer and Response to Photodynamic Therapy and Radiotherapy

Michael I. Koukourakis, Alexandra Giatromanolaki, John Skarlatos, Luigi Corti, Stella Blandamura, Mario Piazza, Kevin C. Gatter, and Adrian L. Harris
Cancer Res 2001 61: 1830-1832. [Abstract] [Full Text] [PDF]  

Invasion-specific Genes in Malignancy: Serial Analysis of Gene Expression Comparisons of Primary and Passaged Cancers

Byungwoo Ryu, Jessa Jones, Michael A. Hollingsworth, Ralph H. Hruban, and Scott E. Kern
Cancer Res 2001 61: 1833-1838. [Abstract] [Full Text] [PDF]  

Aberrant Expression of HDMX Proteins in Tumor Cells Correlates with Wild-Type p53

Yolande F. M. Ramos, Robert Stad, Joline Attema, Lucy T. C. Peltenburg, Alex J. van der Eb, and Aart G. Jochemsen
Cancer Res 2001 61: 1839-1842. [Abstract] [Full Text] [PDF]  

Somatic Mutation of Mitochondrial DNA in Cancerous and Noncancerous Liver Tissue in Individuals with Hepatocellular Carcinoma

Manabu Nishikawa, Shuhei Nishiguchi, Susumu Shiomi, Akihiro Tamori, Noritoshi Koh, Tadashi Takeda, Shoji Kubo, Kazuhiro Hirohashi, Hiroaki Kinoshita, Eisuke Sato, and Masayasu Inoue
Cancer Res 2001 61: 1843-1845. [Abstract] [Full Text] [PDF]  

Target Cell-restricted Triggering of the CD95 (APO-1/Fas) Death Receptor with Bispecific Antibody Fragments

Gundram Jung, Ludger Grosse-Hovest, Peter H. Krammer, and Hans-Georg Rammensee
Cancer Res 2001 61: 1846-1848. [Abstract] [Full Text] [PDF]  

Biochemistry and Biophysics:

Increased Oxidative Stress in Ataxia Telangiectasia Evidenced by Alterations in Redox State of Brains from Atm-deficient Mice

Ariel Kamsler, Dvorah Daily, Ayala Hochman, Nora Stern, Yosef Shiloh, Galit Rotman, and Ari Barzilai
Cancer Res 2001 61: 1849-1854. [Abstract] [Full Text] [PDF]  

Phosphatidylinositol 3-Kinase Activity in Epidermal Growth Factor-stimulated Matrix Metalloproteinase-9 Production and Cell Surface Association

Shawn M. Ellerbroek, Jennifer M. Halbleib, Mario Benavidez, Janel K. Warmka, Elizabeth V. Wattenberg, M. Sharon Stack, and Laurie G. Hudson
Cancer Res 2001 61: 1855-1861. [Abstract] [Full Text] [PDF]  

XIAP Regulates Akt Activity and Caspase-3-dependent Cleavage during Cisplatin-induced Apoptosis in Human Ovarian Epithelial Cancer Cells

Eric Asselin, Gordon B. Mills, and Benjamin K. Tsang
Cancer Res 2001 61: 1862-1868. [Abstract] [Full Text] [PDF]  

Rapid Release of Intracellular Galectin-3 from Breast Carcinoma Cells by Fetuin

Wen-Qin Zhu and Josiah Ochieng
Cancer Res 2001 61: 1869-1873. [Abstract] [Full Text] [PDF]  

Carcinogenesis:

Sequential Analysis of Morphological and Biological Properties of ß-Catenin-accumulated Crypts, Provable Premalignant Lesions Independent of Aberrant Crypt Foci in Rat Colon Carcinogenesis

Yasuhiro Yamada, Naoki Yoshimi, Yoshinobu Hirose, Kengo Matsunaga, Masaki Katayama, Keiko Sakata, Masahito Shimizu, Toshiya Kuno, and Hideki Mori
Cancer Res 2001 61: 1874-1878. [Abstract] [Full Text] [PDF]  

A Clonal Growth Model: Time-course Simulations of Liver Foci Growth following Penta- or Hexachlorobenzene Treatment in a Medium-term Bioassay

Ying C. Ou, Rory B. Conolly, Russell S. Thomas, Yihua Xu, Melvin E. Andersen, Laura S. Chubb, Henry C. Pitot, and Raymond S. H. Yang
Cancer Res 2001 61: 1879-1889. [Abstract] [Full Text] [PDF]  

Clinical Investigations:

erbB2 Overexpression on Occult Metastatic Cells in Bone Marrow Predicts Poor Clinical Outcome of Stage I–III Breast Cancer Patients

Stephan Braun, Günter Schlimok, Isabella Heumos, Gerhard Schaller, Lutz Riethdorf, Gert Riethmüller, and Klaus Pantel
Cancer Res 2001 61: 1890-1895. [Abstract] [Full Text] [PDF]  

Heterogeneous Nuclear Ribonucleoprotein B1 as Early Cancer Biomarker for Occult Cancer of Human Lungs and Bronchial Dysplasia

Eisaburo Sueoka, Naoko Sueoka, Yuri Goto, Satoru Matsuyama, Hitoshi Nishimura, Masami Sato, Shigefumi Fujimura, Hiroshige Chiba, and Hirota Fujiki
Cancer Res 2001 61: 1896-1902. [Abstract] [Full Text] [PDF]  

Key Importance of the Helicobacter pylori Adherence Factor Blood Group Antigen Binding Adhesin during Chronic Gastric Inflammation

Christian Prinz, Martin Schöniger, Roland Rad, Ingrid Becker, Erwin Keiditsch, Stephan Wagenpfeil, Meinhard Classen, Thomas Rösch, Wolfgang Schepp, and Markus Gerhard
Cancer Res 2001 61: 1903-1909. [Abstract] [Full Text] [PDF]  

Endocrinology:

Overexpression of Aromatase Leads to Hyperplasia and Changes in the Expression of Genes Involved in Apoptosis, Cell Cycle, Growth, and Tumor Suppressor Functions in the Mammary Glands of Transgenic Mice

Nameer Kirma, Kiran Gill, Usha Mandava, and Rajeshwar Rao Tekmal
Cancer Res 2001 61: 1910-1918. [Abstract] [Full Text] [PDF]  

Evaluation of Androgen, Estrogen (ER and ERß), and Progesterone Receptor Expression in Human Prostate Cancer by Real-Time Quantitative Reverse Transcription-Polymerase Chain Reaction Assays

Alain Latil, Ivan Bièche, Dominique Vidaud, Rosette Lidereau, Philippe Berthon, Olivier Cussenot, and Michel Vidaud
Cancer Res 2001 61: 1919-1926. [Abstract] [Full Text] [PDF]  

Epidemiology and Prevention:

Modulation of Experimental Colon Tumorigenesis by Types and Amounts of Dietary Fatty Acids

Chinthalapally V. Rao, Yoshinobu Hirose, Cooma Indranie, and Bandaru S. Reddy
Cancer Res 2001 61: 1927-1933. [Abstract] [Full Text] [PDF]  

Human Papillomavirus 16 and 18 L1 Serology Compared across Anogenital Cancer Sites

Joseph J. Carter, Margaret M. Madeleine, Katherine Shera, Stephen M. Schwartz, Kara L. Cushing-Haugen, Gregory C. Wipf, Peggy Porter, Janet R. Daling, James K. McDougall, and Denise A. Galloway
Cancer Res 2001 61: 1934-1940. [Abstract] [Full Text] [PDF]  

Experimental Therapeutics:

Localization of a Human Reduced Folate Carrier Protein in the Mitochondrial as Well as the Cell Membrane of Leukemia Cells

Tanya M. Trippett, Shawna Garcia, Katia Manova, Roshni Mody, Leona Cohen-Gould, Wayne Flintoff, and Joseph R. Bertino
Cancer Res 2001 61: 1941-1947. [Abstract] [Full Text] [PDF]  

Vascular Attack by 5,6-Dimethylxanthenone-4-acetic Acid Combined with B7.1 (CD80)-mediated Immunotherapy Overcomes Immune Resistance and Leads to the Eradication of Large Tumors and Multiple Tumor Foci

Jagat R. Kanwar, Rupinder K. Kanwar, Sushil Pandey, Lai-Ming Ching, and Geoffrey W. Krissansen
Cancer Res 2001 61: 1948-1956. [Abstract] [Full Text] [PDF]  

p53 Effects Both the Duration of G₂/M Arrest and the Fate of Temozolomide-treated Human Glioblastoma Cells

Yuichi Hirose, Mitchel S. Berger, and Russell O. Pieper
Cancer Res 2001 61: 1957-1963. [Abstract] [Full Text] [PDF]  

Characterization of a Novel Topoisomerase I Mutation from a Camptothecin-resistant Human Prostate Cancer Cell Line

Yoshimasa Urasaki, Gary S. Laco, Phillipe Pourquier, Yuji Takebayashi, Glenda Kohlhagen, Christopher Gioffre, Hongliang Zhang, Devasis Chatterjee, Panayotis Pantazis, and Yves Pommier
Cancer Res 2001 61: 1964-1969. [Abstract] [Full Text] [PDF]  

Targeting of Aluminum (III) Phthalocyanine Tetrasulfonate by Use of Internalizing Monoclonal Antibodies: Improved Efficacy in Photodynamic Therapy

Maarten B. Vrouenraets, Gerard W. M. Visser, Marijke Stigter, Hugo Oppelaar, Gordon B. Snow, and Guus A. M. S. van Dongen
Cancer Res 2001 61: 1970-1975. [Abstract] [Full Text] [PDF]  

T-Cell Activation by Recombinant Receptors: CD28 Costimulation Is Required for Interleukin 2 Secretion and Receptor-mediated T-Cell Proliferation but Does Not Affect Receptor-mediated Target Cell Lysis

Andreas Hombach, Dagmar Sent, Claudia Schneider, Claudia Heuser, Dimitra Koch, Christoph Pohl, Barbara Seliger, and Hinrich Abken
Cancer Res 2001 61: 1976-1982. [Abstract] [Full Text] [PDF]  

Pharmacological and Toxicological Aspects of 4-Demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin (PNU-159548): A Novel Antineoplastic Agent

Cristina Geroni, Marina Ripamonti, Claudio Arrigoni, Francesco Fiorentini, Laura Capolongo, Donatella Moneta, Sergio Marchini, Paola Della Torre, Clara Albanese, Maria Grazia Lamparelli, Marina Ciomei, Rosaria Rossi, and Michele Caruso
Cancer Res 2001 61: 1983-1990. [Abstract] [Full Text] [PDF]  

4-Demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin (PNU-159548), a Novel Anticancer Agent Active against Tumor CellLines with Different Resistance Mechanisms

Sergio Marchini, Giovanna Damia, Massimo Broggini, Giulia Pennella, Marina Ripamonti, Aurelio Marsiglio, and Cristina Geroni
Cancer Res 2001 61: 1991-1995. [Abstract] [Full Text] [PDF]  

Experimental Chronotherapy of Mouse Mammary Adenocarcinoma MA13/C with Docetaxel and Doxorubicin as Single Agents and in Combination

T. G. Granda, E. Filipski, R. M. D’Attino, P. Vrignaud, A. Anjo, M. C. Bissery, and F. Lévi
Cancer Res 2001 61: 1996-2001. [Abstract] [Full Text] [PDF]  

Effects of Chemotherapy by 1,3-Bis(2-chloroethyl)-1-nitrosourea on Single-Quantum- and Triple-Quantum-filtered ²³Na and ³¹P Nuclear Magnetic Resonance of the Subcutaneously Implanted 9L Glioma

Patrick M. Winter, Harish Poptani, and Navin Bansal
Cancer Res 2001 61: 2002-2007. [Abstract] [Full Text] [PDF]  

Response of LNCaP Spheroids after Treatment with an -Particle Emitter (²¹³Bi)-labeled Anti-Prostate-specific Membrane Antigen Antibody (J591)

Åse M. Ballangrud, Wei-Hong Yang, David E. Charlton, Michael R. McDevitt, Klaus A. Hamacher, Katherine S. Panageas, Dangshe Ma, Neil H. Bander, David A. Scheinberg, and George Sgouros
Cancer Res 2001 61: 2008-2014. [Abstract] [Full Text] [PDF]  

Immunology:

Vascular Endothelial Growth Factor Effects on Nuclear Factor-B Activation in Hematopoietic Progenitor Cells

Mikhail M. Dikov, Tsunehiro Oyama, Pingyan Cheng, Takamune Takahashi, Keiko Takahashi, Tanya Sepetavec, Byard Edwards, Yasushi Adachi, Sorena Nadaf, Thomas Daniel, Dmitry I. Gabrilovich, and David P. Carbone
Cancer Res 2001 61: 2015-2021. [Abstract] [Full Text] [PDF]  

Stimulation of ß₁ Integrin Down-Regulates ICAM-1 Expression and ICAM-1-dependent Adhesion of Lung Cancer Cells through Focal Adhesion Kinase

Manabu Yasuda, Yoshiya Tanaka, Masahito Tamura, Koichi Fujii, Masakazu Sugaya, Tomoko So, Mitsuhiro Takenoyama, and Kosei Yasumoto
Cancer Res 2001 61: 2022-2030. [Abstract] [Full Text] [PDF]  

Divergent Effects of 4-1BB Antibodies on Antitumor Immunity and on Tumor-reactive T-Cell Generation

Julian A. Kim, Bruce J. Averbook, Kathleen Chambers, Kevin Rothchild, Jorgen Kjaergaard, Robert Papay, and Suyu Shu
Cancer Res 2001 61: 2031-2037. [Abstract] [Full Text] [PDF]  

Molecular Basis of T Cell-mediated Recognition of Pancreatic Cancer Cells

Masaaki Ito, Shigeki Shichijo, Naotake Tsuda, Mika Ochi, Nanae Harashima, Norio Saito, and Kyogo Itoh
Cancer Res 2001 61: 2038-2046. [Abstract] [Full Text] [PDF]  

Melanoma Patients Respond to a Cytotoxic T Lymphocyte-defined Self-Peptide with Diverse and Nonoverlapping T-Cell Receptor Repertoires

Pierre-Yves Dietrich, Paul R. Walker, Anne-Lise Quiquerez, Gaelle Perrin, Valerie Dutoit, Danielle Liénard, Philippe Guillaume, Jean-Charles Cerottini, Pedro Romero, and Danila Valmori
Cancer Res 2001 61: 2047-2054. [Abstract] [Full Text] [PDF]  

Identification of a Tissue-specific Putative Transcription Factor in Breast Tissue by Serological Screening of a Breast Cancer Library

Dirk Jäger, Elisabeth Stockert, Ali O. Güre, Matthew J. Scanlan, Julia Karbach, Elke Jäger, Alexander Knuth, Lloyd J. Old, and Yao-Tseng Chen
Cancer Res 2001 61: 2055-2061. [Abstract] [Full Text] [PDF]  

T Cell-dependent Antitumor Immunity Mediated by Secondary Lymphoid Tissue Chemokine: Augmentation of Dendritic Cell-based Immunotherapy

Christopher J. Kirk, Dennis Hartigan-O’Connor, Brian J. Nickoloff, Jeffrey S. Chamberlain, Martin Giedlin, Lea Aukerman, and James J. Mulé
Cancer Res 2001 61: 2062-2070. [Abstract] [Full Text] [PDF]  

Molecular Biology and Genetics:

Regulation of Growth and Tumorigenicity of Breast Cancer Cells by the Low Molecular Weight GTPase Rad and Nm23

Yu-Hua Tseng, David Vicent, Jianhua Zhu, Yulian Niu, Adewale Adeyinka, Julie S. Moyers, Peter H. Watson, and C. Ronald Kahn
Cancer Res 2001 61: 2071-2079. [Abstract] [Full Text] [PDF]  

Oct-2 and Bob-1 Deficiency in Hodgkin and Reed Sternberg Cells

Daniel Re, Markus Müschen, Tahamtan Ahmadi, Claudia Wickenhauser, Andrea Staratschek-Jox, Udo Holtick, Volker Diehl, and Jürgen Wolf
Cancer Res 2001 61: 2080-2084. [Abstract] [Full Text] [PDF]  

Activation of ß-Catenin during Hepatocarcinogenesis in Transgenic Mouse Models: Relationship to Phenotype and Tumor Grade

Diego F. Calvisi, Valentina M. Factor, Roberto Loi, and Snorri S. Thorgeirsson
Cancer Res 2001 61: 2085-2091. [Abstract] [Full Text] [PDF]  

Increased Loss of Chromosome 9p21 but not p16 Inactivation in Primary Non-Small Cell Lung Cancer from Smokers

Montserrat Sanchez-Cespedes, P. Anthony Decker, Kara M. Doffek, Manel Esteller, William H. Westra, Enas A. Alawi, James G. Herman, Michael J. Demeure, David Sidransky, and Steven A. Ahrendt
Cancer Res 2001 61: 2092-2096. [Abstract] [Full Text] [PDF]  

Stabilized ß-Catenin Immortalizes Colonic Epithelial Cells

Rebecca A. Wagenaar, Howard C. Crawford, and Lynn M. Matrisian
Cancer Res 2001 61: 2097-2104. [Abstract] [Full Text] [PDF]  

p27^Kip1 Is Required for PTEN-induced G₁ Growth Arrest

Alexander R. Gottschalk, Daniel Basila, Michelle Wong, Nicholas M. Dean, Christian H. Brandts, David Stokoe, and Daphne A. Haas-Kogan
Cancer Res 2001 61: 2105-2111. [Abstract] [Full Text] [PDF]  

SMAD3 Represses Androgen Receptor-mediated Transcription

Steven A. Hayes, Mark Zarnegar, Manju Sharma, Fajun Yang, Donna M. Peehl, Peter ten Dijke, and Zijie Sun
Cancer Res 2001 61: 2112-2118. [Abstract] [Full Text] [PDF]  

Mapping the Sites of Putative Tumor Suppressor Genes at 6p25 and 6p21.3 in Cervical Carcinoma: Occurrence of Allelic Deletions in Precancerous Lesions

Anupam Chatterjee, Hugo Arias Pulido, Sanjay Koul, Nestor Beleño, Ana Perilla, Hector Posso, Mahesh Manusukhani, and Vundavalli V. V. S. Murty
Cancer Res 2001 61: 2119-2123. [Abstract] [Full Text] [PDF]  

Microsatellite Instability Occurs in Distinct Subtypes of Pediatric but not Adult Central Nervous System Tumors

Michelle Alonso, Richard Hamelin, Mimi Kim, Kara Porwancher, Tammy Sung, Preeti Parhar, Douglas C. Miller, and Elizabeth W. Newcomb
Cancer Res 2001 61: 2124-2128. [Abstract] [Full Text] [PDF]  

Genome-wide Analysis of Gene Expression in Human Hepatocellular Carcinomas Using cDNA Microarray: Identification of Genes Involved in Viral Carcinogenesis and Tumor Progression

Hiroshi Okabe, Seiji Satoh, Tatsushi Kato, Osamu Kitahara, Renpei Yanagawa, Yoshio Yamaoka, Tatsuhiko Tsunoda, Yoichi Furukawa, and Yusuke Nakamura
Cancer Res 2001 61: 2129-2137. [Abstract] [Full Text] [PDF]  

Tumor Biology:

Expression of Vesicular Monoamine Transporters, Synaptosomal-associated Protein 25 and Syntaxin1: A Signature of Human Small Cell Lung Carcinoma

Lothar Graff, Florian Castrop, Markus Bauer, Heinz Höfler, and Manfred Gratzl
Cancer Res 2001 61: 2138-2144. [Abstract] [Full Text] [PDF]  

Angiopoietin-2 Is Related to Tumor Angiogenesis in Gastric Carcinoma: Possible in Vivo Regulation via Induction of Proteases

Tsuyoshi Etoh, Hiroshi Inoue, Shinji Tanaka, Graham F. Barnard, Seigo Kitano, and Masaki Mori
Cancer Res 2001 61: 2145-2153. [Abstract] [Full Text] [PDF]  

HuR, a RNA Stability Factor, Is Expressed in Malignant Brain Tumors and Binds to Adenine- and Uridine-rich Elements within the 3' Untranslated Regions of Cytokine and Angiogenic Factor mRNAs

L. Burt Nabors, G. Yancey Gillespie, Lualhati Harkins, and Peter H. King
Cancer Res 2001 61: 2154-2161. [Abstract] [Full Text] [PDF]  

The Gene for the Axonal Cell Adhesion Molecule TAX-1 Is Amplified and Aberrantly Expressed in Malignant Gliomas

David S. Rickman, Rachana Tyagi, Xiao-Xiang Zhu, Miroslav P. Bobek, Suzan Song, Mila Blaivas, David E. Misek, Mark A. Israel, David M. Kurnit, Donald A. Ross, Phillip E. Kish, and Samir M. Hanash
Cancer Res 2001 61: 2162-2168. [Abstract] [Full Text] [PDF]  

Expression of erbB-4/HER-4 Growth Factor Receptor Isoforms in Ovarian Cancer

Lynn M. R. Gilmour, Kenneth G. Macleod, Alison McCaig, William J. Gullick, John F. Smyth, and Simon P. Langdon
Cancer Res 2001 61: 2169-2176. [Abstract] [Full Text] [PDF]  

Establishment of a Novel Species- and Tissue-specific Metastasis Model of Human Prostate Cancer in Humanized Non-Obese Diabetic/Severe Combined Immunodeficient Mice Engrafted with Human Adult Lung and Bone

Hiroyuki Yonou, Tomoyuki Yokose, Tomoyuki Kamijo, Naoki Kanomata, Takahiro Hasebe, Kanji Nagai, Tadashi Hatano, Yoshihide Ogawa, and Atsushi Ochiai
Cancer Res 2001 61: 2177-2182. [Abstract] [Full Text] [PDF]  

Up-Regulation of Bcl-2 in Microvascular Endothelial Cells Enhances Intratumoral Angiogenesis and Accelerates Tumor Growth

Jacques E. Nör, Joan Christensen, Jianguo Liu, Martin Peters, David J. Mooney, Robert M. Strieter, and Peter J. Polverini
Cancer Res 2001 61: 2183-2188. [Abstract] [Full Text] [PDF]  

High Cancer Cell Death in Syngeneic Tumors Developed in Host Mice Deficient for the Stromelysin-3 Matrix Metalloproteinase

Anne Boulay, Régis Masson, Marie-Pierre Chenard, Mostapha El Fahime, Lydie Cassard, Jean-Pierre Bellocq, Catherine Sautèes-Fridman, Paul Basset, and Marie-Christine Rio
Cancer Res 2001 61: 2189-2193. [Abstract] [Full Text] [PDF]  

Role of Phosphatidylinositol 3-Kinase-Akt Pathway in Nucleophosmin/Anaplastic Lymphoma Kinase-mediated Lymphomagenesis

Artur Slupianek, Margaret Nieborowska-Skorska, Grazyna Hoser, Andrea Morrione, Miroslaw Majewski, Liquan Xue, Stephan W. Morris, Mariusz A. Wasik, and Tomasz Skorski
Cancer Res 2001 61: 2194-2199. [Abstract] [Full Text] [PDF]  

Aberrant Activation of c-kit Protects Colon Carcinoma Cells against Apoptosis and Enhances Their Invasive Potential

Graziella Bellone, Anna Carbone, Nadia Sibona, Ornella Bosco, Daniela Tibaudi, Carlo Smirne, Tiziana Martone, Claudia Gramigni, Michele Camandona, Giorgio Emanuelli, and Ulrich Rodeck
Cancer Res 2001 61: 2200-2206. [Abstract] [Full Text] [PDF]  

Radiation Therapy to a Primary Tumor Accelerates Metastatic Growth in Mice

Kevin Camphausen, Marsha A. Moses, Wolf-Dietrich Beecken, Mohamed K. Khan, Judah Folkman, and Michael S. O’Reilly
Cancer Res 2001 61: 2207-2211. [Abstract] [Full Text] [PDF]  

Centrosome Defects Can Account for Cellular and Genetic Changes That Characterize Prostate Cancer Progression

German A. Pihan, Aruna Purohit, Janice Wallace, Raji Malhotra, Lance Liotta, and Stephen J. Doxsey
Cancer Res 2001 61: 2212-2219. [Abstract] [Full Text] [PDF]  

Altered Expression of Ape1/ref-1 in Germ Cell Tumors and Overexpression in NT2 Cells Confers Resistance to Bleomycin and Radiation

Kent A. Robertson, Heather A. Bullock, Yi Xu, Renee Tritt, Erika Zimmerman, Thomas M. Ulbright, Richard S. Foster, Lawrence H. Einhorn, and Mark R. Kelley
Cancer Res 2001 61: 2220-2225. [Abstract] [Full Text] [PDF]  

Clinicopathological Significance of Core 2 ß1,6-N-Acetylglucosaminyltransferase Messenger RNA Expressed in the Pulmonary Adenocarcinoma Determined by in Situ Hybridization

Emi Machida, Jun Nakayama, Jun Amano, and Minoru Fukuda
Cancer Res 2001 61: 2226-2231. [Abstract] [Full Text] [PDF]  

Inhibition of Angiogenesis and Tumor Growth by SCH221153, a Dual _vß₃ and _vß₅ Integrin Receptor Antagonist

C. Chandra Kumar, Michael Malkowski, Zizhang Yin, Elena Tanghetti, Bo Yaremko, Terry Nechuta, Judy Varner, Ming Liu, Elizabeth M. Smith, Bernie Neustadt, Marco Presta, and Lydia Armstrong
Cancer Res 2001 61: 2232-2238. [Abstract] [Full Text] [PDF]  

A Probasin-Large T Antigen Transgenic Mouse Line Develops Prostate Adenocarcinoma and Neuroendocrine Carcinoma with Metastatic Potential

Naoya Masumori, Tania Z. Thomas, Pierre Chaurand, Tom Case, Manik Paul, Susan Kasper, Richard M. Caprioli, Taiji Tsukamoto, Scott B. Shappell, and Robert J. Matusik
Cancer Res 2001 61: 2239-2249. [Abstract] [Full Text] [PDF]  

Tumor Necrosis Factor and Interleukin 11 Secreted by Malignant Breast Epithelial Cells Inhibit Adipocyte Differentiation by Selectively Down-Regulating CCAAT/Enhancer Binding Protein and Peroxisome Proliferator-activated Receptor : Mechanism of Desmoplastic Reaction

Li Meng, Jianfeng Zhou, Hironobu Sasano, Takashi Suzuki, Khaled M. Zeitoun, and Serdar E. Bulun
Cancer Res 2001 61: 2250-2255. [Abstract] [Full Text] [PDF]  

The Expression of Vascular Endothelial Growth Factor Correlates with Mutant p53 and Poor Prognosis in Human Breast Cancer

Barbro K. Linderholm, Thomas Lindahl, Lars Holmberg, Sigrid Klaar, Johan Lennerstrand, Roger Henriksson, and Jonas Bergh
Cancer Res 2001 61: 2256-2260. [Abstract] [Full Text] [PDF]  

Impaired -Interferon Signaling in Transitional Cell Carcinoma: Lack of p48 Expression in 5637 Cells

Surena F. Matin, Raymond R. Rackley, Provash C. Sadhukhan, Myung S. Kim, Andrew C. Novick, and Sudip K. Bandyopadhyay
Cancer Res 2001 61: 2261-2266. [Abstract] [Full Text] [PDF]  

Induction of ETS-1 and ETS-2 Transcription Factors Is Required for Thyroid Cell Transformation

Filomena de Nigris, Tiziana Mega, Nicole Berger, Maria Vittoria Barone, Massimo Santoro, Giuseppe Viglietto, Pasquale Verde, and Alfredo Fusco
Cancer Res 2001 61: 2267-2275. [Abstract] [Full Text] [PDF]  

Regulation of MMP-1 and MMP-2 Production through CD147/Extracellular Matrix Metalloproteinase Inducer Interactions

Jianxin Sun and Martin E. Hemler
Cancer Res 2001 61: 2276-2281. [Abstract] [Full Text] [PDF]  

Parathyroid Hormone-related Protein Induces Interleukin 8 Production by Prostate Cancer Cells via a Novel Intracrine Mechanism Not Mediated by its Classical Nuclear Localization Sequence

Aneeta Gujral, Douglas W. Burton, Robert Terkeltaub, and Leonard J. Deftos
Cancer Res 2001 61: 2282-2288. [Abstract] [Full Text] [PDF]  

The Farnesyltransferase Inhibitor L744,832 Reduces Hypoxia in Tumors Expressing Activated H-ras

Elizabeth Cohen-Jonathan, Sydney M. Evans, Cameron J. Koch, Ruth J. Muschel, W. Gillies McKenna, JunMin Wu, and Eric J. Bernhard
Cancer Res 2001 61: 2289-2293. [Abstract] [Full Text] [PDF]  

Cystemustine Induces Redifferentiation of Primary Tumors and Confers Protection against Secondary Tumor Growth in a Melanoma Murine Model

Aicha Demidem, Daniel Morvan, Janine Papon, Monique De Latour, and Jean Claude Madelmont
Cancer Res 2001 61: 2294-2300. [Abstract] [Full Text] [PDF]  

EphA2 Overexpression Causes Tumorigenesis of Mammary Epithelial Cells

Daniel P. Zelinski, Nicole Dodge Zantek, Jane C. Stewart, Armando R. Irizarry, and Michael S. Kinch
Cancer Res 2001 61: 2301-2306. [Abstract] [Full Text] [PDF]  

Distribution and Functional Consequences of Nucleotide Polymorphisms in the 3'-Untranslated Region of the Human Sep15 Gene

Ya Jun Hu, Konstantin V. Korotkov, Rajeshwari Mehta, Dolph L. Hatfield, Charles N. Rotimi, Amy Luke, T. Elaine Prewitt, Richard S. Cooper, Wendy Stock, Everett E. Vokes, M. Eileen Dolan, Vadim N. Gladyshev, and Alan M. Diamond
Cancer Res 2001 61: 2307-2310. [Abstract] [Full Text] [PDF]  

Up- and Down-Regulation of Granulocyte/Macrophage-Colony Stimulating Factor Activity in Murine Skin Increase Susceptibility to Skin Carcinogenesis by Independent Mechanisms

Amrit Mann, Kai Breuhahn, Peter Schirmacher, Arnd Wilhelmi, Carsten Beyer, Andrea Rosenau, Suat Özbek, Stefan Rose-John, and Manfred Blessing
Cancer Res 2001 61: 2311-2319. [Abstract] [Full Text] [PDF]  

Elevation of Breast Carcinoma Nm23-H1 Metastasis Suppressor Gene Expression and Reduced Motility by DNA Methylation Inhibition

Melanie T. Hartsough, Susan E. Clare, Michael Mair, Abdel G. Elkahloun, Dennis Sgroi, C. Kent Osborne, Gary Clark, and Patricia S. Steeg
Cancer Res 2001 61: 2320-2327. [Abstract] [Full Text] [PDF]  

Malignant Breast Epithelial Cells Stimulate Aromatase Expression via Promoter II in Human Adipose Fibroblasts: An Epithelial-Stromal Interaction in Breast Tumors Mediated by CCAAT/Enhancer Binding Protein ß

Jianfeng Zhou, Bilgin Gurates, Sijun Yang, Siby Sebastian, and Serdar E. Bulun
Cancer Res 2001 61: 2328-2334. [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Correspondence re: O. J. Arola et al., Acute Doxorubicin Cardiotoxicity Involves Cardiomyocyte Apoptosis. Cancer Res., 60: 1789–1792, 2000.

Holger W. Auner, Christoph Tinchon, Werner Linkesch, Gabriele Halwachs-Baumann, and Heinz Sill
Cancer Res 2001 61: 2335-2336. [Full Text] [PDF]  

Errata:

H. Sjögren et al., Cancer Res., 60:6832–6835, 2000

Cancer Res 2001 61: 2339 [Full Text]  

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