Reviews:

Mechanisms of Action of Arsenic Trioxide

Wilson H. Miller, Jr., Hyman M. Schipper, Janet S. Lee, Jack Singer, and Samuel Waxman
Cancer Res 2002 62: 3893-3903. [Abstract] [Full Text] [PDF]  

Advances in Brief:

TEL-AML1, Expressed from t(12;21) in Human Acute Lymphocytic Leukemia, Induces Acute Leukemia in Mice

Florence Bernardin, Yandan Yang, Rebecca Cleaves, Marianna Zahurak, Linzhao Cheng, Curt I. Civin, and Alan D. Friedman
Cancer Res 2002 62: 3904-3908. [Abstract] [Full Text] [PDF]  

Novel Therapy for Liver Cancer: Direct Intraarterial Injection of a Potent Inhibitor of ATP Production

Jean-Francois H. Geschwind, Young H. Ko, Michael S. Torbenson, Carolyn Magee, and Peter L. Pedersen
Cancer Res 2002 62: 3909-3913. [Abstract] [Full Text] [PDF]  

Development of Antitumor Immune Responses in Reconstituted Lymphopenic Hosts

Hong-Ming Hu, Christian H. Poehlein, Walter J. Urba, and Bernard A. Fox
Cancer Res 2002 62: 3914-3919. [Abstract] [Full Text] [PDF]  

Molecular Effects of the Herbal Compound PC-SPES: Identification of Activity Pathways in Prostate Carcinoma

Michael Bonham, Hugh Arnold, Bruce Montgomery, and Peter S. Nelson
Cancer Res 2002 62: 3920-3924. [Abstract] [Full Text] [PDF]  

A Hereditary Nonpolyposis Colorectal Carcinoma Case Associated with Hypermethylation of the MLH1 Gene in Normal Tissue and Loss of Heterozygosity of the Unmethylated Allele in the Resulting Microsatellite Instability-High Tumor

Isabella Gazzoli, Massimo Loda, Judy Garber, Sapna Syngal, and Richard D. Kolodner
Cancer Res 2002 62: 3925-3928. [Abstract] [Full Text] [PDF]  

SHPS-1: A Budding Molecule against Cancer Dissemination

Kumi Oshima, Kazuya Machida, Yasukatu Ichigotani, Yuji Nimura, Naoki Shirafuji, Michinari Hamaguchi, and Satoru Matsuda
Cancer Res 2002 62: 3929-3933. [Abstract] [Full Text] [PDF]  

Adenovirus-mediated Endostatin Delivery Results in Inhibition of Mammary Gland Tumor Growth in C3(1)/SV40 T-Antigen Transgenic Mice

Alfonso Calvo, Andrew L. Feldman, Steven K. Libutti, and Jeffrey E. Green
Cancer Res 2002 62: 3934-3938. [Abstract] [Full Text] [PDF]  

Comparison of Gene Expression Profiles between Hepatitis B Virus- and Hepatitis C Virus-infected Hepatocellular Carcinoma by Oligonucleotide Microarray Data on the Basis of a Supervised Learning Method

Norio Iizuka, Masaaki Oka, Hisafumi Yamada-Okabe, Naohide Mori, Takao Tamesa, Toshimasa Okada, Norikazu Takemoto, Akira Tangoku, Kenji Hamada, Hironobu Nakayama, Takanobu Miyamoto, Shunji Uchimura, and Yoshihiko Hamamoto
Cancer Res 2002 62: 3939-3944. [Abstract] [Full Text] [PDF]  

Loss of Retinoic Acid Receptor ß Gene Expression Is Linked to Aberrant Histone H3 Acetylation in Lung Cancer Cell Lines

Young-Ah Suh, Ho-Young Lee, Arvind Virmani, Jiemin Wong, Koren K. Mann, Wilson H. Miller, Jr., Adi Gazdar, and Jonathan M. Kurie
Cancer Res 2002 62: 3945-3949. [Abstract] [Full Text] [PDF]  

Drg1, a Novel Target for Modulating Sensitivity to CPT-11 in Colon Cancer Cells

Monica Motwani, Francis M. Sirotnak, Yuhong She, Therese Commes, and Gary K. Schwartz
Cancer Res 2002 62: 3950-3955. [Abstract] [Full Text] [PDF]  

Cyclooxygenase-2 Inhibitor Treatment Enhances Photodynamic Therapy-mediated Tumor Response

Angela Ferrario, Karl von Tiehl, Sam Wong, Marian Luna, and Charles J. Gomer
Cancer Res 2002 62: 3956-3961. [Abstract] [Full Text] [PDF]  

Hyaluronan-CD44s Signaling Regulates Matrix Metalloproteinase-2 Secretion in a Human Lung Carcinoma Cell Line QG90

Yanying Zhang, Aye Aye Thant, Kazuya Machida, Yasukatsu Ichigotani, Yuko Naito, Yukiko Hiraiwa, Takeshi Senga, Yasuyoshi Sohara, Satoru Matsuda, and Michinari Hamaguchi
Cancer Res 2002 62: 3962-3965. [Abstract] [Full Text] [PDF]  

Biochemistry and Biophysics:

Deficient Nonhomologous End-Joining Activity in Cell-free Extracts from Brca1-null Fibroblasts

Qing Zhong, Thomas G. Boyer, Phang-Lang Chen, and Wen-Hwa Lee
Cancer Res 2002 62: 3966-3970. [Abstract] [Full Text] [PDF]  

Clinical Investigations:

Combined Use of Oligonucleotide and Tissue Microarrays Identifies Cancer/Testis Antigens as Biomarkers in Lung Carcinoma

Michio Sugita, Mark Geraci, Bifeng Gao, Roger L. Powell, Fred R. Hirsch, Gary Johnson, Razvan Lapadat, Edward Gabrielson, Roy Bremnes, Paul A. Bunn, and Wilbur A. Franklin
Cancer Res 2002 62: 3971-3979. [Abstract] [Full Text] [PDF]  

Prognostically Important Chromosomal Aberrations in Soft Tissue Sarcomas: A Report of the Chromosomes and Morphology (CHAMP) Study Group

Fredrik Mertens, Ulf Strömberg, Nils Mandahl, Paola Dal Cin, Ivo De Wever, Christopher D. M. Fletcher, Felix Mitelman, Juan Rosai, Anders Rydholm, Raf Sciot, Giovanni Tallini, Herman Van den Berghe, Roberta Vanni, and Helena Willén
Cancer Res 2002 62: 3980-3984. [Abstract] [Full Text] [PDF]  

Endocrinology:

Antiestrogen ICI 182,780 Decreases Proliferation of Insulin-like Growth Factor I (IGF-I)-treated MCF-7 Cells without Inhibiting IGF-I Signaling

Hemant Varma and Susan E. Conrad
Cancer Res 2002 62: 3985-3991. [Abstract] [Full Text] [PDF]  

Epidemiology and Prevention:

Average Midrange Ultraviolet Radiation Flux and Time Outdoors Predict Melanoma Risk

Thomas R. Fears, Cameron C. Bird, DuPont Guerry, IV, Richard W. Sagebiel, Mitchell H. Gail, David E. Elder, Allan Halpern, Elizabeth A. Holly, Patricia Hartge, and Margaret A. Tucker
Cancer Res 2002 62: 3992-3996. [Abstract] [Full Text] [PDF]  

Growth Inhibition of Human Hepatoma Cells by Acyclic Retinoid Is Associated with Induction of p21^CIP1 and Inhibition of Expression of Cyclin D1

Masumi Suzui, Muneyuki Masuda, Jin T. E. Lim, Chris Albanese, Richard G. Pestell, and I. Bernard Weinstein
Cancer Res 2002 62: 3997-4006. [Abstract] [Full Text] [PDF]  

Experimental Therapeutics:

Hypoestoxide, a Natural Nonmutagenic Diterpenoid with Antiangiogenic and Antitumor Activity: Possible Mechanisms of Action

Emmanuel A. Ojo-Amaize, Emeka J. Nchekwube, Howard B. Cottam, Ruoli Bai, Pascal Verdier-Pinard, Vellalore N. Kakkanaiah, Judith A. Varner, Lorenzo Leoni, Joseph I. Okogun, Akinbo A. Adesomoju, Olusola A. Oyemade, and Ernest Hamel
Cancer Res 2002 62: 4007-4014. [Abstract] [Full Text] [PDF]  

PTK787/ZK 222584, a Specific Vascular Endothelial Growth Factor-Receptor Tyrosine Kinase Inhibitor, Affects the Anatomy of the Tumor Vascular Bed and the Functional Vascular Properties as Detected by Dynamic Enhanced Magnetic Resonance Imaging

Joachim Drevs, Ralph Müller-Driver, Christine Wittig, Stefan Fuxius, Norbert Esser, Harald Hugenschmidt, Moritz A. Konerding, Peter R. Allegrini, Jeanette Wood, Jürgen Hennig, Clemens Unger, and Dieter Marmé
Cancer Res 2002 62: 4015-4022. [Abstract] [Full Text] [PDF]  

Interleukin 2 Gene Transfer Prevents NKG2D Suppression and Enhances Antitumor Efficacy in Combination with Cisplatin for Head and Neck Squamous Cell Cancer

Daqing Li, Brian Ronson, Ming Guo, Shixi Liu, Jeffrey S. Bishop, David A. Van Echo, and Bert W. O’Malley, Jr.
Cancer Res 2002 62: 4023-4028. [Abstract] [Full Text] [PDF]  

Identification and Characterization of Nuclease-stabilized RNA Molecules That Bind Human Prostate Cancer Cells via the Prostate-specific Membrane Antigen

Shawn E. Lupold, Brian J. Hicke, Yun Lin, and Donald S. Coffey
Cancer Res 2002 62: 4029-4033. [Abstract] [Full Text] [PDF]  

Immunology:

Lymphotoxin-ß Receptor Immune Interaction Promotes Tumor Growth by Inducing Angiogenesis

Thomas Hehlgans, Benjamin Stoelcker, Peter Stopfer, Peter Müller, Grigore Cernaianu, Markus Guba, Markus Steinbauer, Sergei A. Nedospasov, Klaus Pfeffer, and Daniela N. Männel
Cancer Res 2002 62: 4034-4040. [Abstract] [Full Text] [PDF]  

Cancer-related Serological Recognition of Human Colon Cancer: Identification of Potential Diagnostic and Immunotherapeutic Targets

Matthew J. Scanlan, Sydney Welt, Claudia M. Gordon, Yao-Tseng Chen, Ali O. Gure, Elisabeth Stockert, Achim A. Jungbluth, Gerd Ritter, Dirk Jäger, Elke Jäger, Alexander Knuth, and Lloyd J. Old
Cancer Res 2002 62: 4041-4047. [Abstract] [Full Text] [PDF]  

Molecular Biology and Genetics:

The Association of Death-associated Protein Kinase Hypermethylation with Early Recurrence in Superficial Bladder Cancers

Yasuhiro Tada, Morimasa Wada, Ken-ichi Taguchi, Yasushi Mochida, Naoko Kinugawa, Masazumi Tsuneyoshi, Seiji Naito, and Michihiko Kuwano
Cancer Res 2002 62: 4048-4053. [Abstract] [Full Text] [PDF]  

The Fragile Histidine Triad/Common Chromosome Fragile Site 3B Locus and Repair-deficient Cancers

Bruce C. Turner, Michelle Ottey, Drazen B. Zimonjic, Magdalena Potoczek, Walter W. Hauck, Edward Pequignot, Catherine L. Keck-Waggoner, Cinzia Sevignani, C. Marcelo Aldaz, Peter A. McCue, Juan Palazzo, Kay Huebner, and Nicholas C. Popescu
Cancer Res 2002 62: 4054-4060. [Abstract] [Full Text] [PDF]  

Gastric Cancers Overexpress DARPP-32 and a Novel Isoform, t-DARPP

Wa’el El-Rifai, Michael F. Smith, Jr., Guolian Li, Andy Beckler, Virginia S. Carl, Elizabeth Montgomery, Sakari Knuutila, Christopher A. Moskaluk, Henry F. Frierson, Jr., and Steven M. Powell
Cancer Res 2002 62: 4061-4064. [Abstract] [Full Text] [PDF]  

Replication Failure, Genome Instability, and Increased Cancer Susceptibility in Mice with a Point Mutation in the DNA Ligase I Gene

Caroline Harrison, Ann-Marie Ketchen, Nicola J. Redhead, Maureen J. O’Sullivan, and David W. Melton
Cancer Res 2002 62: 4065-4074. [Abstract] [Full Text] [PDF]  

LCX, Leukemia-associated Protein with a CXXC Domain, Is Fused to MLL in Acute Myeloid Leukemia with Trilineage Dysplasia Having t(10;11)(q22;q23)

Ryoichi Ono, Tomohiko Taki, Takeshi Taketani, Masafumi Taniwaki, Hajime Kobayashi, and Yasuhide Hayashi
Cancer Res 2002 62: 4075-4080. [Abstract] [Full Text] [PDF]  

Late Activation of Apoptotic Pathways Plays a Negligible Role in Mediating the Cytotoxic Effects of Discodermolide and Epothilone B in Non-Small Cell Lung Cancer Cells

Linda E. Bröker, Cynthia Huisman, Carlos G. Ferreira, José A. Rodriguez, Frank A. E. Kruyt, and Giuseppe Giaccone
Cancer Res 2002 62: 4081-4088. [Abstract] [Full Text] [PDF]  

Alternative Translocation Breakpoint Cluster Region 5' to BCL-6 in B-cell Non-Hodgkin’s Lymphoma

Marion P. Butler, Shinsuke Iida, Daniela Capello, Davide Rossi, Pulivarthi H. Rao, Palanisamy Nallasivam, Diane C. Louie, Seeta Chaganti, Thomas Au, Randy D. Gascoyne, Gianluca Gaidano, Raju S. K. Chaganti, and Riccardo Dalla-Favera
Cancer Res 2002 62: 4089-4094. [Abstract] [Full Text] [PDF]  

Genes Involved in DNA Repair Are Mutational Targets in Endometrial Cancers with Microsatellite Instability

Vessela Vassileva, Anna Millar, Laurent Briollais, William Chapman, and Bharati Bapat
Cancer Res 2002 62: 4095-4099. [Abstract] [Full Text] [PDF]  

Transcript Map of the 3.7-Mb D19S112–D19S246 Candidate Tumor Suppressor Region on the Long Arm of Chromosome 19

Christian Hartmann, Loki Johnk, Gaspar Kitange, Yanhong Wu, Linda K. Ashworth, Robert B. Jenkins, and David N. Louis
Cancer Res 2002 62: 4100-4108. [Abstract] [Full Text] [PDF]  

Tumor Biology:

Noscapine Alters Microtubule Dynamics in Living Cells and Inhibits the Progression of Melanoma

Jaren W. Landen, Roland Lang, Steve J. McMahon, Nasser M. Rusan, Anne-Marie Yvon, Ashley W. Adams, Mia D. Sorcinelli, Ross Campbell, Paola Bonaccorsi, John C. Ansel, David R. Archer, Patricia Wadsworth, Cheryl A. Armstrong, and Harish C. Joshi
Cancer Res 2002 62: 4109-4114. [Abstract] [Full Text] [PDF]  

Centrosome Amplification and Overexpression of Aurora A Are Early Events in Rat Mammary Carcinogenesis

Thea M. Goepfert, Yetunde E. Adigun, Ling Zhong, Jason Gay, Daniel Medina, and William R. Brinkley
Cancer Res 2002 62: 4115-4122. [Abstract] [Full Text] [PDF]  

VEGF₁₆₅b, an Inhibitory Splice Variant of Vascular Endothelial Growth Factor, Is Down-Regulated in Renal Cell Carcinoma

David O. Bates, Tai-Gen Cui, Joanne M. Doughty, Matthias Winkler, Marto Sugiono, Jacqueline D. Shields, Danielle Peat, David Gillatt, and Steven J. Harper
Cancer Res 2002 62: 4123-4131. [Abstract] [Full Text] [PDF]  

Herceptin-induced Inhibition of Phosphatidylinositol-3 Kinase and Akt Is Required for Antibody-mediated Effects on p27, Cyclin D1, and Antitumor Action

F. Michael Yakes, Wichai Chinratanalab, Christoph A. Ritter, Walter King, Steven Seelig, and Carlos L. Arteaga
Cancer Res 2002 62: 4132-4141. [Abstract] [Full Text] [PDF]  

Ras Mediates Radioresistance through Both Phosphatidylinositol 3-Kinase-dependent and Raf-dependent but Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase Kinase-independent Signaling Pathways

Theresa M. Grana, Elena V. Rusyn, Hong Zhou, Carolyn I. Sartor, and Adrienne D. Cox
Cancer Res 2002 62: 4142-4150. [Abstract] [Full Text] [PDF]  

Epigenetic Factors Controlling the BRCA1 and BRCA2 Genes in Sporadic Ovarian Cancer

Kelvin Y. K. Chan, Hilmi Ozçelik, Annie N. Y. Cheung, Hextan Y. S. Ngan, and Ui-Soon Khoo
Cancer Res 2002 62: 4151-4156. [Abstract] [Full Text] [PDF]  

Overexpression of Epidermal Growth Factor Receptor in Urothelium Elicits Urothelial Hyperplasia and Promotes Bladder Tumor Growth

Jin Cheng, Hongying Huang, Zhong-Ting Zhang, Ellen Shapiro, Angel Pellicer, Tung-Tien Sun, and Xue-Ru Wu
Cancer Res 2002 62: 4157-4163. [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Correspondence re: A. H. Ree et al., Expression of a Novel Factor in Human Breast Cancer Cells with Metastatic Potential. Cancer Res., 59: 4675–4680, 1999

Jeffrey Scott Coker and Eric Davies
Cancer Res 2002 62: 4164-4165. [Full Text] [PDF]  

Reply

Anne Hansen Ree
Cancer Res 2002 62: 4165 [Full Text] [PDF]  

Correction:

Correction for vol 62, p 8

Cancer Res 2002 62: 4167 [Full Text] [PDF]  

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